TP53 c.997_998delinsGC ;(p.R333A)

Variant ID: 17-7574029-CG-GC

NM_000546.5(TP53):c.997_998delinsGC;(p.R333A)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Evolutionary action and structural basis of the allosteric switch controlling β2AR functional selectivity.

Nature Communications
Schönegge, Anne-Marie AM; Gallion, Jonathan J; Picard, Louis-Philippe LP; Wilkins, Angela D AD; Le Gouill, Christian C; Audet, Martin M; Stallaert, Wayne W; Lohse, Martin J MJ; Kimmel, Marek M; Lichtarge, Olivier O; Bouvier, Michel M
Publication Date: 2017-12-18

Variant appearance in text: TP53: R333A
PubMed Link: 29255305
Variant Present in the following documents:
  • 41467_2017_Article_2257.pdf
View BVdb publication page



Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology
Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B
Publication Date: 2014-10-28

Variant appearance in text: TP53: R333A
PubMed Link: 25348012
Variant Present in the following documents:
  • 13059_2014_484_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Nitration of the tumor suppressor protein p53 at tyrosine 327 promotes p53 oligomerization and activation.

Biochemistry
Yakovlev, Vasily A VA; Bayden, Alexander S AS; Graves, Paul R PR; Kellogg, Glen E GE; Mikkelsen, Ross B RB
Publication Date: 2010-06-29

Variant appearance in text: p53: Arg333Ala
PubMed Link: 20499882
Variant Present in the following documents:
  • Main text
View BVdb publication page