ERBB2 c.488A>G ;(p.Y163C)

Variant ID: 17-37865619-A-G

NM_004448.2(ERBB2):c.488A>G;(p.Y163C)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


Omics analyses of a somatic <i>Trp53<sup>R245W/+</sup></i> breast cancer model identify cooperating driver events activating PI3K/AKT/mTOR signaling.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Yu, Xiaojie X; Zhang, Yun Y; Xiong, Shunbin S; McDaniel, Joy M JM; Sun, Chang C; Chau, Gilda P GP; Gencel-Augusto, Jovanka J; Chachad, Dhruv D; Morrissey, Rhiannon L RL; Rao, Xiayu X; Wang, Jing J; Lozano, Guillermina G
Publication Date: 2022-11-08

Variant appearance in text: HER2: Y163C
PubMed Link: 36322759
Variant Present in the following documents:
  • pnas.2210618119.sapp.pdf
View BVdb publication page



The Genomics of Young Lung Cancer: Comprehensive Tissue Genomic Analysis in Patients Under 40 With Lung Cancer.

Jto Clinical And Research Reports
Gitlitz, Barbara J BJ; Novello, Silvia S; Vavalà, Tiziana T; Bittoni, Marisa M; Sable-Hunt, Alicia A; Pavlick, Dean D; Hsu, Robert R; Park, S Lani SL; Chen, Ruthia R; Cooke, Matthew M; Moore, Amy A; Schrock, Alexa B AB; Schiller, Joan H JH; Addario, Bonnie J BJ; Oxnard, Geoffrey R GR
Publication Date: 2021-07

Variant appearance in text: ERBB2: Y163C
PubMed Link: 34590039
Variant Present in the following documents:
  • Main text
View BVdb publication page



Circadian PERformance in breast cancer: a germline and somatic genetic study of PER3VNTR polymorphisms and gene co-expression.

Npj Breast Cancer
Fores-Martos, Jaume J; Cervera-Vidal, Raimundo R; Sierra-Roca, Julia J; Lozano-Asencio, Carlos C; Fedele, Vita V; Cornelissen, Sten S; Edvarsen, Hege H; Tadeo-Cervera, Irene I; Eroles, Pilar P; Lluch, Ana A; Tabares-Seisdedos, Rafa R; Falcó, Antonio A; Van't Veer, Laura J LJ; Schmidt, Marjanka M; Quigley, David A DA; Børresen-Dale, Anne-Lise AL; Kristensen, Vessela N VN; Balmain, Allan A; Climent, Joan J
Publication Date: 2021-09-10

Variant appearance in text: HER2: Y163C
PubMed Link: 34508103
Variant Present in the following documents:
  • 41523_2021_329_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast.

Communications Biology
Nagasawa, Satoi S; Kuze, Yuta Y; Maeda, Ichiro I; Kojima, Yasuyuki Y; Motoyoshi, Ai A; Onishi, Tatsuya T; Iwatani, Tsuguo T; Yokoe, Takamichi T; Koike, Junki J; Chosokabe, Motohiro M; Kubota, Manabu M; Seino, Hibiki H; Suzuki, Ayako A; Seki, Masahide M; Tsuchihara, Katsuya K; Inoue, Eisuke E; Tsugawa, Koichiro K; Ohta, Tomohiko T; Suzuki, Yutaka Y
Publication Date: 2021-04-01

Variant appearance in text: ERBB2: Y163C
PubMed Link: 33795819
Variant Present in the following documents:
  • 42003_2021_1959_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Incidence and distribution of UroSEEK gene panel in a multi-institutional cohort of bladder urothelial carcinoma.

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc
Eich, Marie-Lisa ML; Rodriguez Pena, Maria Del Carmen MDC; Springer, Simeon U SU; Taheri, Diana D; Tregnago, Aline C AC; Salles, Daniela C DC; Bezerra, Stephania Martins SM; Cunha, Isabela W IW; Fujita, Kazutoshi K; Ertoy, Dilek D; Bivalacqua, Trinity J TJ; Tomasetti, Cristian C; Papadopoulos, Nickolas N; Kinzler, Ken W KW; Vogelstein, Bert B; Netto, George J GJ
Publication Date: 2019-10

Variant appearance in text: ERBB2: Y163C
PubMed Link: 31028363
Variant Present in the following documents:
  • NIHMS1525315-supplement-2.xlsx, sheet 1
View BVdb publication page



Molecular characterization of breast cancer cell lines through multiple omic approaches.

Breast Cancer Research : Bcr
Smith, Shari E SE; Mellor, Paul P; Ward, Alison K AK; Kendall, Stephanie S; McDonald, Megan M; Vizeacoumar, Frederick S FS; Vizeacoumar, Franco J FJ; Napper, Scott S; Anderson, Deborah H DH
Publication Date: 2017-06-05

Variant appearance in text: HER2: Y163C
PubMed Link: 28583138
Variant Present in the following documents:
  • 13058_2017_855_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Mutation status among patients with sinonasal mucosal melanoma and its impact on survival.

British Journal Of Cancer
Amit, Moran M; Tam, Samantha S; Abdelmeguid, Ahmed S AS; Roberts, Dianna B DB; Takahashi, Yoko Y; Raza, Shaan M SM; Su, Shirley Y SY; Kupferman, Michael E ME; DeMonte, Franco F; Hanna, Ehab Y EY
Publication Date: 2017-06-06

Variant appearance in text: ERBB2: Y163C
PubMed Link: 28494469
Variant Present in the following documents:
  • bjc2017125a.pdf
View BVdb publication page



Evaluation of public cancer datasets and signatures identifies TP53 mutant signatures with robust prognostic and predictive value.

Bmc Cancer
Lehmann, Brian David BD; Ding, Yan Y; Viox, Daniel Joseph DJ; Jiang, Ming M; Zheng, Yi Y; Liao, Wang W; Chen, Xi X; Xiang, Wei W; Yi, Yajun Y
Publication Date: 2015-03-26

Variant appearance in text: HER2: Y163C
PubMed Link: 25886164
Variant Present in the following documents:
  • 12885_2015_1102_MOESM1_ESM.pdf
View BVdb publication page



BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations.

Bmc Cancer
Holstege, Henne H; Horlings, Hugo M HM; Velds, Arno A; Langerød, Anita A; Børresen-Dale, Anne-Lise AL; van de Vijver, Marc J MJ; Nederlof, Petra M PM; Jonkers, Jos J
Publication Date: 2010-11-30

Variant appearance in text: HER2: Y163C
PubMed Link: 21118481
Variant Present in the following documents:
  • Main text
View BVdb publication page