Publications:

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The Role of HER2 Status in the Biliary Tract Cancers.

Cancers

Ayasun, Ruveyda R; Ozer, Muhammet M; Sahin, Ilyas I

Publication Date: 2023-05-05

Variant appearance in text: HER2: H878Y

PubMed Link: 37174094

Variant Present in the following documents:

• Main text
• cancers-15-02628.pdf

View BVdb publication page

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Antitumour activity of neratinib in patients with HER2-mutant advanced biliary tract cancers.

Nature Communications

Harding, James J JJ; Piha-Paul, Sarina A SA; Shah, Ronak H RH; Murphy, Jessica J JJ; Cleary, James M JM; Shapiro, Geoffrey I GI; Quinn, David I DI; Braña, Irene I; Moreno, Victor V; Borad, Mitesh M; Loi, Sherene S; Spanggaard, Iben I; Park, Haeseong H; Ford, James M JM; Arnedos, Mónica M; Stemmer, Salomon M SM; de la Fouchardiere, Christelle C; Fountzilas, Christos C; Zhang, Jie J; DiPrimeo, Daniel D; Savin, Casey C; Duygu Selcuklu, S S; Berger, Michael F MF; Eli, Lisa D LD; Meric-Bernstam, Funda F; Jhaveri, Komal K; Solit, David B DB; Abou-Alfa, Ghassan K GK

Publication Date: 2023-02-06

Variant appearance in text: ERBB2: H878Y

PubMed Link: 36746967

Variant Present in the following documents:

• 41467_2023_36399_MOESM3_ESM.xlsx, sheet 5
• 41467_2023_36399_MOESM1_ESM.pdf
• 41467_2023_Article_36399.pdf

View BVdb publication page

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Molecular Landscape of ERBB2 Alterations in 14,956 Solid Tumors.

Pathology Oncology Research : Por

Wang, Hao H; Miao, Ji J; Wen, Yazhou Y; Xia, Xihua X; Chen, Yanan Y; Huang, Mengli M; Chen, Shiqing S; Zhao, Zhengyi Z; Zhang, Yuzi Y; Chen, Chunzhu C; Zhu, Xinhua X

Publication Date: 2022

Variant appearance in text: ERBB2: H878Y

PubMed Link: 35911441

Variant Present in the following documents:

• Main text
• pore-28-1610360.pdf

View BVdb publication page

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Poziotinib Inhibits HER2-Mutant-Driven Therapeutic Resistance and Multiorgan Metastasis in Breast Cancer.

Cancer Research

Kalra, Rashi R; Chen, Ching Hui CH; Wang, Junkai J; Salam, Ahmad Bin AB; Dobrolecki, Lacey E LE; Lewis, Alaina A; Sallas, Christina C; Yates, Clayton C CC; Gutierrez, Carolina C; Karanam, Balasubramanyam B; Anurag, Meenakshi M; Lim, Bora B; Ellis, Matthew J MJ; Kavuri, Shyam M SM

Publication Date: 2022-08-16

Variant appearance in text: HER2: H878Y

PubMed Link: 35736563

Variant Present in the following documents:

• can-21-3106_supplementary_data_suppst1.xlsx, sheet 2

View BVdb publication page

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Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging

Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M

Publication Date: 2022-05-25

Variant appearance in text: ERBB2: 2632C>T; H878Y

PubMed Link: 35613927

Variant Present in the following documents:

• aging-14-204101-s004.xlsx, sheet 1

View BVdb publication page

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Molecular landscape of TP53 mutations in breast cancer and their utility for predicting the response to HER-targeted therapy in HER2 amplification-positive and HER2 mutation-positive amplification-negative patients.

Cancer Medicine

Liu, Binliang B; Yi, Zongbi Z; Guan, Yanfang Y; Ouyang, Quchang Q; Li, Chunxiao C; Guan, Xiuwen X; Lv, Dan D; Li, Lixi L; Zhai, Jingtong J; Qian, Haili H; Xu, Binghe B; Ma, Fei F; Zeng, Yixin Y

Publication Date: 2022-07

Variant appearance in text: ERBB2: 2632C>T; H878Y

PubMed Link: 35393784

Variant Present in the following documents:

• CAM4-11-2767-s001.xlsx, sheet 1

View BVdb publication page

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Understanding the activating mechanism of the immune system against COVID-19 by Traditional Indian Medicine: Network pharmacology approach.

Advances In Protein Chemistry And Structural Biology

Thirumal Kumar, D D; Shree Devi, M S MS; Udhaya Kumar, S S; Sherlin, Annie A; Mathew, Aishwarya A; Lakshmipriya, M M; Sathiyarajeswaran, P P; Gnanasambandan, R R; Siva, R R; Magesh, R R; George Priya Doss, C C

Publication Date: 2022

Variant appearance in text: ERBB2: H878Y

PubMed Link: 35305722

Variant Present in the following documents:

• mmc09-01-9780323992275.pdf

View BVdb publication page

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Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications

Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L

Publication Date: 2022-03-10

Variant appearance in text: ERBB2: 2632C>T; H878Y

PubMed Link: 35273153

Variant Present in the following documents:

• 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: ERBB2: H878Y

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Efficacy and Resistance of Afatinib in Chinese Non-Small Cell Lung Cancer Patients With HER2 Alterations: A Multicenter Retrospective Study.

Frontiers In Oncology

Song, Zhengbo Z; Lv, Dongqing D; Chen, Shiqing S; Huang, Jianhui J; Wang, Liping L; Xu, Shuguang S; Chen, Huafei H; Wang, Guoqiang G; Lin, Quan Q

Publication Date: 2021

Variant appearance in text: HER2: H878Y

PubMed Link: 34026634

Variant Present in the following documents:

• Main text
• fonc-11-657283.pdf

View BVdb publication page

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: ERBB2: 2632C>T; H878Y

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: ERBB2: 2632C>T; H878Y

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
• 41467_2020_20162_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Genetic aberrations in Chinese pancreatic cancer patients and their association with anatomic location and disease outcomes.

Cancer Medicine

Lu, Junliang J; Yu, Ruoying R; Liu, Rui R; Liang, Xiaolong X; Sun, Jian J; Zhang, Hui H; Wu, Huanwen H; Zhang, Zhiwen Z; Shao, Yang W YW; Guo, Junchao J; Liang, Zhiyong Z

Publication Date: 2021-02

Variant appearance in text: ERBB2: H878Y

PubMed Link: 33350171

Variant Present in the following documents:

• Main text
• CAM4-10-933.pdf
• CAM4-10-933-s001.xlsx, sheet 1

View BVdb publication page

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Predictive Biomarkers for Immune Checkpoint Inhibitors in Metastatic Breast Cancer.

Cancer Medicine

Sivapiragasam, Abirami A; Ashok Kumar, Prashanth P; Sokol, Ethan S ES; Albacker, Lee A LA; Killian, Jonathan K JK; Ramkissoon, Shakti H SH; Huang, Richard S P RSP; Severson, Eric A EA; Brown, Charlotte A CA; Danziger, Natalie N; McGregor, Kimberly K; Ross, Jeffrey S JS

Publication Date: 2021-01

Variant appearance in text: ERBB2: H878Y

PubMed Link: 33314633

Variant Present in the following documents:

• CAM4-10-53-s003.xlsx, sheet 1

View BVdb publication page

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Molecular landscape and efficacy of HER2-targeted therapy in patients with HER2-mutated metastatic breast cancer.

Npj Breast Cancer

Yi, Zongbi Z; Rong, Guohua G; Guan, Yanfang Y; Li, Jin J; Chang, Lianpeng L; Li, Hui H; Liu, Binliang B; Wang, Wenna W; Guan, Xiuwen X; Ouyang, Quchang Q; Li, Lixi L; Zhai, Jingtong J; Li, Chunxiao C; Li, Lifeng L; Xia, Xuefeng X; Yang, Ling L; Qian, Haili H; Yi, Xin X; Xu, Binghe B; Ma, Fei F

Publication Date: 2020

Variant appearance in text: ERBB2: 2632C>T; H878Y

PubMed Link: 33145402

Variant Present in the following documents:

• 41523_2020_201_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine

Li, Jiaping J; Jiang, Wei W; Wei, Jinwang J; Zhang, Jianwei J; Cai, Linbo L; Luo, Minjie M; Wang, Zhan Z; Sun, Wending W; Wang, Shengzhou S; Wang, Chen C; Dai, Chun C; Liu, Jun J; Wang, Guan G; Wang, Jiping J; Xu, Qiang Q; Deng, Yanhong Y

Publication Date: 2020-08-01

Variant appearance in text: ERBB2: H878Y

PubMed Link: 32738923

Variant Present in the following documents:

• 12967_2020_2449_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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A step towards personalizing next line therapy for resected pancreatic and related cancer patients: A single institution's experience.

Surgical Oncology

Lowder, Cinthya Y CY; Dhir, Teena T; Goetz, Austin B AB; Thomsett, Henry L HL; Bender, Joseph J; Tatarian, Talar T; Madhavan, Subha S; Petricoin, Emanuel F EF; Blais, Edik E; Lavu, Harish H; Winter, Jordan M JM; Posey, James J; Brody, Jonathan R JR; Pishvaian, Michael J MJ; Yeo, Charles J CJ

Publication Date: 2020-06

Variant appearance in text: HER2: H878Y

PubMed Link: 32561076

Variant Present in the following documents:

• Main text
• nihms-1621334.pdf

View BVdb publication page

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Phosphoinositide specific phospholipase Cγ1 inhibition-driven autophagy caused cell death in human lung adenocarcinoma A549 cells in vivo and in vitro.

International Journal Of Biological Sciences

Lu, Xiaohong X; Fu, Haijing H; Chen, Rui R; Wang, Yue Y; Zhan, Yanyan Y; Song, Gang G; Hu, Tianhui T; Xia, Chun C; Tian, Xuemei X; Zhang, Bing B

Publication Date: 2020

Variant appearance in text: HER2: H878Y

PubMed Link: 32210730

Variant Present in the following documents:

• ijbsv16p1427.pdf

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: ERBB2: H878Y

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 11
• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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Development and validation of a targeted gene sequencing panel for application to disparate cancers.

Scientific Reports

McCabe, Mark J MJ; Gauthier, Marie-Emilie A MA; Chan, Chia-Ling CL; Thompson, Tanya J TJ; De Sousa, Sunita M C SMC; Puttick, Clare C; Grady, John P JP; Gayevskiy, Velimir V; Tao, Jiang J; Ying, Kevin K; Cipponi, Arcadi A; Deng, Niantao N; Swarbrick, Alex A; Thomas, Melissa L ML; Lord, Reginald V RV; Johns, Amber L AL; Kohonen-Corish, Maija M; O'Toole, Sandra A SA; Clark, Jonathan J; Mueller, Simon A SA; Gupta, Ruta R; McCormack, Ann I AI; Dinger, Marcel E ME; Cowley, Mark J MJ; ,

Publication Date: 2019-11-19

Variant appearance in text: ERBB2: 2632C>T; H878Y

PubMed Link: 31745186

Variant Present in the following documents:

• 41598_2019_52000_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Validation and Clinical Applications of a Comprehensive Next Generation Sequencing System for Molecular Characterization of Solid Cancer Tissues.

Frontiers In Molecular Biosciences

Dehghani, Mehdi M; Rosenblatt, Kevin P KP; Li, Lei L; Rakhade, Mrudula M; Amato, Robert J RJ

Publication Date: 2019

Variant appearance in text: ERBB2: His878Tyr

PubMed Link: 31681791

Variant Present in the following documents:

• Data_Sheet_5.pdf

View BVdb publication page

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The Mutational Landscape of Pancreatic and Liver Cancers, as Represented by Circulating Tumor DNA.

Frontiers In Oncology

Rice, Alistair A; Del Rio Hernandez, Armando A

Publication Date: 2019

Variant appearance in text: ERBB2: H878Y

PubMed Link: 31608239

Variant Present in the following documents:

• Main text
• fonc-09-00952.pdf

View BVdb publication page

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: ERBB2: H878Y

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

View BVdb publication page

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Targeted mutation detection in breast cancer using MammaSeq™.

Breast Cancer Research : Bcr

Smith, Nicholas G NG; Gyanchandani, Rekha R; Shah, Osama S OS; Gurda, Grzegorz T GT; Lucas, Peter C PC; Hartmaier, Ryan J RJ; Brufsky, Adam M AM; Puhalla, Shannon S; Bahreini, Amir A; Kota, Karthik K; Wald, Abigail I AI; Nikiforov, Yuri E YE; Nikiforova, Marina N MN; Oesterreich, Steffi S; Lee, Adrian V AV

Publication Date: 2019-02-08

Variant appearance in text: ERBB2: H878Y

PubMed Link: 30736836

Variant Present in the following documents:

• 13058_2019_1102_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Correction: Tumor driven by gain-of-function HER2 H878Y mutant is highly sensitive to HER2 inhibitor.

Oncotarget

Hu, Zexi Z; Hu, Yong Y; Liu, Xicheng X; Xi, Rongwen R; Zhang, Aiqun A; Liu, Deruo D; Xie, Qiang Q; Chen, Liang L

Publication Date: 2018-10-16

Variant appearance in text: HER2: H878Y

PubMed Link: 30443295

Variant Present in the following documents:

• oncotarget-09-35283.pdf

View BVdb publication page

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Validation of the Oncomine™ focus panel for next-generation sequencing of clinical tumour samples.

Virchows Archiv : An International Journal Of Pathology

Williams, Hannah L HL; Walsh, Kathy K; Diamond, Austin A; Oniscu, Anca A; Deans, Zandra C ZC

Publication Date: 2018-10

Variant appearance in text: ERBB2: 2632C>T; H878Y

PubMed Link: 30105577

Variant Present in the following documents:

• 428_2018_2411_MOESM2_ESM.xlsx, sheet 1
• 428_2018_2411_MOESM3_ESM.xlsx, sheet 1
• 428_2018_2411_MOESM1_ESM.xlsx, sheet 4
• 428_2018_2411_MOESM1_ESM.xlsx, sheet 3
• 428_2018_2411_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Fibroblast growth factor receptor 3 (FGFR3) aberrations in muscle-invasive urothelial carcinoma.

Bmc Urology

Kim, Young Saing YS; Kim, Kyung K; Kwon, Ghee-Young GY; Lee, Su Jin SJ; Park, Se Hoon SH

Publication Date: 2018-07-31

Variant appearance in text: ERBB2: 2632C>T; H878Y

PubMed Link: 30064409

Variant Present in the following documents:

• 12894_2018_380_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Frequency, impact and a preclinical study of novel ERBB gene family mutations in HER2-positive breast cancer.

Therapeutic Advances In Medical Oncology

Elster, Naomi N; Toomey, Sinead S; Fan, Yue Y; Cremona, Mattia M; Morgan, Clare C; Weiner Gorzel, Karolina K; Bhreathnach, Una U; Milewska, Malgorzata M; Murphy, Madeline M; Madden, Stephen S; Naidoo, Jarushka J; Fay, Joanna J; Kay, Elaine E; Carr, Aoife A; Kennedy, Sean S; Furney, Simon S; Mezynski, Janusz J; Breathhnach, Oscar O; Morris, Patrick P; Grogan, Liam L; Hill, Arnold A; Kennedy, Susan S; Crown, John J; Gallagher, William W; Hennessy, Bryan B; Eustace, Alex A

Publication Date: 2018

Variant appearance in text: HER2: H878Y

PubMed Link: 30023006

Variant Present in the following documents:

• Main text
• 10.1177_1758835918778297.pdf

View BVdb publication page

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Feasibility study of cancer genome alterations identified by next generation sequencing: ABC study.

Japanese Journal Of Clinical Oncology

Naito, Yoichi Y; Takahashi, Hideaki H; Shitara, Kohei K; Okamoto, Wataru W; Bando, Hideaki H; Kuwata, Takeshi T; Kuboki, Yasutoshi Y; Matsumoto, Shingo S; Miki, Izumi I; Yamanaka, Takeharu T; Watanabe, Atsushi A; Kojima, Motohiro M

Publication Date: 2018-06-01

Variant appearance in text: ERBB2: 2632C>T; H878Y

PubMed Link: 29659903

Variant Present in the following documents:

• hyy052supplementaltable1ionver1.xls, sheet 1

View BVdb publication page

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Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3.

Cancer

Ross, Jeffrey S JS; Fakih, Marwan M; Ali, Siraj M SM; Elvin, Julia A JA; Schrock, Alexa B AB; Suh, James J; Vergilio, Jo-Anne JA; Ramkissoon, Shakti S; Severson, Eric E; Daniel, Sugganth S; Fabrizio, David D; Frampton, Garrett G; Sun, James J; Miller, Vincent A VA; Stephens, Philip J PJ; Gay, Laurie M LM

Publication Date: 2018-04-01

Variant appearance in text: ERBB2: H878Y

PubMed Link: 29338072

Variant Present in the following documents:

• Main text

View BVdb publication page

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Activating HER2 mutations as emerging targets in multiple solid cancers.

Esmo Open

Connell, Claire M CM; Doherty, Gary J GJ

Publication Date: 2017

Variant appearance in text: HER2: H878Y

PubMed Link: 29209536

Variant Present in the following documents:

• Main text
• esmoopen-2017-000279.pdf

View BVdb publication page

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Molecular Characterization of Urothelial Carcinoma of the Bladder and Upper Urinary Tract.

Translational Oncology

Lee, Ji Yun JY; Kim, Kyung K; Sung, Hyun Hwan HH; Jeon, Hwang Gyun HG; Jeong, Byong Chang BC; Seo, Seong Il SI; Jeon, Seong Soo SS; Lee, Hyun Moo HM; Choi, Han-Yong HY; Kwon, Ghee-Young GY; Kim, Kyoung-Mee KM; Lee, Jeeyun J; Lim, Ho Yeong HY; Park, Se Hoon SH

Publication Date: 2018-02

Variant appearance in text: ERBB2: 2632C>T; H878Y

PubMed Link: 29161613

Variant Present in the following documents:

• mmc1.xlsx, sheet 1

View BVdb publication page

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HER2 aberrations and heterogeneity in cancers of the digestive system: Implications for pathologists and gastroenterologists.

World Journal Of Gastroenterology

Fusco, Nicola N; Bosari, Silvano S

Publication Date: 2016-09-21

Variant appearance in text: HER2: 2632C>T

PubMed Link: 27672288

Variant Present in the following documents:

• Main text
• WJG-22-7926.pdf

View BVdb publication page

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PredictSNP2: A Unified Platform for Accurately Evaluating SNP Effects by Exploiting the Different Characteristics of Variants in Distinct Genomic Regions.

Plos Computational Biology

Bendl, Jaroslav J; Musil, Miloš M; Štourač, Jan J; Zendulka, Jaroslav J; Damborský, Jiří J; Brezovský, Jan J

Publication Date: 2016-05

Variant appearance in text: ERBB2: H878Y

PubMed Link: 27224906

Variant Present in the following documents:

• pcbi.1004962.s005.xlsx, sheet 1

View BVdb publication page

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Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples.

Journal Of Translational Medicine

Dallol, Ashraf A; Buhmeida, Abdelbaset A; Al-Ahwal, Mahmoud Shaheen MS; Al-Maghrabi, Jaudah J; Bajouh, Osama O; Al-Khayyat, Shadi S; Alam, Rania R; Abusanad, Atlal A; Turki, Rola R; Elaimi, Aisha A; Alhadrami, Hani A HA; Abuzenadah, Mohammed M; Banni, Huda H; Al-Qahtani, Mohammed H MH; Abuzenadah, Adel M AM

Publication Date: 2016-05-04

Variant appearance in text: ERBB2: His878Tyr

PubMed Link: 27146902

Variant Present in the following documents:

• Main text
• 12967_2016_Article_878.pdf

View BVdb publication page

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Mutational profiling of brain metastasis from breast cancer: matched pair analysis of targeted sequencing between brain metastasis and primary breast cancer.

Oncotarget

Lee, Ji Yun JY; Park, Kyunghee K; Lim, Sung Hee SH; Kim, Hae Su HS; Yoo, Kwai Han KH; Jung, Ki Sun KS; Song, Haa-Na HN; Hong, Mineui M; Do, In-Gu IG; Ahn, TaeJin T; Lee, Se Kyung SK; Bae, Soo Youn SY; Kim, Seok Won SW; Lee, Jeong Eon JE; Nam, Seok Jin SJ; Kim, Duk-Hwan DH; Jung, Hae Hyun HH; Kim, Ji-Yeon JY; Ahn, Jin Seok JS; Im, Young-Hyuck YH; Park, Yeon Hee YH

Publication Date: 2015-12-22

Variant appearance in text: ERBB2: 2632C>T; H878Y

PubMed Link: 26527317

Variant Present in the following documents:

• oncotarget-06-43731-s002.xlsx, sheet 1

View BVdb publication page

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Tumor driven by gain-of-function HER2 H878Y mutant is highly sensitive to HER2 inhibitor.

Oncotarget

Hu, Zexi Z; Hu, Yong Y; Liu, Xicheng X; Xi, Rongwen R; Zhang, Aiqun A; Liu, Deruo D; Xie, Qiang Q; Chen, Liang L

Publication Date: 2015-10-13

Variant appearance in text: HER2: H878Y

PubMed Link: 26375550

Variant Present in the following documents:

• Main text

View BVdb publication page

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Patient-derived cell models as preclinical tools for genome-directed targeted therapy.

Oncotarget

Lee, Ji Yun JY; Kim, Sun Young SY; Park, Charny C; Kim, Nayoung K D NK; Jang, Jiryeon J; Park, Kyunghee K; Yi, Jun Ho JH; Hong, Mineui M; Ahn, Taejin T; Rath, Oliver O; Schueler, Julia J; Kim, Seung Tae ST; Do, In-Gu IG; Lee, Sujin S; Park, Se Hoon SH; Ji, Yong Ick YI; Kim, Dukwhan D; Park, Joon Oh JO; Park, Young Suk YS; Kang, Won Ki WK; Kim, Kyoung-Mee KM; Park, Woong-Yang WY; Lim, Ho Yeong HY; Lee, Jeeyun J

Publication Date: 2015-09-22

Variant appearance in text: ERBB2: 2632C>T; H878Y

PubMed Link: 26296973

Variant Present in the following documents:

• oncotarget-06-25619-s003.xls, sheet 1

View BVdb publication page

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Molecular characterization of patients with pathologic complete response or early failure after neoadjuvant chemotherapy for locally advanced breast cancer using next generation sequencing and nCounter assay.

Oncotarget

Park, Kyunghee K; Choi, Moon Ki MK; Jung, Hae Hyun HH; Do, In-Gu IG; Lee, Kwang Hee KH; Ahn, TaeJin T; Kil, Won Ho WH; Kim, Seok Won SW; Lee, Jeong Eon JE; Nam, Seok Jin SJ; Kim, Duk-Hwan DH; Ahn, Jin Seok JS; Im, Young-Hyuck YH; Park, Yeon Hee YH

Publication Date: 2015-09-15

Variant appearance in text: ERBB2: 2632C>T; H878Y

PubMed Link: 26009992

Variant Present in the following documents:

• oncotarget-06-24499-s002.xlsx, sheet 1

View BVdb publication page

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Phosphorylation of mutationally introduced tyrosine in the activation loop of HER2 confers gain-of-function activity.

Plos One

Hu, Zexi Z; Wan, Xiaobo X; Hao, Rui R; Zhang, Heng H; Li, Li L; Li, Lin L; Xie, Qiang Q; Wang, Peng P; Gao, Yibo Y; Chen, She S; Wei, Min M; Luan, Zhidong Z; Zhang, Aiqun A; Huang, Niu N; Chen, Liang L

Publication Date: 2015

Variant appearance in text: HER2: H878Y

PubMed Link: 25853726

Variant Present in the following documents:

• Main text
• pone.0123623.pdf

View BVdb publication page

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High-throughput sequencing and copy number variation detection using formalin fixed embedded tissue in metastatic gastric cancer.

Plos One

Kim, Seokhwi S; Lee, Jeeyun J; Hong, Min Eui ME; Do, In-Gu IG; Kang, So Young SY; Ha, Sang Yun SY; Kim, Seung Tae ST; Park, Se Hoon SH; Kang, Won Ki WK; Choi, Min-Gew MG; Lee, Jun Ho JH; Sohn, Tae Sung TS; Bae, Jae Moon JM; Kim, Sung S; Kim, Duk-Hwan DH; Kim, Kyoung-Mee KM

Publication Date: 2014

Variant appearance in text: ERBB2: 2632C>T; H878Y

PubMed Link: 25372287

Variant Present in the following documents:

• pone.0111693.s003.xls, sheet 1

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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

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PubMed Link: 25348012

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• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

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Panel based MALDI-TOF tumour profiling is a sensitive method for detecting mutations in clinical non small cell lung cancer tumour.

Plos One

Sherwood, James L JL; Müller, Susanne S; Orr, Maria C M MC; Ratcliffe, Marianne J MJ; Walker, Jill J

Publication Date: 2014

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PubMed Link: 24956168

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• pone.0100566.pdf

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Assessment of computational methods for predicting the effects of missense mutations in human cancers.

Bmc Genomics

Gnad, Florian F; Baucom, Albion A; Mukhyala, Kiran K; Manning, Gerard G; Zhang, Zemin Z

Publication Date: 2013

Variant appearance in text: ERBB2: H878Y

PubMed Link: 23819521

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• 1471-2164-14-S3-S7-S1.xlsx, sheet 1

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Differential sensitivity of ERBB2 kinase domain mutations towards lapatinib.

Plos One

Kancha, Rama Krishna RK; von Bubnoff, Nikolas N; Bartosch, Natalie N; Peschel, Christian C; Engh, Richard A RA; Duyster, Justus J

Publication Date: 2011

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PubMed Link: 22046346

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• pone.0026760.pdf

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Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research

Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C

Publication Date: 2011-09-01

Variant appearance in text: ERBB2: H878Y

PubMed Link: 21727090

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• supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1

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Role of ErbB family receptor tyrosine kinases in intrahepatic cholangiocarcinoma.

World Journal Of Gastroenterology

Sirica, Alphonse-E AE

Publication Date: 2008-12-14

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PubMed Link: 19084911

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A novel mutation in the tyrosine kinase domain of ERBB2 in hepatocellular carcinoma.

Bmc Cancer

Bekaii-Saab, Tanios T; Williams, Nita N; Plass, Christoph C; Calero, Miguel Villalona MV; Eng, Charis C

Publication Date: 2006-12-06

Variant appearance in text: ERBB2: 2632C>T; H878Y

PubMed Link: 17150109

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• 1471-2407-6-278.pdf

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