ERBB2 c.2320_2322delinsTGGCTTGTA ;(p.M774delinsWLV)

Variant ID: 17-37880991-ATG-TGGCTTGTA

NM_004448.2(ERBB2):c.2320_2322delinsTGGCTTGTA;(p.M774delinsWLV)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


HER2-Altered Non-Small Cell Lung Cancer: Biology, Clinicopathologic Features, and Emerging Therapies.

Frontiers In Oncology
Yu, Xin X; Ji, Xianxiu X; Su, Chunxia C
Publication Date: 2022

Variant appearance in text: HER2: M774delinsWLV
PubMed Link: 35425713
Variant Present in the following documents:
  • Main text
  • fonc-12-860313.pdf
View BVdb publication page



Targeting HER2 in non-small-cell lung cancer (NSCLC): a glimpse of hope? An updated review on therapeutic strategies in NSCLC harbouring HER2 alterations.

Esmo Open
Riudavets, M M; Sullivan, I I; Abdayem, P P; Planchard, D D
Publication Date: 2021-10

Variant appearance in text: HER2: M774delinsWLV
PubMed Link: 34479034
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Mutation Variants and Co-Mutations as Genomic Modifiers of Response to Afatinib in HER2-Mutant Lung Adenocarcinoma.

The Oncologist
Fang, Wenfeng W; Zhao, Shen S; Liang, Ying Y; Yang, Yunpeng Y; Yang, Lin L; Dong, Xiaorong X; Zhang, Li L; Tang, Yong Y; Wang, Shoufeng S; Yang, Yang Y; Ma, Xiaoyan X; Wang, Minghui M; Wang, Wenjing W; Zhao, Songhui S; Wang, Kai K; Gao, Song S; Zhang, Li L
Publication Date: 2020-03

Variant appearance in text: HER2: M774delinsWLV
PubMed Link: 32162827
Variant Present in the following documents:
  • Main text
View BVdb publication page



Clinical evaluation of dacomitinib for the treatment of metastatic non-small cell lung cancer (NSCLC): current perspectives.

Drug Design, Development And Therapy
Lavacchi, Daniele D; Mazzoni, Francesca F; Giaccone, Giuseppe G
Publication Date: 2019

Variant appearance in text: HER2: M774delinsWLV
PubMed Link: 31564835
Variant Present in the following documents:
  • Main text
  • dddt-13-3187.pdf
View BVdb publication page



Efficacy of Afatinib in a Previously-Treated Patient with Non-Small Cell Lung Cancer Harboring HER2 Mutation: Case Report.

Journal Of Korean Medical Science
Park, Cheol Kyu CK; Hur, Jae Young JY; Choi, Chang Min CM; Kim, Tae Ok TO; Cho, Hyun Ju HJ; Shin, Hong Joon HJ; Lim, Jung Hwan JH; Choi, Yoo Duk YD; Kim, Young Chul YC; Oh, In Jae IJ
Publication Date: 2018-01-01

Variant appearance in text: HER2: M774delinsWLV
PubMed Link: 29215816
Variant Present in the following documents:
  • Main text
  • jkms-33-e7.pdf
View BVdb publication page



Response Heterogeneity of EGFR and HER2 Exon 20 Insertions to Covalent EGFR and HER2 Inhibitors.

Cancer Research
Kosaka, Takayuki T; Tanizaki, Junko J; Paranal, Raymond M RM; Endoh, Hideki H; Lydon, Christine C; Capelletti, Marzia M; Repellin, Claire E CE; Choi, Jihyun J; Ogino, Atsuko A; Calles, Antonio A; Ercan, Dalia D; Redig, Amanda J AJ; Bahcall, Magda M; Oxnard, Geoffrey R GR; Eck, Michael J MJ; Jänne, Pasi A PA
Publication Date: 2017-05-15

Variant appearance in text: HER2: M774delinsWLV
PubMed Link: 28363995
Variant Present in the following documents:
  • Main text
View BVdb publication page



Targeting HER2 aberrations as actionable drivers in lung cancers: phase II trial of the pan-HER tyrosine kinase inhibitor dacomitinib in patients with HER2-mutant or amplified tumors.

Annals Of Oncology : Official Journal Of The European Society For Medical Oncology
Kris, M G MG; Camidge, D R DR; Giaccone, G G; Hida, T T; Li, B T BT; O'Connell, J J; Taylor, I I; Zhang, H H; Arcila, M E ME; Goldberg, Z Z; Jänne, P A PA
Publication Date: 2015-07

Variant appearance in text: HER2: M774delinsWLV
PubMed Link: 25899785
Variant Present in the following documents:
  • Main text
View BVdb publication page