The utility of a type 2 diabetes polygenic score in addition to clinical variables for prediction of type 2 diabetes incidence in birth, youth and adult cohorts in an Indigenous study population.
Diabetologia
Wedekind, Lauren E LE; Mahajan, Anubha A; Hsueh, Wen-Chi WC; Chen, Peng P; Olaiya, Muideen T MT; Kobes, Sayuko S; Sinha, Madhumita M; Baier, Leslie J LJ; Knowler, William C WC; McCarthy, Mark I MI; Hanson, Robert L RL
Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis.
Journal Of The National Cancer Institute
Murphy, Neil N; Song, Mingyang M; Papadimitriou, Nikos N; Carreras-Torres, Robert R; Langenberg, Claudia C; Martin, Richard M RM; Tsilidis, Konstantinos K KK; Barroso, Inês I; Chen, Ji J; Frayling, Timothy M TM; Bull, Caroline J CJ; Vincent, Emma E EE; Cotterchio, Michelle M; Gruber, Stephen B SB; Pai, Rish K RK; Newcomb, Polly A PA; Perez-Cornago, Aurora A; van Duijnhoven, Franzel J B FJB; Van Guelpen, Bethany B; Vodicka, Pavel P; Wolk, Alicja A; Wu, Anna H AH; Peters, Ulrike U; Chan, Andrew T AT; Gunter, Marc J MJ
A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids.
Nature Communications
Jhun, Min-A MA; Mendelson, Michael M; Wilson, Rory R; Gondalia, Rahul R; Joehanes, Roby R; Salfati, Elias E; Zhao, Xiaoping X; Braun, Kim Valeska Emilie KVE; Do, Anh Nguyet AN; Hedman, Åsa K ÅK; Zhang, Tao T; Carnero-Montoro, Elena E; Shen, Jincheng J; Bartz, Traci M TM; Brody, Jennifer A JA; Montasser, May E ME; O'Connell, Jeff R JR; Yao, Chen C; Xia, Rui R; Boerwinkle, Eric E; Grove, Megan M; Guan, Weihua W; Liliane, Pfeiffer P; Singmann, Paula P; Müller-Nurasyid, Martina M; Meitinger, Thomas T; Gieger, Christian C; Peters, Annette A; Zhao, Wei W; Ware, Erin B EB; Smith, Jennifer A JA; Dhana, Klodian K; van Meurs, Joyce J; Uitterlinden, Andre A; Ikram, Mohammad Arfan MA; Ghanbari, Mohsen M; Zhi, Deugi D; Gustafsson, Stefan S; Lind, Lars L; Li, Shengxu S; Sun, Dianjianyi D; Spector, Tim D TD; Chen, Yii-der Ida YI; Damcott, Coleen C; Shuldiner, Alan R AR; Absher, Devin M DM; Horvath, Steve S; Tsao, Philip S PS; Kardia, Sharon S; Psaty, Bruce M BM; Sotoodehnia, Nona N; Bell, Jordana T JT; Ingelsson, Erik E; Chen, Wei W; Dehghan, Abbas A; Arnett, Donna K DK; Waldenberger, Melanie M; Hou, Lifang L; Whitsel, Eric A EA; Baccarelli, Andrea A; Levy, Daniel D; Fornage, Myriam M; Irvin, Marguerite R MR; Assimes, Themistocles L TL
Pharmacogenetic association of diabetes-associated genetic risk score with rapid progression of coronary artery calcification following treatment with HMG-CoA-reductase inhibitors -results of the Heinz Nixdorf Recall Study.
Naunyn-Schmiedeberg'S Archives Of Pharmacology
Pechlivanis, Sonali S; Jung, Dominik D; Moebus, Susanne S; Lehmann, Nils N; Mahabadi, Amir A AA; Hoffmann, Per P; Erbel, Raimund R; Nöthen, Markus M MM; Bachmann, Hagen S HS
Circulating Adiponectin and Its Association with Metabolic Traits and Type 2 Diabetes: Gene-Diet Interactions Focusing on Selected Gene Variants and at the Genome-Wide Level in High-Cardiovascular Risk Mediterranean Subjects.
Nutrients
Coltell, Oscar O; Ortega-Azorín, Carolina C; Sorlí, Jose V JV; Portolés, Olga O; Asensio, Eva M EM; Saiz, Carmen C; Barragán, Rocío R; Estruch, Ramon R; Corella, Dolores D
Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease.
Nature Communications
Nielsen, Jonas B JB; Rom, Oren O; Surakka, Ida I; Graham, Sarah E SE; Zhou, Wei W; Roychowdhury, Tanmoy T; Fritsche, Lars G LG; Gagliano Taliun, Sarah A SA; Sidore, Carlo C; Liu, Yuhao Y; Gabrielsen, Maiken E ME; Skogholt, Anne Heidi AH; Wolford, Brooke B; Overton, William W; Zhao, Ying Y; Chen, Jin J; Zhang, He H; Hornsby, Whitney E WE; Acheampong, Akua A; Grooms, Austen A; Schaefer, Amanda A; Zajac, Gregory J M GJM; Villacorta, Luis L; Zhang, Jifeng J; Brumpton, Ben B; Løset, Mari M; Rai, Vivek V; Lundegaard, Pia R PR; Olesen, Morten S MS; Taylor, Kent D KD; Palmer, Nicholette D ND; Chen, Yii-Der YD; Choi, Seung H SH; Lubitz, Steven A SA; Ellinor, Patrick T PT; Barnes, Kathleen C KC; Daya, Michelle M; Rafaels, Nicholas N; Weiss, Scott T ST; Lasky-Su, Jessica J; Tracy, Russell P RP; Vasan, Ramachandran S RS; Cupples, L Adrienne LA; Mathias, Rasika A RA; Yanek, Lisa R LR; Becker, Lewis C LC; Peyser, Patricia A PA; Bielak, Lawrence F LF; Smith, Jennifer A JA; Aslibekyan, Stella S; Hidalgo, Bertha A BA; Arnett, Donna K DK; Irvin, Marguerite R MR; Wilson, James G JG; Musani, Solomon K SK; Correa, Adolfo A; Rich, Stephen S SS; Guo, Xiuqing X; Rotter, Jerome I JI; Konkle, Barbara A BA; Johnsen, Jill M JM; Ashley-Koch, Allison E AE; Telen, Marilyn J MJ; Sheehan, Vivien A VA; Blangero, John J; Curran, Joanne E JE; Peralta, Juan M JM; Montgomery, Courtney C; Sheu, Wayne H-H WH; Chung, Ren-Hua RH; Schwander, Karen K; Nouraie, Seyed M SM; Gordeuk, Victor R VR; Zhang, Yingze Y; Kooperberg, Charles C; Reiner, Alexander P AP; Jackson, Rebecca D RD; Bleecker, Eugene R ER; Meyers, Deborah A DA; Li, Xingnan X; Das, Sayantan S; Yu, Ketian K; LeFaive, Jonathon J; Smith, Albert A; Blackwell, Tom T; Taliun, Daniel D; Zollner, Sebastian S; Forer, Lukas L; Schoenherr, Sebastian S; Fuchsberger, Christian C; Pandit, Anita A; Zawistowski, Matthew M; Kheterpal, Sachin S; Brummett, Chad M CM; Natarajan, Pradeep P; Schlessinger, David D; Lee, Seunggeun S; Kang, Hyun Min HM; Cucca, Francesco F; Holmen, Oddgeir L OL; Åsvold, Bjørn O BO; Boehnke, Michael M; Kathiresan, Sekar S; Abecasis, Goncalo R GR; Chen, Y Eugene YE; Willer, Cristen J CJ; Hveem, Kristian K
Circulating adipokine concentrations and risk of five obesity-related cancers: A Mendelian randomization study.
International Journal Of Cancer
Dimou, Niki L NL; Papadimitriou, Nikos N; Mariosa, Daniela D; Johansson, Mattias M; Brennan, Paul P; Peters, Ulrike U; Chanock, Stephen J SJ; Purdue, Mark M; Bishop, D Timothy DT; Gago-Dominquez, Manuela M; Giles, Graham G GG; Moreno, Victor V; Platz, Elizabeth A EA; Tangen, Catherine M CM; Wolk, Alicja A; Zheng, Wei W; Wu, Xifeng X; Campbell, Peter T PT; Giovannucci, Edward E; Lin, Yi Y; , ; Gunter, Marc J MJ; Murphy, Neil N
Identification of type 2 diabetes loci in 433,540 East Asian individuals.
Nature
Spracklen, Cassandra N CN; Horikoshi, Momoko M; Kim, Young Jin YJ; Lin, Kuang K; Bragg, Fiona F; Moon, Sanghoon S; Suzuki, Ken K; Tam, Claudia H T CHT; Tabara, Yasuharu Y; Kwak, Soo-Heon SH; Takeuchi, Fumihiko F; Long, Jirong J; Lim, Victor J Y VJY; Chai, Jin-Fang JF; Chen, Chien-Hsiun CH; Nakatochi, Masahiro M; Yao, Jie J; Choi, Hyeok Sun HS; Iyengar, Apoorva K AK; Perrin, Hannah J HJ; Brotman, Sarah M SM; van de Bunt, Martijn M; Gloyn, Anna L AL; Below, Jennifer E JE; Boehnke, Michael M; Bowden, Donald W DW; Chambers, John C JC; Mahajan, Anubha A; McCarthy, Mark I MI; Ng, Maggie C Y MCY; Petty, Lauren E LE; Zhang, Weihua W; Morris, Andrew P AP; Adair, Linda S LS; Akiyama, Masato M; Bian, Zheng Z; Chan, Juliana C N JCN; Chang, Li-Ching LC; Chee, Miao-Li ML; Chen, Yii-Der Ida YI; Chen, Yuan-Tsong YT; Chen, Zhengming Z; Chuang, Lee-Ming LM; Du, Shufa S; Gordon-Larsen, Penny P; Gross, Myron M; Guo, Xiuqing X; Guo, Yu Y; Han, Sohee S; Howard, Annie-Green AG; Huang, Wei W; Hung, Yi-Jen YJ; Hwang, Mi Yeong MY; Hwu, Chii-Min CM; Ichihara, Sahoko S; Isono, Masato M; Jang, Hye-Mi HM; Jiang, Guozhi G; Jonas, Jost B JB; Kamatani, Yoichiro Y; Katsuya, Tomohiro T; Kawaguchi, Takahisa T; Khor, Chiea-Chuen CC; Kohara, Katsuhiko K; Lee, Myung-Shik MS; Lee, Nanette R NR; Li, Liming L; Liu, Jianjun J; Luk, Andrea O AO; Lv, Jun J; Okada, Yukinori Y; Pereira, Mark A MA; Sabanayagam, Charumathi C; Shi, Jinxiu J; Shin, Dong Mun DM; So, Wing Yee WY; Takahashi, Atsushi A; Tomlinson, Brian B; Tsai, Fuu-Jen FJ; van Dam, Rob M RM; Xiang, Yong-Bing YB; Yamamoto, Ken K; Yamauchi, Toshimasa T; Yoon, Kyungheon K; Yu, Canqing C; Yuan, Jian-Min JM; Zhang, Liang L; Zheng, Wei W; Igase, Michiya M; Cho, Yoon Shin YS; Rotter, Jerome I JI; Wang, Ya-Xing YX; Sheu, Wayne H H WHH; Yokota, Mitsuhiro M; Wu, Jer-Yuarn JY; Cheng, Ching-Yu CY; Wong, Tien-Yin TY; Shu, Xiao-Ou XO; Kato, Norihiro N; Park, Kyong-Soo KS; Tai, E-Shyong ES; Matsuda, Fumihiko F; Koh, Woon-Puay WP; Ma, Ronald C W RCW; Maeda, Shiro S; Millwood, Iona Y IY; Lee, Juyoung J; Kadowaki, Takashi T; Walters, Robin G RG; Kim, Bong-Jo BJ; Mohlke, Karen L KL; Sim, Xueling X
Classification of Type 2 Diabetes Genetic Variants and a Novel Genetic Risk Score Association With Insulin Clearance.
The Journal Of Clinical Endocrinology And Metabolism
Goodarzi, Mark O MO; Palmer, Nicholette D ND; Cui, Jinrui J; Guo, Xiuqing X; Chen, Yii-Der I YI; Taylor, Kent D KD; Raffel, Leslie J LJ; Wagenknecht, Lynne E LE; Buchanan, Thomas A TA; Hsueh, Willa A WA; Rotter, Jerome I JI
Colocalization of GWAS and eQTL signals at loci with multiple signals identifies additional candidate genes for body fat distribution.
Human Molecular Genetics
Wu, Ying Y; Broadaway, K Alaine KA; Raulerson, Chelsea K CK; Scott, Laura J LJ; Pan, Calvin C; Ko, Arthur A; He, Aiqing A; Tilford, Charles C; Fuchsberger, Christian C; Locke, Adam E AE; Stringham, Heather M HM; Jackson, Anne U AU; Narisu, Narisu N; Kuusisto, Johanna J; Pajukanta, Päivi P; Collins, Francis S FS; Boehnke, Michael M; Laakso, Markku M; Lusis, Aldons J AJ; Civelek, Mete M; Mohlke, Karen L KL
ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response.
Nature Communications
Adeyemo, Adebowale A AA; Zaghloul, Norann A NA; Chen, Guanjie G; Doumatey, Ayo P AP; Leitch, Carmen C CC; Hostelley, Timothy L TL; Nesmith, Jessica E JE; Zhou, Jie J; Bentley, Amy R AR; Shriner, Daniel D; Fasanmade, Olufemi O; Okafor, Godfrey G; Eghan, Benjamin B; Agyenim-Boateng, Kofi K; Chandrasekharappa, Settara S; Adeleye, Jokotade J; Balogun, William W; Owusu, Samuel S; Amoah, Albert A; Acheampong, Joseph J; Johnson, Thomas T; Oli, Johnnie J; Adebamowo, Clement C; , ; Collins, Francis F; Dunston, Georgia G; Rotimi, Charles N CN
Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology.
American Journal Of Human Genetics
Spracklen, Cassandra N CN; Karaderi, Tugce T; Yaghootkar, Hanieh H; Schurmann, Claudia C; Fine, Rebecca S RS; Kutalik, Zoltan Z; Preuss, Michael H MH; Lu, Yingchang Y; Wittemans, Laura B L LBL; Adair, Linda S LS; Allison, Matthew M; Amin, Najaf N; Auer, Paul L PL; Bartz, Traci M TM; Blüher, Matthias M; Boehnke, Michael M; Borja, Judith B JB; Bork-Jensen, Jette J; Broer, Linda L; Chasman, Daniel I DI; Chen, Yii-Der Ida YI; Chirstofidou, Paraskevi P; Demirkan, Ayse A; van Duijn, Cornelia M CM; Feitosa, Mary F MF; Garcia, Melissa E ME; Graff, Mariaelisa M; Grallert, Harald H; Grarup, Niels N; Guo, Xiuqing X; Haesser, Jeffrey J; Hansen, Torben T; Harris, Tamara B TB; Highland, Heather M HM; Hong, Jaeyoung J; Ikram, M Arfan MA; Ingelsson, Erik E; Jackson, Rebecca R; Jousilahti, Pekka P; Kähönen, Mika M; Kizer, Jorge R JR; Kovacs, Peter P; Kriebel, Jennifer J; Laakso, Markku M; Lange, Leslie A LA; Lehtimäki, Terho T; Li, Jin J; Li-Gao, Ruifang R; Lind, Lars L; Luan, Jian'an J; Lyytikäinen, Leo-Pekka LP; MacGregor, Stuart S; Mackey, David A DA; Mahajan, Anubha A; Mangino, Massimo M; Männistö, Satu S; McCarthy, Mark I MI; McKnight, Barbara B; Medina-Gomez, Carolina C; Meigs, James B JB; Molnos, Sophie S; Mook-Kanamori, Dennis D; Morris, Andrew P AP; de Mutsert, Renee R; Nalls, Mike A MA; Nedeljkovic, Ivana I; North, Kari E KE; Pennell, Craig E CE; Pradhan, Aruna D AD; Province, Michael A MA; Raitakari, Olli T OT; Raulerson, Chelsea K CK; Reiner, Alex P AP; Ridker, Paul M PM; Ripatti, Samuli S; Roberston, Neil N; Rotter, Jerome I JI; Salomaa, Veikko V; Sandoval-Zárate, America A AA; Sitlani, Colleen M CM; Spector, Tim D TD; Strauch, Konstantin K; Stumvoll, Michael M; Taylor, Kent D KD; Thuesen, Betina B; Tönjes, Anke A; Uitterlinden, Andre G AG; Venturini, Cristina C; Walker, Mark M; Wang, Carol A CA; Wang, Shuai S; Wareham, Nicholas J NJ; Willems, Sara M SM; Willems van Dijk, Ko K; Wilson, James G JG; Wu, Ying Y; Yao, Jie J; Young, Kristin L KL; Langenberg, Claudia C; Frayling, Timothy M TM; Kilpeläinen, Tuomas O TO; Lindgren, Cecilia M CM; Loos, Ruth J F RJF; Mohlke, Karen L KL
Genetic and secondary causes of severe HDL deficiency and cardiovascular disease.
Journal Of Lipid Research
Geller, Andrew S AS; Polisecki, Eliana Y EY; Diffenderfer, Margaret R MR; Asztalos, Bela F BF; Karathanasis, Sotirios K SK; Hegele, Robert A RA; Schaefer, Ernst J EJ
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.
Nature Genetics
Mahajan, Anubha A; Taliun, Daniel D; Thurner, Matthias M; Robertson, Neil R NR; Torres, Jason M JM; Rayner, N William NW; Payne, Anthony J AJ; Steinthorsdottir, Valgerdur V; Scott, Robert A RA; Grarup, Niels N; Cook, James P JP; Schmidt, Ellen M EM; Wuttke, Matthias M; Sarnowski, Chloé C; Mägi, Reedik R; Nano, Jana J; Gieger, Christian C; Trompet, Stella S; Lecoeur, Cécile C; Preuss, Michael H MH; Prins, Bram Peter BP; Guo, Xiuqing X; Bielak, Lawrence F LF; Below, Jennifer E JE; Bowden, Donald W DW; Chambers, John Campbell JC; Kim, Young Jin YJ; Ng, Maggie C Y MCY; Petty, Lauren E LE; Sim, Xueling X; Zhang, Weihua W; Bennett, Amanda J AJ; Bork-Jensen, Jette J; Brummett, Chad M CM; Canouil, Mickaël M; Ec Kardt, Kai-Uwe KU; Fischer, Krista K; Kardia, Sharon L R SLR; Kronenberg, Florian F; Läll, Kristi K; Liu, Ching-Ti CT; Locke, Adam E AE; Luan, Jian'an J; Ntalla, Ioanna I; Nylander, Vibe V; Schönherr, Sebastian S; Schurmann, Claudia C; Yengo, Loïc L; Bottinger, Erwin P EP; Brandslund, Ivan I; Christensen, Cramer C; Dedoussis, George G; Florez, Jose C JC; Ford, Ian I; Franco, Oscar H OH; Frayling, Timothy M TM; Giedraitis, Vilmantas V; Hackinger, Sophie S; Hattersley, Andrew T AT; Herder, Christian C; Ikram, M Arfan MA; Ingelsson, Martin M; Jørgensen, Marit E ME; Jørgensen, Torben T; Kriebel, Jennifer J; Kuusisto, Johanna J; Ligthart, Symen S; Lindgren, Cecilia M CM; Linneberg, Allan A; Lyssenko, Valeriya V; Mamakou, Vasiliki V; Meitinger, Thomas T; Mohlke, Karen L KL; Morris, Andrew D AD; Nadkarni, Girish G; Pankow, James S JS; Peters, Annette A; Sattar, Naveed N; Stančáková, Alena A; Strauch, Konstantin K; Taylor, Kent D KD; Thorand, Barbara B; Thorleifsson, Gudmar G; Thorsteinsdottir, Unnur U; Tuomilehto, Jaakko J; Witte, Daniel R DR; Dupuis, Josée J; Peyser, Patricia A PA; Zeggini, Eleftheria E; Loos, Ruth J F RJF; Froguel, Philippe P; Ingelsson, Erik E; Lind, Lars L; Groop, Leif L; Laakso, Markku M; Collins, Francis S FS; Jukema, J Wouter JW; Palmer, Colin N A CNA; Grallert, Harald H; Metspalu, Andres A; Dehghan, Abbas A; Köttgen, Anna A; Abecasis, Goncalo R GR; Meigs, James B JB; Rotter, Jerome I JI; Marchini, Jonathan J; Pedersen, Oluf O; Hansen, Torben T; Langenberg, Claudia C; Wareham, Nicholas J NJ; Stefansson, Kari K; Gloyn, Anna L AL; Morris, Andrew P AP; Boehnke, Michael M; McCarthy, Mark I MI
Genome-wide interaction with the insulin secretion locus MTNR1B reveals CMIP as a novel type 2 diabetes susceptibility gene in African Americans.
Genetic Epidemiology
Keaton, Jacob M JM; Gao, Chuan C; Guan, Meijian M; Hellwege, Jacklyn N JN; Palmer, Nicholette D ND; Pankow, James S JS; Fornage, Myriam M; Wilson, James G JG; Correa, Adolfo A; Rasmussen-Torvik, Laura J LJ; Rotter, Jerome I JI; Chen, Yii-Der I YI; Taylor, Kent D KD; Rich, Stephen S SS; Wagenknecht, Lynne E LE; Freedman, Barry I BI; Ng, Maggie C Y MCY; Bowden, Donald W DW
Polygenic determinants in extremes of high-density lipoprotein cholesterol.
Journal Of Lipid Research
Dron, Jacqueline S JS; Wang, Jian J; Low-Kam, Cécile C; Khetarpal, Sumeet A SA; Robinson, John F JF; McIntyre, Adam D AD; Ban, Matthew R MR; Cao, Henian H; Rhainds, David D; Dubé, Marie-Pierre MP; Rader, Daniel J DJ; Lettre, Guillaume G; Tardif, Jean-Claude JC; Hegele, Robert A RA
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
Diabetes
Scott, Robert A RA; Scott, Laura J LJ; Mägi, Reedik R; Marullo, Letizia L; Gaulton, Kyle J KJ; Kaakinen, Marika M; Pervjakova, Natalia N; Pers, Tune H TH; Johnson, Andrew D AD; Eicher, John D JD; Jackson, Anne U AU; Ferreira, Teresa T; Lee, Yeji Y; Ma, Clement C; Steinthorsdottir, Valgerdur V; Thorleifsson, Gudmar G; Qi, Lu L; Van Zuydam, Natalie R NR; Mahajan, Anubha A; Chen, Han H; Almgren, Peter P; Voight, Ben F BF; Grallert, Harald H; Müller-Nurasyid, Martina M; Ried, Janina S JS; Rayner, Nigel W NW; Robertson, Neil N; Karssen, Lennart C LC; van Leeuwen, Elisabeth M EM; Willems, Sara M SM; Fuchsberger, Christian C; Kwan, Phoenix P; Teslovich, Tanya M TM; Chanda, Pritam P; Li, Man M; Lu, Yingchang Y; Dina, Christian C; Thuillier, Dorothee D; Yengo, Loic L; Jiang, Longda L; Sparso, Thomas T; Kestler, Hans A HA; Chheda, Himanshu H; Eisele, Lewin L; Gustafsson, Stefan S; Frånberg, Mattias M; Strawbridge, Rona J RJ; Benediktsson, Rafn R; Hreidarsson, Astradur B AB; Kong, Augustine A; Sigurðsson, Gunnar G; Kerrison, Nicola D ND; Luan, Jian'an J; Liang, Liming L; Meitinger, Thomas T; Roden, Michael M; Thorand, Barbara B; Esko, Tõnu T; Mihailov, Evelin E; Fox, Caroline C; Liu, Ching-Ti CT; Rybin, Denis D; Isomaa, Bo B; Lyssenko, Valeriya V; Tuomi, Tiinamaija T; Couper, David J DJ; Pankow, James S JS; Grarup, Niels N; Have, Christian T CT; Jørgensen, Marit E ME; Jørgensen, Torben T; Linneberg, Allan A; Cornelis, Marilyn C MC; van Dam, Rob M RM; Hunter, David J DJ; Kraft, Peter P; Sun, Qi Q; Edkins, Sarah S; Owen, Katharine R KR; Perry, John R B JRB; Wood, Andrew R AR; Zeggini, Eleftheria E; Tajes-Fernandes, Juan J; Abecasis, Goncalo R GR; Bonnycastle, Lori L LL; Chines, Peter S PS; Stringham, Heather M HM; Koistinen, Heikki A HA; Kinnunen, Leena L; Sennblad, Bengt B; Mühleisen, Thomas W TW; Nöthen, Markus M MM; Pechlivanis, Sonali S; Baldassarre, Damiano D; Gertow, Karl K; Humphries, Steve E SE; Tremoli, Elena E; Klopp, Norman N; Meyer, Julia J; Steinbach, Gerald G; Wennauer, Roman R; Eriksson, Johan G JG; Mӓnnistö, Satu S; Peltonen, Leena L; Tikkanen, Emmi E; Charpentier, Guillaume G; Eury, Elodie E; Lobbens, Stéphane S; Gigante, Bruna B; Leander, Karin K; McLeod, Olga O; Bottinger, Erwin P EP; Gottesman, Omri O; Ruderfer, Douglas D; Blüher, Matthias M; Kovacs, Peter P; Tonjes, Anke A; Maruthur, Nisa M NM; Scapoli, Chiara C; Erbel, Raimund R; Jöckel, Karl-Heinz KH; Moebus, Susanne S; de Faire, Ulf U; Hamsten, Anders A; Stumvoll, Michael M; Deloukas, Panagiotis P; Donnelly, Peter J PJ; Frayling, Timothy M TM; Hattersley, Andrew T AT; Ripatti, Samuli S; Salomaa, Veikko V; Pedersen, Nancy L NL; Boehm, Bernhard O BO; Bergman, Richard N RN; Collins, Francis S FS; Mohlke, Karen L KL; Tuomilehto, Jaakko J; Hansen, Torben T; Pedersen, Oluf O; Barroso, Inês I; Lannfelt, Lars L; Ingelsson, Erik E; Lind, Lars L; Lindgren, Cecilia M CM; Cauchi, Stephane S; Froguel, Philippe P; Loos, Ruth J F RJF; Balkau, Beverley B; Boeing, Heiner H; Franks, Paul W PW; Barricarte Gurrea, Aurelio A; Palli, Domenico D; van der Schouw, Yvonne T YT; Altshuler, David D; Groop, Leif C LC; Langenberg, Claudia C; Wareham, Nicholas J NJ; Sijbrands, Eric E; van Duijn, Cornelia M CM; Florez, Jose C JC; Meigs, James B JB; Boerwinkle, Eric E; Gieger, Christian C; Strauch, Konstantin K; Metspalu, Andres A; Morris, Andrew D AD; Palmer, Colin N A CNA; Hu, Frank B FB; Thorsteinsdottir, Unnur U; Stefansson, Kari K; Dupuis, Josée J; Morris, Andrew P AP; Boehnke, Michael M; McCarthy, Mark I MI; Prokopenko, Inga I; ,
Genetic contribution to lipid levels in early life based on 158 loci validated in adults: the FAMILY study.
Scientific Reports
Christie, Shanice S; Robiou-du-Pont, Sébastien S; Anand, Sonia S SS; Morrison, Katherine M KM; McDonald, Sarah D SD; Paré, Guillaume G; Atkinson, Stephanie A SA; Teo, Koon K KK; Meyre, David D
Investigation of Genetic Variation Underlying Central Obesity amongst South Asians.
Plos One
Scott, William R WR; Zhang, Weihua W; Loh, Marie M; Tan, Sian-Tsung ST; Lehne, Benjamin B; Afzal, Uzma U; Peralta, Juan J; Saxena, Richa R; Ralhan, Sarju S; Wander, Gurpreet S GS; Bozaoglu, Kiymet K; Sanghera, Dharambir K DK; Elliott, Paul P; Scott, James J; Chambers, John C JC; Kooner, Jaspal S JS
Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese.
Nature Communications
Tang, Clara S CS; Zhang, He H; Cheung, Chloe Y Y CY; Xu, Ming M; Ho, Jenny C Y JC; Zhou, Wei W; Cherny, Stacey S SS; Zhang, Yan Y; Holmen, Oddgeir O; Au, Ka-Wing KW; Yu, Haiyi H; Xu, Lin L; Jia, Jia J; Porsch, Robert M RM; Sun, Lijie L; Xu, Weixian W; Zheng, Huiping H; Wong, Lai-Yung LY; Mu, Yiming Y; Dou, Jingtao J; Fong, Carol H Y CH; Wang, Shuyu S; Hong, Xueyu X; Dong, Liguang L; Liao, Yanhua Y; Wang, Jiansong J; Lam, Levina S M LS; Su, Xi X; Yan, Hua H; Yang, Min-Lee ML; Chen, Jin J; Siu, Chung-Wah CW; Xie, Gaoqiang G; Woo, Yu-Cho YC; Wu, Yangfeng Y; Tan, Kathryn C B KC; Hveem, Kristian K; Cheung, Bernard M Y BM; Zöllner, Sebastian S; Xu, Aimin A; Eugene Chen, Y Y; Jiang, Chao Qiang CQ; Zhang, Youyi Y; Lam, Tai-Hing TH; Ganesh, Santhi K SK; Huo, Yong Y; Sham, Pak C PC; Lam, Karen S L KS; Willer, Cristen J CJ; Tse, Hung-Fat HF; Gao, Wei W
Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease.
Journal Of The American Heart Association
Persson, Jonas J; Strawbridge, Rona J RJ; McLeod, Olga O; Gertow, Karl K; Silveira, Angela A; Baldassarre, Damiano D; Van Zuydam, Natalie N; Shah, Sonia S; Fava, Cristiano C; Gustafsson, Stefan S; Veglia, Fabrizio F; Sennblad, Bengt B; Larsson, Malin M; Sabater-Lleal, Maria M; Leander, Karin K; Gigante, Bruna B; Tabak, Adam A; Kivimaki, Mika M; Kauhanen, Jussi J; Rauramaa, Rainer R; Smit, Andries J AJ; Mannarino, Elmo E; Giral, Philippe P; Humphries, Steve E SE; Tremoli, Elena E; de Faire, Ulf U; Lind, Lars L; Ingelsson, Erik E; Hedblad, Bo B; Melander, Olle O; Kumari, Meena M; Hingorani, Aroon A; Morris, Andrew D AD; Palmer, Colin N A CN; Lundman, Pia P; Öhrvik, John J; Söderberg, Stefan S; Hamsten, Anders A; ,
A common variant in the CLDN7/ELP5 locus predicts adiponectin change with lifestyle intervention and improved fitness in obese individuals with diabetes.
Physiological Genomics
Belalcazar, L Maria LM; Papandonatos, George D GD; McCaffery, Jeanne M JM; Peter, Inga I; Pajewski, Nicholas M NM; Erar, Bahar B; Allred, Nicholette D ND; Balasubramanyam, Ashok A; Bowden, Donald W DW; Brautbar, Ariel A; Pi-Sunyer, F Xavier FX; Ballantyne, Christie M CM; Huggins, Gordon S GS; ,
New genetic loci link adipose and insulin biology to body fat distribution.
Nature
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Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.
Nature Communications
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LipidSeq: a next-generation clinical resequencing panel for monogenic dyslipidemias.
Journal Of Lipid Research
Johansen, Christopher T CT; Dubé, Joseph B JB; Loyzer, Melissa N MN; MacDonald, Austin A; Carter, David E DE; McIntyre, Adam D AD; Cao, Henian H; Wang, Jian J; Robinson, John F JF; Hegele, Robert A RA
Hypothesis-based analysis of gene-gene interactions and risk of myocardial infarction.
Plos One
Lucas, Gavin G; Lluís-Ganella, Carla C; Subirana, Isaac I; Musameh, Muntaser D MD; Gonzalez, Juan Ramon JR; Nelson, Christopher P CP; Sentí, Mariano M; , ; , ; Schwartz, Stephen M SM; Siscovick, David D; O'Donnell, Christopher J CJ; Melander, Olle O; Salomaa, Veikko V; Purcell, Shaun S; Altshuler, David D; Samani, Nilesh J NJ; Kathiresan, Sekar S; Elosua, Roberto R
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
Plos Genetics
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Biological, clinical and population relevance of 95 loci for blood lipids.
Nature
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