FTO c.46-12281G>T

Variant ID: 16-53831771-G-T

NM_001080432.2(FTO):c.46-12281G>T

This variant was identified in 14 publications

View GRCh38 version.




Publications:


Identification and Association of Single Nucleotide Polymorphisms of the FTO Gene with Indicators of Overweight and Obesity in a Young Mexican Population.

Genes
Chama-Avilés, Alonso A; Flores-Viveros, Karla Lucero KL; Cabrera-Ayala, Jorge Alberto JA; Aguilar-Galarza, Adriana A; García-Muñoz, Willebaldo W; Haddad-Talancón, Lorenza L; de Lourdes Anzures-Cortés, Ma M; Velázquez-Sánchez, Claudia C; Chávez-Servín, Jorge Luis JL; Anaya-Loyola, Miriam Aracely MA; García-Gasca, Teresa T; Rodríguez-García, Víctor Manuel VM; Moreno-Celis, Ulisses U
Publication Date: 2023-01-06

Variant appearance in text: rs9922619
PubMed Link: 36672899
Variant Present in the following documents:
  • Main text
  • genes-14-00159.pdf
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A new method for exploring gene-gene and gene-environment interactions in GWAS with tree ensemble methods and SHAP values.

Bmc Bioinformatics
Johnsen, Pål V PV; Riemer-Sørensen, Signe S; DeWan, Andrew Thomas AT; Cahill, Megan E ME; Langaas, Mette M
Publication Date: 2021-05-04

Variant appearance in text: rs9922619
PubMed Link: 33947323
Variant Present in the following documents:
  • Main text
View BVdb publication page



Replication of FTO Gene associated with lean mass in a Meta-Analysis of Genome-Wide Association Studies.

Scientific Reports
Ran, Shu S; Jiang, Zi-Xuan ZX; He, Xiao X; Liu, Yu Y; Zhang, Yu-Xue YX; Zhang, Lei L; Pei, Yu-Fang YF; Zhang, Meng M; Hai, Rong R; Gu, Gui-Shan GS; Liu, Bao-Lin BL; Tian, Qing Q; Zhang, Yong-Hong YH; Wang, Jing-Yu JY; Deng, Hong-Wen HW
Publication Date: 2020-03-19

Variant appearance in text: rs9922619
PubMed Link: 32193455
Variant Present in the following documents:
  • Main text
  • 41598_2020_Article_61406.pdf
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Functional genomic characterization of the FTO locus in African Americans.

Physiological Genomics
Gill, Richard R; Stratigopoulos, George G; Lee, Joseph H JH; Leibel, Rudolph L RL
Publication Date: 2019-11-01

Variant appearance in text: rs9922619
PubMed Link: 31530225
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-Wide Study of Subcutaneous and Visceral Adipose Tissue Reveals Novel Sex-Specific Adiposity Loci in Mexican Americans.

Obesity (Silver Spring, Md.)
Gao, Chuan C; Langefeld, Carl D CD; Ziegler, Julie T JT; Taylor, Kent D KD; Norris, Jill M JM; Chen, Yii-Der I YI; Hellwege, Jacklyn N JN; Guo, Xiuqing X; Allison, Matthew A MA; Speliotes, Elizabeth K EK; Rotter, Jerome I JI; Bowden, Donald W DW; Wagenknecht, Lynne E LE; Palmer, Nicholette D ND
Publication Date: 2018-01

Variant appearance in text: rs9922619
PubMed Link: 29178545
Variant Present in the following documents:
  • Main text
  • nihms915553.pdf
View BVdb publication page



Conditional analysis of multiple quantitative traits based on marginal GWAS summary statistics.

Genetic Epidemiology
Deng, Yangqing Y; Pan, Wei W
Publication Date: 2017-07

Variant appearance in text: rs9922619
PubMed Link: 28464407
Variant Present in the following documents:
  • Main text
View BVdb publication page



Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer.

Cancer Epidemiology
Yang, Baiyu B; Thrift, Aaron P AP; Figueiredo, Jane C JC; Jenkins, Mark A MA; Schumacher, Fredrick R FR; Conti, David V DV; Lin, Yi Y; Win, Aung Ko AK; Limburg, Paul J PJ; Berndt, Sonja I SI; Brenner, Hermann H; Chan, Andrew T AT; Chang-Claude, Jenny J; Hoffmeister, Michael M; Hudson, Thomas J TJ; Marchand, Loïc Le LL; Newcomb, Polly A PA; Slattery, Martha L ML; White, Emily E; Peters, Ulrike U; Casey, Graham G; Campbell, Peter T PT
Publication Date: 2016-10

Variant appearance in text: rs9922619
PubMed Link: 27449576
Variant Present in the following documents:
  • Main text
View BVdb publication page



Detection and interpretation of shared genetic influences on 42 human traits.

Nature Genetics
Pickrell, Joseph K JK; Berisa, Tomaz T; Liu, Jimmy Z JZ; Ségurel, Laure L; Tung, Joyce Y JY; Hinds, David A DA
Publication Date: 2016-07

Variant appearance in text: rs9922619
PubMed Link: 27182965
Variant Present in the following documents:
  • NIHMS780506-supplement-7.pdf
  • NIHMS780506-supplement-3.pdf
View BVdb publication page



Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat.

International Journal Of Obesity (2005)
Sung, Y J YJ; Pérusse, L L; Sarzynski, M A MA; Fornage, M M; Sidney, S S; Sternfeld, B B; Rice, T T; Terry, J G JG; Jacobs, D R DR; Katzmarzyk, P P; Curran, J E JE; Jeffrey Carr, J J; Blangero, J J; Ghosh, S S; Després, J-P JP; Rankinen, T T; Rao, D C DC; Bouchard, C C
Publication Date: 2016-04

Variant appearance in text: rs9922619
PubMed Link: 26480920
Variant Present in the following documents:
  • Main text
  • nihms729351.pdf
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Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index.

Frontiers In Genetics
Cronin, Robert M RM; Field, Julie R JR; Bradford, Yuki Y; Shaffer, Christian M CM; Carroll, Robert J RJ; Mosley, Jonathan D JD; Bastarache, Lisa L; Edwards, Todd L TL; Hebbring, Scott J SJ; Lin, Simon S; Hindorff, Lucia A LA; Crane, Paul K PK; Pendergrass, Sarah A SA; Ritchie, Marylyn D MD; Crawford, Dana C DC; Pathak, Jyotishman J; Bielinski, Suzette J SJ; Carrell, David S DS; Crosslin, David R DR; Ledbetter, David H DH; Carey, David J DJ; Tromp, Gerard G; Williams, Marc S MS; Larson, Eric B EB; Jarvik, Gail P GP; Peissig, Peggy L PL; Brilliant, Murray H MH; McCarty, Catherine A CA; Chute, Christopher G CG; Kullo, Iftikhar J IJ; Bottinger, Erwin E; Chisholm, Rex R; Smith, Maureen E ME; Roden, Dan M DM; Denny, Joshua C JC
Publication Date: 2014

Variant appearance in text: rs9922619
PubMed Link: 25177340
Variant Present in the following documents:
  • Main text
  • fgene-05-00250.pdf
View BVdb publication page



Low copy number of the salivary amylase gene predisposes to obesity.

Nature Genetics
Falchi, Mario M; El-Sayed Moustafa, Julia Sarah JS; Takousis, Petros P; Pesce, Francesco F; Bonnefond, Amélie A; Andersson-Assarsson, Johanna C JC; Sudmant, Peter H PH; Dorajoo, Rajkumar R; Al-Shafai, Mashael Nedham MN; Bottolo, Leonardo L; Ozdemir, Erdal E; So, Hon-Cheong HC; Davies, Robert W RW; Patrice, Alexandre A; Dent, Robert R; Mangino, Massimo M; Hysi, Pirro G PG; Dechaume, Aurélie A; Huyvaert, Marlène M; Skinner, Jane J; Pigeyre, Marie M; Caiazzo, Robert R; Raverdy, Violeta V; Vaillant, Emmanuel E; Field, Sarah S; Balkau, Beverley B; Marre, Michel M; Visvikis-Siest, Sophie S; Weill, Jacques J; Poulain-Godefroy, Odile O; Jacobson, Peter P; Sjostrom, Lars L; Hammond, Christopher J CJ; Deloukas, Panos P; Sham, Pak Chung PC; McPherson, Ruth R; Lee, Jeannette J; Tai, E Shyong ES; Sladek, Robert R; Carlsson, Lena M S LM; Walley, Andrew A; Eichler, Evan E EE; Pattou, Francois F; Spector, Timothy D TD; Froguel, Philippe P
Publication Date: 2014-05

Variant appearance in text: rs9922619
PubMed Link: 24686848
Variant Present in the following documents:
  • NIHMS57335-supplement-1.pdf
View BVdb publication page



Determination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children.

International Journal Of Obesity (2005)
Sällman Almén, M M; Rask-Andersen, M M; Jacobsson, J A JA; Ameur, A A; Kalnina, I I; Moschonis, G G; Juhlin, S S; Bringeland, N N; Hedberg, L A LA; Ignatovica, V V; Chrousos, G P GP; Manios, Y Y; Klovins, J J; Marcus, C C; Gyllensten, U U; Fredriksson, R R; Schiöth, H B HB
Publication Date: 2013-03

Variant appearance in text: rs9922619
PubMed Link: 22531089
Variant Present in the following documents:
  • Main text
  • ijo201257a.pdf
View BVdb publication page



Variations in the FTO gene are associated with severe obesity in the Japanese.

Journal Of Human Genetics
Hotta, Kikuko K; Nakata, Yoshio Y; Matsuo, Tomoaki T; Kamohara, Seika S; Kotani, Kazuaki K; Komatsu, Ryoya R; Itoh, Naoto N; Mineo, Ikuo I; Wada, Jun J; Masuzaki, Hiroaki H; Yoneda, Masato M; Nakajima, Atsushi A; Miyazaki, Shigeru S; Tokunaga, Katsuto K; Kawamoto, Manabu M; Funahashi, Tohru T; Hamaguchi, Kazuyuki K; Yamada, Kentaro K; Hanafusa, Toshiaki T; Oikawa, Shinichi S; Yoshimatsu, Hironobu H; Nakao, Kazuwa K; Sakata, Toshiie T; Matsuzawa, Yuji Y; Tanaka, Kiyoji K; Kamatani, Naoyuki N; Nakamura, Yusuke Y
Publication Date: 2008

Variant appearance in text: rs9922619
PubMed Link: 18379722
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.

Plos Genetics
Scuteri, Angelo A; Sanna, Serena S; Chen, Wei-Min WM; Uda, Manuela M; Albai, Giuseppe G; Strait, James J; Najjar, Samer S; Nagaraja, Ramaiah R; Orrú, Marco M; Usala, Gianluca G; Dei, Mariano M; Lai, Sandra S; Maschio, Andrea A; Busonero, Fabio F; Mulas, Antonella A; Ehret, Georg B GB; Fink, Ashley A AA; Weder, Alan B AB; Cooper, Richard S RS; Galan, Pilar P; Chakravarti, Aravinda A; Schlessinger, David D; Cao, Antonio A; Lakatta, Edward E; Abecasis, Gonçalo R GR
Publication Date: 2007-07

Variant appearance in text: rs9922619
PubMed Link: 17658951
Variant Present in the following documents:
  • pgen.0030115.pdf
View BVdb publication page