TP53 c.817_819delinsAAG ;(p.R273K)

Variant ID: 17-7577119-ACG-CTT

NM_000546.5(TP53):c.817_819delinsAAG;(p.R273K)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


The mutational landscape of cancer's vulnerability to ionizing radiation.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Gopal, Priyanka P; Yard, Brian D BD; Petty, Aaron A; Lal, Jessica C JC; Bera, Titas K TK; Hoang, Trung Q TQ; Buhimschi, Alexandru B AB; Abazeed, Mohamed E ME
Publication Date: 2022-10-12

Variant appearance in text: TP53: R273K
PubMed Link: 36222846
Variant Present in the following documents:
  • ccr-22-1914_supplementary_data_3_suppds3.xlsx, sheet 1
  • ccr-22-1914_supplementary_data_2_suppds2.xlsx, sheet 1
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: TP53: R273K
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Δ133p53β isoform pro-invasive activity is regulated through an aggregation-dependent mechanism in cancer cells.

Nature Communications
Arsic, Nikola N; Slatter, Tania T; Gadea, Gilles G; Villain, Etienne E; Fournet, Aurelie A; Kazantseva, Marina M; Allemand, Frédéric F; Sibille, Nathalie N; Seveno, Martial M; de Rossi, Sylvain S; Mehta, Sunali S; Urbach, Serge S; Bourdon, Jean-Christophe JC; Bernado, Pau P; Kajava, Andrey V AV; Braithwaite, Antony A; Roux, Pierre P
Publication Date: 2021-09-15

Variant appearance in text: p53: R273K
PubMed Link: 34526502
Variant Present in the following documents:
  • 41467_2021_25550_MOESM1_ESM.pdf
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: TP53: R273K
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
View BVdb publication page



Clinical Applications and Utility of a Precision Medicine Approach for Patients With Unexplained Cytopenias.

Mayo Clinic Proceedings
Mangaonkar, Abhishek A AA; Ferrer, Alejandro A; Pinto E Vairo, Filippo F; Cousin, Margot A MA; Kuisle, Ryan J RJ; Gangat, Naseema N; Hogan, William J WJ; Litzow, Mark R MR; McAllister, Tammy M TM; Klee, Eric W EW; Lazaridis, Konstantinos N KN; Stewart, A Keith AK; Patnaik, Mrinal M MM
Publication Date: 2019-09

Variant appearance in text: TP53: Arg273Lys
PubMed Link: 31256854
Variant Present in the following documents:
  • Main text
View BVdb publication page



Salvation of the fallen angel: Reactivating mutant p53.

British Journal Of Pharmacology
Li, Yang Y; Wang, Zhuoyi Z; Chen, Yuchen Y; Petersen, Robert B RB; Zheng, Ling L; Huang, Kun K
Publication Date: 2019-04

Variant appearance in text: p53: R273K
PubMed Link: 30632144
Variant Present in the following documents:
  • Main text
View BVdb publication page



Recurrent inactivating RASA2 mutations in melanoma.

Nature Genetics
Arafeh, Rand R; Qutob, Nouar N; Emmanuel, Rafi R; Keren-Paz, Alona A; Madore, Jason J; Elkahloun, Abdel A; Wilmott, James S JS; Gartner, Jared J JJ; Di Pizio, Antonella A; Winograd-Katz, Sabina S; Sindiri, Sivasish S; Rotkopf, Ron R; Dutton-Regester, Ken K; Johansson, Peter P; Pritchard, Antonia L AL; Waddell, Nicola N; Hill, Victoria K VK; Lin, Jimmy C JC; Hevroni, Yael Y; Rosenberg, Steven A SA; Khan, Javed J; Ben-Dor, Shifra S; Niv, Masha Y MY; Ulitsky, Igor I; Mann, Graham J GJ; Scolyer, Richard A RA; Hayward, Nicholas K NK; Samuels, Yardena Y
Publication Date: 2015-12

Variant appearance in text: TP53: R273K
PubMed Link: 26502337
Variant Present in the following documents:
  • NIHMS65345-supplement-Supplementary_table_3.xlsx, sheet 2
View BVdb publication page



Active Akt and functional p53 modulate apoptosis in Abelson virus-transformed pre-B cells.

Journal Of Virology
Gong, Li L; Unnikrishnan, Indira I; Raghavan, Anuradha A; Parmar, Kalindi K; Rosenberg, Naomi N
Publication Date: 2004-02

Variant appearance in text: p53: R273K
PubMed Link: 14747529
Variant Present in the following documents:
  • Main text
View BVdb publication page



Absence of p53 complements defects in Abelson murine leukemia virus signaling.

Journal Of Virology
Unnikrishnan, Indira I; Rosenberg, Naomi N
Publication Date: 2003-06

Variant appearance in text: p53: R273K
PubMed Link: 12743277
Variant Present in the following documents:
  • Main text
View BVdb publication page



Temperature-sensitive transformation by an Abelson virus mutant encoding an altered SH2 domain.

Journal Of Virology
Mainville, C A CA; Parmar, K K; Unnikrishnan, I I; Gong, L L; Raffel, G D GD; Rosenberg, N N
Publication Date: 2001-02

Variant appearance in text: p53: R273K
PubMed Link: 11160680
Variant Present in the following documents:
  • Main text
View BVdb publication page