Integrated DNA and RNA Sequencing Reveals Drivers of Endocrine Resistance in Estrogen Receptor-Positive Breast Cancer.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Xia, Youli Y; He, Xiaping X; Renshaw, Lorna L; Martinez-Perez, Carlos C; Kay, Charlene C; Gray, Mark M; Meehan, James J; Parker, Joel S JS; Perou, Charles M CM; Carey, Lisa A LA; Dixon, J Michael JM; Turnbull, Arran A
Molecular landscape of TP53 mutations in breast cancer and their utility for predicting the response to HER-targeted therapy in HER2 amplification-positive and HER2 mutation-positive amplification-negative patients.
Stage-stratified molecular profiling of non-muscle-invasive bladder cancer enhances biological, clinical, and therapeutic insight.
Cell Reports. Medicine
Hurst, Carolyn D CD; Cheng, Guo G; Platt, Fiona M FM; Castro, Mauro A A MAA; Marzouka, Nour-Al-Dain S NS; Eriksson, Pontus P; Black, Emma V I EVI; Alder, Olivia O; Lawson, Andrew R J ARJ; Lindskrog, Sia V SV; Burns, Julie E JE; Jain, Sunjay S; Roulson, Jo-An JA; Brown, Joanne C JC; Koster, Jan J; Robertson, A Gordon AG; Martincorena, Inigo I; Dyrskjøt, Lars L; Höglund, Mattias M; Knowles, Margaret A MA
Circulating tumour DNA analysis to direct therapy in advanced breast cancer (plasmaMATCH): a multicentre, multicohort, phase 2a, platform trial.
The Lancet. Oncology
Turner, Nicholas C NC; Kingston, Belinda B; Kilburn, Lucy S LS; Kernaghan, Sarah S; Wardley, Andrew M AM; Macpherson, Iain R IR; Baird, Richard D RD; Roylance, Rebecca R; Stephens, Peter P; Oikonomidou, Olga O; Braybrooke, Jeremy P JP; Tuthill, Mark M; Abraham, Jacinta J; Winter, Matthew C MC; Bye, Hannah H; Hubank, Michael M; Gevensleben, Heidrun H; Cutts, Ros R; Snowdon, Claire C; Rea, Daniel D; Cameron, David D; Shaaban, Abeer A; Randle, Katrina K; Martin, Sue S; Wilkinson, Katie K; Moretti, Laura L; Bliss, Judith M JM; Ring, Alistair A
Phase and context shape the function of composite oncogenic mutations.
Nature
Gorelick, Alexander N AN; Sánchez-Rivera, Francisco J FJ; Cai, Yanyan Y; Bielski, Craig M CM; Biederstedt, Evan E; Jonsson, Philip P; Richards, Allison L AL; Vasan, Neil N; Penson, Alexander V AV; Friedman, Noah D ND; Ho, Yu-Jui YJ; Baslan, Timour T; Bandlamudi, Chaitanya C; Scaltriti, Maurizio M; Schultz, Nikolaus N; Lowe, Scott W SW; Reznik, Ed E; Taylor, Barry S BS
Contribution of allelic imbalance to colorectal cancer.
Nature Communications
Palin, Kimmo K; Pitkänen, Esa E; Turunen, Mikko M; Sahu, Biswajyoti B; Pihlajamaa, Päivi P; Kivioja, Teemu T; Kaasinen, Eevi E; Välimäki, Niko N; Hänninen, Ulrika A UA; Cajuso, Tatiana T; Aavikko, Mervi M; Tuupanen, Sari S; Kilpivaara, Outi O; van den Berg, Linda L; Kondelin, Johanna J; Tanskanen, Tomas T; Katainen, Riku R; Grau, Marta M; Rauanheimo, Heli H; Plaketti, Roosa-Maria RM; Taira, Aurora A; Sulo, Päivi P; Hartonen, Tuomo T; Dave, Kashyap K; Schmierer, Bernhard B; Botla, Sandeep S; Sokolova, Maria M; Vähärautio, Anna A; Gladysz, Kornelia K; Ongen, Halit H; Dermitzakis, Emmanouil E; Bramsen, Jesper Bertram JB; Ørntoft, Torben Falck TF; Andersen, Claus Lindbjerg CL; Ristimäki, Ari A; Lepistö, Anna A; Renkonen-Sinisalo, Laura L; Mecklin, Jukka-Pekka JP; Taipale, Jussi J; Aaltonen, Lauri A LA
Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.
Cell Reports
Way, Gregory P GP; Sanchez-Vega, Francisco F; La, Konnor K; Armenia, Joshua J; Chatila, Walid K WK; Luna, Augustin A; Sander, Chris C; Cherniack, Andrew D AD; Mina, Marco M; Ciriello, Giovanni G; Schultz, Nikolaus N; , ; Sanchez, Yolanda Y; Greene, Casey S CS
Clinical and molecular characterization of patients with cancer of unknown primary in the modern era.
Annals Of Oncology : Official Journal Of The European Society For Medical Oncology
Varghese, A M AM; Arora, A A; Capanu, M M; Camacho, N N; Won, H H HH; Zehir, A A; Gao, J J; Chakravarty, D D; Schultz, N N; Klimstra, D S DS; Ladanyi, M M; Hyman, D M DM; Solit, D B DB; Berger, M F MF; Saltz, L B LB