Publications:

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Opposing roles of HDAC6 in liver regeneration and hepatocarcinogenesis.

Cancer Science

Phorl, Sophors S; Memon, Azra A; Seo, Yuri Y; Hoang, Thi Oanh TO; Tran, Trung Nghia TN; Nguyen, Le Minh Tri LMT; Lee, Chang Hoon CH; Lee, Woon Kyu WK; Lee, Joo-Yong JY

Publication Date: 2022-07

Variant appearance in text: p53: K320Q

PubMed Link: 35534985

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• Main text
• CAS-113-2311.pdf

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Temporal and differential regulation of KAISO-controlled transcription by phosphorylated and acetylated p53 highlights a crucial regulatory role of apoptosis.

The Journal Of Biological Chemistry

Choi, Seo-Hyun SH; Koh, Dong-In DI; Cho, Su-Yeon SY; Kim, Min-Kyeong MK; Kim, Kyung-Sup KS; Hur, Man-Wook MW

Publication Date: 2019-08-30

Variant appearance in text: p53: K320Q

PubMed Link: 31296660

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: TP53: K320Q

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

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SIRT3 deregulation is linked to mitochondrial dysfunction in Alzheimer's disease.

Aging Cell

Lee, Junghee J; Kim, Yunha Y; Liu, Tian T; Hwang, Yu Jin YJ; Hyeon, Seung Jae SJ; Im, Hyeonjoo H; Lee, Kyungeun K; Alvarez, Victor E VE; McKee, Ann C AC; Um, Soo-Jong SJ; Hur, Manwook M; Mook-Jung, Inhee I; Kowall, Neil W NW; Ryu, Hoon H

Publication Date: 2018-02

Variant appearance in text: p53: K320Q

PubMed Link: 29130578

Variant Present in the following documents:

• Main text
• ACEL-17-na.pdf

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ID4 regulates transcriptional activity of wild type and mutant p53 via K373 acetylation.

Oncotarget

Morton, Derrick J DJ; Patel, Divya D; Joshi, Jugal J; Hunt, Aisha A; Knowell, Ashley E AE; Chaudhary, Jaideep J

Publication Date: 2017-01-10

Variant appearance in text: p53: K320Q

PubMed Link: 27911860

Variant Present in the following documents:

• Main text
• oncotarget-08-2536.pdf

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iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports

Wang, Meng M; Wei, Liping L

Publication Date: 2016-08-16

Variant appearance in text: TP53: K320Q

PubMed Link: 27527004

Variant Present in the following documents:

• srep31321-s5.xls, sheet 1

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Sumoylation of HDAC2 promotes NF-κB-dependent gene expression.

Oncotarget

Wagner, Tobias T; Kiweler, Nicole N; Wolff, Katharina K; Knauer, Shirley K SK; Brandl, André A; Hemmerich, Peter P; Dannenberg, Jan-Hermen JH; Heinzel, Thorsten T; Schneider, Günter G; Krämer, Oliver H OH

Publication Date: 2015-03-30

Variant appearance in text: p53: K320Q

PubMed Link: 25704882

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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: TP53: K320Q

PubMed Link: 25348012

Variant Present in the following documents:

• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

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KAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genes.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Koh, Dong-In DI; Han, Dohyun D; Ryu, Hoon H; Choi, Won-Il WI; Jeon, Bu-Nam BN; Kim, Min-Kyeong MK; Kim, Youngsoo Y; Kim, Jin Young JY; Parry, Lee L; Clarke, Alan R AR; Reynolds, Albert B AB; Hur, Man-Wook MW

Publication Date: 2014-10-21

Variant appearance in text: p53: K320Q

PubMed Link: 25288747

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Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons.

The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience

Brochier, Camille C; Dennis, Gretel G; Rivieccio, Mark A MA; McLaughlin, Kathryn K; Coppola, Giovanni G; Ratan, Rajiv R RR; Langley, Brett B

Publication Date: 2013-05-15

Variant appearance in text: p53: K320Q

PubMed Link: 23678107

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Altered binding site selection of p53 transcription cassettes by hepatitis B virus X protein.

Molecular And Cellular Biology

Chan, Cheryl C; Wang, Yu Y; Chow, Pierce K H PK; Chung, Alexander Y F AY; Ooi, London L P J LL; Lee, Caroline G CG

Publication Date: 2013-02

Variant appearance in text: p53: K320Q

PubMed Link: 23149944

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Multiple transcription factor families regulate axon growth and regeneration.

Developmental Neurobiology

Moore, Darcie L DL; Goldberg, Jeffrey L JL

Publication Date: 2011-12

Variant appearance in text: p53: K320Q

PubMed Link: 21674813

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Life or death: p53-induced apoptosis requires DNA binding cooperativity.

Cell Cycle (Georgetown, Tex.)

Schlereth, Katharina K; Charles, Joël P JP; Bretz, Anne C AC; Stiewe, Thorsten T

Publication Date: 2010-10-15

Variant appearance in text: p53: K320Q

PubMed Link: 20948308

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Transcriptional regulation by p53.

Cold Spring Harbor Perspectives In Biology

Beckerman, Rachel R; Prives, Carol C

Publication Date: 2010-08

Variant appearance in text: p53: K320Q

PubMed Link: 20679336

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PCAF is an HIF-1alpha cofactor that regulates p53 transcriptional activity in hypoxia.

Oncogene

Xenaki, G G; Ontikatze, T T; Rajendran, R R; Stratford, I J IJ; Dive, C C; Krstic-Demonacos, M M; Demonacos, C C

Publication Date: 2008-10-02

Variant appearance in text: p53: K320Q

PubMed Link: 18574470

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Quantitative proteomics analysis of the effects of ionizing radiation in wild type and p53 K317R knock-in mouse thymocytes.

Molecular & Cellular Proteomics : Mcp

Jenkins, Lisa M Miller LM; Mazur, Sharlyn J SJ; Rossi, Matteo M; Gaidarenko, Olga O; Xu, Yang Y; Appella, Ettore E

Publication Date: 2008-04

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PubMed Link: 18178582

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The tumor suppressor protein p53 is required for neurite outgrowth and axon regeneration.

The Embo Journal

Di Giovanni, Simone S; Knights, Chad D CD; Rao, Mahadev M; Yakovlev, Alexander A; Beers, Jeannette J; Catania, Jason J; Avantaggiati, Maria Laura ML; Faden, Alan I AI

Publication Date: 2006-09-06

Variant appearance in text: p53: K320Q

PubMed Link: 16946709

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Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters.

Molecular And Cellular Biology

Imbriano, Carol C; Gurtner, Aymone A; Cocchiarella, Fabienne F; Di Agostino, Silvia S; Basile, Valentina V; Gostissa, Monica M; Dobbelstein, Matthias M; Del Sal, Giannino G; Piaggio, Giulia G; Mantovani, Roberto R

Publication Date: 2005-05

Variant appearance in text: p53: K320Q

PubMed Link: 15831478

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