ERBB2 c.2257_2258delinsGC ;(p.K753A)

Variant ID: 17-37880213-AA-GC

NM_004448.2(ERBB2):c.2257_2258delinsGC;(p.K753A)

This variant was identified in 9 publications

View GRCh38 version.




Publications:


Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: ERBB2: K753A
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Nuclear ErbB2 represses DEPTOR transcription to inhibit autophagy in breast cancer cells.

Cell Death & Disease
Bi, Yanli Y; Gong, Longyuan L; Liu, Pengyuan P; Xiong, Xiufang X; Zhao, Yongchao Y
Publication Date: 2021-04-14

Variant appearance in text: ERBB2: K753A
PubMed Link: 33854045
Variant Present in the following documents:
  • Main text
  • 41419_2021_Article_3686.pdf
View BVdb publication page



Stimulation of Oncogene-Specific Tumor-Infiltrating T Cells through Combined Vaccine and αPD-1 Enable Sustained Antitumor Responses against Established HER2 Breast Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Crosby, Erika J EJ; Acharya, Chaitanya R CR; Haddad, Anthony-Fayez AF; Rabiola, Christopher A CA; Lei, Gangjun G; Wei, Jun-Ping JP; Yang, Xiao-Yi XY; Wang, Tao T; Liu, Cong-Xiao CX; Wagner, Kay U KU; Muller, William J WJ; Chodosh, Lewis A LA; Broadwater, Gloria G; Hyslop, Terry T; Shepherd, Jonathan H JH; Hollern, Daniel P DP; He, Xiaping X; Perou, Charles M CM; Chai, Shengjie S; Ashby, Benjamin K BK; Vincent, Benjamin G BG; Snyder, Joshua C JC; Force, Jeremy J; Morse, Michael A MA; Lyerly, Herbert K HK; Hartman, Zachary C ZC
Publication Date: 2020-09-01

Variant appearance in text: HER2: K753A
PubMed Link: 32732224
Variant Present in the following documents:
  • Main text
View BVdb publication page



Enhanced Immunogenicity of Engineered HER2 Antigens Potentiates Antitumor Immune Responses.

Vaccines
Jeon, Insu I; Lee, Jeong-Mi JM; Shin, Kwang-Soo KS; Kang, Taeseung T; Park, Myung Hwan MH; Seo, Hyungseok H; Song, Boyeong B; Koh, Choong-Hyun CH; Choi, Jeongwon J; Shin, Young Kee YK; Kim, Byung-Seok BS; Kang, Chang-Yuil CY
Publication Date: 2020-07-22

Variant appearance in text: HER2: K753A
PubMed Link: 32707803
Variant Present in the following documents:
  • Main text
  • vaccines-08-00403.pdf
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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: ERBB2: K753A
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
View BVdb publication page



Breast cancer vaccines delivered by dendritic cell-targeted lentivectors induce potent antitumor immune responses and protect mice from mammary tumor growth.

Vaccine
Bryson, Paul D PD; Han, Xiaolu X; Truong, Norman N; Wang, Pin P
Publication Date: 2017-10-13

Variant appearance in text: ERBB2: K753A
PubMed Link: 28916248
Variant Present in the following documents:
  • Main text
View BVdb publication page



Polyclonal HER2-specific antibodies induced by vaccination mediate receptor internalization and degradation in tumor cells.

Breast Cancer Research : Bcr
Ren, Xiu-Rong XR; Wei, Junping J; Lei, Gangjun G; Wang, Jiangbo J; Lu, Jiuyi J; Xia, Wenle W; Spector, Neil N; Barak, Larry S LS; Clay, Timothy M TM; Osada, Takuya T; Hamilton, Erika E; Blackwell, Kimberly K; Hobeika, Amy C AC; Morse, Michael A MA; Lyerly, H Kim HK; Chen, Wei W
Publication Date: 2012-06-07

Variant appearance in text: HER2: K753A
PubMed Link: 22676470
Variant Present in the following documents:
  • Main text
  • bcr3204.pdf
View BVdb publication page



Synergism from combined immunologic and pharmacologic inhibition of HER2 in vivo.

International Journal Of Cancer
Morse, Michael A MA; Wei, Junping J; Hartman, Zachary Z; Xia, Wenle W; Ren, Xiu-Rong XR; Lei, Gangjun G; Barry, William T WT; Osada, Takuya T; Hobeika, Amy C AC; Peplinski, Sharon S; Jiang, Haixiang H; Devi, Gayathri R GR; Chen, Wei W; Spector, Neil N; Amalfitano, Andrea A; Lyerly, H Kim HK; Clay, Timothy M TM
Publication Date: 2010-06-15

Variant appearance in text: HER2: K753A
PubMed Link: 19856307
Variant Present in the following documents:
  • Main text
View BVdb publication page



Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: implications for cancer therapy.

The Embo Journal
Citri, Ami A; Alroy, Iris I; Lavi, Sara S; Rubin, Chanan C; Xu, Wanping W; Grammatikakis, Nicolas N; Patterson, Cam C; Neckers, Len L; Fry, David W DW; Yarden, Yosef Y
Publication Date: 2002-05-15

Variant appearance in text: HER2: K753A
PubMed Link: 12006493
Variant Present in the following documents:
  • Main text
View BVdb publication page