Identification and Association of Single Nucleotide Polymorphisms of the FTO Gene with Indicators of Overweight and Obesity in a Young Mexican Population.
Genes
Chama-Avilés, Alonso A; Flores-Viveros, Karla Lucero KL; Cabrera-Ayala, Jorge Alberto JA; Aguilar-Galarza, Adriana A; García-Muñoz, Willebaldo W; Haddad-Talancón, Lorenza L; de Lourdes Anzures-Cortés, Ma M; Velázquez-Sánchez, Claudia C; Chávez-Servín, Jorge Luis JL; Anaya-Loyola, Miriam Aracely MA; García-Gasca, Teresa T; Rodríguez-García, Víctor Manuel VM; Moreno-Celis, Ulisses U
Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure.
Nature Communications
Levin, Michael G MG; Tsao, Noah L NL; Singhal, Pankhuri P; Liu, Chang C; Vy, Ha My T HMT; Paranjpe, Ishan I; Backman, Joshua D JD; Bellomo, Tiffany R TR; Bone, William P WP; Biddinger, Kiran J KJ; Hui, Qin Q; Dikilitas, Ozan O; Satterfield, Benjamin A BA; Yang, Yifan Y; Morley, Michael P MP; Bradford, Yuki Y; Burke, Megan M; Reza, Nosheen N; Charest, Brian B; , ; Judy, Renae L RL; Puckelwartz, Megan J MJ; Hakonarson, Hakon H; Khan, Atlas A; Kottyan, Leah C LC; Kullo, Iftikhar I; Luo, Yuan Y; McNally, Elizabeth M EM; Rasmussen-Torvik, Laura J LJ; Day, Sharlene M SM; Do, Ron R; Phillips, Lawrence S LS; Ellinor, Patrick T PT; Nadkarni, Girish N GN; Ritchie, Marylyn D MD; Arany, Zoltan Z; Cappola, Thomas P TP; Margulies, Kenneth B KB; Aragam, Krishna G KG; Haggerty, Christopher M CM; Joseph, Jacob J; Sun, Yan V YV; Voight, Benjamin F BF; Damrauer, Scott M SM
The Impact of Harsh Parenting on the Development of Obesity in Adulthood: An Examination of Epigenetic/Gene Expression Mediators Among African American Youth.
Frontiers In Cardiovascular Medicine
Lei, Man-Kit MK; Beach, Steven R H SRH; Simons, Ronald L RL; Ye, Kaixiong K
Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption.
Nature Communications
Karabegović, Irma I; Portilla-Fernandez, Eliana E; Li, Yang Y; Ma, Jiantao J; Maas, Silvana C E SCE; Sun, Daokun D; Hu, Emily A EA; Kühnel, Brigitte B; Zhang, Yan Y; Ambatipudi, Srikant S; Fiorito, Giovanni G; Huang, Jian J; Castillo-Fernandez, Juan E JE; Wiggins, Kerri L KL; de Klein, Niek N; Grioni, Sara S; Swenson, Brenton R BR; Polidoro, Silvia S; Treur, Jorien L JL; Cuenin, Cyrille C; Tsai, Pei-Chien PC; Costeira, Ricardo R; Chajes, Veronique V; Braun, Kim K; Verweij, Niek N; Kretschmer, Anja A; Franke, Lude L; van Meurs, Joyce B J JBJ; Uitterlinden, André G AG; de Knegt, Robert J RJ; Ikram, M Arfan MA; Dehghan, Abbas A; Peters, Annette A; Schöttker, Ben B; Gharib, Sina A SA; Sotoodehnia, Nona N; Bell, Jordana T JT; Elliott, Paul P; Vineis, Paolo P; Relton, Caroline C; Herceg, Zdenko Z; Brenner, Hermann H; Waldenberger, Melanie M; Rebholz, Casey M CM; Voortman, Trudy T; Pan, Qiuwei Q; Fornage, Myriam M; Levy, Daniel D; Kayser, Manfred M; Ghanbari, Mohsen M
Coffee consumption and risk of breast cancer: A Mendelian randomization study.
Plos One
Ellingjord-Dale, Merete M; Papadimitriou, Nikos N; Katsoulis, Michail M; Yee, Chew C; Dimou, Niki N; Gill, Dipender D; Aune, Dagfinn D; Ong, Jue-Sheng JS; MacGregor, Stuart S; Elsworth, Benjamin B; Lewis, Sarah J SJ; Martin, Richard M RM; Riboli, Elio E; Tsilidis, Konstantinos K KK
Childhood adversity is linked to adult health among African Americans via adolescent weight gain and effects are genetically moderated.
Development And Psychopathology
Beach, Steven R H SRH; Ong, Mei Ling ML; Lei, Man-Kit MK; Klopack, Eric E; Carter, Sierra E SE; Simons, Ronald L RL; Gibbons, Frederick X FX; Lavner, Justin A JA; Philibert, Robert A RA; Ye, Kaixiong K
Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.
Plos Genetics
Ng, Maggie C Y MCY; Graff, Mariaelisa M; Lu, Yingchang Y; Justice, Anne E AE; Mudgal, Poorva P; Liu, Ching-Ti CT; Young, Kristin K; Yanek, Lisa R LR; Feitosa, Mary F MF; Wojczynski, Mary K MK; Rand, Kristin K; Brody, Jennifer A JA; Cade, Brian E BE; Dimitrov, Latchezar L; Duan, Qing Q; Guo, Xiuqing X; Lange, Leslie A LA; Nalls, Michael A MA; Okut, Hayrettin H; Tajuddin, Salman M SM; Tayo, Bamidele O BO; Vedantam, Sailaja S; Bradfield, Jonathan P JP; Chen, Guanjie G; Chen, Wei-Min WM; Chesi, Alessandra A; Irvin, Marguerite R MR; Padhukasahasram, Badri B; Smith, Jennifer A JA; Zheng, Wei W; Allison, Matthew A MA; Ambrosone, Christine B CB; Bandera, Elisa V EV; Bartz, Traci M TM; Berndt, Sonja I SI; Bernstein, Leslie L; Blot, William J WJ; Bottinger, Erwin P EP; Carpten, John J; Chanock, Stephen J SJ; Chen, Yii-Der Ida YI; Conti, David V DV; Cooper, Richard S RS; Fornage, Myriam M; Freedman, Barry I BI; Garcia, Melissa M; Goodman, Phyllis J PJ; Hsu, Yu-Han H YH; Hu, Jennifer J; Huff, Chad D CD; Ingles, Sue A SA; John, Esther M EM; Kittles, Rick R; Klein, Eric E; Li, Jin J; McKnight, Barbara B; Nayak, Uma U; Nemesure, Barbara B; Ogunniyi, Adesola A; Olshan, Andrew A; Press, Michael F MF; Rohde, Rebecca R; Rybicki, Benjamin A BA; Salako, Babatunde B; Sanderson, Maureen M; Shao, Yaming Y; Siscovick, David S DS; Stanford, Janet L JL; Stevens, Victoria L VL; Stram, Alex A; Strom, Sara S SS; Vaidya, Dhananjay D; Witte, John S JS; Yao, Jie J; Zhu, Xiaofeng X; Ziegler, Regina G RG; Zonderman, Alan B AB; Adeyemo, Adebowale A; Ambs, Stefan S; Cushman, Mary M; Faul, Jessica D JD; Hakonarson, Hakon H; Levin, Albert M AM; Nathanson, Katherine L KL; Ware, Erin B EB; Weir, David R DR; Zhao, Wei W; Zhi, Degui D; , ; Arnett, Donna K DK; Grant, Struan F A SFA; Kardia, Sharon L R SLR; Oloapde, Olufunmilayo I OI; Rao, D C DC; Rotimi, Charles N CN; Sale, Michele M MM; Williams, L Keoki LK; Zemel, Babette S BS; Becker, Diane M DM; Borecki, Ingrid B IB; Evans, Michele K MK; Harris, Tamara B TB; Hirschhorn, Joel N JN; Li, Yun Y; Patel, Sanjay R SR; Psaty, Bruce M BM; Rotter, Jerome I JI; Wilson, James G JG; Bowden, Donald W DW; Cupples, L Adrienne LA; Haiman, Christopher A CA; Loos, Ruth J F RJF; North, Kari E KE
Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci.
Human Genetics
Fernández-Rhodes, Lindsay L; Gong, Jian J; Haessler, Jeffrey J; Franceschini, Nora N; Graff, Mariaelisa M; Nishimura, Katherine K KK; Wang, Yujie Y; Highland, Heather M HM; Yoneyama, Sachiko S; Bush, William S WS; Goodloe, Robert R; Ritchie, Marylyn D MD; Crawford, Dana D; Gross, Myron M; Fornage, Myriam M; Buzkova, Petra P; Tao, Ran R; Isasi, Carmen C; Avilés-Santa, Larissa L; Daviglus, Martha M; Mackey, Rachel H RH; Houston, Denise D; Gu, C Charles CC; Ehret, Georg G; Nguyen, Khanh-Dung H KH; Lewis, Cora E CE; Leppert, Mark M; Irvin, Marguerite R MR; Lim, Unhee U; Haiman, Christopher A CA; Le Marchand, Loic L; Schumacher, Fredrick F; Wilkens, Lynne L; Lu, Yingchang Y; Bottinger, Erwin P EP; Loos, Ruth J L RJL; Sheu, Wayne H-H WH; Guo, Xiuqing X; Lee, Wen-Jane WJ; Hai, Yang Y; Hung, Yi-Jen YJ; Absher, Devin D; Wu, I-Chien IC; Taylor, Kent D KD; Lee, I-Te IT; Liu, Yeheng Y; Wang, Tzung-Dau TD; Quertermous, Thomas T; Juang, Jyh-Ming J JJ; Rotter, Jerome I JI; Assimes, Themistocles T; Hsiung, Chao A CA; Chen, Yii-Der Ida YI; Prentice, Ross R; Kuller, Lewis H LH; Manson, JoAnn E JE; Kooperberg, Charles C; Smokowski, Paul P; Robinson, Whitney R WR; Gordon-Larsen, Penny P; Li, Rongling R; Hindorff, Lucia L; Buyske, Steven S; Matise, Tara C TC; Peters, Ulrike U; North, Kari E KE
Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer.
Cancer Epidemiology
Yang, Baiyu B; Thrift, Aaron P AP; Figueiredo, Jane C JC; Jenkins, Mark A MA; Schumacher, Fredrick R FR; Conti, David V DV; Lin, Yi Y; Win, Aung Ko AK; Limburg, Paul J PJ; Berndt, Sonja I SI; Brenner, Hermann H; Chan, Andrew T AT; Chang-Claude, Jenny J; Hoffmeister, Michael M; Hudson, Thomas J TJ; Marchand, Loïc Le LL; Newcomb, Polly A PA; Slattery, Martha L ML; White, Emily E; Peters, Ulrike U; Casey, Graham G; Campbell, Peter T PT
Low copy number of the salivary amylase gene predisposes to obesity.
Nature Genetics
Falchi, Mario M; El-Sayed Moustafa, Julia Sarah JS; Takousis, Petros P; Pesce, Francesco F; Bonnefond, Amélie A; Andersson-Assarsson, Johanna C JC; Sudmant, Peter H PH; Dorajoo, Rajkumar R; Al-Shafai, Mashael Nedham MN; Bottolo, Leonardo L; Ozdemir, Erdal E; So, Hon-Cheong HC; Davies, Robert W RW; Patrice, Alexandre A; Dent, Robert R; Mangino, Massimo M; Hysi, Pirro G PG; Dechaume, Aurélie A; Huyvaert, Marlène M; Skinner, Jane J; Pigeyre, Marie M; Caiazzo, Robert R; Raverdy, Violeta V; Vaillant, Emmanuel E; Field, Sarah S; Balkau, Beverley B; Marre, Michel M; Visvikis-Siest, Sophie S; Weill, Jacques J; Poulain-Godefroy, Odile O; Jacobson, Peter P; Sjostrom, Lars L; Hammond, Christopher J CJ; Deloukas, Panos P; Sham, Pak Chung PC; McPherson, Ruth R; Lee, Jeannette J; Tai, E Shyong ES; Sladek, Robert R; Carlsson, Lena M S LM; Walley, Andrew A; Eichler, Evan E EE; Pattou, Francois F; Spector, Timothy D TD; Froguel, Philippe P
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.
Nature Genetics
Monda, Keri L KL; Chen, Gary K GK; Taylor, Kira C KC; Palmer, Cameron C; Edwards, Todd L TL; Lange, Leslie A LA; Ng, Maggie C Y MC; Adeyemo, Adebowale A AA; Allison, Matthew A MA; Bielak, Lawrence F LF; Chen, Guanjie G; Graff, Mariaelisa M; Irvin, Marguerite R MR; Rhie, Suhn K SK; Li, Guo G; Liu, Yongmei Y; Liu, Youfang Y; Lu, Yingchang Y; Nalls, Michael A MA; Sun, Yan V YV; Wojczynski, Mary K MK; Yanek, Lisa R LR; Aldrich, Melinda C MC; Ademola, Adeyinka A; Amos, Christopher I CI; Bandera, Elisa V EV; Bock, Cathryn H CH; Britton, Angela A; Broeckel, Ulrich U; Cai, Quiyin Q; Caporaso, Neil E NE; Carlson, Chris S CS; Carpten, John J; Casey, Graham G; Chen, Wei-Min WM; Chen, Fang F; Chen, Yii-Der I YD; Chiang, Charleston W K CW; Coetzee, Gerhard A GA; Demerath, Ellen E; Deming-Halverson, Sandra L SL; Driver, Ryan W RW; Dubbert, Patricia P; Feitosa, Mary F MF; Feng, Ye Y; Freedman, Barry I BI; Gillanders, Elizabeth M EM; Gottesman, Omri O; Guo, Xiuqing X; Haritunians, Talin T; Harris, Tamara T; Harris, Curtis C CC; Hennis, Anselm J M AJ; Hernandez, Dena G DG; McNeill, Lorna H LH; Howard, Timothy D TD; Howard, Barbara V BV; Howard, Virginia J VJ; Johnson, Karen C KC; Kang, Sun J SJ; Keating, Brendan J BJ; Kolb, Suzanne S; Kuller, Lewis H LH; Kutlar, Abdullah A; Langefeld, Carl D CD; Lettre, Guillaume G; Lohman, Kurt K; Lotay, Vaneet V; Lyon, Helen H; Manson, Joann E JE; Maixner, William W; Meng, Yan A YA; Monroe, Kristine R KR; Morhason-Bello, Imran I; Murphy, Adam B AB; Mychaleckyj, Josyf C JC; Nadukuru, Rajiv R; Nathanson, Katherine L KL; Nayak, Uma U; N'diaye, Amidou A; Nemesure, Barbara B; Wu, Suh-Yuh SY; Leske, M Cristina MC; Neslund-Dudas, Christine C; Neuhouser, Marian M; Nyante, Sarah S; Ochs-Balcom, Heather H; Ogunniyi, Adesola A; Ogundiran, Temidayo O TO; Ojengbede, Oladosu O; Olopade, Olufunmilayo I OI; Palmer, Julie R JR; Ruiz-Narvaez, Edward A EA; Palmer, Nicholette D ND; Press, Michael F MF; Rampersaud, Evandine E; Rasmussen-Torvik, Laura J LJ; Rodriguez-Gil, Jorge L JL; Salako, Babatunde B; Schadt, Eric E EE; Schwartz, Ann G AG; Shriner, Daniel A DA; Siscovick, David D; Smith, Shad B SB; Wassertheil-Smoller, Sylvia S; Speliotes, Elizabeth K EK; Spitz, Margaret R MR; Sucheston, Lara L; Taylor, Herman H; Tayo, Bamidele O BO; Tucker, Margaret A MA; Van Den Berg, David J DJ; Edwards, Digna R Velez DR; Wang, Zhaoming Z; Wiencke, John K JK; Winkler, Thomas W TW; Witte, John S JS; Wrensch, Margaret M; Wu, Xifeng X; Yang, James J JJ; Levin, Albert M AM; Young, Taylor R TR; Zakai, Neil A NA; Cushman, Mary M; Zanetti, Krista A KA; Zhao, Jing Hua JH; Zhao, Wei W; Zheng, Yonglan Y; Zhou, Jie J; Ziegler, Regina G RG; Zmuda, Joseph M JM; Fernandes, Jyotika K JK; Gilkeson, Gary S GS; Kamen, Diane L DL; Hunt, Kelly J KJ; Spruill, Ida J IJ; Ambrosone, Christine B CB; Ambs, Stefan S; Arnett, Donna K DK; Atwood, Larry L; Becker, Diane M DM; Berndt, Sonja I SI; Bernstein, Leslie L; Blot, William J WJ; Borecki, Ingrid B IB; Bottinger, Erwin P EP; Bowden, Donald W DW; Burke, Gregory G; Chanock, Stephen J SJ; Cooper, Richard S RS; Ding, Jingzhong J; Duggan, David D; Evans, Michele K MK; Fox, Caroline C; Garvey, W Timothy WT; Bradfield, Jonathan P JP; Hakonarson, Hakon H; Grant, Struan F A SF; Hsing, Ann A; Chu, Lisa L; Hu, Jennifer J JJ; Huo, Dezheng D; Ingles, Sue A SA; John, Esther M EM; Jordan, Joanne M JM; Kabagambe, Edmond K EK; Kardia, Sharon L R SL; Kittles, Rick A RA; Goodman, Phyllis J PJ; Klein, Eric A EA; Kolonel, Laurence N LN; Le Marchand, Loic L; Liu, Simin S; McKnight, Barbara B; Millikan, Robert C RC; Mosley, Thomas H TH; Padhukasahasram, Badri B; Williams, L Keoki LK; Patel, Sanjay R SR; Peters, Ulrike U; Pettaway, Curtis A CA; Peyser, Patricia A PA; Psaty, Bruce M BM; Redline, Susan S; Rotimi, Charles N CN; Rybicki, Benjamin A BA; Sale, Michèle M MM; Schreiner, Pamela J PJ; Signorello, Lisa B LB; Singleton, Andrew B AB; Stanford, Janet L JL; Strom, Sara S SS; Thun, Michael J MJ; Vitolins, Mara M; Zheng, Wei W; Moore, Jason H JH; Williams, Scott M SM; Ketkar, Shamika S; Zhu, Xiaofeng X; Zonderman, Alan B AB; , ; , ; , ; , ; Kooperberg, Charles C; Papanicolaou, George J GJ; Henderson, Brian E BE; Reiner, Alex P AP; Hirschhorn, Joel N JN; Loos, Ruth J F RJ; North, Kari E KE; Haiman, Christopher A CA
A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study.
Plos Genetics
Peters, Ulrike U; North, Kari E KE; Sethupathy, Praveen P; Buyske, Steve S; Haessler, Jeff J; Jiao, Shuo S; Fesinmeyer, Megan D MD; Jackson, Rebecca D RD; Kuller, Lew H LH; Rajkovic, Aleksandar A; Lim, Unhee U; Cheng, Iona I; Schumacher, Fred F; Wilkens, Lynne L; Li, Rongling R; Monda, Keri K; Ehret, Georg G; Nguyen, Khanh-Dung H KD; Cooper, Richard R; Lewis, Cora E CE; Leppert, Mark M; Irvin, Marguerite R MR; Gu, C Charles CC; Houston, Denise D; Buzkova, Petra P; Ritchie, Marylyn M; Matise, Tara C TC; Le Marchand, Loic L; Hindorff, Lucia A LA; Crawford, Dana C DC; Haiman, Christopher A CA; Kooperberg, Charles C
Absence of association between specific common variants of the obesity-related FTO gene and psychological and behavioral eating disorder phenotypes.
American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
Jonassaint, Charles R CR; Szatkiewicz, Jin Peng JP; Bulik, Cynthia M CM; Thornton, Laura M LM; Bloss, Cinnamon C; Berrettini, Wade H WH; Kaye, Walter H WH; Bergen, Andrew W AW; Magistretti, Pierre P; Strober, Michael M; Keel, Pamela K PK; Brandt, Harry H; Crawford, Steve S; Crow, Scott S; Fichter, Manfred M MM; Goldman, David D; Halmi, Katherine A KA; Johnson, Craig C; Kaplan, Allan S AS; Klump, Kelly L KL; La Via, Maria M; Mitchell, James E JE; Rotondo, Alessandro A; Treasure, Janet J; Woodside, D Blake DB
Fine mapping of the association with obesity at the FTO locus in African-derived populations.
Human Molecular Genetics
Hassanein, Mohamed T MT; Lyon, Helen N HN; Nguyen, Thutrang T TT; Akylbekova, Ermeg L EL; Waters, Kevin K; Lettre, Guillaume G; Tayo, Bamidele B; Forrester, Terrence T; Sarpong, Daniel F DF; Stram, Dan O DO; Butler, Johannah L JL; Wilks, Rainford R; Liu, Jiankang J; Le Marchand, Loic L; Kolonel, Laurence N LN; Zhu, Xiaofeng X; Henderson, Brian B; Cooper, Richard R; McKenzie, Colin C; Taylor, Herman A HA; Haiman, Christopher A CA; Hirschhorn, Joel N JN