Publications:

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FTO m6A Demethylase in Obesity and Cancer: Implications and Underlying Molecular Mechanisms.

International Journal Of Molecular Sciences

Azzam, Sarah Kassem SK; Alsafar, Habiba H; Sajini, Abdulrahim A AA

Publication Date: 2022-03-30

Variant appearance in text: FTO: R96Q

PubMed Link: 35409166

Variant Present in the following documents:

• Main text
• ijms-23-03800.pdf

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DHA alleviates diet-induced skeletal muscle fiber remodeling via FTO/m6A/DDIT4/PGC1α signaling.

Bmc Biology

Chen, Wei W; Chen, Yushi Y; Wu, Ruifan R; Guo, Guanqun G; Liu, Youhua Y; Zeng, Botao B; Liao, Xing X; Wang, Yizhen Y; Wang, Xinxia X

Publication Date: 2022-02-08

Variant appearance in text: FTO: R96Q

PubMed Link: 35135551

Variant Present in the following documents:

• Main text
• 12915_2022_Article_1239.pdf

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DHA alleviates diet-induced skeletal muscle fiber remodeling via FTO/m6A/DDIT4/PGC1α signaling.

Bmc Biology

Chen, Wei W; Chen, Yushi Y; Wu, Ruifan R; Guo, Guanqun G; Liu, Youhua Y; Zeng, Botao B; Liao, Xing X; Wang, Yizhen Y; Wang, Xinxia X

Publication Date: 2022-02-08

Variant appearance in text: FTO: R96Q

PubMed Link: 35135551

Variant Present in the following documents:

• Main text
• 12915_2022_Article_1239.pdf

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m6A demethylation of cytidine deaminase APOBEC3B mRNA orchestrates arsenic-induced mutagenesis.

The Journal Of Biological Chemistry

Gao, Ming M; Qi, Zijuan Z; Feng, Wenya W; Huang, Hongyang H; Xu, Zhijie Z; Dong, Zheng Z; Xu, Ming M; Han, Jinxiang J; Kloeber, Jake A JA; Huang, Jinzhou J; Lou, Zhenkun Z; Liu, Sijin S

Publication Date: 2022-01-05

Variant appearance in text: FTO: R96Q

PubMed Link: 34998823

Variant Present in the following documents:

• Main text
• main.pdf
• mmc2.pdf

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m6A demethylation of cytidine deaminase APOBEC3B mRNA orchestrates arsenic-induced mutagenesis.

The Journal Of Biological Chemistry

Gao, Ming M; Qi, Zijuan Z; Feng, Wenya W; Huang, Hongyang H; Xu, Zhijie Z; Dong, Zheng Z; Xu, Ming M; Han, Jinxiang J; Kloeber, Jake A JA; Huang, Jinzhou J; Lou, Zhenkun Z; Liu, Sijin S

Publication Date: 2022-02

Variant appearance in text: FTO: R96Q

PubMed Link: 34998823

Variant Present in the following documents:

• Main text
• main.pdf
• mmc2.pdf

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RNA N6-methyladenosine demethylase FTO promotes osteoporosis through demethylating Runx2 mRNA and inhibiting osteogenic differentiation.

Aging

Wang, Jing J; Fu, Qiang Q; Yang, Jian J; Liu, Jin-Long JL; Hou, Shu-Ming SM; Huang, Xing X; Cao, Jia-Shi JS; Liu, Tie-Long TL; Wang, Kun-Zheng KZ

Publication Date: 2021-09-08

Variant appearance in text: FTO: R96Q

PubMed Link: 34496349

Variant Present in the following documents:

• Main text
• aging-13-203377.pdf

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Epigenetic regulation of N6-methyladenosine modifications in obesity.

Journal Of Diabetes Investigation

Sun, Mingli M; Zhang, Xinan X

Publication Date: 2021-08

Variant appearance in text: FTO: R96Q

PubMed Link: 33979018

Variant Present in the following documents:

• Main text

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N6-methyladenosine demethylase FTO impairs hepatic ischemia-reperfusion injury via inhibiting Drp1-mediated mitochondrial fragmentation.

Cell Death & Disease

Du, Ying Dong YD; Guo, Wen Yuan WY; Han, Cong Hui CH; Wang, Ying Y; Chen, Xiao Song XS; Li, Da Wei DW; Liu, Jin Long JL; Zhang, Ming M; Zhu, Nan N; Wang, Xin X

Publication Date: 2021-05-04

Variant appearance in text: FTO: R96Q

PubMed Link: 33947842

Variant Present in the following documents:

• Main text

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FTO Facilitates Lung Adenocarcinoma Cell Progression by Activating Cell Migration Through mRNA Demethylation.

Oncotargets And Therapy

Ding, Yudi Y; Qi, Nana N; Wang, Ke K; Huang, Yiming Y; Liao, Jinling J; Wang, Hongxue H; Tan, Aihua A; Liu, Lihua L; Zhang, Zhenqiang Z; Li, Jinlong J; Kong, Jinliang J; Qin, Shouming S; Jiang, Yonghua Y

Publication Date: 2020

Variant appearance in text: FTO: R96Q

PubMed Link: 32110044

Variant Present in the following documents:

• Main text
• ott-13-1461.pdf

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FTO is required for myogenesis by positively regulating mTOR-PGC-1α pathway-mediated mitochondria biogenesis.

Cell Death & Disease

Wang, Xiaobo X; Huang, Ning N; Yang, Min M; Wei, Dandan D; Tai, Haoran H; Han, Xiaojuan X; Gong, Hui H; Zhou, Jiao J; Qin, Jianqiong J; Wei, Xiawei X; Chen, Honghan H; Fang, Tingting T; Xiao, Hengyi H

Publication Date: 2017-03-23

Variant appearance in text: FTO: R96Q

PubMed Link: 28333151

Variant Present in the following documents:

• Main text
• cddis2017122a.pdf

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Role of FTO in Adipocyte Development and Function: Recent Insights.

International Journal Of Endocrinology

Merkestein, Myrte M; Sellayah, Dyan D

Publication Date: 2015

Variant appearance in text: FTO: R96Q

PubMed Link: 26788058

Variant Present in the following documents:

• Main text
• IJE2015-521381.pdf

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Recurrent inactivating RASA2 mutations in melanoma.

Nature Genetics

Arafeh, Rand R; Qutob, Nouar N; Emmanuel, Rafi R; Keren-Paz, Alona A; Madore, Jason J; Elkahloun, Abdel A; Wilmott, James S JS; Gartner, Jared J JJ; Di Pizio, Antonella A; Winograd-Katz, Sabina S; Sindiri, Sivasish S; Rotkopf, Ron R; Dutton-Regester, Ken K; Johansson, Peter P; Pritchard, Antonia L AL; Waddell, Nicola N; Hill, Victoria K VK; Lin, Jimmy C JC; Hevroni, Yael Y; Rosenberg, Steven A SA; Khan, Javed J; Ben-Dor, Shifra S; Niv, Masha Y MY; Ulitsky, Igor I; Mann, Graham J GJ; Scolyer, Richard A RA; Hayward, Nicholas K NK; Samuels, Yardena Y

Publication Date: 2015-12

Variant appearance in text: FTO: R96Q

PubMed Link: 26502337

Variant Present in the following documents:

• NIHMS65345-supplement-Supplementary_table_3.xlsx, sheet 1

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The Demethylase Activity of FTO (Fat Mass and Obesity Associated Protein) Is Required for Preadipocyte Differentiation.

Plos One

Zhang, Meizi M; Zhang, Ying Y; Ma, Jun J; Guo, Feima F; Cao, Qian Q; Zhang, Yu Y; Zhou, Bin B; Chai, Jijie J; Zhao, Wenqing W; Zhao, Renbin R

Publication Date: 2015

Variant appearance in text: FTO: R96Q

PubMed Link: 26218273

Variant Present in the following documents:

• Main text
• pone.0133788.pdf

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