TP53 c.902C>T ;(p.P301L)

Variant ID: 17-7577036-G-A

NM_000546.5(TP53):c.902C>T;(p.P301L)

This variant was identified in 130 publications

View GRCh38 version.




Publications:


Sirtuins at the Crossroads between Mitochondrial Quality Control and Neurodegenerative Diseases: Structure, Regulation, Modifications, and Modulators.

Aging And Disease
Xu, Hui H; Liu, Yi-Yang YY; Li, Lin-Seng LS; Liu, You-Shuo YS
Publication Date: 2023-06-01

Variant appearance in text: p53: P301L
PubMed Link: 37191431
Variant Present in the following documents:
  • Main text
  • ad-14-3-794.pdf
View BVdb publication page



Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy.

Nature Communications
Hussong, Stacy A SA; Banh, Andy Q AQ; Van Skike, Candice E CE; Dorigatti, Angela O AO; Hernandez, Stephen F SF; Hart, Matthew J MJ; Ferran, Beatriz B; Makhlouf, Haneen H; Gaczynska, Maria M; Osmulski, Pawel A PA; McAllen, Salome A SA; Dineley, Kelly T KT; Ungvari, Zoltan Z; Perez, Viviana I VI; Kayed, Rakez R; Galvan, Veronica V
Publication Date: 2023-04-25

Variant appearance in text: p53: P301L
PubMed Link: 37185259
Variant Present in the following documents:
  • 41467_2023_Article_37840.pdf
  • 41467_2023_37840_MOESM2_ESM.pdf
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The oDGal Mouse: A Novel, Physiologically Relevant Rodent Model of Sporadic Alzheimer's Disease.

International Journal Of Molecular Sciences
Chadwick, Wayne W; Maudsley, Stuart S; Hull, William W; Havolli, Enes E; Boshoff, Eugene E; Hill, Mark D W MDW; Goetghebeur, Pascal J D PJD; Harrison, David C DC; Nizami, Sohaib S; Bedford, David C DC; Coope, Gareth G; Real, Katia K; Thiemermann, Christoph C; Maycox, Peter P; Carlton, Mark M; Cole, Sarah L SL
Publication Date: 2023-04-09

Variant appearance in text: p53: P301L
PubMed Link: 37108119
Variant Present in the following documents:
  • ijms-24-06953.pdf
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The analytical Flory random coil is a simple-to-use reference model for unfolded and disordered proteins.

Biorxiv : The Preprint Server For Biology
Alston, Jhullian J JJ; Ginell, Garrett M GM; Soranno, Andrea A; Holehouse, Alex S AS
Publication Date: 2023-03-13

Variant appearance in text: p53: P301L
PubMed Link: 36993592
Variant Present in the following documents:
  • media-1.pdf
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24-Hydroxycholesterol Induces Tau Proteasome-Dependent Degradation via the SIRT1/PGC1α/Nrf2 Pathway: A Potential Mechanism to Counteract Alzheimer's Disease.

Antioxidants (Basel, Switzerland)
Testa, Gabriella G; Giannelli, Serena S; Sottero, Barbara B; Staurenghi, Erica E; Giaccone, Giorgio G; Caroppo, Paola P; Gamba, Paola P; Leonarduzzi, Gabriella G
Publication Date: 2023-03-03

Variant appearance in text: p53: P301L
PubMed Link: 36978879
Variant Present in the following documents:
  • antioxidants-12-00631.pdf
View BVdb publication page



An aging, pathology burden, and glial senescence build-up hypothesis for late onset Alzheimer's disease.

Nature Communications
Lau, Victor V; Ramer, Leanne L; Tremblay, Marie-Ève MÈ
Publication Date: 2023-03-25

Variant appearance in text: p53: P301L
PubMed Link: 36966157
Variant Present in the following documents:
  • 41467_2023_Article_37304.pdf
View BVdb publication page



Modeling Alzheimer's disease in primary neurons reveals DNA damage response coupled with MAPK-DLK signaling in wild-type tau-induced neurodegeneration.

Research Square
Li, Sanming S; Roy, Ethan R ER; Wang, Yanyu Y; Watkins, Trent T; Cao, Wei W
Publication Date: 2023-03-07

Variant appearance in text: p53: P301L
PubMed Link: 36945524
Variant Present in the following documents:
  • nihpp-rs2617457v1.pdf
View BVdb publication page



Natural Bioactive Molecules as Neuromedicines for the Treatment/Prevention of Neurodegenerative Diseases.

Acs Omega
Babazadeh, Afshin A; Vahed, Fereshteh Mohammadi FM; Liu, Qi Q; Siddiqui, Shahida Anusha SA; Kharazmi, Mohammad Saeed MS; Jafari, Seid Mahdi SM
Publication Date: 2023-01-31

Variant appearance in text: p53: P301L
PubMed Link: 36743024
Variant Present in the following documents:
  • ao2c06098.pdf
View BVdb publication page



A Low-Molecular-Weight BDNF Mimetic, Dipeptide GSB-214, Prevents Memory Impairment in Rat Models of Alzheimer's Disease.

Acta Naturae
Povarnina, P Yu PY; Volkova, A A AA; Vorontsova, O N ON; Kamensky, A A AA; Gudasheva, T A TA; Seredenin, S B SB
Publication Date: 2022

Variant appearance in text: p53: P301L
PubMed Link: 36694902
Variant Present in the following documents:
  • AN20758251-14-04-094.pdf
View BVdb publication page



The Important Role of Zinc in Neurological Diseases.

Biomolecules
Li, Zhe Z; Liu, Yang Y; Wei, Ruixue R; Yong, V Wee VW; Xue, Mengzhou M
Publication Date: 2022-12-23

Variant appearance in text: p53: P301L
PubMed Link: 36671413
Variant Present in the following documents:
  • Main text
  • biomolecules-13-00028.pdf
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Modulation of histone H3K4 dimethylation by spermidine ameliorates motor neuron survival and neuropathology in a mouse model of ALS.

Journal Of Biomedical Science
Choi, Seung-Hye SH; Yousefian-Jazi, Ali A; Hyeon, Seung Jae SJ; Nguyen, Phuong Thi Thanh PTT; Chu, Jiyeon J; Kim, Sojung S; Kim, Suhyun S; Ryu, Hannah L HL; Kowall, Neil W NW; Ryu, Hoon H; Lee, Junghee J
Publication Date: 2022-12-20

Variant appearance in text: p53: P301L
PubMed Link: 36536341
Variant Present in the following documents:
  • 12929_2022_Article_890.pdf
View BVdb publication page



Protein interactions: anything new?

Essays In Biochemistry
Barrera-Vilarmau, Susana S; Teixeira, João M C JMC; Fuxreiter, Monika M
Publication Date: 2022-11-23

Variant appearance in text: p53: P301L
PubMed Link: 36416856
Variant Present in the following documents:
  • Main text
  • ebc-66-ebc20220044.pdf
View BVdb publication page



Tau Protein as Therapeutic Target for Cancer? Focus on Glioblastoma.

Cancers
Hedna, Rayane R; Kovacic, Hervé H; Pagano, Alessandra A; Peyrot, Vincent V; Robin, Maxime M; Devred, François F; Breuzard, Gilles G
Publication Date: 2022-11-01

Variant appearance in text: p53: P301L
PubMed Link: 36358803
Variant Present in the following documents:
  • cancers-14-05386.pdf
View BVdb publication page



CK2 and protein kinases of the CK1 superfamily as targets for neurodegenerative disorders.

Frontiers In Molecular Biosciences
Baier, Andrea A; Szyszka, Ryszard R
Publication Date: 2022

Variant appearance in text: p53: P301L
PubMed Link: 36275622
Variant Present in the following documents:
  • fmolb-09-916063.pdf
View BVdb publication page



Aging-associated REGγ proteasome decline predisposes to tauopathy.

The Journal Of Biological Chemistry
Tu, Jialu J; Zhang, Haiyang H; Yang, Ting T; Liu, Yun Y; Kibreab, Solomon S; Zhang, Yunpeng Y; Gao, Liangcai L; Moses, Robb E RE; O'Malley, Bert W BW; Xiao, Jianru J; Li, Xiaotao X
Publication Date: 2022-11

Variant appearance in text: p53: P301L
PubMed Link: 36209822
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience
Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X
Publication Date: 2022-09-16

Variant appearance in text: p53: 902C>T
PubMed Link: 36117989
Variant Present in the following documents:
  • mmc4.xlsx, sheet 1
View BVdb publication page



Slingshot homolog-1 mediates the secretion of small extracellular vesicles containing misfolded proteins by regulating autophagy cargo receptors and actin dynamics.

Frontiers In Aging Neuroscience
Cazzaro, Sara S; Fang, Cenxiao C; Khan, Hirah H; Witas, Richard R; Kee, Teresa R TR; Woo, Jung-A A JA; Kang, David E DE
Publication Date: 2022

Variant appearance in text: p53: P301L
PubMed Link: 36092812
Variant Present in the following documents:
  • fnagi-14-933979.pdf
View BVdb publication page



Integrated cohort of esophageal squamous cell cancer reveals genomic features underlying clinical characteristics.

Nature Communications
Li, Minghao M; Zhang, Zicheng Z; Wang, Qianrong Q; Yi, Yan Y; Li, Baosheng B
Publication Date: 2022-09-07

Variant appearance in text: TP53: P301L
PubMed Link: 36071046
Variant Present in the following documents:
  • 41467_2022_32962_MOESM15_ESM.xlsx, sheet 22
View BVdb publication page



FAK-Mediated Signaling Controls Amyloid Beta Overload, Learning and Memory Deficits in a Mouse Model of Alzheimer's Disease.

International Journal Of Molecular Sciences
Saleh, Bisan B; Srikanth, Kolluru D KD; Sneh, Tal T; Yue, Lambert L; Pelech, Steven S; Elliott, Evan E; Gil-Henn, Hava H
Publication Date: 2022-08-13

Variant appearance in text: TP53: P301L
PubMed Link: 36012331
Variant Present in the following documents:
  • Main text
  • ijms-23-09055.pdf
View BVdb publication page



Synaptosome microRNAs regulate synapse functions in Alzheimer's disease.

Npj Genomic Medicine
Kumar, Subodh S; Orlov, Erika E; Gowda, Prashanth P; Bose, Chhanda C; Swerdlow, Russell H RH; Lahiri, Debomoy K DK; Reddy, P Hemachandra PH
Publication Date: 2022-08-08

Variant appearance in text: TP53: P301L
PubMed Link: 35941185
Variant Present in the following documents:
  • Main text
  • 41525_2022_Article_319.pdf
View BVdb publication page



Parkin as a Molecular Bridge Linking Alzheimer's and Parkinson's Diseases?

Biomolecules
Checler, Frédéric F; Alves da Costa, Cristine C
Publication Date: 2022-04-09

Variant appearance in text: p53: P301L
PubMed Link: 35454148
Variant Present in the following documents:
  • Main text
  • biomolecules-12-00559.pdf
View BVdb publication page



Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications
Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L
Publication Date: 2022-03-10

Variant appearance in text: TP53: 902C>T
PubMed Link: 35273153
Variant Present in the following documents:
  • 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research
Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL
Publication Date: 2022-05

Variant appearance in text: TP53: 902C>T; Pro301Leu
PubMed Link: 35229492
Variant Present in the following documents:
  • PCMR-35-369-s003.xlsx, sheet 6
View BVdb publication page



The Emergence of Model Systems to Investigate the Link Between Traumatic Brain Injury and Alzheimer's Disease.

Frontiers In Aging Neuroscience
Srinivasan, Gayathri G; Brafman, David A DA
Publication Date: 2021

Variant appearance in text: p53: P301L
PubMed Link: 35211003
Variant Present in the following documents:
  • Main text
  • fnagi-13-813544.pdf
View BVdb publication page



Antioxidants in Alzheimer's Disease: Current Therapeutic Significance and Future Prospects.

Biology
Pritam, Pingal P; Deka, Rahul R; Bhardwaj, Anuradha A; Srivastava, Rashi R; Kumar, Dhruv D; Jha, Abhimanyu Kumar AK; Jha, Niraj Kumar NK; Villa, Chiara C; Jha, Saurabh Kumar SK
Publication Date: 2022-01-28

Variant appearance in text: p53: P301L
PubMed Link: 35205079
Variant Present in the following documents:
  • Main text
  • biology-11-00212.pdf
View BVdb publication page



The interplay between oxidative stress and autophagy: focus on the development of neurological diseases.

Behavioral And Brain Functions : Bbf
Talebi, Marjan M; Mohammadi Vadoud, Seyyed Ali SA; Haratian, Alireza A; Talebi, Mohsen M; Farkhondeh, Tahereh T; Pourbagher-Shahri, Ali Mohammad AM; Samarghandian, Saeed S
Publication Date: 2022-01-29

Variant appearance in text: p53: P301L
PubMed Link: 35093121
Variant Present in the following documents:
  • Main text
View BVdb publication page



A New Insight into an Alternative Therapeutic Approach to Restore Redox Homeostasis and Functional Mitochondria in Neurodegenerative Diseases.

Antioxidants (Basel, Switzerland)
Hyun, Dong-Hoon DH; Lee, Jaewang J
Publication Date: 2021-12-21

Variant appearance in text: p53: P301L
PubMed Link: 35052511
Variant Present in the following documents:
  • Main text
  • antioxidants-11-00007.pdf
View BVdb publication page



A New Insight into an Alternative Therapeutic Approach to Restore Redox Homeostasis and Functional Mitochondria in Neurodegenerative Diseases.

Antioxidants (Basel, Switzerland)
Hyun, Dong-Hoon DH; Lee, Jaewang J
Publication Date: 2021-12-21

Variant appearance in text: p53: P301L
PubMed Link: 35052511
Variant Present in the following documents:
  • Main text
  • antioxidants-11-00007.pdf
View BVdb publication page



Ginsenoside Rd Attenuates Tau Phosphorylation in Olfactory Bulb, Spinal Cord, and Telencephalon by Regulating Glycogen Synthase Kinase 3β and Cyclin-Dependent Kinase 5.

Evidence-Based Complementary And Alternative Medicine : Ecam
Li, Ling L; Li, Tian T; Tian, Xin X; Zhao, Ling L
Publication Date: 2021

Variant appearance in text: p53: P301L
PubMed Link: 34987593
Variant Present in the following documents:
  • ECAM2021-4485957.pdf
View BVdb publication page



Insights into T-cell dysfunction in Alzheimer's disease.

Aging Cell
Dai, Linbin L; Shen, Yong Y
Publication Date: 2021-11-01

Variant appearance in text: TP53: P301L
PubMed Link: 34725916
Variant Present in the following documents:
  • ACEL-20-e13511.pdf
View BVdb publication page



Insights into T-cell dysfunction in Alzheimer's disease.

Aging Cell
Dai, Linbin L; Shen, Yong Y
Publication Date: 2021-12

Variant appearance in text: TP53: P301L
PubMed Link: 34725916
Variant Present in the following documents:
  • ACEL-20-e13511.pdf
View BVdb publication page



Novel Ubiquitin Specific Protease-13 Inhibitors Alleviate Neurodegenerative Pathology.

Metabolites
Liu, Xiaoguang X; Balaraman, Kaluvu K; Lynch, Ciarán C CC; Hebron, Michaeline M; Wolf, Christian C; Moussa, Charbel C
Publication Date: 2021-09-15

Variant appearance in text: p53: P301L
PubMed Link: 34564439
Variant Present in the following documents:
  • metabolites-11-00622.pdf
View BVdb publication page



Novel Therapies for Parkinsonian Syndromes-Recent Progress and Future Perspectives.

Frontiers In Molecular Neuroscience
Przewodowska, Dominika D; Marzec, Weronika W; Madetko, Natalia N
Publication Date: 2021

Variant appearance in text: p53: P301L
PubMed Link: 34512258
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Glyoxalase System in Age-Related Diseases: Nutritional Intervention as Anti-Ageing Strategy.

Cells
Aragonès, Gemma G; Rowan, Sheldon S; Francisco, Sarah G SG; Whitcomb, Elizabeth A EA; Yang, Wenxin W; Perini-Villanueva, Giuliana G; Schalkwijk, Casper G CG; Taylor, Allen A; Bejarano, Eloy E
Publication Date: 2021-07-22

Variant appearance in text: p53: P301L
PubMed Link: 34440621
Variant Present in the following documents:
  • Main text
  • cells-10-01852.pdf
View BVdb publication page



Autophagy and Tau Protein.

International Journal Of Molecular Sciences
Hamano, Tadanori T; Enomoto, Soichi S; Shirafuji, Norimichi N; Ikawa, Masamichi M; Yamamura, Osamu O; Yen, Shu-Hui SH; Nakamoto, Yasunari Y
Publication Date: 2021-07-12

Variant appearance in text: p53: P301L
PubMed Link: 34299093
Variant Present in the following documents:
  • Main text
  • ijms-22-07475.pdf
View BVdb publication page



A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.

Scientific Reports
Magraner-Pardo, Lorena L; Laskowski, Roman A RA; Pons, Tirso T; Thornton, Janet M JM
Publication Date: 2021-07-12

Variant appearance in text: TP53: 902C>T; Pro301Leu
PubMed Link: 34253785
Variant Present in the following documents:
  • 41598_2021_93715_MOESM2_ESM.xlsx, sheet 8
View BVdb publication page



UBE4B, a microRNA-9 target gene, promotes autophagy-mediated Tau degradation.

Nature Communications
Subramanian, Manivannan M; Hyeon, Seung Jae SJ; Das, Tanuza T; Suh, Yoon Seok YS; Kim, Yun Kyung YK; Lee, Jeong-Soo JS; Song, Eun Joo EJ; Ryu, Hoon H; Yu, Kweon K
Publication Date: 2021-06-02

Variant appearance in text: p53: P301L
PubMed Link: 34078905
Variant Present in the following documents:
  • Main text
  • 41467_2021_Article_23597.pdf
View BVdb publication page



Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice.

Nature Communications
Caballero, Benjamin B; Bourdenx, Mathieu M; Luengo, Enrique E; Diaz, Antonio A; Sohn, Peter Dongmin PD; Chen, Xu X; Wang, Chao C; Juste, Yves R YR; Wegmann, Susanne S; Patel, Bindi B; Young, Zapporah T ZT; Kuo, Szu Yu SY; Rodriguez-Navarro, Jose Antonio JA; Shao, Hao H; Lopez, Manuela G MG; Karch, Celeste M CM; Goate, Alison M AM; Gestwicki, Jason E JE; Hyman, Bradley T BT; Gan, Li L; Cuervo, Ana Maria AM
Publication Date: 2021-04-14

Variant appearance in text: p53: P301L
PubMed Link: 33854069
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mitochondrial Permeability Transition: A Pore Intertwines Brain Aging and Alzheimer's Disease.

Cells
Jia, Kun K; Du, Heng H
Publication Date: 2021-03-15

Variant appearance in text: p53: P301L
PubMed Link: 33804048
Variant Present in the following documents:
  • cells-10-00649.pdf
View BVdb publication page



Structural Proteomics Methods to Interrogate the Conformations and Dynamics of Intrinsically Disordered Proteins.

Frontiers In Chemistry
Beveridge, Rebecca R; Calabrese, Antonio N AN
Publication Date: 2021

Variant appearance in text: p53: P301L
PubMed Link: 33791275
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mitochondrial Dysfunction and Oxidative Stress in Alzheimer's Disease.

Frontiers In Aging Neuroscience
Misrani, Afzal A; Tabassum, Sidra S; Yang, Li L
Publication Date: 2021

Variant appearance in text: p53: P301L
PubMed Link: 33679375
Variant Present in the following documents:
  • Main text
View BVdb publication page



Human Induced Pluripotent Stem Cell-Derived Exosomes as a New Therapeutic Strategy for Various Diseases.

International Journal Of Molecular Sciences
Wang, Aline Yen Ling AYL
Publication Date: 2021-02-10

Variant appearance in text: p53: P301L
PubMed Link: 33578948
Variant Present in the following documents:
  • Main text
View BVdb publication page



Isoform-selective decrease of glycogen synthase kinase-3-beta (GSK-3β) reduces synaptic tau phosphorylation, transcellular spreading, and aggregation.

Iscience
Amaral, Ana Claudia AC; Perez-Nievas, Beatriz G BG; Siao Tick Chong, Michael M; Gonzalez-Martinez, Alicia A; Argente-Escrig, Herminia H; Rubio-Guerra, Sara S; Commins, Caitlin C; Muftu, Serra S; Eftekharzadeh, Bahareh B; Hudry, Eloise E; Fan, Zhanyun Z; Ramanan, Prianca P; Takeda, Shuko S; Frosch, Matthew P MP; Wegmann, Susanne S; Gomez-Isla, Teresa T
Publication Date: 2021-02-19

Variant appearance in text: p53: P301L
PubMed Link: 33554064
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



The Synaptic Dysregulation in Adolescent Rats Exposed to Maternal Immune Activation.

Frontiers In Molecular Neuroscience
Cieślik, Magdalena M; Gassowska-Dobrowolska, Magdalena M; Zawadzka, Aleksandra A; Frontczak-Baniewicz, Małgorzata M; Gewartowska, Magdalena M; Dominiak, Agnieszka A; Czapski, Grzegorz A GA; Adamczyk, Agata A
Publication Date: 2020

Variant appearance in text: p53: P301L
PubMed Link: 33519375
Variant Present in the following documents:
  • fnmol-13-555290.pdf
View BVdb publication page



Tau Oligomers Neurotoxicity.

Life (Basel, Switzerland)
Niewiadomska, Grazyna G; Niewiadomski, Wiktor W; Steczkowska, Marta M; Gasiorowska, Anna A
Publication Date: 2021-01-06

Variant appearance in text: p53: P301L
PubMed Link: 33418848
Variant Present in the following documents:
  • Main text
View BVdb publication page



Tau and DNA Damage in Neurodegeneration.

Brain Sciences
Colnaghi, Luca L; Rondelli, Diego D; Muzi-Falconi, Marco M; Sertic, Sarah S
Publication Date: 2020-12-07

Variant appearance in text: p53: P301L
PubMed Link: 33297375
Variant Present in the following documents:
  • brainsci-10-00946.pdf
View BVdb publication page



Functional Foods: An Approach to Modulate Molecular Mechanisms of Alzheimer's Disease.

Cells
Atlante, Anna A; Amadoro, Giuseppina G; Bobba, Antonella A; Latina, Valentina V
Publication Date: 2020-10-23

Variant appearance in text: p53: P301L
PubMed Link: 33114170
Variant Present in the following documents:
  • Main text
View BVdb publication page



Nuclear Transport Deficits in Tau-Related Neurodegenerative Diseases.

Frontiers In Neurology
Diez, Lisa L; Wegmann, Susanne S
Publication Date: 2020

Variant appearance in text: p53: P301L
PubMed Link: 33101165
Variant Present in the following documents:
  • Main text
  • fneur-11-01056.pdf
View BVdb publication page



Effect of rapamycin on aging and age-related diseases-past and future.

Geroscience
Selvarani, Ramasamy R; Mohammed, Sabira S; Richardson, Arlan A
Publication Date: 2021-06

Variant appearance in text: p53: P301L
PubMed Link: 33037985
Variant Present in the following documents:
  • Main text
View BVdb publication page



Interleukin-1β Drives Cellular Senescence of Rat Astrocytes Induced by Oligomerized Amyloid β Peptide and Oxidative Stress.

Frontiers In Neurology
Shang, Dongsheng D; Hong, Yin Y; Xie, Wangwang W; Tu, Zhigang Z; Xu, Jun J
Publication Date: 2020

Variant appearance in text: p53: P301L
PubMed Link: 33013631
Variant Present in the following documents:
  • Main text
  • fneur-11-00929.pdf
View BVdb publication page



Neuroprotective effects of p62(SQSTM1)-engineered lactic acid bacteria in Alzheimer's disease: a pre-clinical study.

Aging
Cecarini, Valentina V; Bonfili, Laura L; Gogoi, Olee O; Lawrence, Solomon S; Venanzi, Franco M FM; Azevedo, Vasco V; Mancha-Agresti, Pamela P; Drumond, Mariana Martins MM; Rossi, Giacomo G; Berardi, Sara S; Galosi, Livio L; Cuccioloni, Massimiliano M; Angeletti, Mauro M; Suchodolski, Jan S JS; Pilla, Rachel R; Lidbury, Jonathan A JA; Eleuteri, Anna Maria AM
Publication Date: 2020-08-28

Variant appearance in text: p53: P301L
PubMed Link: 32855357
Variant Present in the following documents:
  • Main text
View BVdb publication page



Protein phase separation: A novel therapy for cancer?

British Journal Of Pharmacology
Wang, Wei W; Chen, Yingqian Y; Xu, Aixiao A; Cai, Minyi M; Cao, Ji J; Zhu, Hong H; Yang, Bo B; Shao, Xuejing X; Ying, Meidan M; He, Qiaojun Q
Publication Date: 2020-11

Variant appearance in text: p53: P301L
PubMed Link: 32851637
Variant Present in the following documents:
  • Main text
View BVdb publication page



P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer's disease.

Acta Neuropathologica Communications
Farmer, Kathleen M KM; Ghag, Gaurav G; Puangmalai, Nicha N; Montalbano, Mauro M; Bhatt, Nemil N; Kayed, Rakez R
Publication Date: 2020-08-10

Variant appearance in text: p53: P301L
PubMed Link: 32778161
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Role of BMI1 in Late-Onset Sporadic Alzheimer's Disease.

Genes
Hogan, Ryan R; Flamier, Anthony A; Nardini, Eleonora E; Bernier, Gilbert G
Publication Date: 2020-07-21

Variant appearance in text: p53: P301L
PubMed Link: 32708145
Variant Present in the following documents:
  • Main text
View BVdb publication page



Interaction of Oxidative Stress and Misfolded Proteins in the Mechanism of Neurodegeneration.

Life (Basel, Switzerland)
Abramov, Andrey Y AY; Potapova, Elena V EV; Dremin, Viktor V VV; Dunaev, Andrey V AV
Publication Date: 2020-06-30

Variant appearance in text: p53: P301L
PubMed Link: 32629809
Variant Present in the following documents:
  • Main text
View BVdb publication page



cGMP via PKG activates 26S proteasomes and enhances degradation of proteins, including ones that cause neurodegenerative diseases.

Proceedings Of The National Academy Of Sciences Of The United States Of America
VerPlank, Jordan J S JJS; Tyrkalska, Sylwia D SD; Fleming, Angeleen A; Rubinsztein, David C DC; Goldberg, Alfred L AL
Publication Date: 2020-06-23

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PubMed Link: 32513741
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Transplantation of bone marrow mesenchymal stem cells improves cognitive deficits and alleviates neuropathology in animal models of Alzheimer's disease: a meta-analytic review on potential mechanisms.

Translational Neurodegeneration
Qin, Chuan C; Lu, Yalan Y; Wang, Kewei K; Bai, Lin L; Shi, Guiying G; Huang, Yiying Y; Li, Yongning Y
Publication Date: 2020-05-27

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PubMed Link: 32460886
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White matter alterations in Alzheimer's disease without concomitant pathologies.

Neuropathology And Applied Neurobiology
Ferrer, I I; Andrés-Benito, P P
Publication Date: 2020-12

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PubMed Link: 32255227
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Tau protein- induced sequestration of the eukaryotic ribosome: Implications in neurodegenerative disease.

Scientific Reports
Banerjee, Senjuti S; Ferdosh, Sehnaz S; Ghosh, Amar Nath AN; Barat, Chandana C
Publication Date: 2020-03-23

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PubMed Link: 32251304
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The PERK-Dependent Molecular Mechanisms as a Novel Therapeutic Target for Neurodegenerative Diseases.

International Journal Of Molecular Sciences
Rozpędek-Kamińska, Wioletta W; Siwecka, Natalia N; Wawrzynkiewicz, Adam A; Wojtczak, Radosław R; Pytel, Dariusz D; Diehl, J Alan JA; Majsterek, Ireneusz I
Publication Date: 2020-03-19

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PubMed Link: 32204380
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Post-translational Modifications of the Peptidyl-Prolyl Isomerase Pin1.

Frontiers In Cell And Developmental Biology
Chen, Dongmei D; Wang, Long L; Lee, Tae Ho TH
Publication Date: 2020

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PubMed Link: 32195254
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"Amyloid-beta accumulation cycle" as a prevention and/or therapy target for Alzheimer's disease.

Aging Cell
Rao, Chinthalapally V CV; Asch, Adam S AS; Carr, Daniel J J DJJ; Yamada, Hiroshi Y HY
Publication Date: 2020-03

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PubMed Link: 31981470
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Knockout of p75 neurotrophin receptor attenuates the hyperphosphorylation of Tau in pR5 mouse model.

Aging
Mañucat-Tan, Noralyn B NB; Shen, Lin-Lin LL; Bobrovskaya, Larisa L; Al-Hawwas, Mohammed M; Zhou, Fiona H FH; Wang, Yan-Jiang YJ; Zhou, Xin-Fu XF
Publication Date: 2019-09-03

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PubMed Link: 31479419
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Neuroprotective Approach of Anti-Cancer Microtubule Stabilizers Against Tauopathy Associated Dementia: Current Status of Clinical and Preclinical Findings.

Journal Of Alzheimer'S Disease Reports
Duggal, Pallavi P; Mehan, Sidharth S
Publication Date: 2019-07-02

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PubMed Link: 31435618
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