Benchmarking of SpCas9 variants enables deeper base editor screens of BRCA1 and BCL2.
Nature Communications
Sangree, Annabel K AK; Griffith, Audrey L AL; Szegletes, Zsofia M ZM; Roy, Priyanka P; DeWeirdt, Peter C PC; Hegde, Mudra M; McGee, Abby V AV; Hanna, Ruth E RE; Doench, John G JG
Comprehensive annotation of BRCA1 and BRCA2 missense variants by functionally validated sequence-based computational prediction models.
Genetics In Medicine : Official Journal Of The American College Of Medical Genetics
Hart, Steven N SN; Hoskin, Tanya T; Shimelis, Hermela H; Moore, Raymond M RM; Feng, Bingjian B; Thomas, Abigail A; Lindor, Noralane M NM; Polley, Eric C EC; Goldgar, David E DE; Iversen, Edwin E; Monteiro, Alvaro N A ANA; Suman, Vera J VJ; Couch, Fergus J FJ