Genetic Variants of HNF4A, WFS1, DUSP9, FTO, and ZFAND6 Genes Are Associated with Prediabetes Susceptibility and Inflammatory Markers in the Saudi Arabian Population.
Genes
Binjawhar, Dalal N DN; Ansari, Mohammed G A MGA; Sabico, Shaun S; Hussain, Syed Danish SD; Alenad, Amal M AM; Alokail, Majed S MS; Al-Masri, Abeer A AA; Al-Daghri, Nasser M NM
Identification and Association of Single Nucleotide Polymorphisms of the FTO Gene with Indicators of Overweight and Obesity in a Young Mexican Population.
Genes
Chama-Avilés, Alonso A; Flores-Viveros, Karla Lucero KL; Cabrera-Ayala, Jorge Alberto JA; Aguilar-Galarza, Adriana A; García-Muñoz, Willebaldo W; Haddad-Talancón, Lorenza L; de Lourdes Anzures-Cortés, Ma M; Velázquez-Sánchez, Claudia C; Chávez-Servín, Jorge Luis JL; Anaya-Loyola, Miriam Aracely MA; García-Gasca, Teresa T; Rodríguez-García, Víctor Manuel VM; Moreno-Celis, Ulisses U
Single Nucleotide Polymorphisms in Close Proximity to the Fibroblast Growth Factor 21 (FGF21) Gene Found to Be Associated with Sugar Intake in a Swedish Population.
Nutrients
Janzi, Suzanne S; González-Padilla, Esther E; Najafi, Kevin K; Ramne, Stina S; Ahlqvist, Emma E; Borné, Yan Y; Sonestedt, Emily E
All thresholds of maternal hyperglycaemia from the WHO 2013 criteria for gestational diabetes identify women with a higher genetic risk for type 2 diabetes.
Wellcome Open Research
Hughes, Alice E AE; Hayes, M Geoffrey MG; Egan, Aoife M AM; Patel, Kashyap A KA; Scholtens, Denise M DM; Lowe, Lynn P LP; Lowe, William L WL; Dunne, Fidelma P FP; Hattersley, Andrew T AT; Freathy, Rachel M RM
Association among Body Mass Index, Genetic Variants of FTO, and Thyroid Cancer Risk: A Hospital-Based Case-Control Study of the Cancer Screenee Cohort in Korea.
Genetic factors and risk of type 2 diabetes among women with a history of gestational diabetes: findings from two independent populations.
Bmj Open Diabetes Research & Care
Li, Mengying M; Rahman, Mohammad L ML; Wu, Jing J; Ding, Ming M; Chavarro, Jorge E JE; Lin, Yuan Y; Ley, Sylvia H SH; Bao, Wei W; Grunnet, Louise G LG; Hinkle, Stefanie N SN; Thuesen, Anne Cathrine B ACB; Yeung, Edwina E; Gore-Langton, Robert E RE; Sherman, Seth S; Hjort, Line L; Kampmann, Freja Bach FB; Bjerregaard, Anne Ahrendt AA; Damm, Peter P; Tekola-Ayele, Fasil F; Liu, Aiyi A; Mills, James L JL; Vaag, Allan A; Olsen, Sjurdur F SF; Hu, Frank B FB; Zhang, Cuilin C
New insight into human sweet taste: a genome-wide association study of the perception and intake of sweet substances.
The American Journal Of Clinical Nutrition
Hwang, Liang-Dar LD; Lin, Cailu C; Gharahkhani, Puya P; Cuellar-Partida, Gabriel G; Ong, Jue-Sheng JS; An, Jiyuan J; Gordon, Scott D SD; Zhu, Gu G; MacGregor, Stuart S; Lawlor, Deborah A DA; Breslin, Paul A S PAS; Wright, Margaret J MJ; Martin, Nicholas G NG; Reed, Danielle R DR
Blood-based analysis of type-2 diabetes mellitus susceptibility genes identifies specific transcript variants with deregulated expression and association with disease risk.
Scientific Reports
Christodoulou, Maria-Ioanna MI; Avgeris, Margaritis M; Kokkinopoulou, Ioanna I; Maratou, Eirini E; Mitrou, Panayota P; Kontos, Christos K CK; Pappas, Efthimios E; Boutati, Eleni E; Scorilas, Andreas A; Fragoulis, Emmanuel G EG
The genetic underpinnings of variation in ages at menarche and natural menopause among women from the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) Study: A trans-ethnic meta-analysis.
Plos One
Fernández-Rhodes, Lindsay L; Malinowski, Jennifer R JR; Wang, Yujie Y; Tao, Ran R; Pankratz, Nathan N; Jeff, Janina M JM; Yoneyama, Sachiko S; Carty, Cara L CL; Setiawan, V Wendy VW; Le Marchand, Loic L; Haiman, Christopher C; Corbett, Steven S; Demerath, Ellen E; Heiss, Gerardo G; Gross, Myron M; Buzkova, Petra P; Crawford, Dana C DC; Hunt, Steven C SC; Rao, D C DC; Schwander, Karen K; Chakravarti, Aravinda A; Gottesman, Omri O; Abul-Husn, Noura S NS; Bottinger, Erwin P EP; Loos, Ruth J F RJF; Raffel, Leslie J LJ; Yao, Jie J; Guo, Xiuqing X; Bielinski, Suzette J SJ; Rotter, Jerome I JI; Vaidya, Dhananjay D; Chen, Yii-Der Ida YI; Castañeda, Sheila F SF; Daviglus, Martha M; Kaplan, Robert R; Talavera, Gregory A GA; Ryckman, Kelli K KK; Peters, Ulrike U; Ambite, Jose Luis JL; Buyske, Steven S; Hindorff, Lucia L; Kooperberg, Charles C; Matise, Tara T; Franceschini, Nora N; North, Kari E KE
Influence of genetic ancestry and socioeconomic status on type 2 diabetes in the diverse Colombian populations of Chocó and Antioquia.
Scientific Reports
Chande, Aroon T AT; Rowell, Jessica J; Rishishwar, Lavanya L; Conley, Andrew B AB; Norris, Emily T ET; Valderrama-Aguirre, Augusto A; Medina-Rivas, Miguel A MA; Jordan, I King IK
Association Study with 77 SNPs Confirms the Robust Role for the rs10830963/G of MTNR1B Variant and Identifies Two Novel Associations in Gestational Diabetes Mellitus Development.
Plos One
Rosta, Klara K; Al-Aissa, Zahra Z; Hadarits, Orsolya O; Harreiter, Jürgen J; Nádasdi, Ákos Á; Kelemen, Fanni F; Bancher-Todesca, Dagmar D; Komlósi, Zsolt Z; Németh, László L; Rigó, János J; Sziller, István I; Somogyi, Anikó A; Kautzky-Willer, Alexandra A; Firneisz, Gábor G
Type 2 Diabetes Risk Allele Loci in the Qatari Population.
Plos One
O'Beirne, Sarah L SL; Salit, Jacqueline J; Rodriguez-Flores, Juan L JL; Staudt, Michelle R MR; Abi Khalil, Charbel C; Fakhro, Khalid A KA; Robay, Amal A; Ramstetter, Monica D MD; Al-Azwani, Iman K IK; Malek, Joel A JA; Zirie, Mahmoud M; Jayyousi, Amin A; Badii, Ramin R; Al-Nabet Al-Marri, Ajayeb A; Chiuchiolo, Maria J MJ; Al-Shakaki, Alya A; Chidiac, Omar O; Gharbiah, Maey M; Bener, Abdulbari A; Stadler, Dora D; Hackett, Neil R NR; Mezey, Jason G JG; Crystal, Ronald G RG
Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR).
Biodata Mining
De, Rishika R; Verma, Shefali S SS; Drenos, Fotios F; Holzinger, Emily R ER; Holmes, Michael V MV; Hall, Molly A MA; Crosslin, David R DR; Carrell, David S DS; Hakonarson, Hakon H; Jarvik, Gail G; Larson, Eric E; Pacheco, Jennifer A JA; Rasmussen-Torvik, Laura J LJ; Moore, Carrie B CB; Asselbergs, Folkert W FW; Moore, Jason H JH; Ritchie, Marylyn D MD; Keating, Brendan J BJ; Gilbert-Diamond, Diane D
Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.
Plos Genetics
Ng, Maggie C Y MC; Shriner, Daniel D; Chen, Brian H BH; Li, Jiang J; Chen, Wei-Min WM; Guo, Xiuqing X; Liu, Jiankang J; Bielinski, Suzette J SJ; Yanek, Lisa R LR; Nalls, Michael A MA; Comeau, Mary E ME; Rasmussen-Torvik, Laura J LJ; Jensen, Richard A RA; Evans, Daniel S DS; Sun, Yan V YV; An, Ping P; Patel, Sanjay R SR; Lu, Yingchang Y; Long, Jirong J; Armstrong, Loren L LL; Wagenknecht, Lynne L; Yang, Lingyao L; Snively, Beverly M BM; Palmer, Nicholette D ND; Mudgal, Poorva P; Langefeld, Carl D CD; Keene, Keith L KL; Freedman, Barry I BI; Mychaleckyj, Josyf C JC; Nayak, Uma U; Raffel, Leslie J LJ; Goodarzi, Mark O MO; Chen, Y-D Ida YD; Taylor, Herman A HA; Correa, Adolfo A; Sims, Mario M; Couper, David D; Pankow, James S JS; Boerwinkle, Eric E; Adeyemo, Adebowale A; Doumatey, Ayo A; Chen, Guanjie G; Mathias, Rasika A RA; Vaidya, Dhananjay D; Singleton, Andrew B AB; Zonderman, Alan B AB; Igo, Robert P RP; Sedor, John R JR; , ; Kabagambe, Edmond K EK; Siscovick, David S DS; McKnight, Barbara B; Rice, Kenneth K; Liu, Yongmei Y; Hsueh, Wen-Chi WC; Zhao, Wei W; Bielak, Lawrence F LF; Kraja, Aldi A; Province, Michael A MA; Bottinger, Erwin P EP; Gottesman, Omri O; Cai, Qiuyin Q; Zheng, Wei W; Blot, William J WJ; Lowe, William L WL; Pacheco, Jennifer A JA; Crawford, Dana C DC; , ; , ; Grundberg, Elin E; , ; Rich, Stephen S SS; Hayes, M Geoffrey MG; Shu, Xiao-Ou XO; Loos, Ruth J F RJ; Borecki, Ingrid B IB; Peyser, Patricia A PA; Cummings, Steven R SR; Psaty, Bruce M BM; Fornage, Myriam M; Iyengar, Sudha K SK; Evans, Michele K MK; Becker, Diane M DM; Kao, W H Linda WH; Wilson, James G JG; Rotter, Jerome I JI; Sale, Michèle M MM; Liu, Simin S; Rotimi, Charles N CN; Bowden, Donald W DW; ,
Low copy number of the salivary amylase gene predisposes to obesity.
Nature Genetics
Falchi, Mario M; El-Sayed Moustafa, Julia Sarah JS; Takousis, Petros P; Pesce, Francesco F; Bonnefond, Amélie A; Andersson-Assarsson, Johanna C JC; Sudmant, Peter H PH; Dorajoo, Rajkumar R; Al-Shafai, Mashael Nedham MN; Bottolo, Leonardo L; Ozdemir, Erdal E; So, Hon-Cheong HC; Davies, Robert W RW; Patrice, Alexandre A; Dent, Robert R; Mangino, Massimo M; Hysi, Pirro G PG; Dechaume, Aurélie A; Huyvaert, Marlène M; Skinner, Jane J; Pigeyre, Marie M; Caiazzo, Robert R; Raverdy, Violeta V; Vaillant, Emmanuel E; Field, Sarah S; Balkau, Beverley B; Marre, Michel M; Visvikis-Siest, Sophie S; Weill, Jacques J; Poulain-Godefroy, Odile O; Jacobson, Peter P; Sjostrom, Lars L; Hammond, Christopher J CJ; Deloukas, Panos P; Sham, Pak Chung PC; McPherson, Ruth R; Lee, Jeannette J; Tai, E Shyong ES; Sladek, Robert R; Carlsson, Lena M S LM; Walley, Andrew A; Eichler, Evan E EE; Pattou, Francois F; Spector, Timothy D TD; Froguel, Philippe P
RNAi screening in primary human hepatocytes of genes implicated in genome-wide association studies for roles in type 2 diabetes identifies roles for CAMK1D and CDKAL1, among others, in hepatic glucose regulation.
Plos One
Haney, Steven S; Zhao, Juan J; Tiwari, Shiwani S; Eng, Kurt K; Guey, Lin T LT; Tien, Eric E
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
Nature Genetics
Morris, Andrew P AP; Voight, Benjamin F BF; Teslovich, Tanya M TM; Ferreira, Teresa T; Segrè, Ayellet V AV; Steinthorsdottir, Valgerdur V; Strawbridge, Rona J RJ; Khan, Hassan H; Grallert, Harald H; Mahajan, Anubha A; Prokopenko, Inga I; Kang, Hyun Min HM; Dina, Christian C; Esko, Tonu T; Fraser, Ross M RM; Kanoni, Stavroula S; Kumar, Ashish A; Lagou, Vasiliki V; Langenberg, Claudia C; Luan, Jian'an J; Lindgren, Cecilia M CM; Müller-Nurasyid, Martina M; Pechlivanis, Sonali S; Rayner, N William NW; Scott, Laura J LJ; Wiltshire, Steven S; Yengo, Loic L; Kinnunen, Leena L; Rossin, Elizabeth J EJ; Raychaudhuri, Soumya S; Johnson, Andrew D AD; Dimas, Antigone S AS; Loos, Ruth J F RJ; Vedantam, Sailaja S; Chen, Han H; Florez, Jose C JC; Fox, Caroline C; Liu, Ching-Ti CT; Rybin, Denis D; Couper, David J DJ; Kao, Wen Hong L WH; Li, Man M; Cornelis, Marilyn C MC; Kraft, Peter P; Sun, Qi Q; van Dam, Rob M RM; Stringham, Heather M HM; Chines, Peter S PS; Fischer, Krista K; Fontanillas, Pierre P; Holmen, Oddgeir L OL; Hunt, Sarah E SE; Jackson, Anne U AU; Kong, Augustine A; Lawrence, Robert R; Meyer, Julia J; Perry, John R B JR; Platou, Carl G P CG; Potter, Simon S; Rehnberg, Emil E; Robertson, Neil N; Sivapalaratnam, Suthesh S; Stančáková, Alena A; Stirrups, Kathleen K; Thorleifsson, Gudmar G; Tikkanen, Emmi E; Wood, Andrew R AR; Almgren, Peter P; Atalay, Mustafa M; Benediktsson, Rafn R; Bonnycastle, Lori L LL; Burtt, Noël N; Carey, Jason J; Charpentier, Guillaume G; Crenshaw, Andrew T AT; Doney, Alex S F AS; Dorkhan, Mozhgan M; Edkins, Sarah S; Emilsson, Valur V; Eury, Elodie E; Forsen, Tom T; Gertow, Karl K; Gigante, Bruna B; Grant, George B GB; Groves, Christopher J CJ; Guiducci, Candace C; Herder, Christian C; Hreidarsson, Astradur B AB; Hui, Jennie J; James, Alan A; Jonsson, Anna A; Rathmann, Wolfgang W; Klopp, Norman N; Kravic, Jasmina J; Krjutškov, Kaarel K; Langford, Cordelia C; Leander, Karin K; Lindholm, Eero E; Lobbens, Stéphane S; Männistö, Satu S; Mirza, Ghazala G; Mühleisen, Thomas W TW; Musk, Bill B; Parkin, Melissa M; Rallidis, Loukianos L; Saramies, Jouko J; Sennblad, Bengt B; Shah, Sonia S; Sigurðsson, Gunnar G; Silveira, Angela A; Steinbach, Gerald G; Thorand, Barbara B; Trakalo, Joseph J; Veglia, Fabrizio F; Wennauer, Roman R; Winckler, Wendy W; Zabaneh, Delilah D; Campbell, Harry H; van Duijn, Cornelia C; Uitterlinden, Andre G AG; Hofman, Albert A; Sijbrands, Eric E; Abecasis, Goncalo R GR; Owen, Katharine R KR; Zeggini, Eleftheria E; Trip, Mieke D MD; Forouhi, Nita G NG; Syvänen, Ann-Christine AC; Eriksson, Johan G JG; Peltonen, Leena L; Nöthen, Markus M MM; Balkau, Beverley B; Palmer, Colin N A CN; Lyssenko, Valeriya V; Tuomi, Tiinamaija T; Isomaa, Bo B; Hunter, David J DJ; Qi, Lu L; , ; , ; , ; , ; , ; Shuldiner, Alan R AR; Roden, Michael M; Barroso, Ines I; Wilsgaard, Tom T; Beilby, John J; Hovingh, Kees K; Price, Jackie F JF; Wilson, James F JF; Rauramaa, Rainer R; Lakka, Timo A TA; Lind, Lars L; Dedoussis, George G; Njølstad, Inger I; Pedersen, Nancy L NL; Khaw, Kay-Tee KT; Wareham, Nicholas J NJ; Keinanen-Kiukaanniemi, Sirkka M SM; Saaristo, Timo E TE; Korpi-Hyövälti, Eeva E; Saltevo, Juha J; Laakso, Markku M; Kuusisto, Johanna J; Metspalu, Andres A; Collins, Francis S FS; Mohlke, Karen L KL; Bergman, Richard N RN; Tuomilehto, Jaakko J; Boehm, Bernhard O BO; Gieger, Christian C; Hveem, Kristian K; Cauchi, Stephane S; Froguel, Philippe P; Baldassarre, Damiano D; Tremoli, Elena E; Humphries, Steve E SE; Saleheen, Danish D; Danesh, John J; Ingelsson, Erik E; Ripatti, Samuli S; Salomaa, Veikko V; Erbel, Raimund R; Jöckel, Karl-Heinz KH; Moebus, Susanne S; Peters, Annette A; Illig, Thomas T; de Faire, Ulf U; Hamsten, Anders A; Morris, Andrew D AD; Donnelly, Peter J PJ; Frayling, Timothy M TM; Hattersley, Andrew T AT; Boerwinkle, Eric E; Melander, Olle O; Kathiresan, Sekar S; Nilsson, Peter M PM; Deloukas, Panos P; Thorsteinsdottir, Unnur U; Groop, Leif C LC; Stefansson, Kari K; Hu, Frank F; Pankow, James S JS; Dupuis, Josée J; Meigs, James B JB; Altshuler, David D; Boehnke, Michael M; McCarthy, Mark I MI; ,
A latent variable partial least squares path modeling approach to regional association and polygenic effect with applications to a human obesity study.
Plos One
Xue, Fuzhong F; Li, Shengxu S; Luan, Jian'an J; Yuan, Zhongshang Z; Luben, Robert N RN; Khaw, Kay-Tee KT; Wareham, Nicholas J NJ; Loos, Ruth J F RJ; Zhao, Jing Hua JH
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
American Journal Of Human Genetics
Saxena, Richa R; Elbers, Clara C CC; Guo, Yiran Y; Peter, Inga I; Gaunt, Tom R TR; Mega, Jessica L JL; Lanktree, Matthew B MB; Tare, Archana A; Castillo, Berta Almoguera BA; Li, Yun R YR; Johnson, Toby T; Bruinenberg, Marcel M; Gilbert-Diamond, Diane D; Rajagopalan, Ramakrishnan R; Voight, Benjamin F BF; Balasubramanyam, Ashok A; Barnard, John J; Bauer, Florianne F; Baumert, Jens J; Bhangale, Tushar T; Böhm, Bernhard O BO; Braund, Peter S PS; Burton, Paul R PR; Chandrupatla, Hareesh R HR; Clarke, Robert R; Cooper-DeHoff, Rhonda M RM; Crook, Errol D ED; Davey-Smith, George G; Day, Ian N IN; de Boer, Anthonius A; de Groot, Mark C H MC; Drenos, Fotios F; Ferguson, Jane J; Fox, Caroline S CS; Furlong, Clement E CE; Gibson, Quince Q; Gieger, Christian C; Gilhuijs-Pederson, Lisa A LA; Glessner, Joseph T JT; Goel, Anuj A; Gong, Yan Y; Grant, Struan F A SF; Grobbee, Diederick E DE; Hastie, Claire C; Humphries, Steve E SE; Kim, Cecilia E CE; Kivimaki, Mika M; Kleber, Marcus M; Meisinger, Christa C; Kumari, Meena M; Langaee, Taimour Y TY; Lawlor, Debbie A DA; Li, Mingyao M; Lobmeyer, Maximilian T MT; Maitland-van der Zee, Anke-Hilse AH; Meijs, Matthijs F L MF; Molony, Cliona M CM; Morrow, David A DA; Murugesan, Gurunathan G; Musani, Solomon K SK; Nelson, Christopher P CP; Newhouse, Stephen J SJ; O'Connell, Jeffery R JR; Padmanabhan, Sandosh S; Palmen, Jutta J; Patel, Sanjey R SR; Pepine, Carl J CJ; Pettinger, Mary M; Price, Thomas S TS; Rafelt, Suzanne S; Ranchalis, Jane J; Rasheed, Asif A; Rosenthal, Elisabeth E; Ruczinski, Ingo I; Shah, Sonia S; Shen, Haiqing H; Silbernagel, Günther G; Smith, Erin N EN; Spijkerman, Annemieke W M AW; Stanton, Alice A; Steffes, Michael W MW; Thorand, Barbara B; Trip, Mieke M; van der Harst, Pim P; van der A, Daphne L DL; van Iperen, Erik P A EP; van Setten, Jessica J; van Vliet-Ostaptchouk, Jana V JV; Verweij, Niek N; Wolffenbuttel, Bruce H R BH; Young, Taylor T; Zafarmand, M Hadi MH; Zmuda, Joseph M JM; , ; , ; Boehnke, Michael M; Altshuler, David D; McCarthy, Mark M; Kao, W H Linda WH; Pankow, James S JS; Cappola, Thomas P TP; Sever, Peter P; Poulter, Neil N; Caulfield, Mark M; Dominiczak, Anna A; Shields, Denis C DC; Bhatt, Deepak L DL; Bhatt, Deepak D; Zhang, Li L; Curtis, Sean P SP; Danesh, John J; Casas, Juan P JP; van der Schouw, Yvonne T YT; Onland-Moret, N Charlotte NC; Doevendans, Pieter A PA; Dorn, Gerald W GW; Farrall, Martin M; FitzGerald, Garret A GA; Hamsten, Anders A; Hegele, Robert R; Hingorani, Aroon D AD; Hofker, Marten H MH; Huggins, Gordon S GS; Illig, Thomas T; Jarvik, Gail P GP; Johnson, Julie A JA; Klungel, Olaf H OH; Knowler, William C WC; Koenig, Wolfgang W; März, Winfried W; Meigs, James B JB; Melander, Olle O; Munroe, Patricia B PB; Mitchell, Braxton D BD; Bielinski, Susan J SJ; Rader, Daniel J DJ; Reilly, Muredach P MP; Rich, Stephen S SS; Rotter, Jerome I JI; Saleheen, Danish D; Samani, Nilesh J NJ; Schadt, Eric E EE; Shuldiner, Alan R AR; Silverstein, Roy R; Kottke-Marchant, Kandice K; Talmud, Philippa J PJ; Watkins, Hugh H; Asselbergs, Folkert W FW; Asselbergs, Folkert F; de Bakker, Paul I W PI; McCaffery, Jeanne J; Wijmenga, Cisca C; Sabatine, Marc S MS; Wilson, James G JG; Reiner, Alex A; Bowden, Donald W DW; Hakonarson, Hakon H; Siscovick, David S DS; Keating, Brendan J BJ