Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.
Cancer Research Communications
White, Jason A JA; Kaninjing, Ernest T ET; Adeniji, Kayode A KA; Jibrin, Paul P; Obafunwa, John O JO; Ogo, Chidiebere N CN; Mohammed, Faruk F; Popoola, Ademola A; Fatiregun, Omolara A OA; Oluwole, Olabode P OP; Karanam, Balasubramanyam B; Elhussin, Isra I; Ambs, Stefan S; Tang, Wei W; Davis, Melissa M; Polak, Paz P; Campbell, Moray J MJ; Brignole, Kathryn R KR; Rotimi, Solomon O SO; Dean-Colomb, Windy W; Odedina, Folake T FT; Martin, Damali N DN; Yates, Clayton C
BARD1 mystery: tumor suppressors are cancer susceptibility genes.
Bmc Cancer
Hawsawi, Yousef M YM; Shams, Anwar A; Theyab, Abdulrahman A; Abdali, Wed A WA; Hussien, Nahed A NA; Alatwi, Hanan E HE; Alzahrani, Othman R OR; Oyouni, Atif Abdulwahab A AAA; Babalghith, Ahmad O AO; Alreshidi, Mousa M
Detection of Marker-Free Precision Genome Editing and Genetic Variation through the Capture of Genomic Signatures.
Cell Reports
Billon, Pierre P; Nambiar, Tarun S TS; Hayward, Samuel B SB; Zafra, Maria P MP; Schatoff, Emma M EM; Oshima, Koichi K; Dunbar, Andrew A; Breinig, Marco M; Park, Young C YC; Ryu, Han S HS; Tschaharganeh, Darjus F DF; Levine, Ross L RL; Baer, Richard R; Ferrando, Adolfo A; Dow, Lukas E LE; Ciccia, Alberto A
Comprehensive annotation of BRCA1 and BRCA2 missense variants by functionally validated sequence-based computational prediction models.
Genetics In Medicine : Official Journal Of The American College Of Medical Genetics
Hart, Steven N SN; Hoskin, Tanya T; Shimelis, Hermela H; Moore, Raymond M RM; Feng, Bingjian B; Thomas, Abigail A; Lindor, Noralane M NM; Polley, Eric C EC; Goldgar, David E DE; Iversen, Edwin E; Monteiro, Alvaro N A ANA; Suman, Vera J VJ; Couch, Fergus J FJ
Gene-Specific Genetic Complementation between Brca1 and Cobra1 During Mouse Mammary Gland Development.
Scientific Reports
Chiang, Huai-Chin HC; Zhang, Xiaowen X; Zhao, Xiayan X; Zhang, Chi C; Chen, Jerry J; Garza, Paula P; Smith, Sabrina S; Ludwig, Thomas T; Baer, Richard J RJ; Li, Rong R; Hu, Yanfen Y
BRCA1 through Its E3 Ligase Activity Regulates the Transcription Factor Oct1 and Carbohydrate Metabolism.
Molecular Cancer Research : Mcr
Vázquez-Arreguín, Karina K; Maddox, Jessica J; Kang, Jinsuk J; Park, Dongju D; Cano, Reuben R RR; Factor, Rachel E RE; Ludwig, Thomas T; Tantin, Dean D
Integrating Gene Correction in the Reprogramming and Transdifferentiation Processes: A One-Step Strategy to Overcome Stem Cell-Based Gene Therapy Limitations.
Reduced BRCA1 transcript levels in freshly isolated blood leukocytes from BRCA1 mutation carriers is mutation specific.
Breast Cancer Research : Bcr
Chehade, Rania R; Pettapiece-Phillips, Rachael R; Salmena, Leonardo L; Kotlyar, Max M; Jurisica, Igor I; Narod, Steven A SA; Akbari, Mohammad R MR; Kotsopoulos, Joanne J
Biallelic deleterious BRCA1 mutations in a woman with early-onset ovarian cancer.
Cancer Discovery
Domchek, Susan M SM; Tang, Jiangbo J; Stopfer, Jill J; Lilli, Dana R DR; Hamel, Nancy N; Tischkowitz, Marc M; Monteiro, Alvaro N A AN; Messick, Troy E TE; Powers, Jacquelyn J; Yonker, Alexandria A; Couch, Fergus J FJ; Goldgar, David E DE; Davidson, H Rosemarie HR; Nathanson, Katherine L KL; Foulkes, William D WD; Greenberg, Roger A RA
BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity.
Science (New York, N.Y.)
Shakya, Reena R; Reid, Latarsha J LJ; Reczek, Colleen R CR; Cole, Francesca F; Egli, Dieter D; Lin, Chyuan-Sheng CS; deRooij, Dirk G DG; Hirsch, Steffen S; Ravi, Kandasamy K; Hicks, James B JB; Szabolcs, Matthias M; Jasin, Maria M; Baer, Richard R; Ludwig, Thomas T