FTO c.361A>C ;(p.K121Q)

Variant ID: 16-53860013-A-C

NM_001080432.2(FTO):c.361A>C;(p.K121Q)

This variant was identified in 33 publications

View GRCh38 version.




Publications:


Current Studies on Molecular Mechanisms of Insulin Resistance.

Journal Of Diabetes Research
Pei, Jinli J; Wang, Baochun B; Wang, Dayong D
Publication Date: 2022

Variant appearance in text: FTO: Lys121Gln
PubMed Link: 36589630
Variant Present in the following documents:
  • JDR2022-1863429.pdf
View BVdb publication page



G Allele of the rs1801282 Polymorphism in PPARγ Gene Confers an Increased Risk of Obesity and Hypercholesterolemia, While T Allele of the rs3856806 Polymorphism Displays a Protective Role Against Dyslipidemia: A Systematic Review and Meta-Analysis.

Frontiers In Endocrinology
Li, Shujin S; He, Chuan C; Nie, Haiyan H; Pang, Qianyin Q; Wang, Ruixia R; Zeng, Zhifu Z; Song, Yongyan Y
Publication Date: 2022

Variant appearance in text: FTO: K121Q
PubMed Link: 35846293
Variant Present in the following documents:
  • fendo-13-919087.pdf
View BVdb publication page



Coronary Heart Disease in Type 2 Diabetes Mellitus: Genetic Factors and Their Mechanisms, Gene-Gene, and Gene-Environment Interactions in the Asian Populations.

International Journal Of Environmental Research And Public Health
Zarkasi, Khairul Anwar KA; Abdul Murad, Nor Azian NA; Ahmad, Norfazilah N; Jamal, Rahman R; Abdullah, Noraidatulakma N
Publication Date: 2022-01-06

Variant appearance in text: FTO: K121Q
PubMed Link: 35055468
Variant Present in the following documents:
  • Main text
  • ijerph-19-00647.pdf
View BVdb publication page



Coronary Heart Disease in Type 2 Diabetes Mellitus: Genetic Factors and Their Mechanisms, Gene-Gene, and Gene-Environment Interactions in the Asian Populations.

International Journal Of Environmental Research And Public Health
Zarkasi, Khairul Anwar KA; Abdul Murad, Nor Azian NA; Ahmad, Norfazilah N; Jamal, Rahman R; Abdullah, Noraidatulakma N
Publication Date: 2022-01-06

Variant appearance in text: FTO: K121Q
PubMed Link: 35055468
Variant Present in the following documents:
  • Main text
  • ijerph-19-00647.pdf
View BVdb publication page



The genetic susceptibility profile of type 2 diabetes and reflection of its possible role related to reproductive dysfunctions in the southern Indian population of Hyderabad.

Bmc Medical Genomics
Irgam, Kumuda K; Reddy, Battini Sriteja BS; Hari, Sai Gayathri SG; Banapuram, Swathi S; Reddy, Battini Mohan BM
Publication Date: 2021-11-16

Variant appearance in text: FTO: K121Q
PubMed Link: 34784930
Variant Present in the following documents:
  • 12920_2021_Article_1129.pdf
View BVdb publication page



Nutrigenomics in Regulating the Expression of Genes Related to Type 2 Diabetes Mellitus.

Frontiers In Physiology
Felisbino, Karoline K; Granzotti, Juliano Gomes JG; Bello-Santos, Larissa L; Guiloski, Izonete Cristina IC
Publication Date: 2021

Variant appearance in text: FTO: K121Q
PubMed Link: 34366888
Variant Present in the following documents:
  • fphys-12-699220.pdf
View BVdb publication page



Genetic polymorphisms associated with obesity in the Arab world: a systematic review.

International Journal Of Obesity (2005)
Younes, Salma S; Ibrahim, Amal A; Al-Jurf, Rana R; Zayed, Hatem H
Publication Date: 2021-09

Variant appearance in text: FTO: K121Q
PubMed Link: 34131278
Variant Present in the following documents:
  • Main text
  • 41366_2021_867_MOESM3_ESM.xlsx, sheet 1
  • 41366_2021_Article_867.pdf
View BVdb publication page



Ten SNPs May Affect Type 2 Diabetes Risk in Interaction with Prenatal Exposure to Chinese Famine.

Nutrients
Song, Chao C; Ding, Caicui C; Yuan, Fan F; Feng, Ganyu G; Ma, Yanning Y; Liu, Ailing A
Publication Date: 2020-12-18

Variant appearance in text: FTO: K121Q
PubMed Link: 33353041
Variant Present in the following documents:
  • Main text
  • nutrients-12-03880.pdf
View BVdb publication page



PPARG (Pro12Ala) genetic variant and risk of T2DM: a systematic review and meta-analysis.

Scientific Reports
Sarhangi, Negar N; Sharifi, Farshad F; Hashemian, Leila L; Hassani Doabsari, Maryam M; Heshmatzad, Katayoun K; Rahbaran, Marzieh M; Jamaldini, Seyed Hamid SH; Aghaei Meybodi, Hamid Reza HR; Hasanzad, Mandana M
Publication Date: 2020-07-29

Variant appearance in text: FTO: K121Q
PubMed Link: 32728045
Variant Present in the following documents:
  • 41598_2020_Article_69363.pdf
  • 41598_2020_69363_MOESM12_ESM.pdf
View BVdb publication page



MC4R and ENPP1 gene polymorphisms and their implication in maternal and neonatal risk for obesity.

Scientific Reports
Mărginean, Claudiu C; Mărginean, Cristina Oana CO; Iancu, Mihaela M; Meliț, Lorena Elena LE; Tripon, Florin F; Bănescu, Claudia C
Publication Date: 2019-07-26

Variant appearance in text: FTO: K121Q
PubMed Link: 31350533
Variant Present in the following documents:
  • Main text
  • 41598_2019_Article_47402.pdf
View BVdb publication page



New Insights Regarding Genetic Aspects of Childhood Obesity: A Minireview.

Frontiers In Pediatrics
Mǎrginean, Cristina Oana CO; Mǎrginean, Claudiu C; Meliţ, Lorena Elena LE
Publication Date: 2018

Variant appearance in text: FTO: K121Q
PubMed Link: 30338250
Variant Present in the following documents:
  • Main text
View BVdb publication page



Body mass index modulates the association between CDKAL1 rs10946398 variant and type 2 diabetes among Taiwanese women.

Scientific Reports
Nfor, Oswald Ndi ON; Wu, Ming-Fang MF; Lee, Chun-Te CT; Wang, Lee L; Liu, Wen-Hsiu WH; Tantoh, Disline Manli DM; Hsu, Shu-Yi SY; Lee, Kuan-Jung KJ; Ho, Chien-Chang CC; Debnath, Tonmoy T; Lung, Chia-Chi CC; Liaw, Yung-Po YP
Publication Date: 2018-09-05

Variant appearance in text: FTO: K121Q
PubMed Link: 30185902
Variant Present in the following documents:
  • 41598_2018_Article_31415.pdf
View BVdb publication page



Transforming growth factor-β signaling pathway-associated genes SMAD2 and TGFBR2 are implicated in metabolic syndrome in a Taiwanese population.

Scientific Reports
Lin, Eugene E; Kuo, Po-Hsiu PH; Liu, Yu-Li YL; Yang, Albert C AC; Tsai, Shih-Jen SJ
Publication Date: 2017-10-19

Variant appearance in text: FTO: K121Q
PubMed Link: 29051557
Variant Present in the following documents:
  • 41598_2017_Article_14025.pdf
View BVdb publication page



The ADAMTS9 gene is associated with cognitive aging in the elderly in a Taiwanese population.

Plos One
Lin, Eugene E; Tsai, Shih-Jen SJ; Kuo, Po-Hsiu PH; Liu, Yu-Li YL; Yang, Albert C AC; Kao, Chung-Feng CF; Yang, Cheng-Hung CH
Publication Date: 2017

Variant appearance in text: FTO: K121Q
PubMed Link: 28225792
Variant Present in the following documents:
  • pone.0172440.pdf
View BVdb publication page



Genetic factors that affect nonalcoholic fatty liver disease: A systematic clinical review.

World Journal Of Gastroenterology
Severson, Tyler J TJ; Besur, Siddesh S; Bonkovsky, Herbert L HL
Publication Date: 2016-08-07

Variant appearance in text: FTO: Lys121Gln
PubMed Link: 27547017
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of the -243A>G, +61450C>A Polymorphisms of the Glutamate Decarboxylase 2 (GAD2) Gene with Obesity and Insulin Level in North Indian Population.

Iranian Journal Of Public Health
Prakash, Jai J; Mittal, Balraj B; Awasthi, Shally S; Srivastava, Neena N
Publication Date: 2016-04

Variant appearance in text: FTO: K121Q
PubMed Link: 27252915
Variant Present in the following documents:
  • IJPH-45-460.pdf
View BVdb publication page



Contribution of ENPP1, TCF7L2, and FTO polymorphisms to type 2 diabetes in mixed ancestry ethnic population of South Africa.

African Health Sciences
Yako, Yandiswa Y YY; Madubedube, Jabulisile H JH; Kengne, Andre P AP; Erasmus, Rajiv T RT; Pillay, Tahir S TS; Matsha, Tandi E TE
Publication Date: 2015-12

Variant appearance in text: FTO: K121Q
PubMed Link: 26958016
Variant Present in the following documents:
  • Main text
View BVdb publication page



Association of adiponectin gene polymorphism with adiponectin levels and risk for insulin resistance syndrome.

International Journal Of Preventive Medicine
Prakash, Jai J; Mittal, Balraj B; Awasthi, Shally S; Srivastava, Neena N
Publication Date: 2015

Variant appearance in text: FTO: K121Q
PubMed Link: 25949781
Variant Present in the following documents:
  • IJPVM-6-31.pdf
View BVdb publication page



Combined effect of established BMI loci on obesity-related traits in an Algerian population sample.

Bmc Genetics
Badsi, Manel Nassima MN; Mediene-Benchekor, Sounnia S; Ouhaibi-Djellouli, Hadjira H; Lardjam-Hetraf, Sarah Aicha SA; Boulenouar, Houssam H; Meroufel, Djabaria Naïma DN; Hermant, Xavier X; Hamani-Medjaoui, Imane I; Saidi-Mehtar, Nadhira N; Amouyel, Philippe P; Houti, Leila L; Meirhaeghe, Aline A; Goumidi, Louisa L
Publication Date: 2014-11-25

Variant appearance in text: FTO: K121Q
PubMed Link: 25422053
Variant Present in the following documents:
  • 12863_2014_Article_128.pdf
View BVdb publication page



Current Insights into the Joint Genetic Basis of Type 2 Diabetes and Coronary Heart Disease.

Current Cardiovascular Risk Reports
Dauriz, Marco M; Meigs, James B JB
Publication Date: 2014-01-01

Variant appearance in text: FTO: K121Q
PubMed Link: 24729826
Variant Present in the following documents:
  • Main text
View BVdb publication page



Maternal-fetal metabolic gene-gene interactions and risk of neural tube defects.

Molecular Genetics And Metabolism
Lupo, Philip J PJ; Mitchell, Laura E LE; Canfield, Mark A MA; Shaw, Gary M GM; Olshan, Andrew F AF; Finnell, Richard H RH; Zhu, Huiping H; ,
Publication Date: 2014-01

Variant appearance in text: FTO: K121Q
PubMed Link: 24332798
Variant Present in the following documents:
  • Main text
View BVdb publication page



The complex interplay of genetic and lifestyle risk factors in type 2 diabetes: an overview.

Scientifica
Franks, Paul W PW
Publication Date: 2012

Variant appearance in text: FTO: K121Q
PubMed Link: 24278702
Variant Present in the following documents:
  • SCIENTIFICA2012-482186.pdf
View BVdb publication page



Gene-environment and gene-treatment interactions in type 2 diabetes: progress, pitfalls, and prospects.

Diabetes Care
Franks, Paul W PW; Pearson, Ewan E; Florez, Jose C JC
Publication Date: 2013-05

Variant appearance in text: FTO: K121Q
PubMed Link: 23613601
Variant Present in the following documents:
  • Main text
  • 1413.pdf
View BVdb publication page



Genetic prediction of common diseases. Still no help for the clinical diabetologist!

Nutrition, Metabolism, And Cardiovascular Diseases : Nmcd
Prudente, S S; Dallapiccola, B B; Pellegrini, F F; Doria, A A; Trischitta, V V
Publication Date: 2012-11

Variant appearance in text: FTO: K121Q
PubMed Link: 22819342
Variant Present in the following documents:
  • Main text
View BVdb publication page



Post-renal transplant diabetes mellitus in korean subjects: superimposition of transplant-related immunosuppressant factors on genetic and type 2 diabetic risk factors.

Diabetes & Metabolism Journal
Lee, Hyun Chul HC
Publication Date: 2012-06

Variant appearance in text: FTO: K121Q
PubMed Link: 22737659
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular basis of obesity: current status and future prospects.

Current Genomics
Choquet, Hélène H; Meyre, David D
Publication Date: 2011-05

Variant appearance in text: FTO: K121Q
PubMed Link: 22043164
Variant Present in the following documents:
  • Main text
  • CG-12-154.pdf
View BVdb publication page



Association study of genetic variants in eight genes/loci with type 2 diabetes in a Han Chinese population.

Bmc Medical Genetics
Lin, Ying Y; Li, Pengqiu P; Cai, Li L; Zhang, Ben B; Tang, Xin X; Zhang, Xuejun X; Li, Ying Y; Xian, Yang Y; Yang, Yang Y; Wang, Li L; Lu, Fang F; Liu, Xiaoqi X; Rao, Shaoqin S; Chen, Ming M; Ma, Shi S; Shi, Yi Y; Bao, Mingjing M; Wu, Jichuan J; Yang, Yan Y; Yang, Jiyun J; Yang, Zhenglin Z
Publication Date: 2010-06-15

Variant appearance in text: FTO: K121Q
PubMed Link: 20550665
Variant Present in the following documents:
  • 1471-2350-11-97.pdf
View BVdb publication page



Genetic susceptibility to type 2 diabetes and implications for therapy.

Journal Of Diabetes Science And Technology
Florez, Jose C JC
Publication Date: 2009-07-01

Variant appearance in text: FTO: K121Q
PubMed Link: 20144315
Variant Present in the following documents:
  • Main text
View BVdb publication page



Metabolic syndrome components in murine models.

Endocrine, Metabolic & Immune Disorders Drug Targets
Lawson, Heather A HA; Cheverud, James M JM
Publication Date: 2010-03

Variant appearance in text: FTO: K121Q
PubMed Link: 20088816
Variant Present in the following documents:
  • Main text
View BVdb publication page



Recent progress in the genetics of common obesity.

British Journal Of Clinical Pharmacology
Loos, Ruth J F RJ
Publication Date: 2009-12

Variant appearance in text: FTO: Lys121Gln
PubMed Link: 20002076
Variant Present in the following documents:
  • Main text
View BVdb publication page



Contribution of type 2 diabetes associated loci in the Arabic population from Tunisia: a case-control study.

Bmc Medical Genetics
Ezzidi, Intissar I; Mtiraoui, Nabil N; Cauchi, Stéphane S; Vaillant, Emmanuel E; Dechaume, Aurélie A; Chaieb, Molka M; Kacem, Maha M; Almawi, Wassim Y WY; Froguel, Philippe P; Mahjoub, Touhami T; Vaxillaire, Martine M
Publication Date: 2009-04-15

Variant appearance in text: FTO: K121Q
PubMed Link: 19368707
Variant Present in the following documents:
  • 1471-2350-10-33.pdf
View BVdb publication page



Clinical review: the genetics of type 2 diabetes: a realistic appraisal in 2008.

The Journal Of Clinical Endocrinology And Metabolism
Florez, Jose C JC
Publication Date: 2008-12

Variant appearance in text: FTO: K121Q
PubMed Link: 18782870
Variant Present in the following documents:
  • Main text
View BVdb publication page



The emerging genetic architecture of type 2 diabetes.

Cell Metabolism
Doria, Alessandro A; Patti, Mary-Elizabeth ME; Kahn, C Ronald CR
Publication Date: 2008-09

Variant appearance in text: FTO: K121Q
PubMed Link: 18762020
Variant Present in the following documents:
  • Main text
View BVdb publication page