Publications:

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: ERBB2: K753M

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: ERBB2: K753M

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

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Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations.

Cancer Cell

Pahuja, Kanika Bajaj KB; Nguyen, Thong T TT; Jaiswal, Bijay S BS; Prabhash, Kumar K; Thaker, Tarjani M TM; Senger, Kate K; Chaudhuri, Subhra S; Kljavin, Noelyn M NM; Antony, Aju A; Phalke, Sameer S; Kumar, Prasanna P; Mravic, Marco M; Stawiski, Eric W EW; Vargas, Derek D; Durinck, Steffen S; Gupta, Ravi R; Khanna-Gupta, Arati A; Trabucco, Sally E SE; Sokol, Ethan S ES; Hartmaier, Ryan J RJ; Singh, Ashish A; Chougule, Anuradha A; Trivedi, Vaishakhi V; Dutt, Amit A; Patil, Vijay V; Joshi, Amit A; Noronha, Vanita V; Ziai, James J; Banavali, Sripad D SD; Ramprasad, Vedam V; DeGrado, William F WF; Bueno, Raphael R; Jura, Natalia N; Seshagiri, Somasekar S

Publication Date: 2018-11-12

Variant appearance in text: HER2: K753M

PubMed Link: 30449325

Variant Present in the following documents:

• Main text

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Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480.

Oncotarget

Gudernova, Iva I; Balek, Lukas L; Varecha, Miroslav M; Kucerova, Jana Fialova JF; Kunova Bosakova, Michaela M; Fafilek, Bohumil B; Palusova, Veronika V; Uldrijan, Stjepan S; Trantirek, Lukas L; Krejci, Pavel P

Publication Date: 2017-12-12

Variant appearance in text: ERBB2: K753M

PubMed Link: 29312610

Variant Present in the following documents:

• Main text
• oncotarget-08-109319.pdf

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High cell-surface density of HER2 deforms cell membranes.

Nature Communications

Chung, Inhee I; Reichelt, Mike M; Shao, Lily L; Akita, Robert W RW; Koeppen, Hartmut H; Rangell, Linda L; Schaefer, Gabriele G; Mellman, Ira I; Sliwkowski, Mark X MX

Publication Date: 2016-09-07

Variant appearance in text: HER2: K753M

PubMed Link: 27599456

Variant Present in the following documents:

• Main text

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Resveratrol chemosensitizes HER-2-overexpressing breast cancer cells to docetaxel chemoresistance by inhibiting docetaxel-mediated activation of HER-2-Akt axis.

Cell Death Discovery

Vinod, B S BS; Nair, H H HH; Vijayakurup, V V; Shabna, A A; Shah, S S; Krishna, A A; Pillai, K S KS; Thankachan, S S; Anto, R J RJ

Publication Date: 2015

Variant appearance in text: HER-2: K753M

PubMed Link: 27551486

Variant Present in the following documents:

• Main text
• cddiscovery201561.pdf

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Identification of a novel HER3 activating mutation homologous to EGFR-L858R in lung cancer.

Oncotarget

Umelo, Ijeoma I; Noeparast, Amir A; Chen, Gang G; Renard, Marleen M; Geers, Caroline C; Vansteenkiste, Johan J; Giron, Philippe P; De Wever, Olivier O; Teugels, Erik E; De Grève, Jacques J

Publication Date: 2016-01-19

Variant appearance in text: HER2: K753M

PubMed Link: 26689995

Variant Present in the following documents:

• Main text
• oncotarget-07-3068.pdf

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PRP4K is a HER2-regulated modifier of taxane sensitivity.

Cell Cycle (Georgetown, Tex.)

Corkery, Dale P DP; Le Page, Cécile C; Meunier, Liliane L; Provencher, Diane D; Mes-Masson, Anne-Marie AM; Dellaire, Graham G

Publication Date: 2015

Variant appearance in text: HER2: K753M

PubMed Link: 25602630

Variant Present in the following documents:

• Main text
• kccy-14-07-1007775.pdf

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Structure-functional prediction and analysis of cancer mutation effects in protein kinases.

Computational And Mathematical Methods In Medicine

Dixit, Anshuman A; Verkhivker, Gennady M GM

Publication Date: 2014

Variant appearance in text: ERBB2: K753M

PubMed Link: 24817905

Variant Present in the following documents:

• CMMM2014-653487.pdf

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Identification of prolidase as a high affinity ligand of the ErbB2 receptor and its regulation of ErbB2 signaling and cell growth.

Cell Death & Disease

Yang, L L; Li, Y Y; Zhang, Y Y

Publication Date: 2014-05-08

Variant appearance in text: ERBB2: K753M

PubMed Link: 24810047

Variant Present in the following documents:

• Main text

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Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab.

Science Translational Medicine

Yonesaka, Kimio K; Zejnullahu, Kreshnik K; Okamoto, Isamu I; Satoh, Taroh T; Cappuzzo, Federico F; Souglakos, John J; Ercan, Dalia D; Rogers, Andrew A; Roncalli, Massimo M; Takeda, Masayuki M; Fujisaka, Yasuhito Y; Philips, Juliet J; Shimizu, Toshio T; Maenishi, Osamu O; Cho, Yonggon Y; Sun, Jason J; Destro, Annarita A; Taira, Koichi K; Takeda, Koji K; Okabe, Takafumi T; Swanson, Jeffrey J; Itoh, Hiroyuki H; Takada, Minoru M; Lifshits, Eugene E; Okuno, Kiyotaka K; Engelman, Jeffrey A JA; Shivdasani, Ramesh A RA; Nishio, Kazuto K; Fukuoka, Masahiro M; Varella-Garcia, Marileila M; Nakagawa, Kazuhiko K; Jänne, Pasi A PA

Publication Date: 2011-09-07

Variant appearance in text: ERBB2: K753M

PubMed Link: 21900593

Variant Present in the following documents:

• Main text

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