PIKfyve activity is required for lysosomal trafficking of tau aggregates and tau seeding.
The Journal Of Biological Chemistry
Soares, Alberto Carpinteiro AC; Ferreira, Andreia A; Mariën, Jonas J; Delay, Charlotte C; Lee, Edward E; Trojanowski, John Q JQ; Moechars, Dieder D; Annaert, Wim W; De Muynck, Louis L
The Mutational Landscape of Metastatic Castration-sensitive Prostate Cancer: The Spectrum Theory Revisited.
European Urology
Deek, Matthew P MP; Van der Eecken, Kim K; Phillips, Ryan R; Parikh, Neil R NR; Isaacsson Velho, Pedro P; Lotan, Tamara L TL; Kishan, Amar U AU; Maurer, Tobias T; , ; Boutros, Paul C PC; Hovens, Christopher C; Abramowtiz, Matthew M; Pollack, Alan A; Desai, Neil N; Stish, Bradley B; Feng, Felix Y FY; Eisenberger, Mario M; Carducci, Michael M; Pienta, Kenneth J KJ; Markowski, Mark M; Paller, Channing J CJ; Antonarakis, Emmanuel S ES; Berlin, Alejandro A; Ost, Piet P; Tran, Phuoc T PT
Development of a personalized therapeutic strategy for ERBB-gene-mutated cancers.
Therapeutic Advances In Medical Oncology
Milewska, Malgorzata M; Cremona, Mattia M; Morgan, Clare C; O'Shea, John J; Carr, Aoife A; Vellanki, Sri H SH; Hopkins, Ann M AM; Toomey, Sinead S; Madden, Stephen F SF; Hennessy, Bryan T BT; Eustace, Alex J AJ
Implementing precision cancer medicine in the public health services of Norway: the diagnostic infrastructure and a cost estimate.
Esmo Open
Ree, Anne Hansen AH; Russnes, Hege G HG; Heinrich, Daniel D; Dueland, Svein S; Boye, Kjetil K; Nygaard, Vigdis V; Silwal-Pandit, Laxmi L; Østrup, Olga O; Hovig, Eivind E; Nygaard, Vegard V; Rødland, Einar A EA; Nakken, Sigve S; Øien, Janne T JT; Johansen, Christin C; Bergheim, Inger R IR; Skarpeteig, Veronica V; Sathermugathevan, Menaka M; Sauer, Torill T; Lund-Iversen, Marius M; Beiske, Klaus K; Nasser, Salah S; Julsrud, Lars L; Reisse, Claudius H CH; Ruud, Espen A EA; Flørenes, Vivi Ann VA; Hagene, Kirsten T KT; Aas, Eline E; Lurås, Hilde H; Johnsen-Soriano, Siv S; Geitvik, Gry A GA; Lingjærde, Ole Christian OC; Børresen-Dale, Anne-Lise AL; Mælandsmo, Gunhild M GM; Flatmark, Kjersti K
ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A.
Nature Communications
Williamson, Chris T CT; Miller, Rowan R; Pemberton, Helen N HN; Jones, Samuel E SE; Campbell, James J; Konde, Asha A; Badham, Nicholas N; Rafiq, Rumana R; Brough, Rachel R; Gulati, Aditi A; Ryan, Colm J CJ; Francis, Jeff J; Vermulen, Peter B PB; Reynolds, Andrew R AR; Reaper, Philip M PM; Pollard, John R JR; Ashworth, Alan A; Lord, Christopher J CJ
Characterization of DDR2 Inhibitors for the Treatment of DDR2 Mutated Nonsmall Cell Lung Cancer.
Acs Chemical Biology
Terai, Hideki H; Tan, Li L; Beauchamp, Ellen M EM; Hatcher, John M JM; Liu, Qingsong Q; Meyerson, Matthew M; Gray, Nathanael S NS; Hammerman, Peter S PS
Type-specific cell line models for type-specific ovarian cancer research.
Plos One
Anglesio, Michael S MS; Wiegand, Kimberly C KC; Melnyk, Nataliya N; Chow, Christine C; Salamanca, Clara C; Prentice, Leah M LM; Senz, Janine J; Yang, Winnie W; Spillman, Monique A MA; Cochrane, Dawn R DR; Shumansky, Karey K; Shah, Sohrab P SP; Kalloger, Steve E SE; Huntsman, David G DG