ERBB2 c.2317G>C ;(p.V773L)

Variant ID: 17-37880988-G-C

NM_004448.2(ERBB2):c.2317G>C;(p.V773L)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Preclinical Characteristics of the Irreversible Pan-HER Kinase Inhibitor Neratinib Compared with Lapatinib: Implications for the Treatment of HER2-Positive and HER2-Mutated Breast Cancer.

Cancers
Collins, Denis M DM; Conlon, Neil T NT; Kannan, Srinivasaraghavan S; Verma, Chandra S CS; Eli, Lisa D LD; Lalani, Alshad S AS; Crown, John J
Publication Date: 2019-05-28

Variant appearance in text: HER2: V773L
PubMed Link: 31141894
Variant Present in the following documents:
  • Main text
  • cancers-11-00737.pdf
View BVdb publication page



Computational algorithms for in silico profiling of activating mutations in cancer.

Cellular And Molecular Life Sciences : Cmls
Jordan, E Joseph EJ; Patil, Keshav K; Suresh, Krishna K; Park, Jin H JH; Mosse, Yael P YP; Lemmon, Mark A MA; Radhakrishnan, Ravi R
Publication Date: 2019-07

Variant appearance in text: HER2: V773L
PubMed Link: 30982079
Variant Present in the following documents:
  • Main text
View BVdb publication page



Structural investigations on mechanism of lapatinib resistance caused by HER-2 mutants.

Plos One
Verma, Sharad S; Goyal, Sukriti S; Kumari, Anchala A; Singh, Aditi A; Jamal, Salma S; Grover, Abhinav A
Publication Date: 2018

Variant appearance in text: HER-2: V773L
PubMed Link: 29389942
Variant Present in the following documents:
  • Main text
  • pone.0190942.pdf
View BVdb publication page