ERBB2 c.2908C>T ;(p.R970W)

Variant ID: 17-37882850-C-T

NM_004448.2(ERBB2):c.2908C>T;(p.R970W)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Molecular landscape of TP53 mutations in breast cancer and their utility for predicting the response to HER-targeted therapy in HER2 amplification-positive and HER2 mutation-positive amplification-negative patients.

Cancer Medicine
Liu, Binliang B; Yi, Zongbi Z; Guan, Yanfang Y; Ouyang, Quchang Q; Li, Chunxiao C; Guan, Xiuwen X; Lv, Dan D; Li, Lixi L; Zhai, Jingtong J; Qian, Haili H; Xu, Binghe B; Ma, Fei F; Zeng, Yixin Y
Publication Date: 2022-07

Variant appearance in text: ERBB2: 2908C>T; R970W
PubMed Link: 35393784
Variant Present in the following documents:
  • CAM4-11-2767-s001.xlsx, sheet 1
View BVdb publication page



Integrated molecular drivers coordinate biological and clinical states in melanoma.

Nature Genetics
Conway, Jake R JR; Dietlein, Felix F; Taylor-Weiner, Amaro A; AlDubayan, Saud S; Vokes, Natalie N; Keenan, Tanya T; Reardon, Brendan B; He, Meng Xiao MX; Margolis, Claire A CA; Weirather, Jason L JL; Haq, Rizwan R; Schilling, Bastian B; Stephen Hodi, F F; Schadendorf, Dirk D; Liu, David D; Van Allen, Eliezer M EM
Publication Date: 2020-12

Variant appearance in text: ERBB2: 2908C>T; R970W
PubMed Link: 33230298
Variant Present in the following documents:
  • NIHMS1637640-supplement-SuppData1.xlsx, sheet 1
View BVdb publication page



Molecular landscape and efficacy of HER2-targeted therapy in patients with HER2-mutated metastatic breast cancer.

Npj Breast Cancer
Yi, Zongbi Z; Rong, Guohua G; Guan, Yanfang Y; Li, Jin J; Chang, Lianpeng L; Li, Hui H; Liu, Binliang B; Wang, Wenna W; Guan, Xiuwen X; Ouyang, Quchang Q; Li, Lixi L; Zhai, Jingtong J; Li, Chunxiao C; Li, Lifeng L; Xia, Xuefeng X; Yang, Ling L; Qian, Haili H; Yi, Xin X; Xu, Binghe B; Ma, Fei F
Publication Date: 2020

Variant appearance in text: ERBB2: 2908C>T; R970W
PubMed Link: 33145402
Variant Present in the following documents:
  • 41523_2020_201_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Integrative analysis of genomic alterations in triple-negative breast cancer in association with homologous recombination deficiency.

Plos Genetics
Kawazu, Masahito M; Kojima, Shinya S; Ueno, Toshihide T; Totoki, Yasushi Y; Nakamura, Hiromi H; Kunita, Akiko A; Qu, Wei W; Yoshimura, Jun J; Soda, Manabu M; Yasuda, Takahiko T; Hama, Natsuko N; Saito-Adachi, Mihoko M; Sato, Kazuhito K; Kohsaka, Shinji S; Sai, Eirin E; Ikemura, Masako M; Yamamoto, Shigeru S; Ogawa, Tomoko T; Fukayama, Masashi M; Tada, Keiichiro K; Seto, Yasuyuki Y; Morishita, Shinichi S; Hazama, Shoichi S; Shibata, Tatsuhiro T; Yamashita, Yoshihiro Y; Mano, Hiroyuki H
Publication Date: 2017-06

Variant appearance in text: ERBB2: R970W
PubMed Link: 28636652
Variant Present in the following documents:
  • pgen.1006853.s012.xlsx, sheet 1
View BVdb publication page



Protein domain-level landscape of cancer-type-specific somatic mutations.

Plos Computational Biology
Yang, Fan F; Petsalaki, Evangelia E; Rolland, Thomas T; Hill, David E DE; Vidal, Marc M; Roth, Frederick P FP
Publication Date: 2015-03

Variant appearance in text: ERBB2: R970W
PubMed Link: 25794154
Variant Present in the following documents:
  • pcbi.1004147.s001.xlsx, sheet 1
View BVdb publication page