Publications:

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Genetic mutations in HER2-positive breast cancer: possible association with response to trastuzumab therapy.

Human Genomics

Zakaria, Nermine H NH; Hashad, Doaa D; Saied, Marwa H MH; Hegazy, Neamat N; Elkayal, Alyaa A; Tayae, Eman E

Publication Date: 2023-05-18

Variant appearance in text: TP53: Leu344Pro; rs121912662

PubMed Link: 37202799

Variant Present in the following documents:

• Main text
• 40246_2023_Article_493.pdf

View BVdb publication page

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Rational design of phase separating peptides based on phase separating protein sequence of p53.

Scientific Reports

Kamagata, Kiyoto K; Hando, Atsumi A; Ariefai, Maulana M; Iwaki, Nanako N; Kanbayashi, Saori S; Koike, Ryotaro R; Ikeda, Keisuke K

Publication Date: 2023-04-06

Variant appearance in text: p53: L344P

PubMed Link: 37024567

Variant Present in the following documents:

• Main text
• 41598_2023_Article_32632.pdf

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: TP53: 1031T>C; Leu344Pro

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Application of Genomic Sequencing to Refine Patient Stratification for Adjuvant Therapy in Renal Cell Carcinoma.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Vasudev, Naveen S NS; Scelo, Ghislaine G; Glennon, Kate I KI; Wilson, Michelle M; Letourneau, Louis L; Eveleigh, Robert R; Nourbehesht, Nazanin N; Arseneault, Madeleine M; Paccard, Antoine A; Egevad, Lars L; Viksna, Juris J; Celms, Edgars E; Jackson, Sharon M SM; Abedi-Ardekani, Behnoush B; Warren, Anne Y AY; Selby, Peter J PJ; Trainor, Sebastian S; Kimuli, Michael M; Cartledge, Jon J; Soomro, Naeem N; Adeyoju, Adebanji A; Patel, Poulam M PM; Wozniak, Magdalena B MB; Holcatova, Ivana I; Brisuda, Antonin A; Janout, Vladimir V; Chanudet, Estelle E; Zaridze, David D; Moukeria, Anush A; Shangina, Oxana O; Foretova, Lenka L; Navratilova, Marie M; Mates, Dana D; Jinga, Viorel V; Bogdanovic, Ljiljana L; Kovacevic, Bozidar B; Cambon-Thomsen, Anne A; Bourque, Guillaume G; Brazma, Alvis A; Tost, Jörg J; Brennan, Paul P; Lathrop, Mark M; Riazalhosseini, Yasser Y; Banks, Rosamonde E RE

Publication Date: 2023-02-23

Variant appearance in text: TP53: 1031T>C; Leu344Pro; rs121912662

PubMed Link: 36815791

Variant Present in the following documents:

• ccr-22-1936_supplementary_table_s2_suppts2.xlsx, sheet 1

View BVdb publication page

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Clinical sequencing identifies potential actionable alterations in a high rate of urachal and primary bladder adenocarcinomas.

Cancer Medicine

Varadi, Melinda M; Nagy, Nikolett N; Reis, Henning H; Hadaschik, Boris B; Niedworok, Christian C; Modos, Orsolya O; Szendroi, Attila A; Ablat, Jason J; Black, Peter C PC; Keresztes, David D; Csizmarik, Anita A; Olah, Csilla C; Gaisa, Nadine T NT; Kiss, Andras A; Timar, Jozsef J; Toth, Erika E; Csernak, Erzsebet E; Gerstner, Arpad A; Mittal, Vinay V; Karkampouna, Sofia S; Kruithof de Julio, Marianna M; Gyorffy, Balazs B; Bedics, Gabor G; Rink, Michael M; Fisch, Margit M; Nyirady, Peter P; Szarvas, Tibor T

Publication Date: 2023-01-20

Variant appearance in text: TP53: Leu344Pro

PubMed Link: 36670542

Variant Present in the following documents:

• CAM4-12-9041-s001.xlsx, sheet 2
• CAM4-12-9041-s001.xlsx, sheet 1

View BVdb publication page

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Influence of chain length and branching on poly(ADP-ribose)-protein interactions.

Nucleic Acids Research

Löffler, Tobias T; Krüger, Annika A; Zirak, Peyman P; Winterhalder, Martin J MJ; Müller, Anna-Lena AL; Fischbach, Arthur A; Mangerich, Aswin A; Zumbusch, Andreas A

Publication Date: 2023-01-10

Variant appearance in text: p53: L344P

PubMed Link: 36625274

Variant Present in the following documents:

• Main text
• gkac1235.pdf

View BVdb publication page

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ESR1 gene amplification and MAP3K mutations are selected during adjuvant endocrine therapies in relapsing Hormone Receptor-positive, HER2-negative breast cancer (HR+ HER2- BC).

Plos Genetics

Ferrando, Lorenzo L; Vingiani, Andrea A; Garuti, Anna A; Vernieri, Claudio C; Belfiore, Antonino A; Agnelli, Luca L; Dagrada, Gianpaolo G; Ivanoiu, Diana D; Bonizzi, Giuseppina G; Munzone, Elisabetta E; Lippolis, Luana L; Dameri, Martina M; Ravera, Francesco F; Colleoni, Marco M; Viale, Giuseppe G; Magnani, Luca L; Ballestrero, Alberto A; Zoppoli, Gabriele G; Pruneri, Giancarlo G

Publication Date: 2023-01-03

Variant appearance in text: rs121912662

PubMed Link: 36595552

Variant Present in the following documents:

• pgen.1010563.s004.xlsx, sheet 1

View BVdb publication page

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: rs121912662

PubMed Link: 36561320

Variant Present in the following documents:

• Table2.xlsx, sheet 7

View BVdb publication page

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CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience

Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X

Publication Date: 2022-09-16

Variant appearance in text: p53: 1031T>C

PubMed Link: 36117989

Variant Present in the following documents:

• mmc4.xlsx, sheet 1

View BVdb publication page

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Landscape of somatic alterations in large-scale solid tumors from an Asian population.

Nature Communications

Wu, Liqun L; Yao, Herui H; Chen, Hui H; Wang, Aodi A; Guo, Kun K; Gou, Wenli W; Yu, Yanfei Y; Li, Xiang X; Yao, Ming M; Yuan, Shaohua S; Pang, Fei F; Hu, Jinwei J; Chen, Lijuan L; Liu, Wenjin W; Yao, Jicheng J; Zhang, Shuirong S; Dong, Xiaowei X; Wang, Weifeng W; Hu, Jing J; Ling, Qi Q; Ding, Songming S; Wei, Yan Y; Li, Qiang Q; Cao, Weichun W; Wang, Shuang S; Di, Yang Y; Feng, Feiling F; Zhao, Gang G; Zhang, Jian J; Huang, Ling L; Xu, Jia J; Yan, Wangjun W; Tong, Zhongsheng Z; Jiang, Da D; Ji, Tao T; Li, Qiao Q; Xu, Ling L; He, Huiying H; Shang, Liang L; Liu, Jin J; Wang, Kefeng K; Wu, Duoguang D; Shen, Jingnan J; Liu, Ye Y; Zhang, Ting T; Liang, Chaojie C; Wang, Yusheng Y; Shang, Yanhong Y; Guo, Jianji J; Liang, Guanbiao G; Xu, Shifeng S; Liu, Junfeng J; Wang, Kai K; Wang, Minghui M

Publication Date: 2022-07-23

Variant appearance in text: TP53: L344P

PubMed Link: 35871175

Variant Present in the following documents:

• 41467_2022_31780_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications

Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX

Publication Date: 2022-06-15

Variant appearance in text: TP53: L344P

PubMed Link: 35705558

Variant Present in the following documents:

• 41467_2022_30496_MOESM2_ESM.xls, sheet 1

View BVdb publication page

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Synthetic lethality between TP53 and ENDOD1.

Nature Communications

Tang, Zizhi Z; Zeng, Ming M; Wang, Xiaojun X; Guo, Chang C; Yue, Peng P; Zhang, Xiaohu X; Lou, Huiqiang H; Chen, Jun J; Mu, Dezhi D; Kong, Daochun D; Carr, Antony M AM; Liu, Cong C

Publication Date: 2022-05-23

Variant appearance in text: TP53: L344P

PubMed Link: 35606358

Variant Present in the following documents:

• Main text
• 41467_2022_30311_MOESM1_ESM.pdf
• 41467_2022_Article_30311.pdf

View BVdb publication page

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Mutual exclusivity of ESR1 and TP53 mutations in endocrine resistant metastatic breast cancer.

Npj Breast Cancer

Li, Zheqi Z; Spoelstra, Nicole S NS; Sikora, Matthew J MJ; Sams, Sharon B SB; Elias, Anthony A; Richer, Jennifer K JK; Lee, Adrian V AV; Oesterreich, Steffi S

Publication Date: 2022-05-10

Variant appearance in text: TP53: L344P

PubMed Link: 35538119

Variant Present in the following documents:

• 41523_2022_426_MOESM1_ESM.pdf

View BVdb publication page

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Integrative proteogenomic characterization of hepatocellular carcinoma across etiologies and stages.

Nature Communications

Ng, Charlotte K Y CKY; Dazert, Eva E; Boldanova, Tuyana T; Coto-Llerena, Mairene M; Nuciforo, Sandro S; Ercan, Caner C; Suslov, Aleksei A; Meier, Marie-Anne MA; Bock, Thomas T; Schmidt, Alexander A; Ketterer, Sylvia S; Wang, Xueya X; Wieland, Stefan S; Matter, Matthias S MS; Colombi, Marco M; Piscuoglio, Salvatore S; Terracciano, Luigi M LM; Hall, Michael N MN; Heim, Markus H MH

Publication Date: 2022-05-04

Variant appearance in text: TP53: 1031T>C; Leu344Pro; rs121912662

PubMed Link: 35508466

Variant Present in the following documents:

• 41467_2022_29960_MOESM12_ESM.xlsx, sheet 1

View BVdb publication page

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Structure-dependent recruitment and diffusion of guest proteins in liquid droplets of FUS.

Scientific Reports

Kamagata, Kiyoto K; Iwaki, Nanako N; Kanbayashi, Saori S; Banerjee, Trishit T; Chiba, Rika R; Gaudon, Virginie V; Castaing, Bertrand B; Sakomoto, Seiji S

Publication Date: 2022-05-02

Variant appearance in text: p53: L344P

PubMed Link: 35501371

Variant Present in the following documents:

• Main text
• 41598_2022_Article_11177.pdf

View BVdb publication page

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Recurrent transcriptional responses in AML and MDS patients treated with decitabine.

Experimental Hematology

Upadhyay, Pawan P; Beales, Jeremy J; Shah, Nakul M NM; Gruszczynska, Agata A; Miller, Christopher A CA; Petti, Allegra A AA; Ramakrishnan, Sai Mukund SM; Link, Daniel C DC; Ley, Timothy J TJ; Welch, John S JS

Publication Date: 2022-07

Variant appearance in text: TP53: L344P

PubMed Link: 35429619

Variant Present in the following documents:

• NIHMS1838743-supplement-MMC1.pdf

View BVdb publication page

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Soft Tissue Sarcoma Study: Association of Genetic Alterations in the Apoptosis Pathways with Chemoresistance to Doxorubicin.

Cancers

Kirilin, Evgeny M EM; Fetisov, Timur I TI; Moiseeva, Natalia I NI; Lesovaya, Ekaterina A EA; Laletina, Lidia A LA; Makhmudova, Leyla F LF; Manikaylo, Angelika E AE; Fomina, Liliya Y LY; Burov, Denis A DA; Bokhyan, Beniamin Yu BY; Zinovieva, Victoria Y VY; Vilkova, Alice S AS; Mekheda, Larisa V LV; Kozlov, Nikolay A NA; Scherbakov, Alexander M AM; Belitsky, Gennady A GA; Švedas, Vytas V; Kirsanov, Kirill I KI; Yakubovskaya, Marianna G MG

Publication Date: 2022-04-01

Variant appearance in text: TP53: Leu344Pro

PubMed Link: 35406568

Variant Present in the following documents:

• Main text
• cancers-14-01796.pdf

View BVdb publication page

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Different Oligomeric States of the Tumor Suppressor p53 Show Identical Binding Behavior towards the S100β Homodimer.

Chembiochem : A European Journal Of Chemical Biology

Wei, Alan An Jung AAJ; Iacobucci, Claudio C; Schultze, Wiebke W; Ihling, Christian H CH; Arlt, Christian C; Sinz, Andrea A

Publication Date: 2022-06-03

Variant appearance in text: p53: L344P

PubMed Link: 35333001

Variant Present in the following documents:

• CBIC-23-0.pdf
• CBIC-23-0-s001.pdf

View BVdb publication page

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Deep sequencing in CD34+ cells from peripheral blood enables sensitive detection of measurable residual disease in AML.

Blood Advances

Stasik, Sebastian S; Burkhard-Meier, Clara C; Kramer, Michael M; Middeke, Jan M JM; Oelschlaegel, Uta U; Sockel, Katja K; Ehninger, Gerhard G; Serve, Hubert H; Müller-Tidow, Carsten C; Baldus, Claudia D CD; Röllig, Christoph C; Bornhäuser, Martin M; Platzbecker, Uwe U; Thiede, Christian C

Publication Date: 2022-06-14

Variant appearance in text: TP53: 1031T>C

PubMed Link: 35320339

Variant Present in the following documents:

• advancesADV2021006233-suppl1.pdf

View BVdb publication page

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Rapid recruitment of p53 to DNA damage sites directs DNA repair choice and integrity.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Wang, Yu-Hsiu YH; Ho, Teresa L F TLF; Hariharan, Anushya A; Goh, Hui Chin HC; Wong, Yao Liang YL; Verkaik, Nicole S NS; Lee, May Yin MY; Tam, Wai Leong WL; van Gent, Dik C DC; Venkitaraman, Ashok R AR; Sheetz, Michael P MP; Lane, David P DP

Publication Date: 2022-03-08

Variant appearance in text: p53: L344P

PubMed Link: 35235448

Variant Present in the following documents:

• pnas.202113233.pdf

View BVdb publication page

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Oligomerization of Mutant p53 R273H is not Required for Gain-of-Function Chromatin Associated Activities.

Frontiers In Cell And Developmental Biology

Annor, George K GK; Elshabassy, Nour N; Lundine, Devon D; Conde, Don-Gerard DG; Xiao, Gu G; Ellison, Viola V; Bargonetti, Jill J

Publication Date: 2021

Variant appearance in text: p53: L344P

PubMed Link: 34881245

Variant Present in the following documents:

• Main text
• fcell-09-772315.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: TP53: L344P

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Molecular principles of recruitment and dynamics of guest proteins in liquid droplets.

Scientific Reports

Kamagata, Kiyoto K; Iwaki, Nanako N; Hazra, Milan Kumar MK; Kanbayashi, Saori S; Banerjee, Trishit T; Chiba, Rika R; Sakomoto, Seiji S; Gaudon, Virginie V; Castaing, Bertrand B; Takahashi, Hiroto H; Kimura, Michiko M; Oikawa, Hiroyuki H; Takahashi, Satoshi S; Levy, Yaakov Y

Publication Date: 2021-09-29

Variant appearance in text: p53: L344P

PubMed Link: 34588591

Variant Present in the following documents:

• Main text
• 41598_2021_Article_98955.pdf

View BVdb publication page

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Multimodal liquid biopsy for early monitoring and outcome prediction of chemotherapy in metastatic breast cancer.

Npj Breast Cancer

Bortolini Silveira, Amanda A; Bidard, François-Clément FC; Tanguy, Marie-Laure ML; Girard, Elodie E; Trédan, Olivier O; Dubot, Coraline C; Jacot, William W; Goncalves, Anthony A; Debled, Marc M; Levy, Christelle C; Ferrero, Jean-Marc JM; Jouannaud, Christelle C; Rios, Maria M; Mouret-Reynier, Marie-Ange MA; Dalenc, Florence F; Hego, Caroline C; Rampanou, Aurore A; Albaud, Benoit B; Baulande, Sylvain S; Berger, Frédérique F; Lemonnier, Jérôme J; Renault, Shufang S; Desmoulins, Isabelle I; Proudhon, Charlotte C; Pierga, Jean-Yves JY

Publication Date: 2021-09-09

Variant appearance in text: TP53: 1031T>C; L344P

PubMed Link: 34504096

Variant Present in the following documents:

• 41523_2021_319_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Protein detection in blood with single-molecule imaging.

Science Advances

Mao, Chih-Ping CP; Wang, Shih-Chin SC; Su, Yu-Pin YP; Tseng, Ssu-Hsueh SH; He, Liangmei L; Wu, Annie A AA; Roden, Richard B S RBS; Xiao, Jie J; Hung, Chien-Fu CF

Publication Date: 2021-08

Variant appearance in text: p53: L344P

PubMed Link: 34380620

Variant Present in the following documents:

• Main text

View BVdb publication page

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Protein detection in blood with single-molecule imaging.

Science Advances

Mao, Chih-Ping CP; Wang, Shih-Chin SC; Su, Yu-Pin YP; Tseng, Ssu-Hsueh SH; He, Liangmei L; Wu, Annie A AA; Roden, Richard B S RBS; Xiao, Jie J; Hung, Chien-Fu CF

Publication Date: 2021-08

Variant appearance in text: p53: L344P

PubMed Link: 34380620

Variant Present in the following documents:

• Main text

View BVdb publication page

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A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.

Scientific Reports

Magraner-Pardo, Lorena L; Laskowski, Roman A RA; Pons, Tirso T; Thornton, Janet M JM

Publication Date: 2021-07-12

Variant appearance in text: TP53: 1031T>C; L344P

PubMed Link: 34253785

Variant Present in the following documents:

• 41598_2021_93715_MOESM3_ESM.xlsx, sheet 5
• 41598_2021_93715_MOESM2_ESM.xlsx, sheet 9
• 41598_2021_93715_MOESM3_ESM.xlsx, sheet 2
• 41598_2021_93715_MOESM2_ESM.xlsx, sheet 7
• 41598_2021_93715_MOESM2_ESM.xlsx, sheet 10
• 41598_2021_93715_MOESM3_ESM.xlsx, sheet 6

View BVdb publication page

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Germline variants in hereditary breast cancer genes are associated with early age at diagnosis and family history in Guatemalan breast cancer.

Breast Cancer Research And Treatment

Ren, Megan M; Orozco, Anali A; Shao, Kang K; Albanez, Anaseidy A; Ortiz, Jeremy J; Cao, Boyang B; Wang, Lusheng L; Barreda, Lilian L; Alvarez, Christian S CS; Garland, Lisa L; Wu, Dongjing D; Chung, Charles C CC; Wang, Jiahui J; Frone, Megan M; Ralon, Sergio S; Argueta, Victor V; Orozco, Roberto R; Gharzouzi, Eduardo E; Dean, Michael M

Publication Date: 2021-09

Variant appearance in text: TP53: Leu344Pro; rs121912662

PubMed Link: 34196900

Variant Present in the following documents:

• 10549_2021_6305_MOESM1_ESM.xlsx, sheet 3

View BVdb publication page

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: TP53: 1031T>C; L344P

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

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Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome.

Nature Communications

Kennedy, Alyssa L AL; Myers, Kasiani C KC; Bowman, James J; Gibson, Christopher J CJ; Camarda, Nicholas D ND; Furutani, Elissa E; Muscato, Gwen M GM; Klein, Robert H RH; Ballotti, Kaitlyn K; Liu, Shanshan S; Harris, Chad E CE; Galvin, Ashley A; Malsch, Maggie M; Dale, David D; Gansner, John M JM; Nakano, Taizo A TA; Bertuch, Alison A; Vlachos, Adrianna A; Lipton, Jeffrey M JM; Castillo, Paul P; Connelly, James J; Churpek, Jane J; Edwards, John R JR; Hijiya, Nobuko N; Ho, Richard H RH; Hofmann, Inga I; Huang, James N JN; Keel, Siobán S; Lamble, Adam A; Lau, Bonnie W BW; Norkin, Maxim M; Stieglitz, Elliot E; Stock, Wendy W; Walkovich, Kelly K; Boettcher, Steffen S; Brendel, Christian C; Fleming, Mark D MD; Davies, Stella M SM; Weller, Edie A EA; Bahl, Christopher C; Carter, Scott L SL; Shimamura, Akiko A; Lindsley, R Coleman RC

Publication Date: 2021-02-26

Variant appearance in text: TP53: L344P

PubMed Link: 33637765

Variant Present in the following documents:

• 41467_2021_Article_21588.pdf
• 41467_2021_21588_MOESM1_ESM.pdf

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: TP53: 1031T>C; L344P

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Predictive Biomarkers for Immune Checkpoint Inhibitors in Metastatic Breast Cancer.

Cancer Medicine

Sivapiragasam, Abirami A; Ashok Kumar, Prashanth P; Sokol, Ethan S ES; Albacker, Lee A LA; Killian, Jonathan K JK; Ramkissoon, Shakti H SH; Huang, Richard S P RSP; Severson, Eric A EA; Brown, Charlotte A CA; Danziger, Natalie N; McGregor, Kimberly K; Ross, Jeffrey S JS

Publication Date: 2021-01

Variant appearance in text: TP53: L344P

PubMed Link: 33314633

Variant Present in the following documents:

• CAM4-10-53-s003.xlsx, sheet 1

View BVdb publication page

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STAT3 and TP53 mutations associate with poor prognosis in anaplastic large cell lymphoma.

Leukemia

Lobello, Cosimo C; Tichy, Boris B; Bystry, Vojtech V; Radova, Lenka L; Filip, Daniel D; Mraz, Marek M; Montes-Mojarro, Ivonne-Aidee IA; Prokoph, Nina N; Larose, Hugo H; Liang, Huan-Chang HC; Sharma, Geeta G GG; Mologni, Luca L; Belada, David D; Kamaradova, Katerina K; Fend, Falko F; Gambacorti-Passerini, Carlo C; Merkel, Olaf O; Turner, Suzanne D SD; Janikova, Andrea A; Pospisilova, Sarka S

Publication Date: 2021-05

Variant appearance in text: TP53: L344P

PubMed Link: 33247178

Variant Present in the following documents:

• Main text
• 41375_2020_1093_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Short tandem repeat profiling for the authentication of cancer stem-like cells.

International Journal Of Cancer

Visconti, Paola P; Parodi, Federica F; Parodi, Barbara B; Casarino, Lucia L; Romano, Paolo P; Buccarelli, Mariachiara M; Pallini, Roberto R; D'Alessandris, Quintino Giorgio QG; Montori, Andrea A; Pilozzi, Emanuela E; Ricci-Vitiani, Lucia L

Publication Date: 2021-03-15

Variant appearance in text: TP53: 1031T>C; Leu344Pro

PubMed Link: 33128777

Variant Present in the following documents:

• IJC-148-1489-s001.pdf

View BVdb publication page

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p53 tetramerization: at the center of the dominant-negative effect of mutant p53.

Genes & Development

Gencel-Augusto, Jovanka J; Lozano, Guillermina G

Publication Date: 2020-09-01

Variant appearance in text: p53: L344P

PubMed Link: 32873579

Variant Present in the following documents:

• Main text

View BVdb publication page

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Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate.

Nature Communications

Pandey, Akhilesh A; Stawiski, Eric W EW; Durinck, Steffen S; Gowda, Harsha H; Goldstein, Leonard D LD; Barbhuiya, Mustafa A MA; Schröder, Markus S MS; Sreenivasamurthy, Sreelakshmi K SK; Kim, Sun-Whe SW; Phalke, Sameer S; Suryamohan, Kushal K; Lee, Kayla K; Chakraborty, Papia P; Kode, Vasumathi V; Shi, Xiaoshan X; Chatterjee, Aditi A; Datta, Keshava K; Khan, Aafaque A AA; Subbannayya, Tejaswini T; Wang, Jing J; Chaudhuri, Subhra S; Gupta, Sanjiv S; Shrivastav, Braj Raj BR; Jaiswal, Bijay S BS; Poojary, Satish S SS; Bhunia, Shushruta S; Garcia, Patricia P; Bizama, Carolina C; Rosa, Lorena L; Kwon, Wooil W; Kim, Hongbeom H; Han, Youngmin Y; Yadav, Thakur Deen TD; Ramprasad, Vedam L VL; Chaudhuri, Amitabha A; Modrusan, Zora Z; Roa, Juan Carlos JC; Tiwari, Pramod Kumar PK; Jang, Jin-Young JY; Seshagiri, Somasekar S

Publication Date: 2020-08-24

Variant appearance in text: TP53: 1031T>C; L344P

PubMed Link: 32839463

Variant Present in the following documents:

• 41467_2020_17880_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Single C-to-T substitution using engineered APOBEC3G-nCas9 base editors with minimum genome- and transcriptome-wide off-target effects.

Science Advances

Lee, Sangsin S; Ding, Ning N; Sun, Yidi Y; Yuan, Tanglong T; Li, Jing J; Yuan, Qichen Q; Liu, Lizhong L; Yang, Jie J; Wang, Qian Q; Kolomeisky, Anatoly B AB; Hilton, Isaac B IB; Zuo, Erwei E; Gao, Xue X

Publication Date: 2020-07

Variant appearance in text: TP53: 1031T>C; Leu344Pro

PubMed Link: 32832622

Variant Present in the following documents:

• aba1773_Data_file_S1.xlsx, sheet 2

View BVdb publication page

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Molecular analysis of circulating tumor DNA from breast cancer patients before and after surgery and following adjuvant chemotherapy.

Molecular And Clinical Oncology

Zelinova, Katarina K; Jagelkova, Marianna M; Laucekova, Zuzana Z; Bobrovska, Martina M; Dankova, Zuzana Z; Grendar, Marian M; Dokus, Karol K

Publication Date: 2020-10

Variant appearance in text: TP53: 1031T>C

PubMed Link: 32765873

Variant Present in the following documents:

• Main text
• mco-13-04-02096.pdf
• Supplementary_Data.pdf

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Defining relative mutational difficulty to understand cancer formation.

Cell Discovery

Shan, Lin L; Yu, Jiao J; He, Zhengjin Z; Chen, Shishuang S; Liu, Mingxian M; Ding, Hongyu H; Xu, Liang L; Zhao, Jie J; Yang, Ailing A; Jiang, Hai H

Publication Date: 2020

Variant appearance in text: p53: L344P

PubMed Link: 32704382

Variant Present in the following documents:

• 41421_2020_177_MOESM6_ESM.xlsx, sheet 1
• 41421_2020_177_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns.

Blood Cancer Journal

Schinke, Carolina C; Boyle, Eileen M EM; Ashby, Cody C; Wang, Yan Y; Lyzogubov, Valeriy V; Wardell, Christopher C; Qu, Pingping P; Hoering, Antje A; Deshpande, Shayu S; Ryan, Katie K; Thanendrarajan, Sharmilan S; Mohan, Meera M; Yarlagadda, Naveen N; Khan, Maliha M; Choudhury, Samrat Roy SR; Zangari, Maurizio M; van Rhee, Frits F; Davies, Faith F; Barlogie, Bart B; Morgan, Gareth G; Walker, Brian A BA

Publication Date: 2020-06-19

Variant appearance in text: TP53: L344P

PubMed Link: 32555163

Variant Present in the following documents:

• 41408_2020_336_MOESM1_ESM.pdf

View BVdb publication page

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Classification of gastric cancer by EBV status combined with molecular profiling predicts patient prognosis.

Clinical And Translational Medicine

He, Cai-Yun CY; Qiu, Miao-Zhen MZ; Yang, Xin-Hua XH; Zhou, Da-Lei DL; Ma, Jiang-Jun JJ; Long, Ya-Kang YK; Ye, Zu-Lu ZL; Xu, Bo-Heng BH; Zhao, Qi Q; Jin, Ying Y; Lu, Shi-Xun SX; Wang, Zhi-Qiang ZQ; Guan, Wen-Long WL; Zhao, Bai-Wei BW; Zhou, Zhi-Wei ZW; Shao, Jian-Yong JY; Xu, Rui-Hua RH

Publication Date: 2020-01

Variant appearance in text: TP53: 1031T>C; Leu344Pro; rs121912662

PubMed Link: 32508039

Variant Present in the following documents:

• CTM2-10-353-s003.xlsx, sheet 3

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: TP53: L344P

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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Regulation of the MDM2-p53 pathway by the ubiquitin ligase HERC2.

Molecular Oncology

García-Cano, Jesús J; Sánchez-Tena, Susana S; Sala-Gaston, Joan J; Figueras, Agnès A; Viñals, Francesc F; Bartrons, Ramon R; Ventura, Francesc F; Rosa, Jose Luis JL

Publication Date: 2020-01

Variant appearance in text: p53: L344P

PubMed Link: 31665549

Variant Present in the following documents:

• Main text
• MOL2-14-69.pdf

View BVdb publication page

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Pan-cancer whole-genome analyses of metastatic solid tumours.

Nature

Priestley, Peter P; Baber, Jonathan J; Lolkema, Martijn P MP; Steeghs, Neeltje N; de Bruijn, Ewart E; Shale, Charles C; Duyvesteyn, Korneel K; Haidari, Susan S; van Hoeck, Arne A; Onstenk, Wendy W; Roepman, Paul P; Voda, Mircea M; Bloemendal, Haiko J HJ; Tjan-Heijnen, Vivianne C G VCG; van Herpen, Carla M L CML; Labots, Mariette M; Witteveen, Petronella O PO; Smit, Egbert F EF; Sleijfer, Stefan S; Voest, Emile E EE; Cuppen, Edwin E

Publication Date: 2019-11

Variant appearance in text: TP53: Leu344Pro

PubMed Link: 31645765

Variant Present in the following documents:

• 41586_2019_1689_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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The cancer-associated, gain-of-function TP53 variant P152Lp53 activates multiple signaling pathways implicated in tumorigenesis.

The Journal Of Biological Chemistry

Singh, Siddharth S; Kumar, Manoj M; Kumar, Sanjeev S; Sen, Shrinka S; Upadhyay, Pawan P; Bhattacharjee, Sayan S; M, Naveen N; Tomar, Vivek Singh VS; Roy, Siddhartha S; Dutt, Amit A; Kundu, Tapas K TK

Publication Date: 2019-09-20

Variant appearance in text: p53: L344P

PubMed Link: 31366730

Variant Present in the following documents:

• Main text

View BVdb publication page

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: TP53: L344P

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

View BVdb publication page

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From uncertainty to pathogenicity: clinical and functional interrogation of a rare TP53 in-frame deletion.

Cold Spring Harbor Molecular Case Studies

Quinn, Emily A EA; Maciaszek, Jamie L JL; Pinto, Emilia M EM; Phillips, Aaron H AH; Berdy, David D; Khandwala, Mohammad M; Upadhyaya, Santhosh A SA; Zambetti, Gerard P GP; Kriwacki, Richard W RW; Ellison, David W DW; Nichols, Kim E KE; Kesserwan, Chimene C

Publication Date: 2019-08

Variant appearance in text: TP53: 1031T>C; L344P

PubMed Link: 30886117

Variant Present in the following documents:

• supp_mcs.a003921_Supplemental_Table_1a.xlsx, sheet 1
• supp_mcs.a003921_Supplemental_Table_2.xlsx, sheet 1

View BVdb publication page

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Integrative molecular profiling identifies a novel cluster of estrogen receptor-positive breast cancer in very young women.

Cancer Science

Park, Charny C; Yoon, Kyong-Ah KA; Kim, Jihyun J; Park, In Hae IH; Park, Soo Jin SJ; Kim, Min Kyeong MK; Jang, Wooyeong W; Cho, Soo Young SY; Park, Boyoung B; Kong, Sun-Young SY; Lee, Eun Sook ES

Publication Date: 2019-05

Variant appearance in text: rs121912662

PubMed Link: 30811755

Variant Present in the following documents:

• CAS-110-1760-s002.xlsx, sheet 2

View BVdb publication page

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Assessing the Pathogenicity, Penetrance, and Expressivity of Putative Disease-Causing Variants in a Population Setting.

American Journal Of Human Genetics

Wright, Caroline F CF; West, Ben B; Tuke, Marcus M; Jones, Samuel E SE; Patel, Kashyap K; Laver, Thomas W TW; Beaumont, Robin N RN; Tyrrell, Jessica J; Wood, Andrew R AR; Frayling, Timothy M TM; Hattersley, Andrew T AT; Weedon, Michael N MN

Publication Date: 2019-02-07

Variant appearance in text: TP53: L344P; rs121912662

PubMed Link: 30665703

Variant Present in the following documents:

• mmc3.xlsx, sheet 1

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Wild-type p53 oligomerizes more efficiently than p53 hot-spot mutants and overcomes mutant p53 gain-of-function via a "dominant-positive" mechanism.

Oncotarget

Walerych, Dawid D; Pruszko, Magdalena M; Zyla, Lukasz L; Wezyk, Michalina M; Gaweda-Walerych, Katarzyna K; Zylicz, Alicja A

Publication Date: 2018-08-10

Variant appearance in text: p53: L344P

PubMed Link: 30174797

Variant Present in the following documents:

• Main text

View BVdb publication page

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Secondary Germline Finding in Liquid Biopsy of a Deceased Patient; Case Report and Review of the Literature.

Frontiers In Oncology

Veyseh, Maedah M; Ricker, Charite C; Espenschied, Carin C; Raymond, Victoria V; D'Souza, Anishka A; Barzi, Afsaneh A

Publication Date: 2018

Variant appearance in text: TP53: L344P

PubMed Link: 30050867

Variant Present in the following documents:

• Main text
• fonc-08-00259.pdf

View BVdb publication page

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A genome-wide screen of Epstein-Barr virus proteins that modulate host SUMOylation identifies a SUMO E3 ligase conserved in herpesviruses.

Plos Pathogens

De La Cruz-Herrera, Carlos F CF; Shire, Kathy K; Siddiqi, Umama Z UZ; Frappier, Lori L

Publication Date: 2018-07

Variant appearance in text: p53: L344P

PubMed Link: 29979787

Variant Present in the following documents:

• Main text

View BVdb publication page

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Association Between the Oligomeric Status of p53 and Clinical Outcomes in Li-Fraumeni Syndrome.

Journal Of The National Cancer Institute

Fischer, Nicholas W NW; Prodeus, Aaron A; Tran, James J; Malkin, David D; Gariépy, Jean J

Publication Date: 2018-12-01

Variant appearance in text: p53: L344P

PubMed Link: 29955864

Variant Present in the following documents:

• Main text

View BVdb publication page

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