Publications:

---

Deciphering the acetylation code of p53 in transcription regulation and tumor suppression.

Oncogene

Xia, Zhangchuan Z; Kon, Ning N; Gu, Alyssa P AP; Tavana, Omid O; Gu, Wei W

Publication Date: 2022-05

Variant appearance in text: p53: K320R

PubMed Link: 35487975

Variant Present in the following documents:

• nihms-1800386.pdf

View BVdb publication page

---

Nuclear NAD+ homeostasis governed by NMNAT1 prevents apoptosis of acute myeloid leukemia stem cells.

Science Advances

Shi, Xiangguo X; Jiang, Yajian Y; Kitano, Ayumi A; Hu, Tianyuan T; Murdaugh, Rebecca L RL; Li, Yuan Y; Hoegenauer, Kevin A KA; Chen, Rui R; Takahashi, Koichi K; Nakada, Daisuke D

Publication Date: 2021-07

Variant appearance in text: p53: K320R

PubMed Link: 34290089

Variant Present in the following documents:

• Main text
• abf3895.pdf

View BVdb publication page

---

Nuclear NAD+ homeostasis governed by NMNAT1 prevents apoptosis of acute myeloid leukemia stem cells.

Science Advances

Shi, Xiangguo X; Jiang, Yajian Y; Kitano, Ayumi A; Hu, Tianyuan T; Murdaugh, Rebecca L RL; Li, Yuan Y; Hoegenauer, Kevin A KA; Chen, Rui R; Takahashi, Koichi K; Nakada, Daisuke D

Publication Date: 2021-07

Variant appearance in text: p53: K320R

PubMed Link: 34290089

Variant Present in the following documents:

• Main text
• abf3895.pdf

View BVdb publication page

---

The mutational repertoire of uterine sarcomas and carcinosarcomas in a Brazilian cohort: A preliminary study.

Clinics (Sao Paulo, Brazil)

da Costa, Leonardo Tomiatti LT; Dos Anjos, Laura Gonzalez LG; Kagohara, Luciane Tsukamoto LT; Torrezan, Giovana Tardin GT; De Paula, Claudia A Andrade CAA; Baracat, Edmund Chada EC; Carraro, Dirce Maria DM; Carvalho, Katia Candido KC

Publication Date: 2021

Variant appearance in text: TP53: 959A>G

PubMed Link: 33503190

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Temporal and differential regulation of KAISO-controlled transcription by phosphorylated and acetylated p53 highlights a crucial regulatory role of apoptosis.

The Journal Of Biological Chemistry

Choi, Seo-Hyun SH; Koh, Dong-In DI; Cho, Su-Yeon SY; Kim, Min-Kyeong MK; Kim, Kyung-Sup KS; Hur, Man-Wook MW

Publication Date: 2019-08-30

Variant appearance in text: p53: K320R

PubMed Link: 31296660

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: TP53: K320R

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

View BVdb publication page

---

USP15-dependent lysosomal pathway controls p53-R175H turnover in ovarian cancer cells.

Nature Communications

Padmanabhan, Achuth A; Candelaria, Nicholes N; Wong, Kwong-Kwok KK; Nikolai, Bryan C BC; Lonard, David M DM; O'Malley, Bert W BW; Richards, JoAnne S JS

Publication Date: 2018-03-28

Variant appearance in text: p53: K320R

PubMed Link: 29593334

Variant Present in the following documents:

• 41467_2018_3599_MOESM1_ESM.pdf

View BVdb publication page

---

Germ-line and somatic EPHA2 coding variants in lens aging and cataract.

Plos One

Bennett, Thomas M TM; M'Hamdi, Oussama O; Hejtmancik, J Fielding JF; Shiels, Alan A

Publication Date: 2017

Variant appearance in text: TP53: K320R

PubMed Link: 29267365

Variant Present in the following documents:

• pone.0189881.s007.xlsx, sheet 2
• pone.0189881.s007.xlsx, sheet 3
• pone.0189881.s007.xlsx, sheet 1
• pone.0189881.s007.xlsx, sheet 4

View BVdb publication page

---

SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer's disease.

Aging Cell

Lee, Junghee J; Kim, Yunha Y; Liu, Tian T; Hwang, Yu Jin YJ; Hyeon, Seung Jae SJ; Im, Hyeonjoo H; Lee, Kyungeun K; Alvarez, Victor E VE; McKee, Ann C AC; Um, Soo-Jong SJ; Hur, Manwook M; Mook-Jung, Inhee I; Kowall, Neil W NW; Ryu, Hoon H

Publication Date: 2018-02

Variant appearance in text: p53: K320R

PubMed Link: 29130578

Variant Present in the following documents:

• Main text
• ACEL-17-na.pdf

View BVdb publication page

---

ID4 regulates transcriptional activity of wild type and mutant p53 via K373 acetylation.

Oncotarget

Morton, Derrick J DJ; Patel, Divya D; Joshi, Jugal J; Hunt, Aisha A; Knowell, Ashley E AE; Chaudhary, Jaideep J

Publication Date: 2017-01-10

Variant appearance in text: p53: K320R

PubMed Link: 27911860

Variant Present in the following documents:

• Main text
• oncotarget-08-2536.pdf

View BVdb publication page

---

iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports

Wang, Meng M; Wei, Liping L

Publication Date: 2016-08-16

Variant appearance in text: TP53: K320R

PubMed Link: 27527004

Variant Present in the following documents:

• srep31321-s5.xls, sheet 1

View BVdb publication page

---

Papillomavirus-Associated Tumor Formation Critically Depends on c-Fos Expression Induced by Viral Protein E2 and Bromodomain Protein Brd4.

Plos Pathogens

Delcuratolo, Maria M; Fertey, Jasmin J; Schneider, Markus M; Schuetz, Johanna J; Leiprecht, Natalie N; Hudjetz, Benjamin B; Brodbeck, Stephan S; Corall, Silke S; Dreer, Marcel M; Schwab, Roxana Michaela RM; Grimm, Martin M; Wu, Shwu-Yuan SY; Stubenrauch, Frank F; Chiang, Cheng-Ming CM; Iftner, Thomas T

Publication Date: 2016-01

Variant appearance in text: p53: K320R

PubMed Link: 26727473

Variant Present in the following documents:

• Main text
• ppat.1005366.pdf

View BVdb publication page

---

Histone Deacetylase (HDAC) Inhibitors - emerging roles in neuronal memory, learning, synaptic plasticity and neural regeneration.

Current Neuropharmacology

Ganai, Shabir Ahmad SA; Ramadoss, Mahalakshmi M; Mahadevan, Vijayalakshmi V

Publication Date: 2016

Variant appearance in text: p53: K320R

PubMed Link: 26487502

Variant Present in the following documents:

• Main text
• CN-14-55.pdf

View BVdb publication page

---

Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: TP53: K320R

PubMed Link: 25348012

Variant Present in the following documents:

• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

---

KAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genes.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Koh, Dong-In DI; Han, Dohyun D; Ryu, Hoon H; Choi, Won-Il WI; Jeon, Bu-Nam BN; Kim, Min-Kyeong MK; Kim, Youngsoo Y; Kim, Jin Young JY; Parry, Lee L; Clarke, Alan R AR; Reynolds, Albert B AB; Hur, Man-Wook MW

Publication Date: 2014-10-21

Variant appearance in text: p53: K320R

PubMed Link: 25288747

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Lysine-specific modifications of p53: a matter of life and death?

Oncotarget

Marouco, Diana D; Garabadgiu, Alexander V AV; Melino, Gerry G; Barlev, Nikolai A NA

Publication Date: 2013-10

Variant appearance in text: TP53: K320R

PubMed Link: 24298606

Variant Present in the following documents:

• Main text
• oncotarget-04-1556.pdf

View BVdb publication page

---

Unraveling the complexities of SIRT1-mediated mitochondrial regulation in skeletal muscle.

Exercise And Sport Sciences Reviews

Philp, Andrew A; Schenk, Simon S

Publication Date: 2013-07

Variant appearance in text: p53: K320R

PubMed Link: 23792490

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons.

The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience

Brochier, Camille C; Dennis, Gretel G; Rivieccio, Mark A MA; McLaughlin, Kathryn K; Coppola, Giovanni G; Ratan, Rajiv R RR; Langley, Brett B

Publication Date: 2013-05-15

Variant appearance in text: p53: K320R

PubMed Link: 23678107

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Altered binding site selection of p53 transcription cassettes by hepatitis B virus X protein.

Molecular And Cellular Biology

Chan, Cheryl C; Wang, Yu Y; Chow, Pierce K H PK; Chung, Alexander Y F AY; Ooi, London L P J LL; Lee, Caroline G CG

Publication Date: 2013-02

Variant appearance in text: p53: K320R

PubMed Link: 23149944

Variant Present in the following documents:

• Main text

View BVdb publication page

---

The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3.

Cell Cycle (Georgetown, Tex.)

Love, Ian M IM; Sekaric, Pedja P; Shi, Dingding D; Grossman, Steven R SR; Androphy, Elliot J EJ

Publication Date: 2012-07-01

Variant appearance in text: p53: K320R

PubMed Link: 22713239

Variant Present in the following documents:

• Main text

View BVdb publication page

---

p53 requires an intact C-terminal domain for DNA binding and transactivation.

Journal Of Molecular Biology

Kim, Hyunjung H; Kim, Kyunghwan K; Choi, Jongkyu J; Heo, Kyu K; Baek, Hwa Jin HJ; Roeder, Robert G RG; An, Woojin W

Publication Date: 2012-02-03

Variant appearance in text: p53: K320R

PubMed Link: 22178617

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Life or death: p53-induced apoptosis requires DNA binding cooperativity.

Cell Cycle (Georgetown, Tex.)

Schlereth, Katharina K; Charles, Joël P JP; Bretz, Anne C AC; Stiewe, Thorsten T

Publication Date: 2010-10-15

Variant appearance in text: p53: K320R

PubMed Link: 20948308

Variant Present in the following documents:

• Main text

View BVdb publication page

---

p53 post-translational modification: deregulated in tumorigenesis.

Trends In Molecular Medicine

Dai, Chao C; Gu, Wei W

Publication Date: 2010-11

Variant appearance in text: p53: K320R

PubMed Link: 20932800

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Quantitative proteomics analysis of the effects of ionizing radiation in wild type and p53 K317R knock-in mouse thymocytes.

Molecular & Cellular Proteomics : Mcp

Jenkins, Lisa M Miller LM; Mazur, Sharlyn J SJ; Rossi, Matteo M; Gaidarenko, Olga O; Xu, Yang Y; Appella, Ettore E

Publication Date: 2008-04

Variant appearance in text: p53: K320R

PubMed Link: 18178582

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Acetylation of mouse p53 at lysine 317 negatively regulates p53 apoptotic activities after DNA damage.

Molecular And Cellular Biology

Chao, Connie C; Wu, Zhiqun Z; Mazur, Sharlyn J SJ; Borges, Helena H; Rossi, Matteo M; Lin, Tongxiang T; Wang, Jean Y J JY; Anderson, Carl W CW; Appella, Ettore E; Xu, Yang Y

Publication Date: 2006-09

Variant appearance in text: p53: K320R

PubMed Link: 16943427

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters.

Molecular And Cellular Biology

Imbriano, Carol C; Gurtner, Aymone A; Cocchiarella, Fabienne F; Di Agostino, Silvia S; Basile, Valentina V; Gostissa, Monica M; Dobbelstein, Matthias M; Del Sal, Giannino G; Piaggio, Giulia G; Mantovani, Roberto R

Publication Date: 2005-05

Variant appearance in text: p53: K320R

PubMed Link: 15831478

Variant Present in the following documents:

• Main text

View BVdb publication page

---