Publications:

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Molecular pathways, resistance mechanisms and targeted interventions in non-small-cell lung cancer.

Molecular Biomedicine

Wang, Zixi Z; Xing, Yurou Y; Li, Bingjie B; Li, Xiaoyu X; Liu, Bin B; Wang, Yongsheng Y

Publication Date: 2022-12-12

Variant appearance in text: HER2: C805S

PubMed Link: 36508072

Variant Present in the following documents:

• Main text
• 43556_2022_Article_107.pdf

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Deciphering the Impact of HER2 Alterations on Non-Small-Cell Lung Cancer: From Biological Mechanisms to Therapeutic Approaches.

Journal Of Personalized Medicine

Bontoux, Christophe C; Benzaquen, Jonathan J; Hofman, Véronique V; Heeke, Simon S; Hannetel, Paul P; Capela-Brosseau-Laborde, Pierre P; Marquette, Charles-Hugo CH; Ilié, Marius M; Hofman, Paul P

Publication Date: 2022-10-04

Variant appearance in text: HER2: C805S

PubMed Link: 36294789

Variant Present in the following documents:

• Main text
• jpm-12-01651.pdf

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HER2-Altered Non-Small Cell Lung Cancer: Biology, Clinicopathologic Features, and Emerging Therapies.

Frontiers In Oncology

Yu, Xin X; Ji, Xianxiu X; Su, Chunxia C

Publication Date: 2022

Variant appearance in text: HER2: C805S

PubMed Link: 35425713

Variant Present in the following documents:

• Main text
• fonc-12-860313.pdf

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The efficacy of afatinib in patients with HER2 mutant non-small cell lung cancer: a meta-analysis.

Translational Cancer Research

Zhou, Niya N; Zhao, Jie J; Huang, Xiu X; Shen, Hui H; Li, Wen W; Xu, Zhihao Z; Xia, Yang Y

Publication Date: 2020-05

Variant appearance in text: HER2: C805S

PubMed Link: 35117726

Variant Present in the following documents:

• Main text
• tcr-09-05-3634.pdf

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HER2 Aberrations in Non-Small Cell Lung Cancer: From Pathophysiology to Targeted Therapy.

Pharmaceuticals (Basel, Switzerland)

Vathiotis, Ioannis A IA; Charpidou, Andriani A; Gavrielatou, Niki N; Syrigos, Konstantinos N KN

Publication Date: 2021-12-14

Variant appearance in text: HER2: C805S

PubMed Link: 34959700

Variant Present in the following documents:

• Main text
• pharmaceuticals-14-01300.pdf

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HER2 Aberrations in Non-Small Cell Lung Cancer: From Pathophysiology to Targeted Therapy.

Pharmaceuticals (Basel, Switzerland)

Vathiotis, Ioannis A IA; Charpidou, Andriani A; Gavrielatou, Niki N; Syrigos, Konstantinos N KN

Publication Date: 2021-12-14

Variant appearance in text: HER2: C805S

PubMed Link: 34959700

Variant Present in the following documents:

• Main text
• pharmaceuticals-14-01300.pdf

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Activity and mechanism of acquired resistance to tarloxotinib in HER2 mutant lung cancer: an in vitro study.

Translational Lung Cancer Research

Koga, Takamasa T; Suda, Kenichi K; Nishino, Masaya M; Fujino, Toshio T; Ohara, Shuta S; Hamada, Akira A; Soh, Junichi J; Tirunagaru, Vijaya V; Vellanki, Avanish A; Doebele, Robert C RC; Mitsudomi, Tetsuya T

Publication Date: 2021-08

Variant appearance in text: HER2: C805S

PubMed Link: 34584864

Variant Present in the following documents:

• Main text
• tlcr-10-08-3659-supplementary.pdf
• tlcr-10-08-3659.pdf
• tlcr-10-08-3659-prf.pdf

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Tackling Drug Resistance in EGFR Exon 20 Insertion Mutant Lung Cancer.

Pharmacogenomics And Personalized Medicine

Pacini, Laura L; Jenks, Andrew D AD; Vyse, Simon S; Wilding, Christopher P CP; Arthur, Amani A; Huang, Paul H PH

Publication Date: 2021

Variant appearance in text: HER2: C805S

PubMed Link: 33727854

Variant Present in the following documents:

• Main text
• pgpm-14-301.pdf

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[Chinese Expert Consensus on Next Generation Sequencing Diagnosis 
for Non-small Cell Lung Cancer (2020 Edition)].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer

,

Publication Date: 2020-09-20

Variant appearance in text: ERBB2: C805S

PubMed Link: 32957170

Variant Present in the following documents:

• Main text
• zgfazz-23-9-741.pdf

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Early-onset colorectal cancer: A distinct entity with unique genetic features.

Oncology Letters

Jiang, Dan D; Shu, Chang C; Lei, Chuanfen C; Wan, Ying Y; Sun, Linyong L

Publication Date: 2020-10

Variant appearance in text: ERBB2: C805S

PubMed Link: 32774506

Variant Present in the following documents:

• Main text
• ol-20-04-11894.pdf

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Genomic alterations of ERBB receptors in cancer: clinical implications.

Oncotarget

Mishra, Rosalin R; Hanker, Ariella B AB; Garrett, Joan T JT

Publication Date: 2017-12-26

Variant appearance in text: HER2: C805S

PubMed Link: 29371993

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• Main text

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Activating HER2 mutations as emerging targets in multiple solid cancers.

Esmo Open

Connell, Claire M CM; Doherty, Gary J GJ

Publication Date: 2017

Variant appearance in text: HER2: C805S

PubMed Link: 29209536

Variant Present in the following documents:

• Main text
• esmoopen-2017-000279.pdf

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Response Heterogeneity of EGFR and HER2 Exon 20 Insertions to Covalent EGFR and HER2 Inhibitors.

Cancer Research

Kosaka, Takayuki T; Tanizaki, Junko J; Paranal, Raymond M RM; Endoh, Hideki H; Lydon, Christine C; Capelletti, Marzia M; Repellin, Claire E CE; Choi, Jihyun J; Ogino, Atsuko A; Calles, Antonio A; Ercan, Dalia D; Redig, Amanda J AJ; Bahcall, Magda M; Oxnard, Geoffrey R GR; Eck, Michael J MJ; Jänne, Pasi A PA

Publication Date: 2017-05-15

Variant appearance in text: HER2: C805S

PubMed Link: 28363995

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• Main text

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The phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Vivanco, Igor I; Rohle, Daniel D; Versele, Matthias M; Iwanami, Akio A; Kuga, Daisuke D; Oldrini, Barbara B; Tanaka, Kazuhiro K; Dang, Julie J; Kubek, Sara S; Palaskas, Nicolaos N; Hsueh, Teli T; Evans, Michael M; Mulholland, David D; Wolle, Daniel D; Rajasekaran, Sigrid S; Rajasekaran, Ayyappan A; Liau, Linda M LM; Cloughesy, Timothy F TF; Dikic, Ivan I; Brennan, Cameron C; Wu, Hong H; Mischel, Paul S PS; Perera, Timothy T; Mellinghoff, Ingo K IK

Publication Date: 2010-04-06

Variant appearance in text: HER2: Cys805Ser

PubMed Link: 20308550

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