Publications:

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Calibration of computational tools for missense variant pathogenicity classification and ClinGen recommendations for PP3/BP4 criteria.

American Journal Of Human Genetics

Pejaver, Vikas V; Byrne, Alicia B AB; Feng, Bing-Jian BJ; Pagel, Kymberleigh A KA; Mooney, Sean D SD; Karchin, Rachel R; O'Donnell-Luria, Anne A; Harrison, Steven M SM; Tavtigian, Sean V SV; Greenblatt, Marc S MS; Biesecker, Leslie G LG; Radivojac, Predrag P; Brenner, Steven E SE; ,

Publication Date: 2022-12-01

Variant appearance in text: ERBB2: A293T; rs1258412021

PubMed Link: 36413997

Variant Present in the following documents:

• mmc3.xlsx, sheet 1

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Computational and Functional Analyses of HER2 Mutations Reveal Allosteric Activation Mechanisms and Altered Pharmacologic Effects.

Cancer Research

Ishiyama, Noboru N; O'Connor, Matthew M; Salomatov, Andrei A; Romashko, Darlene D; Thakur, Shalabh S; Mentes, Ahmet A; Hopkins, Julia F JF; Frampton, Garrett M GM; Albacker, Lee A LA; Kohlmann, Anna A; Roberts, Christopher C; Buck, Elizabeth E

Publication Date: 2022-05-03

Variant appearance in text: HER2: A293T

PubMed Link: 35503682

Variant Present in the following documents:

• Main text
• 1531.pdf

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Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.

Nature Biotechnology

Sánchez-Rivera, Francisco J FJ; Diaz, Bianca J BJ; Kastenhuber, Edward R ER; Schmidt, Henri H; Katti, Alyna A; Kennedy, Margaret M; Tem, Vincent V; Ho, Yu-Jui YJ; Leibold, Josef J; Paffenholz, Stella V SV; Barriga, Francisco M FM; Chu, Kevan K; Goswami, Sukanya S; Wuest, Alexandra N AN; Simon, Janelle M JM; Tsanov, Kaloyan M KM; Chakravarty, Debyani D; Zhang, Hongxin H; Leslie, Christina S CS; Lowe, Scott W SW; Dow, Lukas E LE

Publication Date: 2022-06

Variant appearance in text: ERBB2: A293T

PubMed Link: 35165384

Variant Present in the following documents:

• NIHMS1760571-supplement-Supplementary_Table_S2.xlsx, sheet 4
• NIHMS1760571-supplement-Supplementary_Table_S7.xlsx, sheet 5
• NIHMS1760571-supplement-Supplementary_Table_S2.xlsx, sheet 6

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Prognostic Impact of An Integrative Landscape of Clinical, Immune, and Molecular Features in Non-Metastatic Rectal Cancer.

Frontiers In Oncology

Iseas, Soledad S; Sendoya, Juan M JM; Robbio, Juan J; Coraglio, Mariana M; Kujaruk, Mirta M; Mikolaitis, Vanesa V; Rizzolo, Mariana M; Cabanne, Ana A; Ruiz, Gonzalo G; Salanova, Rubén R; Gualdrini, Ubaldo U; Méndez, Guillermo G; Antelo, Marina M; Carballido, Marcela M; Rotondaro, Cecilia C; Viglino, Julieta J; Eleta, Martín M; Di Sibio, Alejandro A; Podhajcer, Osvaldo L OL; Roca, Enrique E; Llera, Andrea S AS; Golubicki, Mariano M; Abba, Martín Carlos MC

Publication Date: 2021

Variant appearance in text: ERBB2: A293T

PubMed Link: 35071006

Variant Present in the following documents:

• Table_4.xlsx, sheet 1

View BVdb publication page

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Molecularly annotation of mouse avatar models derived from patients with colorectal cancer liver metastasis.

Theranostics

Wang, Jingyuan J; Xing, Baocai B; Liu, Wei W; Li, Jian J; Wang, Xicheng X; Li, Juan J; Yang, Jing J; Ji, Congcong C; Li, Zhongwu Z; Dong, Bin B; Gao, Jing J; Shen, Lin L

Publication Date: 2019

Variant appearance in text: ERBB2: A293T

PubMed Link: 31281492

Variant Present in the following documents:

• Main text
• thnov09p3485.pdf

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: ERBB2: A293T

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

View BVdb publication page

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Experience with precision genomics and tumor board, indicates frequent target identification, but barriers to delivery.

Oncotarget

Bryce, Alan H AH; Egan, Jan B JB; Borad, Mitesh J MJ; Stewart, A Keith AK; Nowakowski, Grzegorz S GS; Chanan-Khan, Asher A; Patnaik, Mrinal M MM; Ansell, Stephen M SM; Banck, Michaela S MS; Robinson, Steven I SI; Mansfield, Aaron S AS; Klee, Eric W EW; Oliver, Gavin R GR; McCormick, Jennifer B JB; Huneke, Norine E NE; Tagtow, Colleen M CM; Jenkins, Robert B RB; Rumilla, Kandelaria M KM; Kerr, Sarah E SE; Kocher, Jean-Pierre A JA; Beck, Scott A SA; Fernandez-Zapico, Martin E ME; Farrugia, Gianrico G; Lazaridis, Konstantinos N KN; McWilliams, Robert R RR

Publication Date: 2017-04-18

Variant appearance in text: ERBB2: A293T

PubMed Link: 28423702

Variant Present in the following documents:

• Main text
• oncotarget-08-27145.pdf

View BVdb publication page

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Annexin A1 Preferentially Predicts Poor Prognosis of Basal-Like Breast Cancer Patients by Activating mTOR-S6 Signaling.

Plos One

Bhardwaj, Anjana A; Ganesan, Nivetha N; Tachibana, Kazunoshin K; Rajapakshe, Kimal K; Albarracin, Constance T CT; Gunaratne, Preethi H PH; Coarfa, Cristian C; Bedrosian, Isabelle I

Publication Date: 2015

Variant appearance in text: HER2: A293T

PubMed Link: 26000884

Variant Present in the following documents:

• Main text
• pone.0127678.pdf

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The sensitivity of diffuse large B-cell lymphoma cell lines to histone deacetylase inhibitor-induced apoptosis is modulated by BCL-2 family protein activity.

Plos One

Thompson, Ryan C RC; Vardinogiannis, Iosif I; Gilmore, Thomas D TD

Publication Date: 2013

Variant appearance in text: HER2: A293T

PubMed Link: 23667527

Variant Present in the following documents:

• pone.0062822.pdf

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The HER4 cytoplasmic domain, but not its C terminus, inhibits mammary cell proliferation.

Molecular Endocrinology (Baltimore, Md.)

Feng, Shu-Mang SM; Sartor, Carolyn I CI; Hunter, Debra D; Zhou, Hong H; Yang, Xihui X; Caskey, Laura S LS; Dy, Ruth R; Muraoka-Cook, Rebecca S RS; Earp, H Shelton HS

Publication Date: 2007-08

Variant appearance in text: HER2: A293T

PubMed Link: 17505063

Variant Present in the following documents:

• Main text

View BVdb publication page

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