Variant ID: 17-7577120-C-T

NM_000546.5(TP53):c.818G>A;(p.R273H)

This variant was identified in 1930 publications

View GRCh38 version.




Publications:


Convergent evolution and multi-wave clonal invasion in H3 K27-altered diffuse midline gliomas treated with a PDGFR inhibitor.

Acta Neuropathologica Communications
Arunachalam, Sasi S; Szlachta, Karol K; Brady, Samuel W SW; Ma, Xiaotu X; Ju, Bensheng B; Shaner, Bridget B; Mulder, Heather L HL; Easton, John J; Raphael, Benjamin J BJ; Myers, Matthew M; Tinkle, Christopher C; Allen, Sariah J SJ; Orr, Brent A BA; Wetmore, Cynthia J CJ; Baker, Suzanne J SJ; Zhang, Jinghui J
Publication Date: 2022-05-31

Variant appearance in text: TP53: R273H
PubMed Link: 35642016
Variant Present in the following documents:
  • Main text
  • 40478_2022_Article_1381.pdf
  • 40478_2022_1381_MOESM2_ESM.pdf
View BVdb publication page



Butyrate Inhibits Colorectal Cancer Cell Proliferation through Autophagy Degradation of β-Catenin Regardless of APC and β-Catenin Mutational Status.

Biomedicines
Garavaglia, Beatrice B; Vallino, Letizia L; Ferraresi, Alessandra A; Esposito, Andrea A; Salwa, Amreen A; Vidoni, Chiara C; Gentilli, Sergio S; Isidoro, Ciro C
Publication Date: 2022-05-13

Variant appearance in text: TP53: R273H
PubMed Link: 35625868
Variant Present in the following documents:
  • biomedicines-10-01131.pdf
View BVdb publication page



The Emerging Roles and Therapeutic Implications of Epigenetic Modifications in Ovarian Cancer.

Frontiers In Endocrinology
Wang, Yu Y; Huang, Zhao Z; Li, Bowen B; Liu, Lin L; Huang, Canhua C
Publication Date: 2022

Variant appearance in text: p53: R273H
PubMed Link: 35620395
Variant Present in the following documents:
  • fendo-13-863541.pdf
View BVdb publication page



Pathophysiologic and clinical implications of molecular profiles resultant from deletion 5q.

Ebiomedicine
Adema, Vera V; Palomo, Laura L; Walter, Wencke W; Mallo, Mar M; Hutter, Stephan S; La Framboise, Thomas T; Arenillas, Leonor L; Meggendorfer, Manja M; Radivoyevitch, Tomas T; Xicoy, Blanca B; Pellagatti, Andrea A; Haferlach, Claudia C; Boultwood, Jacqueline J; Kern, Wolfgang W; Visconte, Valeria V; Sekeres, Mikkael M; Barnard, John J; Haferlach, Torsten T; Solé, Francesc F; Maciejewski, Jaroslaw P JP
Publication Date: 2022-05-23

Variant appearance in text: TP53: 818G>A; Arg273His
PubMed Link: 35617825
Variant Present in the following documents:
  • mmc3.xlsx
View BVdb publication page



Synthetic lethality between TP53 and ENDOD1.

Nature Communications
Tang, Zizhi Z; Zeng, Ming M; Wang, Xiaojun X; Guo, Chang C; Yue, Peng P; Zhang, Xiaohu X; Lou, Huiqiang H; Chen, Jun J; Mu, Dezhi D; Kong, Daochun D; Carr, Antony M AM; Liu, Cong C
Publication Date: 2022-05-23

Variant appearance in text: TP53: R273H
PubMed Link: 35606358
Variant Present in the following documents:
  • Main text
  • 41467_2022_30311_MOESM1_ESM.pdf
  • 41467_2022_Article_30311.pdf
View BVdb publication page



p53 wild-type colorectal cancer cells that express a fetal gene signature are associated with metastasis and poor prognosis.

Nature Communications
Solé, Laura L; Lobo-Jarne, Teresa T; Álvarez-Villanueva, Daniel D; Alonso-Marañón, Josune J; Guillén, Yolanda Y; Guix, Marta M; Sangrador, Irene I; Rozalén, Catalina C; Vert, Anna A; Barbachano, Antonio A; Lop, Joan J; Salido, Marta M; Bellosillo, Beatriz B; García-Romero, Raquel R; Garrido, Marta M; González, Jessica J; Martínez-Iniesta, María M; López-Arribillaga, Erika E; Salazar, Ramón R; Montagut, Clara C; Torres, Ferrán F; Iglesias, Mar M; Celià-Terrassa, Toni T; Muñoz, Alberto A; Villanueva, Alberto A; Bigas, Anna A; Espinosa, Lluís L
Publication Date: 2022-05-23

Variant appearance in text: TP53: R273H
PubMed Link: 35606354
Variant Present in the following documents:
  • 41467_2022_30382_MOESM1_ESM.pdf
View BVdb publication page



N6 -methyladenosine-RNA methylation promotes expression of solute carrier family 7 member 11, an uptake transporter of cystine for lipid reactive oxygen species scavenger glutathione synthesis, leading to hepatoblastoma ferroptosis resistance.

Clinical And Translational Medicine
Hill, Ronald A RA; Liu, Yong-Yu YY
Publication Date: 2022-05

Variant appearance in text: p53: R273H
PubMed Link: 35604883
Variant Present in the following documents:
  • CTM2-12-e889.pdf
View BVdb publication page



Distinct landscapes of deleterious variants in DNA damage repair system in ethnic human populations.

Life Science Alliance
Qin, Zixin Z; Huang, Teng T; Guo, Maoni M; Wang, San Ming SM
Publication Date: 2022-09

Variant appearance in text: TP53: 818G>A; Arg273His; rs28934576
PubMed Link: 35595529
Variant Present in the following documents:
  • LSA-2021-01319_TableS1.xlsx
  • LSA-2021-01319_TableS3.xlsx
  • LSA-2021-01319_TableS4.xlsx
View BVdb publication page



Aberrantly Activated APOBEC3B Is Associated With Mutant p53-Driven Refractory/Relapsed Diffuse Large B-Cell Lymphoma.

Frontiers In Immunology
Zhang, Xuzhao X; Wu, Zhaoxing Z; Hao, Yuanyuan Y; Yu, Teng T; Li, Xian X; Liang, Yun Y; Li, Jinfan J; Huang, Liansheng L; Xu, Yang Y; Li, Xiuzhen X; Xu, Xiaohua X; Wang, Weiqin W; Xu, Genbo G; Zhang, Xiaohong X; Lv, Qinghua Q; Fang, Yongming Y; Xu, Rongzhen R; Qian, Wenbin W
Publication Date: 2022

Variant appearance in text: TP53: R273H
PubMed Link: 35592333
Variant Present in the following documents:
  • Main text
  • fimmu-13-888250.pdf
View BVdb publication page



Cedrus atlantica extract exerts antiproliferative effect on colorectal cancer through the induction of cell cycle arrest and apoptosis.

Food Science & Nutrition
Huang, Chih-Yuan CY; Chien, Ju-Huei JH; Chang, Kai-Fu KF; Hsiao, Chih-Yen CY; Huang, Ya-Chih YC; Chen, Yi-Ting YT; Hsu, Ming-Yi MY; Hsieh, Ming-Chang MC; Tsai, Nu-Man NM
Publication Date: 2022-05

Variant appearance in text: TP53: R273H
PubMed Link: 35592288
Variant Present in the following documents:
  • Main text
  • FSN3-10-1638.pdf
View BVdb publication page



Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients.

Nature Communications
Hassin, Ori O; Nataraj, Nishanth Belugali NB; Shreberk-Shaked, Michal M; Aylon, Yael Y; Yaeger, Rona R; Fontemaggi, Giulia G; Mukherjee, Saptaparna S; Maddalena, Martino M; Avioz, Adi A; Iancu, Ortal O; Mallel, Giuseppe G; Gershoni, Anat A; Grosheva, Inna I; Feldmesser, Ester E; Ben-Dor, Shifra S; Golani, Ofra O; Hendel, Ayal A; Blandino, Giovanni G; Kelsen, David D; Yarden, Yosef Y; Oren, Moshe M
Publication Date: 2022-05-19

Variant appearance in text: p53: R273H
PubMed Link: 35589715
Variant Present in the following documents:
  • Main text
  • 41467_2022_30481_MOESM2_ESM.pdf
  • 41467_2022_Article_30481.pdf
  • 41467_2022_30481_MOESM1_ESM.pdf
View BVdb publication page



BAP1 phosphorylation-mediated Sp1 stabilization plays a critical role in cathepsin K inhibition-induced C-terminal p53-dependent Bax upregulation.

Redox Biology
Seo, Seung Un SU; Woo, Seon Min SM; Lee, Seul Gi SG; Kim, Min Yeong MY; Lee, Hyun Shik HS; Choi, Yung Hyun YH; Kim, Sang Hyun SH; Chang, Young-Chae YC; Min, Kyoung-Jin KJ; Kwon, Taeg Kyu TK
Publication Date: 2022-05-13

Variant appearance in text: p53: R273H
PubMed Link: 35584569
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Regulatory RNAs, microRNA, long-non coding RNA and circular RNA roles in colorectal cancer stem cells.

World Journal Of Gastrointestinal Oncology
Chao, Hsiao-Mei HM; Wang, Teh-Wei TW; Chern, Edward E; Hsu, Shan-Hui SH
Publication Date: 2022-04-15

Variant appearance in text: p53: R273H
PubMed Link: 35582099
Variant Present in the following documents:
  • WJGO-14-748.pdf
View BVdb publication page



Characterization of acquired nutlin-3 resistant non-small cell lung cancer cells.

Cancer Drug Resistance (Alhambra, Calif.)
Deben, Christophe C; Boullosa, Laurie Freire LF; Domen, Andreas A; Wouters, An A; Cuypers, Bart B; Laukens, Kris K; Lardon, Filip F; Pauwels, Patrick P
Publication Date: 2021

Variant appearance in text: p53: R273H
PubMed Link: 35582010
Variant Present in the following documents:
  • cdr-4-233.pdf
View BVdb publication page



Homologous recombination deficiency in diverse cancer types and its correlation with platinum chemotherapy efficiency in ovarian cancer.

Bmc Cancer
Wen, Hao H; Feng, Zheng Z; Ma, Yutong Y; Liu, Rui R; Ou, Qiuxiang Q; Guo, Qinhao Q; Shen, Yi Y; Wu, Xue X; Shao, Yang Y; Bao, Hua H; Wu, Xiaohua X
Publication Date: 2022-05-16

Variant appearance in text: TP53: 818G>A; R273H
PubMed Link: 35578198
Variant Present in the following documents:
  • 12885_2022_9602_MOESM9_ESM.xlsx
View BVdb publication page



Liquid Biopsy in Squamous Cell Carcinoma of the Esophagus and of the Head and Neck.

Frontiers In Medicine
Iacob, Razvan R; Mandea, Matei M; Iacob, Speranta S; Pietrosanu, Catalina C; Paul, Doru D; Hainarosie, Razvan R; Gheorghe, Cristian C
Publication Date: 2022

Variant appearance in text: TP53: R273H
PubMed Link: 35572996
Variant Present in the following documents:
  • fmed-09-827297.pdf
View BVdb publication page



T Cell Defects: New Insights Into the Primary Resistance Factor to CD19/CD22 Cocktail CAR T-Cell Immunotherapy in Diffuse Large B-Cell Lymphoma.

Frontiers In Immunology
Wang, Jiachen J; Shen, Kefeng K; Mu, Wei W; Li, Weigang W; Zhang, Meilan M; Zhang, Wei W; Li, Zhe Z; Ge, Tong T; Zhu, Zhoujie Z; Zhang, Shangkun S; Chen, Caixia C; Xing, Shugang S; Zhu, Li L; Chen, Liting L; Wang, Na N; Huang, Liang L; Li, Dengju D; Xiao, Min M; Zhou, Jianfeng J
Publication Date: 2022

Variant appearance in text: TP53: 818G>A
PubMed Link: 35572515
Variant Present in the following documents:
  • Table_2.xlsx
  • fimmu-13-873789.pdf
View BVdb publication page



Immunohistochemical study of epidermal growth factor receptor, human epidermal growth factor receptor 2/neu, p53, and Ki67 in oral squamous cell carcinoma.

Journal Of Oral And Maxillofacial Pathology : Jomfp
Mohanapure, Neelam Sureshrao NS; Khandeparkar, Siddhi Gaurish Sinai SGS; Saragade, Pradnya B PB; Gogate, Bageshri P BP; Joshi, Avinash R AR; Mehta, Sameera Rajendra SR
Publication Date: 2022

Variant appearance in text: p53: R273H
PubMed Link: 35571320
Variant Present in the following documents:
  • JOMFP-26-127b.pdf
View BVdb publication page



Characterization of Temozolomide Resistance Using a Novel Acquired Resistance Model in Glioblastoma Cell Lines.

Cancers
Zhu, Yuan Y; Chen, Zhen Z; Kim, Su Na SN; Gan, Chao C; Ryl, Tatsiana T; Lesjak, Michaela Silvia MS; Rodemerk, Jan J; Zhong, Rong De R; Wrede, Karsten K; Dammann, Philipp P; Sure, Ulrich U
Publication Date: 2022-04-28

Variant appearance in text: p53: R273H
PubMed Link: 35565340
Variant Present in the following documents:
  • cancers-14-02211.pdf
View BVdb publication page



High-Throughput Profiling of Colorectal Cancer Liver Metastases Reveals Intra- and Inter-Patient Heterogeneity in the EGFR and WNT Pathways Associated with Clinical Outcome.

Cancers
Menck, Kerstin K; Wlochowitz, Darius D; Wachter, Astrid A; Conradi, Lena-Christin LC; Wolff, Alexander A; Scheel, Andreas H AH; Korf, Ulrike U; Wiemann, Stefan S; Schildhaus, Hans-Ulrich HU; Bohnenberger, Hanibal H; Wingender, Edgar E; Pukrop, Tobias T; Homayounfar, Kia K; Beißbarth, Tim T; Bleckmann, Annalen A
Publication Date: 2022-04-21

Variant appearance in text: TP53: Arg273His
PubMed Link: 35565214
Variant Present in the following documents:
  • cancers-14-02084.pdf
View BVdb publication page



The Role of E3 Ligase Pirh2 in Disease.

Cells
Daks, Alexandra A; Fedorova, Olga O; Parfenyev, Sergey S; Nevzorov, Ivan I; Shuvalov, Oleg O; Barlev, Nickolai A NA
Publication Date: 2022-04-30

Variant appearance in text: p53: R273H
PubMed Link: 35563824
Variant Present in the following documents:
  • cells-11-01515.pdf
View BVdb publication page



Plant Alkaloid Tetrandrine Is a Nuclear Receptor 4A1 Antagonist and Inhibits Panc-1 Cell Growth In Vitro and In Vivo.

International Journal Of Molecular Sciences
Lee, Hyo-Seon HS; Kim, Dae Hwan DH; Lee, In-Seon IS; Park, Ji-Hyun JH; Martin, Gregory G; Safe, Stephen S; Kim, Keuk-Jun KJ; Kim, Joung-Hee JH; Jang, Byung Ik BI; Lee, Syng-Ook SO
Publication Date: 2022-05-09

Variant appearance in text: p53: R273H
PubMed Link: 35563670
Variant Present in the following documents:
  • ijms-23-05280.pdf
View BVdb publication page



Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways.

Nature Communications
Zhang, Yiqun Y; Chen, Fengju F; Chandrashekar, Darshan S DS; Varambally, Sooryanarayana S; Creighton, Chad J CJ
Publication Date: 2022-05-13

Variant appearance in text: p53: R273H
PubMed Link: 35562349
Variant Present in the following documents:
  • 41467_2022_30342_MOESM4_ESM.xlsx
View BVdb publication page



Fundamental immune-oncogenicity trade-offs define driver mutation fitness.

Nature
Hoyos, David D; Zappasodi, Roberta R; Schulze, Isabell I; Sethna, Zachary Z; de Andrade, Kelvin César KC; Bajorin, Dean F DF; Bandlamundi, Chaitanya C; Callahan, Margaret K MK; Funt, Samuel A SA; Hadrup, Sine R SR; Holm, Jeppe S JS; Rosenberg, Jonathan E JE; Shah, Sohrab P SP; Vázquez-García, Ignacio I; Weigelt, Britta B; Wu, Michelle M; Zamarin, Dmitriy D; Campitelli, Laura F LF; Osborne, Edward J EJ; Klinger, Mark M; Robins, Harlan S HS; Khincha, Payal P PP; Savage, Sharon A SA; Balachandran, Vinod P VP; Wolchok, Jedd D JD; Hellmann, Matthew D MD; Merghoub, Taha T; Levine, Arnold J AJ; Łuksza, Marta M; Greenbaum, Benjamin D BD
Publication Date: 2022-05-11

Variant appearance in text: TP53: R273H
PubMed Link: 35545680
Variant Present in the following documents:
  • 41586_2022_Article_4696.pdf
  • 41586_2022_4696_MOESM1_ESM.pdf
View BVdb publication page



Mutual exclusivity of ESR1 and TP53 mutations in endocrine resistant metastatic breast cancer.

Npj Breast Cancer
Li, Zheqi Z; Spoelstra, Nicole S NS; Sikora, Matthew J MJ; Sams, Sharon B SB; Elias, Anthony A; Richer, Jennifer K JK; Lee, Adrian V AV; Oesterreich, Steffi S
Publication Date: 2022-05-10

Variant appearance in text: TP53: R273H
PubMed Link: 35538119
Variant Present in the following documents:
  • 41523_2022_426_MOESM1_ESM.pdf
View BVdb publication page



Comparative genomic analysis of esophageal squamous cell carcinoma and adenocarcinoma: New opportunities towards molecularly targeted therapy.

Acta Pharmaceutica Sinica. B
Zhang, Xu X; Wang, Yuxiang Y; Meng, Linghua L
Publication Date: 2022-03

Variant appearance in text: TP53: R273H
PubMed Link: 35530133
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Paclitaxel and cisplatin with or without cetuximab in metastatic esophageal squamous cell carcinoma: a randomized, multicenter phase II trial.

Innovation (Cambridge (Mass.))
Lu, Zhihao Z; Zhang, Yanqiao Y; Fan, Qingxia Q; Pan, Yueyin Y; Jiang, Da D; Lu, Ping P; Zhang, Jingdong J; Yuan, Xianglin X; Feng, Jifeng J; Yang, Shujun S; Yue, Wenbin W; Zhao, Lin L; Xu, Yunhua Y; Luo, Jinhua J; Shen, Lin L
Publication Date: 2022-05-10

Variant appearance in text: TP53: 818G>A; R273H
PubMed Link: 35509869
Variant Present in the following documents:
  • mmc2.xlsx
View BVdb publication page



Alterations in homologous recombination repair genes in prostate cancer brain metastases.

Nature Communications
Rodriguez-Calero, Antonio A; Gallon, John J; Akhoundova, Dilara D; Maletti, Sina S; Ferguson, Alison A; Cyrta, Joanna J; Amstutz, Ursula U; Garofoli, Andrea A; Paradiso, Viola V; Tomlins, Scott A SA; Hewer, Ekkehard E; Genitsch, Vera V; Fleischmann, Achim A; Vassella, Erik E; Rushing, Elisabeth J EJ; Grobholz, Rainer R; Fischer, Ingeborg I; Jochum, Wolfram W; Cathomas, Gieri G; Osunkoya, Adeboye O AO; Bubendorf, Lukas L; Moch, Holger H; Thalmann, George G; Ng, Charlotte K Y CKY; Gillessen, Silke S; Piscuoglio, Salvatore S; Rubin, Mark A MA
Publication Date: 2022-05-03

Variant appearance in text: TP53: Arg273His; rs28934576
PubMed Link: 35504881
Variant Present in the following documents:
  • 41467_2022_30003_MOESM5_ESM.xlsx
View BVdb publication page



Rare evolution of CSF3R-mutated chronic neutrophilic leukemia to t(4;12)(q12;p13) acute myeloid leukemia with SETBP1 mutation.

Leukemia Research Reports
Hirao, Maki M; Watanabe, Kentaro K; Tsukada, Yuiko Y; Kunieda, Hisako H; Osada, Makoto M; Yamazaki, Kohei K; Denda, Ryunosuke R; Okamoto, Shinichiro S; Kikuchi, Takahide T
Publication Date: 2022

Variant appearance in text: TP53: R273H
PubMed Link: 35497674
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Non-Hodgkin lymphoma mimicking acute leukemia: a report of six cases and review of the literature.

Journal Of Hematopathology
Dorfman, David M DM; Sadigh, Sam S
Publication Date: 2022-04-23

Variant appearance in text: TP53: 818G>A; R273H
PubMed Link: 35496359
Variant Present in the following documents:
  • 12308_2022_Article_493.pdf
View BVdb publication page



p53 and Zinc: A Malleable Relationship.

Frontiers In Molecular Biosciences
Ha, Jeung-Hoi JH; Prela, Orjola O; Carpizo, Darren R DR; Loh, Stewart N SN
Publication Date: 2022

Variant appearance in text: p53: R273H
PubMed Link: 35495631
Variant Present in the following documents:
  • fmolb-09-895887.pdf
View BVdb publication page



Journey of anthraquinones as anticancer agents - a systematic review of recent literature.

Rsc Advances
Malik, M Shaheer MS; Alsantali, Reem I RI; Jassas, Rabab S RS; Alsimaree, Abdulrahman A AA; Syed, Riyaz R; Alsharif, Meshari A MA; Kalpana, Kulkarni K; Morad, Moataz M; Althagafi, Ismail I II; Ahmed, Saleh A SA
Publication Date: 2021-11-04

Variant appearance in text: p53: R273H
PubMed Link: 35492773
Variant Present in the following documents:
  • RA-011-D1RA05686G.pdf
View BVdb publication page



Synergistic blocking of RAS downstream signaling and epigenetic pathway in KRAS mutant pancreatic cancer.

Aging
Zhang, Xiaofei X; Mao, Tiebo T; Xu, Haiyan H; Li, Shumin S; Yue, Ming M; Ma, Jingyu J; Yao, Jiayu J; Wang, Yongchao Y; Zhang, Xiao X; Ge, Weiyu W; Wang, Yanling Y; Shentu, Daiyuan D; Wang, Liwei L
Publication Date: 2022-04-25

Variant appearance in text: TP53: R273H
PubMed Link: 35468095
Variant Present in the following documents:
  • aging-14-204031.pdf
View BVdb publication page



Inhibitory Response to CK II Inhibitor Silmitasertib and CDKs Inhibitor Dinaciclib Is Related to Genetic Differences in Pancreatic Ductal Adenocarcinoma Cell Lines.

International Journal Of Molecular Sciences
Ma, Yixuan Y; Sender, Sina S; Sekora, Anett A; Kong, Weibo W; Bauer, Peter P; Ameziane, Najim N; Krake, Susann S; Radefeldt, Mandy M; Al-Ali, Ruslan R; Weiss, Frank Ulrich FU; Lerch, Markus M MM; Parveen, Alisha A; Zechner, Dietmar D; Junghanss, Christian C; Murua Escobar, Hugo H
Publication Date: 2022-04-16

Variant appearance in text: TP53: 818G>A
PubMed Link: 35457227
Variant Present in the following documents:
  • ijms-23-04409.pdf
View BVdb publication page



The Inhibitory Response to PI3K/AKT Pathway Inhibitors MK-2206 and Buparlisib Is Related to Genetic Differences in Pancreatic Ductal Adenocarcinoma Cell Lines.

International Journal Of Molecular Sciences
Ma, Yixuan Y; Sender, Sina S; Sekora, Anett A; Kong, Weibo W; Bauer, Peter P; Ameziane, Najim N; Al-Ali, Ruslan R; Krake, Susann S; Radefeldt, Mandy M; Weiss, Frank Ulrich FU; Lerch, Markus M MM; Parveen, Alisha A; Zechner, Dietmar D; Junghanss, Christian C; Murua Escobar, Hugo H
Publication Date: 2022-04-13

Variant appearance in text: TP53: 818G>A
PubMed Link: 35457111
Variant Present in the following documents:
  • ijms-23-04295.pdf
View BVdb publication page



An Unanticipated Modulation of Cyclin-Dependent Kinase Inhibitors: The Role of Long Non-Coding RNAs.

Cells
Bencivenga, Debora D; Stampone, Emanuela E; Vastante, Angela A; Barahmeh, Myassar M; Della Ragione, Fulvio F; Borriello, Adriana A
Publication Date: 2022-04-14

Variant appearance in text: p53: R273H
PubMed Link: 35456025
Variant Present in the following documents:
  • cells-11-01346.pdf
View BVdb publication page



Mixed Neuroendocrine Non-Neuroendocrine Neoplasms of the Gastrointestinal Tract: A Case Series.

Healthcare (Basel, Switzerland)
Guerrera, Luigi Pio LP; Suarato, Gabriella G; Napolitano, Rossella R; Perrone, Alessandra A; Caputo, Vincenza V; Ventriglia, Anna A; Martini, Giulia G; Della Corte, Carminia Maria CM; Orditura, Michele M; Martinelli, Erika E; Ciardiello, Fortunato F; Montella, Marco M; Franco, Renato R; Troiani, Teresa T; Napolitano, Stefania S
Publication Date: 2022-04-11

Variant appearance in text: TP53: R273H
PubMed Link: 35455885
Variant Present in the following documents:
  • healthcare-10-00708.pdf
View BVdb publication page



Preclinical Efficacy and Toxicity Analysis of the Pan-Histone Deacetylase Inhibitor Gossypol for the Therapy of Colorectal Cancer or Hepatocellular Carcinoma.

Pharmaceuticals (Basel, Switzerland)
Mayer, Mascha M; Berger, Alexander A; Leischner, Christian C; Renner, Olga O; Burkard, Markus M; Böcker, Alexander A; Noor, Seema S; Weiland, Timo T; Weiss, Thomas S TS; Busch, Christian C; Lauer, Ulrich M UM; Bischoff, Stephan C SC; Venturelli, Sascha S
Publication Date: 2022-04-01

Variant appearance in text: p53: R273H
PubMed Link: 35455435
Variant Present in the following documents:
  • pharmaceuticals-15-00438.pdf
View BVdb publication page



Single-EV analysis (sEVA) of mutated proteins allows detection of stage 1 pancreatic cancer.

Science Advances
Ferguson, Scott S; Yang, Katherine S KS; Zelga, Piotr P; Liss, Andrew S AS; Carlson, Jonathan C T JCT; Del Castillo, Carlos Fernandez CF; Weissleder, Ralph R
Publication Date: 2022-04-22

Variant appearance in text: p53: R273H
PubMed Link: 35452280
Variant Present in the following documents:
  • sciadv.abm3453_sm.pdf
View BVdb publication page



Integrated profiling of human pancreatic cancer organoids reveals chromatin accessibility features associated with drug sensitivity.

Nature Communications
Shi, Xiaohan X; Li, Yunguang Y; Yuan, Qiuyue Q; Tang, Shijie S; Guo, Shiwei S; Zhang, Yehan Y; He, Juan J; Zhang, Xiaoyu X; Han, Ming M; Liu, Zhuang Z; Zhu, Yiqin Y; Gao, Suizhi S; Wang, Huan H; Xu, Xiongfei X; Zheng, Kailian K; Jing, Wei W; Chen, Luonan L; Wang, Yong Y; Jin, Gang G; Gao, Dong D
Publication Date: 2022-04-21

Variant appearance in text: TP53: R273H
PubMed Link: 35449156
Variant Present in the following documents:
  • 41467_2022_29857_MOESM5_ESM.xlsx
View BVdb publication page



5-Hydroxymethylcytosine (5hmC) at or near cancer mutation hot spots as potential targets for early cancer detection.

Bmc Research Notes
Lu, Michael J MJ; Lu, Yabin Y
Publication Date: 2022-04-21

Variant appearance in text: TP53: 818G>A; R273H
PubMed Link: 35449110
Variant Present in the following documents:
  • 13104_2022_Article_6028.pdf
View BVdb publication page



Development and evaluation of ActSeq: A targeted next-generation sequencing panel for clinical oncology use.

Plos One
Shi, Zonggao Z; Lopez, Jacqueline J; Kalliney, William W; Sutton, Bobbie B; Simpson, Joyce J; Maggert, Kevin K; Liu, Sheng S; Wan, Jun J; Stack, M Sharon MS
Publication Date: 2022

Variant appearance in text: TP53: R273H
PubMed Link: 35446881
Variant Present in the following documents:
  • pone.0266914.pdf
View BVdb publication page



Size-tuneable and immunocompatible polymer nanocarriers for drug delivery in pancreatic cancer.

Nanoscale
Popov, Andrea Bistrović AB; Melle, Francesca F; Linnane, Emily E; González-López, Cristina C; Ahmed, Ishtiaq I; Parshad, Badri B; Franck, Christoph O CO; Rahmoune, Hassan H; Richards, Frances M FM; Muñoz-Espín, Daniel D; Jodrell, Duncan I DI; Fairen-Jimenez, David D; Fruk, Ljiljana L
Publication Date: 2022-04-19

Variant appearance in text: TP53: R273H
PubMed Link: 35438701
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic Alterations and Microenvironment that Drive Malignant Progression of Colorectal Cancer: Lessons from Mouse and Organoid Models.

Journal Of Cancer Prevention
Nakayama, Mizuho M; Wang, Dong D; Kok, Sau Yee SY; Oshima, Hiroko H; Oshima, Masanobu M
Publication Date: 2022-03-30

Variant appearance in text: p53: R273H
PubMed Link: 35419304
Variant Present in the following documents:
  • jcp-27-1-1.pdf
View BVdb publication page



Butyrate supplementation regulates expression of chromosome segregation 1‑like protein to reverse the genetic distortion caused by p53 mutations in colorectal cancer.

International Journal Of Oncology
Chang, Chun-Chao CC; Kao, Wei-Yu WY; Liu, Chih-Yi CY; Su, Hui-Hsien HH; Kan, Yu-An YA; Lin, Pao-Ying PY; Ku, Wei-Chi WC; Chang, Kang-Wei KW; Yang, Ruey-Neng RN; Huang, Chi-Jung CJ
Publication Date: 2022-06

Variant appearance in text: p53: R273H
PubMed Link: 35417036
Variant Present in the following documents:
  • ijo-60-06-05354.pdf
View BVdb publication page



PIM1 genetic alterations associated with distinct molecular profiles, phenotypes and drug responses in diffuse large B-cell lymphoma.

Clinical And Translational Medicine
Zhang, Huilai H; Lu, Yaxiao Y; Zhang, Tingting T; Guan, Qingpei Q; Wang, Xiaoxuan X; Guo, Yixian Y; Li, Lanfang L; Qiu, Lihua L; Qian, Zhengzi Z; Zhou, Shiyong S; Gong, Wenchen W; Meng, Bin B; Ren, Xiubao X; Wang, Xianhuo X
Publication Date: 2022-04

Variant appearance in text: TP53: R273H
PubMed Link: 35415904
Variant Present in the following documents:
  • CTM2-12-e808-s003.xlsx
View BVdb publication page



Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune escape through PHLPP2/AKT/PD-L1 pathway.

International Journal Of Biological Sciences
Liu, Nannan N; Jiang, Xinxiu X; Guo, Leiming L; Zhang, Chuchu C; Jiang, Meimei M; Sun, Zhuoran Z; Zhang, Yizheng Y; Mi, Wunan W; Li, Jiehan J; Fu, Yang Y; Wang, Feng F; Zhang, Lingling L; Zhang, Yingjie Y
Publication Date: 2022

Variant appearance in text: p53: R273H
PubMed Link: 35414774
Variant Present in the following documents:
  • ijbsv18p2419s1.pdf
  • ijbsv18p2419.pdf
View BVdb publication page



BRCA1/2 Serves as a Biomarker for Poor Prognosis in Breast Carcinoma.

International Journal Of Molecular Sciences
Jin, Tong Yi TY; Park, Kyoung Sik KS; Nam, Sang Eun SE; Yoo, Young Bum YB; Park, Won Seo WS; Yun, Ik Jin IJ
Publication Date: 2022-03-29

Variant appearance in text: p53: R273H
PubMed Link: 35409110
Variant Present in the following documents:
  • ijms-23-03754.pdf
View BVdb publication page



The Regulatory Functions and the Mechanisms of Long Non-Coding RNAs in Cervical Cancer.

Cells
Yang, Qiwei Q; Al-Hendy, Ayman A
Publication Date: 2022-03-29

Variant appearance in text: p53: R273H
PubMed Link: 35406713
Variant Present in the following documents:
  • cells-11-01149.pdf
View BVdb publication page



Inhibiting the Priming for Cancer in Li-Fraumeni Syndrome.

Cancers
Pantziarka, Pan P; Blagden, Sarah S
Publication Date: 2022-03-23

Variant appearance in text: TP53: R273H
PubMed Link: 35406393
Variant Present in the following documents:
  • cancers-14-01621.pdf
View BVdb publication page



Comprehensive analysis of genetic factors predicting overall survival in Myelodysplastic syndromes.

Scientific Reports
Maurya, Nehakumari N; Mohanty, Purvi P; Dhangar, Somprakash S; Panchal, Purvi P; Jijina, Farah F; Mathan, S Leo Prince SLP; Shanmukhaiah, Chandrakala C; Madkaikar, Manisha M; Vundinti, Babu Rao BR
Publication Date: 2022-04-08

Variant appearance in text: TP53: 818G>A; Arg273His
PubMed Link: 35396491
Variant Present in the following documents:
  • 41598_2022_9864_MOESM9_ESM.xlsx
View BVdb publication page



Phase 1b study of berzosertib and cisplatin in patients with advanced triple-negative breast cancer.

Npj Breast Cancer
Telli, Melinda L ML; Tolaney, Sara M SM; Shapiro, Geoffrey I GI; Middleton, Mark M; Lord, Simon R SR; Arkenau, Hendrik Tobias HT; Tutt, Andrew A; Abramson, Vandana V; Dean, Emma E; Haddad, Tufia C TC; Wesolowski, Robert R; Ferrer-Playan, Jordi J; Goddemeier, Thomas T; Grombacher, Thomas T; Dong, Jennifer J; Fleuranceau-Morel, Patricia P; Diaz-Padilla, Ivan I; Plummer, Ruth R
Publication Date: 2022-04-07

Variant appearance in text: TP53: R273H
PubMed Link: 35393425
Variant Present in the following documents:
  • 41523_2022_406_MOESM1_ESM.pdf
View BVdb publication page



Deciphering the Increased Prevalence of TP53 Mutations in Metastatic Prostate Cancer.

Cancer Informatics
Zhang, Wensheng W; Dong, Yan Y; Sartor, Oliver O; Zhang, Kun K
Publication Date: 2022

Variant appearance in text: TP53: 818G>A
PubMed Link: 35392296
Variant Present in the following documents:
  • 10.1177_11769351221087046.pdf
View BVdb publication page



Comprehensive Analysis of the Carcinogenic Process, Tumor Microenvironment, and Drug Response in HPV-Positive Cancers.

Frontiers In Oncology
Yu, Xiaorong X; Xu, Jiankai J; Xu, Dahua D; Bi, Xiaoman X; Wang, Hong H; Lu, Yanda Y; Cao, Meng M; Wang, Wenxiang W; Xu, Zhizhou Z; Zheng, Dehua D; Chen, Liyang L; Zhang, Xiaodian X; Zheng, Shaojiang S; Li, Kongning K
Publication Date: 2022

Variant appearance in text: p53: R273H
PubMed Link: 35392231
Variant Present in the following documents:
  • fonc-12-842060.pdf
View BVdb publication page



Genomic clonal evolution correlated with phenotype and prognosis in gastric cancer.

Clinical And Translational Medicine
Ge, Jie J; Li, Xuan X; Deng, Zhenghao Z; Gao, Xuan X; Liu, Yaoyao Y; Xiong, Xingui X; Zhao, Xianhui X; Peng, Huan H; Yi, Xin X; Xia, Xuefeng X; Chen, Zihua Z; Li, Lifeng L; Zhou, Haiyan H; Liu, Heli H
Publication Date: 2022-04

Variant appearance in text: TP53: 818G>A; R273H
PubMed Link: 35384329
Variant Present in the following documents:
  • CTM2-12-e799-s006.xlsx
View BVdb publication page



Downregulation of KRAB zinc finger proteins in 5-fluorouracil resistant colorectal cancer cells.

Bmc Cancer
Chauvin, Anaïs A; Bergeron, Danny D; Vencic, Jean J; Lévesque, Dominique D; Paquette, Benoit B; Scott, Michelle S MS; Boisvert, François-Michel FM
Publication Date: 2022-04-04

Variant appearance in text: TP53: R273H
PubMed Link: 35379199
Variant Present in the following documents:
  • 12885_2022_Article_9417.pdf
View BVdb publication page



A Custom DNA-Based NGS Panel for the Molecular Characterization of Patients With Diffuse Gliomas: Diagnostic and Therapeutic Applications.

Frontiers In Oncology
Tirrò, Elena E; Massimino, Michele M; Broggi, Giuseppe G; Romano, Chiara C; Minasi, Simone S; Gianno, Francesca F; Antonelli, Manila M; Motta, Gianmarco G; Certo, Francesco F; Altieri, Roberto R; Manzella, Livia L; Caltabiano, Rosario R; Barbagallo, Giuseppe Maria Vincenzo GMV; Buttarelli, Francesca Romana FR; Magro, Gaetano G; Giangaspero, Felice F; Vigneri, Paolo P
Publication Date: 2022

Variant appearance in text: TP53: Arg273His
PubMed Link: 35372034
Variant Present in the following documents:
  • fonc-12-861078.pdf
View BVdb publication page



TP53 R273C Mutation Is Associated With Poor Prognosis in LGG Patients.

Frontiers In Genetics
Zhang, Jian J; Liu, Minglu M; Fang, Yujie Y; Li, Jinlong J; Chen, Yin Y; Jiao, Shunchang S
Publication Date: 2022

Variant appearance in text: TP53: R273H
PubMed Link: 35368662
Variant Present in the following documents:
  • fgene-13-720651.pdf
View BVdb publication page



Mutant p53: it's not all one and the same.

Cell Death And Differentiation
Kennedy, Margaret C MC; Lowe, Scott W SW
Publication Date: 2022-03-31

Variant appearance in text: p53: R273H
PubMed Link: 35361963
Variant Present in the following documents:
  • 41418_2022_Article_989.pdf
View BVdb publication page



Clinical utility of comprehensive genomic profiling in Japan: Result of PROFILE-F study.

Plos One
Aoyagi, Yasuko Y; Kano, Yoshihito Y; Tohyama, Kohki K; Matsudera, Shotaro S; Kumaki, Yuichi Y; Takahashi, Kenta K; Mitsumura, Takahiro T; Harada, Yohei Y; Sato, Akemi A; Nakamura, Hideaki H; Sueoka, Eisaburo E; Aragane, Naoko N; Kimura, Koichiro K; Onishi, Iichiro I; Takemoto, Akira A; Akahoshi, Keiichi K; Ono, Hiroaki H; Ishikawa, Toshiaki T; Tokunaga, Masanori M; Nakagawa, Tsuyoshi T; Oshima, Noriko N; Nakamura, Reiko R; Takagi, Masatoshi M; Asakage, Takahiro T; Uetake, Hiroyuki H; Tanabe, Minoru M; Miyake, Satoshi S; Kinugasa, Yusuke Y; Ikeda, Sadakatsu S
Publication Date: 2022

Variant appearance in text: TP53: R273H
PubMed Link: 35358259
Variant Present in the following documents:
  • pone.0266112.s001.xlsx
View BVdb publication page



Sensitivity of VHL mutant kidney cancers to HIF2 inhibitors does not require an intact p53 pathway.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Stransky, Laura A LA; Vigeant, Sean M SM; Huang, Bofu B; West, Destiny D; Denize, Thomas T; Walton, Emily E; Signoretti, Sabina S; Kaelin, William G WG
Publication Date: 2022-04-05

Variant appearance in text: TP53: R273H
PubMed Link: 35357972
Variant Present in the following documents:
  • pnas.2120403119.sapp.pdf
  • pnas.202120403.pdf
View BVdb publication page



Suppressive effect of α-mangostin for cancer stem cells in colorectal cancer via the Notch pathway.

Bmc Cancer
Jo, Min Kyoung MK; Moon, Chang Mo CM; Kim, Eun Ju EJ; Kwon, Ji-Hee JH; Fei, Xiang X; Kim, Seong-Eun SE; Jung, Sung-Ae SA; Kim, Minsuk M; Mun, Yeung-Chul YC; Ahn, Young-Ho YH; Seo, Seung-Yong SY; Kim, Tae Il TI
Publication Date: 2022-03-29

Variant appearance in text: TP53: R273H
PubMed Link: 35351071
Variant Present in the following documents:
  • 12885_2022_Article_9414.pdf
View BVdb publication page



Single-cell transcriptomic analysis suggests two molecularly subtypes of intrahepatic cholangiocarcinoma.

Nature Communications
Song, Guohe G; Shi, Yang Y; Meng, Lu L; Ma, Jiaqiang J; Huang, Siyuan S; Zhang, Juan J; Wu, Yingcheng Y; Li, Jiaxin J; Lin, Youpei Y; Yang, Shuaixi S; Rao, Dongning D; Cheng, Yifei Y; Lin, Jian J; Ji, Shuyi S; Liu, Yuming Y; Jiang, Shan S; Wang, Xiaoliang X; Zhang, Shu S; Ke, Aiwu A; Wang, Xiaoying X; Cao, Ya Y; Ji, Yuan Y; Zhou, Jian J; Fan, Jia J; Zhang, Xiaoming X; Xi, Ruibin R; Gao, Qiang Q
Publication Date: 2022-03-28

Variant appearance in text: TP53: 818G>A; R273H
PubMed Link: 35347134
Variant Present in the following documents:
  • 41467_2022_29164_MOESM13_ESM.xlsx
View BVdb publication page



Inhibition of Ceramide Glycosylation Enhances Cisplatin Sensitivity in Cholangiocarcinoma by Limiting the Activation of the ERK Signaling Pathway.

Life (Basel, Switzerland)
Chueakwon, Piyasiri P; Jatooratthawichot, Peeranat P; Talabnin, Krajang K; Ketudat Cairns, James R JR; Talabnin, Chutima C
Publication Date: 2022-02-28

Variant appearance in text: p53: R273H
PubMed Link: 35330102
Variant Present in the following documents:
  • life-12-00351.pdf
View BVdb publication page



p53 Immunohistochemistry and Mutation Types Mismatching in High-Grade Serous Ovarian Cancer.

Diagnostics (Basel, Switzerland)
Park, Eunhyang E; Han, Hyunho H; Choi, Sung-Eun SE; Park, Hyunjin H; Woo, Ha-Young HY; Jang, Mi M; Shim, Hyo-Sup HS; Hwang, Sohyun S; Kang, Haeyoun H; Cho, Nam-Hoon NH
Publication Date: 2022-02-24

Variant appearance in text: p53: R273H
PubMed Link: 35328131
Variant Present in the following documents:
  • diagnostics-12-00579.pdf
View BVdb publication page



Targeting Myc-driven stress vulnerability in mutant KRAS colorectal cancer.

Molecular Biomedicine
Ruan, Hang H; Leibowitz, Brian J BJ; Peng, Yingpeng Y; Shen, Lin L; Chen, Lujia L; Kuang, Charlie C; Schoen, Robert E RE; Lu, Xinghua X; Zhang, Lin L; Yu, Jian J
Publication Date: 2022-03-21

Variant appearance in text: TP53: R273H
PubMed Link: 35307764
Variant Present in the following documents:
  • 43556_2022_70_MOESM1_ESM.pdf
View BVdb publication page



Response prediction and risk stratification of patients with rectal cancer after neoadjuvant therapy through an analysis of circulating tumour DNA.

Ebiomedicine
Liu, Wenyang W; Li, Yifei Y; Tang, Yuan Y; Song, Qianqian Q; Wang, Jingjing J; Li, Ning N; Chen, Silin S; Shi, Jinming J; Wang, Shulian S; Li, Yexiong Y; Jiao, Yuchen Y; Zeng, Yixin Y; Jin, Jing J
Publication Date: 2022-03-17

Variant appearance in text: TP53: 818G>A
PubMed Link: 35306340
Variant Present in the following documents:
  • mmc3.xlsx
View BVdb publication page



Zebrafish imaging reveals TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesis.

Nature Communications
Haraoka, Yukinari Y; Akieda, Yuki Y; Nagai, Yuri Y; Mogi, Chihiro C; Ishitani, Tohru T
Publication Date: 2022-03-18

Variant appearance in text: TP53: R273H
PubMed Link: 35304872
Variant Present in the following documents:
  • 41467_2022_29061_MOESM1_ESM.pdf
  • 41467_2022_29061_MOESM2_ESM.pdf
View BVdb publication page



Establishment and characterization of a novel highly malignant lung cancer cell line ZX2021H derived from a metastatic lymph node lesion.

Thoracic Cancer
Zu, Lingling L; Li, Xuebing X; He, Jinling J; Zhou, Ning N; Meng, Fanrong F; Li, Xiaozhou X; Xu, Song S; Zhang, Lei L
Publication Date: 2022-03-16

Variant appearance in text: TP53: R273H
PubMed Link: 35297208
Variant Present in the following documents:
  • TCA-13-1199.pdf
View BVdb publication page



Perioperative Circulating Tumor DNA Enables Identification of Patients with Poor Prognosis in Upper Tract Urothelial Carcinoma.

Cancer Science
Nakano, Kosuke K; Koh, Yoko Y; Yamamichi, Gaku G; Yumiba, Satoru S; Tomiyama, Eisuke E; Matsushita, Makoto M; Hayashi, Yujiro Y; Wang, Cong C; Ishizuya, Yu Y; Yamamoto, Yoshiyuki Y; Kato, Taigo T; Hatano, Koji K; Kawashima, Atsunari A; Ujike, Takeshi T; Fujita, Kazutoshi K; Kiyotani, Kazuma K; Katayama, Kotoe K; Yamaguchi, Rui R; Imoto, Seiya S; Imamura, Ryoichi R; Nonomura, Norio N; Uemura, Motohide M
Publication Date: 2022-03-16

Variant appearance in text: TP53: R273H
PubMed Link: 35293110
Variant Present in the following documents:
  • CAS-113-1830-s004.xlsx
View BVdb publication page



Co-Expression and Combined Prognostic Value of CSPG4 and PDL1 in TP53-Aberrant Triple-Negative Breast Cancer.

Frontiers In Oncology
Hu, Zhe-Yu ZY; Zheng, Chanjuan C; Yang, Jianbo J; Ding, Siyu S; Tian, Can C; Xie, Ning N; Xue, Lian L; Wu, Muyao M; Fu, Shujun S; Rao, Zhouzhou Z; Price, Matthew A MA; McCarthy, James B JB; Ouyang, Quchang Q; Lin, Jizhen J; Deng, Xiyun X
Publication Date: 2022

Variant appearance in text: TP53: R273H
PubMed Link: 35280756
Variant Present in the following documents:
  • fonc-12-804466.pdf
View BVdb publication page



Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications
Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L
Publication Date: 2022-03-10

Variant appearance in text: TP53: 818G>A; R273H
PubMed Link: 35273153
Variant Present in the following documents:
  • 41467_2022_28840_MOESM7_ESM.xlsx
View BVdb publication page



Detection of germline variants in Brazilian breast cancer patients using multigene panel testing.

Scientific Reports
Guindalini, Rodrigo Santa Cruz RSC; Viana, Danilo Vilela DV; Kitajima, João Paulo Fumio Whitaker JPFW; Rocha, Vinícius Marques VM; López, Rossana Verónica Mendoza RVM; Zheng, Yonglan Y; Freitas, Érika É; Monteiro, Fabiola Paoli Mendes FPM; Valim, André A; Schlesinger, David D; Kok, Fernando F; Olopade, Olufunmilayo I OI; Folgueira, Maria Aparecida Azevedo Koike MAAK
Publication Date: 2022-03-09

Variant appearance in text: TP53: 818G>A; Arg273His
PubMed Link: 35264596
Variant Present in the following documents:
  • 41598_2022_Article_7383.pdf
  • 41598_2022_7383_MOESM2_ESM.xlsx
View BVdb publication page



Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog.

Cell Death & Disease
Zhang, Qiang Q; Balourdas, Dimitrios-Ilias DI; Baron, Bruno B; Senitzki, Alon A; Haran, Tali E TE; Wiman, Klas G KG; Soussi, Thierry T; Joerger, Andreas C AC
Publication Date: 2022-03-07

Variant appearance in text: p53: R273H
PubMed Link: 35256607
Variant Present in the following documents:
  • 41419_2022_4653_MOESM1_ESM.pdf
  • 41419_2022_Article_4653.pdf
View BVdb publication page



Landscape of TP53 Alterations in Chronic Lymphocytic Leukemia via Data Mining Mutation Databases.

Frontiers In Oncology
Soussi, Thierry T; Baliakas, Panagiotis P
Publication Date: 2022

Variant appearance in text: TP53: Arg273His
PubMed Link: 35251978
Variant Present in the following documents:
  • fonc-12-808886.pdf
View BVdb publication page



A distinctive requirement for p53 in the genome protective Topoisomerase 2a-dependent G2 arrest in hTERT positive cancer cells.

Cancer Research
Lockwood, Nicola N; Martini, Silvia S; López-Pardo, Ainara A; Deiss, Katharina K; Segeren, Hendrika A HA; Semple, Robert K RK; Collins, Ian I; Repana, Dimitra D; Cobbaut, Mathias M; Soliman, Tanya N TN; Ciccarelli, Francesca F; Parker, Peter J PJ
Publication Date: 2022-03-01

Variant appearance in text: TP53: R273H
PubMed Link: 35247890
Variant Present in the following documents:
  • EMS144799-supplement-Supplementary_Figures_and_Tables.pdf
  • EMS144799.pdf
View BVdb publication page



In PD-1+ human colon cancer cells NIVOLUMAB promotes survival and could protect tumor cells from conventional therapies.

Journal For Immunotherapy Of Cancer
Ieranò, Caterina C; Righelli, Dario D; D'Alterio, Crescenzo C; Napolitano, Maria M; Portella, Luigi L; Rea, Giuseppina G; Auletta, Federica F; Santagata, Sara S; Trotta, Anna Maria AM; Guardascione, Giuseppe G; Liotti, Federica F; Prevete, Nella N; Maiolino, Piera P; Luciano, Antonio A; Barbieri, Antonio A; Di Mauro, Annabella A; Roma, Cristin C; Esposito Abate, Riziero R; Tatangelo, Fabiana F; Pacelli, Roberto R; Normanno, Nicola N; Melillo, Rosa Marina RM; Scala, Stefania S
Publication Date: 2022-03

Variant appearance in text: TP53: R273H
PubMed Link: 35246475
Variant Present in the following documents:
  • jitc-2021-004032supp001.pdf
View BVdb publication page



miR-30a targets STOX2 to increase cell proliferation and metastasis in hydatidiform moles via ERK, AKT, and P38 signaling pathways.

Cancer Cell International
Guo, Zhenzhen Z; Zhu, Chenyu C; Wang, Youhui Y; Li, Zhen Z; Wang, Lu L; Fan, Jianhui J; Xu, Yuefei Y; Zou, Na N; Kong, Ying Y; Li, Dong D; Sui, Linlin L
Publication Date: 2022-03-04

Variant appearance in text: p53: R273H
PubMed Link: 35246136
Variant Present in the following documents:
  • 12935_2022_Article_2503.pdf
View BVdb publication page



Li-Fraumeni syndrome in Tunisian carriers with different and rare tumor phenotype: genotype-phenotype correlation.

Bmc Medical Genomics
Sassi, Hela H; Meddeb, Rym R; Cherif, Mohamed Aziz MA; Nasr, Chiraz C; Riahi, Aouatef A; Hannachi, Samia S; Belguith, Neila N; M'rad, Ridha R
Publication Date: 2022-03-04

Variant appearance in text: TP53: R273H
PubMed Link: 35246108
Variant Present in the following documents:
  • 12920_2022_Article_1189.pdf
View BVdb publication page



Rapid recruitment of p53 to DNA damage sites directs DNA repair choice and integrity.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Wang, Yu-Hsiu YH; Ho, Teresa L F TLF; Hariharan, Anushya A; Goh, Hui Chin HC; Wong, Yao Liang YL; Verkaik, Nicole S NS; Lee, May Yin MY; Tam, Wai Leong WL; van Gent, Dik C DC; Venkitaraman, Ashok R AR; Sheetz, Michael P MP; Lane, David P DP
Publication Date: 2022-03-08

Variant appearance in text: p53: R273H
PubMed Link: 35235448
Variant Present in the following documents:
  • pnas.202113233.pdf
View BVdb publication page



The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer
Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J
Publication Date: 2022-02

Variant appearance in text: TP53: Arg273His
PubMed Link: 35221333
Variant Present in the following documents:
  • 43018_2022_332_MOESM3_ESM.xlsx
View BVdb publication page