FTO c.123+6041A>G

Variant ID: 16-53850170-A-G

NM_001080432.2(FTO):c.123+6041A>G

This variant was identified in 10 publications

View GRCh38 version.




Publications:


Identification of epistatic interactions between the human RNA demethylases FTO and ALKBH5 with gene set enrichment analysis informed by differential methylation.

Bmc Proceedings
Piette, Elizabeth R ER; Moore, Jason H JH
Publication Date: 2018

Variant appearance in text: rs1421090
PubMed Link: 30275901
Variant Present in the following documents:
  • Main text
  • 12919_2018_Article_122.pdf
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Signatures of natural selection at the FTO (fat mass and obesity associated) locus in human populations.

Plos One
Liu, Xuanshi X; Weidle, Kerstin K; Schröck, Kristin K; Tönjes, Anke A; Schleinitz, Dorit D; Breitfeld, Jana J; Stumvoll, Michael M; Böttcher, Yvonne Y; Schöneberg, Torsten T; Kovacs, Peter P
Publication Date: 2015

Variant appearance in text: rs1421090
PubMed Link: 25647475
Variant Present in the following documents:
  • Main text
  • pone.0117093.pdf
View BVdb publication page



Low copy number of the salivary amylase gene predisposes to obesity.

Nature Genetics
Falchi, Mario M; El-Sayed Moustafa, Julia Sarah JS; Takousis, Petros P; Pesce, Francesco F; Bonnefond, Amélie A; Andersson-Assarsson, Johanna C JC; Sudmant, Peter H PH; Dorajoo, Rajkumar R; Al-Shafai, Mashael Nedham MN; Bottolo, Leonardo L; Ozdemir, Erdal E; So, Hon-Cheong HC; Davies, Robert W RW; Patrice, Alexandre A; Dent, Robert R; Mangino, Massimo M; Hysi, Pirro G PG; Dechaume, Aurélie A; Huyvaert, Marlène M; Skinner, Jane J; Pigeyre, Marie M; Caiazzo, Robert R; Raverdy, Violeta V; Vaillant, Emmanuel E; Field, Sarah S; Balkau, Beverley B; Marre, Michel M; Visvikis-Siest, Sophie S; Weill, Jacques J; Poulain-Godefroy, Odile O; Jacobson, Peter P; Sjostrom, Lars L; Hammond, Christopher J CJ; Deloukas, Panos P; Sham, Pak Chung PC; McPherson, Ruth R; Lee, Jeannette J; Tai, E Shyong ES; Sladek, Robert R; Carlsson, Lena M S LM; Walley, Andrew A; Eichler, Evan E EE; Pattou, Francois F; Spector, Timothy D TD; Froguel, Philippe P
Publication Date: 2014-05

Variant appearance in text: rs1421090
PubMed Link: 24686848
Variant Present in the following documents:
  • NIHMS57335-supplement-1.pdf
View BVdb publication page



Genetic variants in the Fat and Obesity Associated (FTO) gene and risk of Alzheimer's disease.

Plos One
Reitz, Christiane C; Tosto, Giuseppe G; Mayeux, Richard R; Luchsinger, Jose A JA; , ; ,
Publication Date: 2012

Variant appearance in text: rs1421090
PubMed Link: 23251365
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic association of SNPs in the FTO gene and predisposition to obesity in Malaysian Malays.

Brazilian Journal Of Medical And Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas
Apalasamy, Y D YD; Ming, M F MF; Rampal, S S; Bulgiba, A A; Mohamed, Z Z
Publication Date: 2012-12

Variant appearance in text: rs1421090
PubMed Link: 22911346
Variant Present in the following documents:
  • Main text
  • 0100-879X-bjmbr-45-12-1119.pdf
View BVdb publication page



Association of FTO gene variants with body composition in UK twins.

Annals Of Human Genetics
Livshits, Gregory G; Malkin, Ida I; Moayyeri, Alireza A; Spector, Timothy D TD; Hammond, Christopher J CJ
Publication Date: 2012-09

Variant appearance in text: rs1421090
PubMed Link: 22817777
Variant Present in the following documents:
  • Main text
  • ahg0076-0333.pdf
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Common variants in FTO are not significantly associated with obesity-related phenotypes among Samoans of Polynesia.

Annals Of Human Genetics
Karns, Rebekah R; Viali, Satupaitea S; Tuitele, John J; Sun, Guangyun G; Cheng, Hong H; Weeks, Daniel E DE; McGarvey, Stephen T ST; Deka, Ranjan R
Publication Date: 2012-01

Variant appearance in text: rs1421090
PubMed Link: 22084931
Variant Present in the following documents:
  • Main text
View BVdb publication page



Common SNPs in FTO gene are associated with obesity related anthropometric traits in an island population from the eastern Adriatic coast of Croatia.

Plos One
Zhang, Ge G; Karns, Rebekah R; Narancic, Nina Smolej NS; Sun, Guangyun G; Cheng, Hong H; Missoni, Sasa S; Durakovic, Zijad Z; Rudan, Pavao P; Chakraborty, Ranajit R; Deka, Ranjan R
Publication Date: 2010-04-28

Variant appearance in text: rs1421090
PubMed Link: 20442772
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany.

European Journal Of Human Genetics : Ejhg
Tönjes, Anke A; Zeggini, Eleftheria E; Kovacs, Peter P; Böttcher, Yvonne Y; Schleinitz, Dorit D; Dietrich, Kerstin K; Morris, Andrew P AP; Enigk, Beate B; Rayner, Nigel W NW; Koriath, Moritz M; Eszlinger, Markus M; Kemppinen, Anu A; Prokopenko, Inga I; Hoffmann, Katrin K; Teupser, Daniel D; Thiery, Joachim J; Krohn, Knut K; McCarthy, Mark I MI; Stumvoll, Michael M
Publication Date: 2010-01

Variant appearance in text: rs1421090
PubMed Link: 19584900
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP.

Plos One
Grant, Struan F A SF; Li, Mingyao M; Bradfield, Jonathan P JP; Kim, Cecilia E CE; Annaiah, Kiran K; Santa, Erin E; Glessner, Joseph T JT; Casalunovo, Tracy T; Frackelton, Edward C EC; Otieno, F George FG; Shaner, Julie L JL; Smith, Ryan M RM; Imielinski, Marcin M; Eckert, Andrew W AW; Chiavacci, Rosetta M RM; Berkowitz, Robert I RI; Hakonarson, Hakon H
Publication Date: 2008-03-12

Variant appearance in text: rs1421090
PubMed Link: 18335027
Variant Present in the following documents:
  • Main text
  • pone.0001746.pdf
View BVdb publication page