TP53 c.991_992delinsGC ;(p.Q331A)

Variant ID: 17-7576854-TG-GC

NM_000546.5(TP53):c.991_992delinsGC;(p.Q331A)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Targeting Mortalin by Embelin Causes Activation of Tumor Suppressor p53 and Deactivation of Metastatic Signaling in Human Breast Cancer Cells.

Plos One
Nigam, Nupur N; Grover, Abhinav A; Goyal, Sukriti S; Katiyar, Shashank P SP; Bhargava, Priyanshu P; Wang, Pi-Chao PC; Sundar, Durai D; Kaul, Sunil C SC; Wadhwa, Renu R
Publication Date: 2015

Variant appearance in text: p53: Q331A
PubMed Link: 26376435
Variant Present in the following documents:
  • Main text
  • pone.0138192.pdf
View BVdb publication page



Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology
Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B
Publication Date: 2014-10-28

Variant appearance in text: TP53: Q331A
PubMed Link: 25348012
Variant Present in the following documents:
  • 13059_2014_484_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Intermolecular β-strand networks avoid hub residues and favor low interconnectedness: a potential protection mechanism against chain dissociation upon mutation.

Plos One
Feverati, Giovanni G; Achoch, Mounia M; Vuillon, Laurent L; Lesieur, Claire C
Publication Date: 2014

Variant appearance in text: p53: Q331A
PubMed Link: 24733378
Variant Present in the following documents:
  • Main text
  • pone.0094745.pdf
View BVdb publication page



Parallel analysis of tetramerization domain mutants of the human p53 protein using PCR colonies.

Genomic Medicine
Merritt, Joshua J; Roberts, Kim G KG; Butz, James A JA; Edwards, Jeremy S JS
Publication Date: 2007

Variant appearance in text: p53: Gln331Ala
PubMed Link: 18923936
Variant Present in the following documents:
  • Main text
View BVdb publication page