ERBB2 c.2263_2264delinsGC ;(p.L755A)

Variant ID: 17-37880219-TT-GC

NM_004448.2(ERBB2):c.2263_2264delinsGC;(p.L755A)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


Ado-tratuzumab emtansine beyond breast cancer: therapeutic role of targeting other HER2-positive cancers.

Frontiers In Molecular Biosciences
Zheng, Yang Y; Zou, Jiayu J; Sun, Chen C; Peng, Fu F; Peng, Cheng C
Publication Date: 2023

Variant appearance in text: HER2: L755A
PubMed Link: 37251081
Variant Present in the following documents:
  • Main text
  • fmolb-10-1165781.pdf
View BVdb publication page



Activity and mechanism of acquired resistance to tarloxotinib in HER2 mutant lung cancer: an in vitro study.

Translational Lung Cancer Research
Koga, Takamasa T; Suda, Kenichi K; Nishino, Masaya M; Fujino, Toshio T; Ohara, Shuta S; Hamada, Akira A; Soh, Junichi J; Tirunagaru, Vijaya V; Vellanki, Avanish A; Doebele, Robert C RC; Mitsudomi, Tetsuya T
Publication Date: 2021-08

Variant appearance in text: HER2: L755A
PubMed Link: 34584864
Variant Present in the following documents:
  • Main text
  • tlcr-10-08-3659.pdf
  • tlcr-10-08-3659-supplementary.pdf
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Targeted Sequencing Facilitated Diagnosis of an Uncommon Patient Harboring Both Multiple Primary and Intrapulmonary Metastatic Lung Cancer: A Case Report.

Oncotargets And Therapy
Li, Hefei H; Dong, Shaoyong S; Zhang, Duo D; Guo, Zhimin Z; Li, Ce C; Xiang, Jianxing J; Zou, Xiao X; Yan, Li L; Sun, Ying Y; Li, Wei W
Publication Date: 2021

Variant appearance in text: ERBB2: L755A
PubMed Link: 34079290
Variant Present in the following documents:
  • Main text
  • ott-14-3455.pdf
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Spectrum of driver mutations and clinical impact of circulating tumor DNA analysis in non-small cell lung cancer: Analysis of over 8000 cases.

Cancer
Mack, Philip C PC; Banks, Kimberly C KC; Espenschied, Carin R CR; Burich, Rebekah A RA; Zill, Oliver A OA; Lee, Christine E CE; Riess, Jonathan W JW; Mortimer, Stefanie A SA; Talasaz, AmirAli A; Lanman, Richard B RB; Gandara, David R DR
Publication Date: 2020-07-15

Variant appearance in text: ERBB2: L755A
PubMed Link: 32365229
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mutational landscape and characteristics of ERBB2 in non-small cell lung cancer.

Thoracic Cancer
Wei, Xue-Wu XW; Gao, Xin X; Zhang, Xu-Chao XC; Yang, Jin-Ji JJ; Chen, Zhi-Hong ZH; Wu, Yi-Long YL; Zhou, Qing Q
Publication Date: 2020-06

Variant appearance in text: ERBB2: L755A
PubMed Link: 32291971
Variant Present in the following documents:
  • Main text
  • TCA-11-1512.pdf
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[Association between the HER2 Gene Status and the Efficacy of First-line Pemetrexed Combined with Platinum Chemotherapy in Patients with Advanced Lung 
Adenocarcinoma].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Li, Panhua P; Li, Banban B; Shi, Yunshu Y; Zhang, Fengming F; Shen, Shujing S; Li, Xingya X
Publication Date: 2019-03-20

Variant appearance in text: HER2: L755A
PubMed Link: 30909992
Variant Present in the following documents:
  • Main text
  • zgfazz-22-3-137.pdf
View BVdb publication page



Ado-Trastuzumab Emtansine for Patients With HER2-Mutant Lung Cancers: Results From a Phase II Basket Trial.

Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology
Li, Bob T BT; Shen, Ronglai R; Buonocore, Darren D; Olah, Zachary T ZT; Ni, Ai A; Ginsberg, Michelle S MS; Ulaner, Gary A GA; Offin, Michael M; Feldman, Daniel D; Hembrough, Todd T; Cecchi, Fabiola F; Schwartz, Sarit S; Pavlakis, Nick N; Clarke, Stephen S; Won, Helen H HH; Brzostowski, Edyta B EB; Riely, Gregory J GJ; Solit, David B DB; Hyman, David M DM; Drilon, Alexander A; Rudin, Charles M CM; Berger, Michael F MF; Baselga, Jose J; Scaltriti, Maurizio M; Arcila, Maria E ME; Kris, Mark G MG
Publication Date: 2018-08-20

Variant appearance in text: HER2: L755A
PubMed Link: 29989854
Variant Present in the following documents:
  • Main text
View BVdb publication page



ERBB2-Mutated Metastatic Non-Small Cell Lung Cancer: Response and Resistance to Targeted Therapies.

Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer
Chuang, Jody C JC; Stehr, Henning H; Liang, Ying Y; Das, Millie M; Huang, Jane J; Diehn, Maximilian M; Wakelee, Heather A HA; Neal, Joel W JW
Publication Date: 2017-05

Variant appearance in text: HER2: L755A
PubMed Link: 28167203
Variant Present in the following documents:
  • Main text
View BVdb publication page