ERBB2 c.2327_2329del ;(p.G776del)

Variant ID: 17-37880995-CTGG-C

NM_004448.2(ERBB2):c.2327_2329del;(p.G776del)

This variant was identified in 9 publications

View GRCh38 version.




Publications:


Targeting the EGF receptor family in non-small cell lung cancer-increased complexity and future perspectives.

Cancer Biology & Medicine
Boch, Tobias T; Köhler, Jens J; Janning, Melanie M; Loges, Sonja S
Publication Date: 2022-12-05

Variant appearance in text: HER2: G776del
PubMed Link: 36476337
Variant Present in the following documents:
  • Main text
  • cbm-19-1543.pdf
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The circulating tumor DNA (ctDNA) alteration level predicts therapeutic response in metastatic breast cancer: Novel prognostic indexes based on ctDNA.

Breast (Edinburgh, Scotland)
Liu, Binliang B; Hu, Zheyu Z; Ran, Jialu J; Xie, Ning N; Tian, Can C; Tang, Yu Y; Ouyang, Quchang Q
Publication Date: 2022-10

Variant appearance in text: ERBB2: G776delins
PubMed Link: 35926241
Variant Present in the following documents:
  • mmc1.xlsx, sheet 1
View BVdb publication page



Activity and mechanism of acquired resistance to tarloxotinib in HER2 mutant lung cancer: an in vitro study.

Translational Lung Cancer Research
Koga, Takamasa T; Suda, Kenichi K; Nishino, Masaya M; Fujino, Toshio T; Ohara, Shuta S; Hamada, Akira A; Soh, Junichi J; Tirunagaru, Vijaya V; Vellanki, Avanish A; Doebele, Robert C RC; Mitsudomi, Tetsuya T
Publication Date: 2021-08

Variant appearance in text: HER2: G776delins
PubMed Link: 34584864
Variant Present in the following documents:
  • Main text
  • tlcr-10-08-3659.pdf
View BVdb publication page



A proteogenomic profile of early lung adenocarcinomas by protein co-expression network and genomic alteration analysis.

Scientific Reports
Nishimura, Toshihide T; Nakamura, Haruhiko H; Tan, Kien Thiam KT; Zhuo, De-Wei DW; Fujii, Kiyonaga K; Koizumi, Hirotaka H; Naruki, Saeko S; Takagi, Masayuki M; Furuya, Naoki N; Kato, Yasufumi Y; Chen, Shu-Jen SJ; Kato, Harubumi H; Saji, Hisashi H
Publication Date: 2020-08-12

Variant appearance in text: ERBB2: Gly776del
PubMed Link: 32788598
Variant Present in the following documents:
  • Main text
  • 41598_2020_Article_70578.pdf
View BVdb publication page



Pan-Cancer Landscape and Analysis of ERBB2 Mutations Identifies Poziotinib as a Clinically Active Inhibitor and Enhancer of T-DM1 Activity.

Cancer Cell
Robichaux, Jacqulyne P JP; Elamin, Yasir Y YY; Vijayan, R S K RSK; Nilsson, Monique B MB; Hu, Lemei L; He, Junqin J; Zhang, Fahao F; Pisegna, Marlese M; Poteete, Alissa A; Sun, Huiying H; Li, Shuai S; Chen, Ting T; Han, Han H; Negrao, Marcelo Vailati MV; Ahnert, Jordi Rodon JR; Diao, Lixia L; Wang, Jing J; Le, Xiuning X; Meric-Bernstam, Funda F; Routbort, Mark M; Roeck, Brent B; Yang, Zane Z; Raymond, Victoria M VM; Lanman, Richard B RB; Frampton, Garrett M GM; Miller, Vincent A VA; Schrock, Alexa B AB; Albacker, Lee A LA; Wong, Kwok-Kin KK; Cross, Jason B JB; Heymach, John V JV
Publication Date: 2019-10-14

Variant appearance in text: HER2: G776del
PubMed Link: 31588020
Variant Present in the following documents:
  • Main text
View BVdb publication page



Challenges of Providing Concordant Interpretation of Somatic Variants in Non-Small Cell Lung Cancer: A Multicenter Study.

Journal Of Cancer
Gao, Peng P; Zhang, Rui R; Li, Ziyang Z; Ding, Jiansheng J; Xie, Jiehong J; Li, Jinming J
Publication Date: 2019

Variant appearance in text: ERBB2: Gly776del
PubMed Link: 31205538
Variant Present in the following documents:
  • jcav10p1814.pdf
View BVdb publication page



Chemotherapy Modulates Endocrine Therapy-Related Resistance Mutations in Metastatic Breast Cancer.

Translational Oncology
Zhou, Dabo D; Ouyang, Quchang Q; Liu, Liping L; Liu, Jingyu J; Tang, Yu Y; Xiao, Mengjia M; Wang, Yikai Y; He, Qiongzhi Q; Hu, Zhe-Yu ZY
Publication Date: 2019-05

Variant appearance in text: ERBB2: G776delins
PubMed Link: 30893632
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Clinical and genetic risk factors for Fulvestrant treatment in post-menopause ER-positive advanced breast cancer patients.

Journal Of Translational Medicine
Liu, Jingyu J; Li, Jing J; Wang, Hui H; Wang, Yikai Y; He, Qiongzhi Q; Xia, Xuefeng X; Hu, Zhe-Yu ZY; Ouyang, Quchang Q
Publication Date: 2019-01-15

Variant appearance in text: ERBB2: G776delins
PubMed Link: 30646914
Variant Present in the following documents:
  • Main text
  • 12967_2018_Article_1734.pdf
View BVdb publication page



Overcoming resistance to HER2 inhibitors through state-specific kinase binding.

Nature Chemical Biology
Novotny, Chris J CJ; Pollari, Sirkku S; Park, Jin H JH; Lemmon, Mark A MA; Shen, Weijun W; Shokat, Kevan M KM
Publication Date: 2016-11

Variant appearance in text: HER2: G776del
PubMed Link: 27595329
Variant Present in the following documents:
  • Main text
  • nihms-796574.pdf
View BVdb publication page