TP53 c.1099_1100delinsGC ;(p.S367A)

Variant ID: 17-7573927-CT-GC

NM_000546.5(TP53):c.1099_1100delinsGC;(p.S367A)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Regulation of p53 by the 14-3-3 protein interaction network: new opportunities for drug discovery in cancer.

Cell Death Discovery
Falcicchio, Marta M; Ward, Jake A JA; Macip, Salvador S; Doveston, Richard G RG
Publication Date: 2020-11-16

Variant appearance in text: p53: S367A
PubMed Link: 33298896
Variant Present in the following documents:
  • 41420_2020_Article_362.pdf
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Oncoprotein YAP regulates the spindle checkpoint activation in a mitotic phosphorylation-dependent manner through up-regulation of BubR1.

The Journal Of Biological Chemistry
Yang, Shuping S; Zhang, Lin L; Chen, Xingcheng X; Chen, Yuanhong Y; Dong, Jixin J
Publication Date: 2015-03-06

Variant appearance in text: p53: S367A
PubMed Link: 25605730
Variant Present in the following documents:
  • Main text
View BVdb publication page



Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma.

Science Signaling
Zhang, Weiying W; Nandakumar, Nivedita N; Shi, Yuhao Y; Manzano, Mark M; Smith, Alias A; Graham, Garrett G; Gupta, Swati S; Vietsch, Eveline E EE; Laughlin, Sean Z SZ; Wadhwa, Mandheer M; Chetram, Mahandranauth M; Joshi, Mrinmayi M; Wang, Fen F; Kallakury, Bhaskar B; Toretsky, Jeffrey J; Wellstein, Anton A; Yi, Chunling C
Publication Date: 2014-05-06

Variant appearance in text: p53: S367A
PubMed Link: 24803537
Variant Present in the following documents:
  • Main text
View BVdb publication page



Protein phosphatase 1 inhibits p53 signaling by dephosphorylating and stabilizing Mdmx.

Cellular Signalling
Lu, Zengxin Z; Wan, Guohui G; Guo, Huarong H; Zhang, Xinna X; Lu, Xiongbin X
Publication Date: 2013-04

Variant appearance in text: p53: S367A
PubMed Link: 23277204
Variant Present in the following documents:
  • Main text
View BVdb publication page



Differential roles of ATM- and Chk2-mediated phosphorylations of Hdmx in response to DNA damage.

Molecular And Cellular Biology
Pereg, Yaron Y; Lam, Suzanne S; Teunisse, Amina A; Biton, Sharon S; Meulmeester, Erik E; Mittelman, Leonid L; Buscemi, Giacomo G; Okamoto, Koji K; Taya, Yoichi Y; Shiloh, Yosef Y; Jochemsen, Aart G AG
Publication Date: 2006-09

Variant appearance in text: p53: S367A
PubMed Link: 16943424
Variant Present in the following documents:
  • Main text
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DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.

Molecular And Cellular Biology
Okamoto, Koji K; Kashima, Kenji K; Pereg, Yaron Y; Ishida, Michiko M; Yamazaki, Satomi S; Nota, Ayumi A; Teunisse, Amina A; Migliorini, Domenico D; Kitabayashi, Issay I; Marine, Jean-Christophe JC; Prives, Carol C; Shiloh, Yosef Y; Jochemsen, Aart G AG; Taya, Yoichi Y
Publication Date: 2005-11

Variant appearance in text: p53: S367A
PubMed Link: 16227609
Variant Present in the following documents:
  • Main text
View BVdb publication page