ERBB2 c.2303T>C ;(p.L768S)

Variant ID: 17-37880259-T-C

NM_004448.2(ERBB2):c.2303T>C;(p.L768S)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Clinical implication of genetic composition and molecular mechanism on treatment strategies of HER2-positive breast cancers.

Frontiers In Oncology
Chow, Christopher Y C CYC; Lie, Erich Ferdiansyah EF; Wu, Cheng-Hsun CH; Chow, Louis W C LWC
Publication Date: 2022

Variant appearance in text: HER2: L768S
PubMed Link: 36387174
Variant Present in the following documents:
  • Main text
  • fonc-12-964824.pdf
View BVdb publication page



Preclinical Characteristics of the Irreversible Pan-HER Kinase Inhibitor Neratinib Compared with Lapatinib: Implications for the Treatment of HER2-Positive and HER2-Mutated Breast Cancer.

Cancers
Collins, Denis M DM; Conlon, Neil T NT; Kannan, Srinivasaraghavan S; Verma, Chandra S CS; Eli, Lisa D LD; Lalani, Alshad S AS; Crown, John J
Publication Date: 2019-05-28

Variant appearance in text: HER2: L768S
PubMed Link: 31141894
Variant Present in the following documents:
  • Main text
  • cancers-11-00737.pdf
View BVdb publication page



Computational algorithms for in silico profiling of activating mutations in cancer.

Cellular And Molecular Life Sciences : Cmls
Jordan, E Joseph EJ; Patil, Keshav K; Suresh, Krishna K; Park, Jin H JH; Mosse, Yael P YP; Lemmon, Mark A MA; Radhakrishnan, Ravi R
Publication Date: 2019-07

Variant appearance in text: HER2: L768S
PubMed Link: 30982079
Variant Present in the following documents:
  • Main text
View BVdb publication page



Structural investigations on mechanism of lapatinib resistance caused by HER-2 mutants.

Plos One
Verma, Sharad S; Goyal, Sukriti S; Kumari, Anchala A; Singh, Aditi A; Jamal, Salma S; Grover, Abhinav A
Publication Date: 2018

Variant appearance in text: HER-2: L768S
PubMed Link: 29389942
Variant Present in the following documents:
  • Main text
  • pone.0190942.pdf
View BVdb publication page



Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Plos One
Holehouse, Alex S AS; Naegle, Kristen M KM
Publication Date: 2015

Variant appearance in text: rs56366519
PubMed Link: 26659599
Variant Present in the following documents:
  • pone.0144692.s002.xlsx, sheet 1
View BVdb publication page