ERBB2 c.250G>C ;(p.V84L)

Variant ID: 17-37864598-G-C

NM_004448.2(ERBB2):c.250G>C;(p.V84L)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.

Nature Communications
Havugimana, Pierre C PC; Goel, Raghuveera Kumar RK; Phanse, Sadhna S; Youssef, Ahmed A; Padhorny, Dzmitry D; Kotelnikov, Sergei S; Kozakov, Dima D; Emili, Andrew A
Publication Date: 2022-07-13

Variant appearance in text: ERBB2: 250G>C
PubMed Link: 35831314
Variant Present in the following documents:
  • 41467_2022_31809_MOESM8_ESM.xlsx, sheet 3
View BVdb publication page



A single mutation increases heavy-chain heterodimer assembly of bispecific antibodies by inducing structural disorder in one homodimer species.

The Journal Of Biological Chemistry
Stutz, Cian C; Blein, Stanislas S
Publication Date: 2020-07-10

Variant appearance in text: HER2: V84L
PubMed Link: 32404368
Variant Present in the following documents:
  • Main text
  • zbc9392.pdf
View BVdb publication page



Immunoglobulin domain interface exchange as a platform technology for the generation of Fc heterodimers and bispecific antibodies.

The Journal Of Biological Chemistry
Skegro, Darko D; Stutz, Cian C; Ollier, Romain R; Svensson, Emelie E; Wassmann, Paul P; Bourquin, Florence F; Monney, Thierry T; Gn, Sunitha S; Blein, Stanislas S
Publication Date: 2017-06-09

Variant appearance in text: HER2: V84L
PubMed Link: 28450393
Variant Present in the following documents:
  • Main text
  • zbc9745.pdf
View BVdb publication page