Publications:

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Early identification of disease progression in ALK-rearranged lung cancer using circulating tumor DNA analysis.

Npj Precision Oncology

Angeles, Arlou Kristina AK; Christopoulos, Petros P; Yuan, Zhao Z; Bauer, Simone S; Janke, Florian F; Ogrodnik, Simon John SJ; Reck, Martin M; Schlesner, Matthias M; Meister, Michael M; Schneider, Marc A MA; Dietz, Steffen S; Stenzinger, Albrecht A; Thomas, Michael M; Sültmann, Holger H

Publication Date: 2021-12-07

Variant appearance in text: ERBB2: 3743A>G; Y1248C

PubMed Link: 34876698

Variant Present in the following documents:

• 41698_2021_239_MOESM1_ESM.pdf

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ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors.

Cell Reports. Medicine

Portelinha, Ana A; Thompson, Scott S; Smith, Roger A RA; Da Silva Ferreira, Mariana M; Asgari, Zahra Z; Knezevic, Andrea A; Seshan, Venkatraman V; de Stanchina, Elisa E; Gupta, Sandeep S; Denis, Louis L; Younes, Anas A; Reddy, Sanjeeva S

Publication Date: 2021-07-20

Variant appearance in text: HER2: Y1248C

PubMed Link: 34337566

Variant Present in the following documents:

• mmc2.pdf

View BVdb publication page

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Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast.

Communications Biology

Nagasawa, Satoi S; Kuze, Yuta Y; Maeda, Ichiro I; Kojima, Yasuyuki Y; Motoyoshi, Ai A; Onishi, Tatsuya T; Iwatani, Tsuguo T; Yokoe, Takamichi T; Koike, Junki J; Chosokabe, Motohiro M; Kubota, Manabu M; Seino, Hibiki H; Suzuki, Ayako A; Seki, Masahide M; Tsuchihara, Katsuya K; Inoue, Eisuke E; Tsugawa, Koichiro K; Ohta, Tomohiko T; Suzuki, Yutaka Y

Publication Date: 2021-04-01

Variant appearance in text: ERBB2: Y1248C

PubMed Link: 33795819

Variant Present in the following documents:

• 42003_2021_1959_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Deep phylogeny of cancer drivers and compensatory mutations.

Communications Biology

Rochman, Nash D ND; Wolf, Yuri I YI; Koonin, Eugene V EV

Publication Date: 2020-10-02

Variant appearance in text: HER2: Y1248C

PubMed Link: 33009502

Variant Present in the following documents:

• 42003_2020_1276_MOESM14_ESM.xlsx, sheet 1

View BVdb publication page

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Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.

Cell Reports

Way, Gregory P GP; Sanchez-Vega, Francisco F; La, Konnor K; Armenia, Joshua J; Chatila, Walid K WK; Luna, Augustin A; Sander, Chris C; Cherniack, Andrew D AD; Mina, Marco M; Ciriello, Giovanni G; Schultz, Nikolaus N; , ; Sanchez, Yolanda Y; Greene, Casey S CS

Publication Date: 2018-04-03

Variant appearance in text: ERBB2: Tyr1248Cys

PubMed Link: 29617658

Variant Present in the following documents:

• NIHMS958974-supplement-6.xlsx, sheet 1

View BVdb publication page

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Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and Are Primed for Neoplastic Progression.

Molecular Cancer Research : Mcr

Drew, David A DA; Mo, Allen A; Grady, James J JJ; Stevens, Richard G RG; Levine, Joel B JB; Brenner, Bruce M BM; Anderson, Joseph C JC; Forouhar, Faripour F; O'Brien, Michael J MJ; Devers, Thomas J TJ; Rosenberg, Daniel W DW

Publication Date: 2018-03

Variant appearance in text: ERBB2: Y1248C

PubMed Link: 29222172

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications

Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ

Publication Date: 2017-08-04

Variant appearance in text: ERBB2: 3743A>G; Y1248C

PubMed Link: 28775315

Variant Present in the following documents:

• 41467_2017_289_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Whole-genome analysis of papillary kidney cancer finds significant noncoding alterations.

Plos Genetics

Li, Shantao S; Shuch, Brian M BM; Gerstein, Mark B MB

Publication Date: 2017-03

Variant appearance in text: HER2: Y1248C

PubMed Link: 28358873

Variant Present in the following documents:

• Main text
• pgen.1006685.pdf

View BVdb publication page

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Determination of somatic oncogenic mutations linked to target-based therapies using MassARRAY technology.

Oncotarget

Ibarrola-Villava, Maider M; Fleitas, Tania T; Llorca-Cardeñosa, Marta J MJ; Mongort, Cristina C; Alonso, Elisa E; Navarro, Samuel S; Burgues, Octavio O; Vivancos, Ana A; Cejalvo, Juan Miguel JM; Perez-Fidalgo, José Alejandro JA; Roselló, Susana S; Ribas, Gloria G; Cervantes, Andrés A

Publication Date: 2016-04-19

Variant appearance in text: ERBB2: Y1248C

PubMed Link: 26968814

Variant Present in the following documents:

• oncotarget-07-22543-s001.pdf

View BVdb publication page

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Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

The Journal Of Molecular Diagnostics : Jmd

MacConaill, Laura E LE; Garcia, Elizabeth E; Shivdasani, Priyanka P; Ducar, Matthew M; Adusumilli, Ravali R; Breneiser, Marc M; Byrne, Mark M; Chung, Lawrence L; Conneely, Jodie J; Crosby, Lauren L; Garraway, Levi A LA; Gong, Xin X; Hahn, William C WC; Hatton, Charlie C; Kantoff, Philip W PW; Kluk, Michael M; Kuo, Frank F; Jia, Yonghui Y; Joshi, Ruchi R; Longtine, Janina J; Manning, Allison A; Palescandolo, Emanuele E; Sharaf, Nematullah N; Sholl, Lynette L; van Hummelen, Paul P; Wade, Jacqueline J; Wollinson, Bruce M BM; Zepf, Dimity D; Rollins, Barrett J BJ; Lindeman, Neal I NI

Publication Date: 2014-11

Variant appearance in text: ERBB2: Y1248C

PubMed Link: 25157968

Variant Present in the following documents:

• Main text

View BVdb publication page

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Panel based MALDI-TOF tumour profiling is a sensitive method for detecting mutations in clinical non small cell lung cancer tumour.

Plos One

Sherwood, James L JL; Müller, Susanne S; Orr, Maria C M MC; Ratcliffe, Marianne J MJ; Walker, Jill J

Publication Date: 2014

Variant appearance in text: ERBB2: Y1248C

PubMed Link: 24956168

Variant Present in the following documents:

• Main text
• pone.0100566.pdf

View BVdb publication page

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Next generation MUT-MAP, a high-sensitivity high-throughput microfluidics chip-based mutation analysis panel.

Plos One

Schleifman, Erica B EB; Tam, Rachel R; Patel, Rajesh R; Tsan, Alison A; Sumiyoshi, Teiko T; Fu, Ling L; Desai, Rupal R; Schoenbrunner, Nancy N; Myers, Thomas W TW; Bauer, Keith K; Smith, Edward E; Raja, Rajiv R

Publication Date: 2014

Variant appearance in text: ERBB2: Y1248C

PubMed Link: 24658394

Variant Present in the following documents:

• pone.0090761.pdf

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Assessment of computational methods for predicting the effects of missense mutations in human cancers.

Bmc Genomics

Gnad, Florian F; Baucom, Albion A; Mukhyala, Kiran K; Manning, Gerard G; Zhang, Zemin Z

Publication Date: 2013

Variant appearance in text: ERBB2: Y1248C

PubMed Link: 23819521

Variant Present in the following documents:

• 1471-2164-14-S3-S7-S1.xlsx, sheet 1

View BVdb publication page

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HGF-MET cascade, a key target for inhibiting cancer metastasis: the impact of NK4 discovery on cancer biology and therapeutics.

International Journal Of Molecular Sciences

Mizuno, Shinya S; Nakamura, Toshikazu T

Publication Date: 2013-01-07

Variant appearance in text: HER2: Y1248C

PubMed Link: 23296269

Variant Present in the following documents:

• ijms-14-00888.pdf

View BVdb publication page

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