TP53 c.817_819delinsTGG ;(p.R273W)

Variant ID: 17-7577119-ACG-CCA

NM_000546.5(TP53):c.817_819delinsTGG;(p.R273W)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Assessment of Thermal Stability of Mutant p53 Proteins via Differential Scanning Fluorimetry.

Life (Basel, Switzerland)
Khadiullina, Raniya R; Mirgayazova, Regina R; Davletshin, Damir D; Khusainova, Elvina E; Chasov, Vitaly V; Bulatov, Emil E
Publication Date: 2022-12-22

Variant appearance in text: p53: R273W
PubMed Link: 36675980
Variant Present in the following documents:
  • Main text
  • life-13-00031.pdf
View BVdb publication page



In Vitro CRISPR-Cas12a-Based Detection of Cancer-Associated TP53 Hotspot Mutations Beyond the crRNA Seed Region.

The Crispr Journal
Kohabir, Kavish A V KAV; Nooi, Lars O LO; Brink, Arjen A; Brakenhoff, Ruud H RH; Sistermans, Erik A EA; Wolthuis, Rob M F RMF
Publication Date: 2023-01-13

Variant appearance in text: TP53: R273w
PubMed Link: 36637878
Variant Present in the following documents:
  • Main text
  • crispr.2022.0077.pdf
View BVdb publication page



TP53 in Biology and Treatment of Osteosarcoma.

Cancers
Synoradzki, Kamil Jozef KJ; Bartnik, Ewa E; Czarnecka, Anna M AM; Fiedorowicz, Michał M; Firlej, Wiktoria W; Brodziak, Anna A; Stasinska, Agnieszka A; Rutkowski, Piotr P; Grieb, Paweł P
Publication Date: 2021-08-25

Variant appearance in text: p53: R273W
PubMed Link: 34503094
Variant Present in the following documents:
  • Main text
  • cancers-13-04284.pdf
View BVdb publication page



Diffuse large B-cell lymphoma with combined TP53 mutation and MIR34A methylation: Another "double hit" lymphoma with very poor outcome?

Oncotarget
Asmar, Fazila F; Hother, Christoffer C; Kulosman, Gorjan G; Treppendahl, Marianne Bach MB; Nielsen, Helene Myrtue HM; Ralfkiaer, Ulrik U; Pedersen, Anja A; Møller, Michael Boe MB; Ralfkiaer, Elisabeth E; de Nully Brown, Peter P; Grønbæk, Kirsten K
Publication Date: 2014-04-15

Variant appearance in text: TP53: R273W
PubMed Link: 24722400
Variant Present in the following documents:
  • oncotarget-05-1912-s001.pdf
View BVdb publication page



Allele-specific p53 mutant reactivation.

Cancer Cell
Yu, Xin X; Vazquez, Alexei A; Levine, Arnold J AJ; Carpizo, Darren R DR
Publication Date: 2012-05-15

Variant appearance in text: p53: R273W
PubMed Link: 22624712
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mutant p53 attenuates the SMAD-dependent transforming growth factor beta1 (TGF-beta1) signaling pathway by repressing the expression of TGF-beta receptor type II.

Molecular And Cellular Biology
Kalo, Eyal E; Buganim, Yosef Y; Shapira, Keren E KE; Besserglick, Hilla H; Goldfinger, Naomi N; Weisz, Lilach L; Stambolsky, Perry P; Henis, Yoav I YI; Rotter, Varda V
Publication Date: 2007-12

Variant appearance in text: p53: R273W
PubMed Link: 17875924
Variant Present in the following documents:
  • Main text
View BVdb publication page