TP53 c.846_848del ;(p.R283del)

Variant ID: 17-7577089-GCGC-G

NM_000546.5(TP53):c.846_848del;(p.R283del)

This variant was identified in 11 publications

View GRCh38 version.




Publications:


Integrated cohort of esophageal squamous cell cancer reveals genomic features underlying clinical characteristics.

Nature Communications
Li, Minghao M; Zhang, Zicheng Z; Wang, Qianrong Q; Yi, Yan Y; Li, Baosheng B
Publication Date: 2022-09-07

Variant appearance in text: TP53: 846_848del; R283del
PubMed Link: 36071046
Variant Present in the following documents:
  • 41467_2022_32962_MOESM15_ESM.xlsx, sheet 22
View BVdb publication page



Dualistic classification of high grade serous ovarian carcinoma has its root in spatial heterogeneity.

Journal Of Advanced Research
Sun, Tingting T; Zhang, Zuwei Z; Tian, Liming L; Zheng, Yu Y; Wu, Linxiang L; Guo, Yunyun Y; Li, Xiaohui X; Li, Yuanyuan Y; Shen, Hongwei H; Lai, Yingrong Y; Liu, Junfeng J; Cui, Huanhuan H; He, Shasha S; Ren, Yufeng Y; Yang, Guofen G
Publication Date: 2022-08-28

Variant appearance in text: TP53: 846_848del
PubMed Link: 36038111
Variant Present in the following documents:
  • mmc2.xlsx, sheet 4
View BVdb publication page



Nivolumab in combination with cabozantinib for metastatic triple-negative breast cancer: a phase II and biomarker study.

Npj Breast Cancer
Barroso-Sousa, Romualdo R; Keenan, Tanya E TE; Li, Tianyu T; Tayob, Nabihah N; Trippa, Lorenzo L; Pastorello, Ricardo G RG; Richardson Iii, Edward T ET; Dillon, Deborah D; Amoozgar, Zohreh Z; Overmoyer, Beth B; Schnitt, Stuart J SJ; Winer, Eric P EP; Mittendorf, Elizabeth A EA; Van Allen, Eliezer E; Duda, Dan G DG; Tolaney, Sara M SM
Publication Date: 2021-08-25

Variant appearance in text: TP53: R282del
PubMed Link: 34433812
Variant Present in the following documents:
  • 41523_2021_287_MOESM1_ESM.xlsx, sheet 6
View BVdb publication page



Development and validation of a multigene variant profiling assay to guide targeted and immuno therapy selection in solid tumors.

Plos One
Akolkar, Dadasaheb D; Patil, Darshana D; Srivastava, Navin N; Patil, Revati R; Datta, Vineet V; Apurwa, Sachin S; Yashwante, Nitin N; Dhasarathan, Raja R; Gosavi, Rahul R; John, Jinumary J; Khan, Shabishta S; Jadhav, Ninad N; Mene, Priti P; Ahire, Dhanashri D; Pawar, Sushant S; Bodke, Harshal H; Sahoo, Subhraline S; Nile, Arun A; Saindane, Dinesh D; Darokar, Harshal H; Devhare, Pradip P; Srinivasan, Ajay A; Datar, Rajan R
Publication Date: 2021

Variant appearance in text: TP53: R282del
PubMed Link: 33556149
Variant Present in the following documents:
  • pone.0246048.s008.xlsx, sheet 1
View BVdb publication page



Identification of relevant genetic alterations in cancer using topological data analysis.

Nature Communications
Rabadán, Raúl R; Mohamedi, Yamina Y; Rubin, Udi U; Chu, Tim T; Alghalith, Adam N AN; Elliott, Oliver O; Arnés, Luis L; Cal, Santiago S; Obaya, Álvaro J ÁJ; Levine, Arnold J AJ; Cámara, Pablo G PG
Publication Date: 2020-07-30

Variant appearance in text: TP53: R282del
PubMed Link: 32732999
Variant Present in the following documents:
  • 41467_2020_17659_MOESM3_ESM.xls, sheet 1
View BVdb publication page



Impact of TP53 mutations in breast cancer: Clinicopathological features and prognosisImpact of TP53 mutations in breast CA.

Thoracic Cancer
Li, Xuerui X; Chen, Xiaoqing X; Wen, Lingzhu L; Wang, Yulei Y; Chen, Bo B; Xue, Yunlian Y; Guo, Liping L; Liao, Ning N
Publication Date: 2020-07

Variant appearance in text: TP53: R282del
PubMed Link: 32412177
Variant Present in the following documents:
  • Main text
  • TCA-11-1861.pdf
View BVdb publication page



Optimized p53 immunohistochemistry is an accurate predictor of TP53 mutation in ovarian carcinoma.

The Journal Of Pathology. Clinical Research
Köbel, Martin M; Piskorz, Anna M AM; Lee, Sandra S; Lui, Shuhong S; LePage, Cecile C; Marass, Francesco F; Rosenfeld, Nitzan N; Mes Masson, Anne-Marie AM; Brenton, James D JD
Publication Date: 2016-10

Variant appearance in text: TP53: R282del
PubMed Link: 27840695
Variant Present in the following documents:
  • CJP2-2-247-s010.xlsx, sheet 1
View BVdb publication page



A Landscape of Pharmacogenomic Interactions in Cancer.

Cell
Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ
Publication Date: 2016-07-28

Variant appearance in text: TP53: 846_848delGCG
PubMed Link: 27397505
Variant Present in the following documents:
  • mmc3.xlsx, sheet 3
View BVdb publication page



REGene: a literature-based knowledgebase of animal regeneration that bridge tissue regeneration and cancer.

Scientific Reports
Zhao, Min M; Rotgans, Bronwyn B; Wang, Tianfang T; Cummins, S F SF
Publication Date: 2016-03-15

Variant appearance in text: TP53: R282del
PubMed Link: 26975833
Variant Present in the following documents:
  • srep23167-s9.xls, sheet 1
View BVdb publication page



Mutational and gene fusion analyses of primary large cell and large cell neuroendocrine lung cancer.

Oncotarget
Karlsson, Anna A; Brunnström, Hans H; Lindquist, Kajsa Ericson KE; Jirström, Karin K; Jönsson, Mats M; Rosengren, Frida F; Reuterswärd, Christel C; Cirenajwis, Helena H; Borg, Åke Å; Jönsson, Per P; Planck, Maria M; Jönsson, Göran G; Staaf, Johan J
Publication Date: 2015-09-08

Variant appearance in text: TP53: Arg282del
PubMed Link: 26124082
Variant Present in the following documents:
  • oncotarget-06-22028-s004.xlsx, sheet 3
View BVdb publication page



Ice-COLD-PCR enables rapid amplification and robust enrichment for low-abundance unknown DNA mutations.

Nucleic Acids Research
Milbury, Coren A CA; Li, Jin J; Makrigiorgos, G Mike GM
Publication Date: 2011-01

Variant appearance in text: TP53: Arg282del
PubMed Link: 20937629
Variant Present in the following documents:
  • Main text
  • supp_gkq899_nar-01560-met-g-2010-File006.pdf
  • gkq899.pdf
View BVdb publication page