TP53 c.818G>A ;(p.R273H)

Variant ID: 17-7577120-C-T

NM_000546.5(TP53):c.818G>A;(p.R273H)

This variant was identified in 2287 publications

View GRCh38 version.




Publications:


Non-BRCA1/BRCA2 high-risk familial breast cancers are not associated with a high prevalence of BRCAness.

Breast Cancer Research : Bcr
Andersen, Lars V B LVB; Larsen, Martin J MJ; Davies, Helen H; Degasperi, Andrea A; Nielsen, Henriette Roed HR; Jensen, Louise A LA; Kroeldrup, Lone L; Gerdes, Anne-Marie AM; Lænkholm, Anne-Vibeke AV; Kruse, Torben A TA; Nik-Zainal, Serena S; Thomassen, Mads M
Publication Date: 2023-06-14

Variant appearance in text: TP53: 818G>A; R273H
PubMed Link: 37316882
Variant Present in the following documents:
  • 13058_2023_1655_MOESM9_ESM.xlsx, sheet 1
View BVdb publication page



Phase 1b trial of anti-EGFR antibody JMT101 and Osimertinib in EGFR exon 20 insertion-positive non-small-cell lung cancer.

Nature Communications
Zhao, Shen S; Zhuang, Wu W; Han, Baohui B; Song, Zhengbo Z; Guo, Wei W; Luo, Feng F; Wu, Lin L; Hu, Yi Y; Wang, Huijuan H; Dong, Xiaorong X; Jiang, Da D; Wang, Mingxia M; Miao, Liyun L; Wang, Qian Q; Zhang, Junping J; Fu, Zhenming Z; Huang, Yihua Y; Xu, Chunwei C; Hu, Longyu L; Li, Lei L; Hu, Rong R; Yang, Yang Y; Li, Mengke M; Yang, Xiugao X; Zhang, Li L; Huang, Yan Y; Fang, Wenfeng W
Publication Date: 2023-06-12

Variant appearance in text: TP53: 818G>A; R273H
PubMed Link: 37308490
Variant Present in the following documents:
  • 41467_2023_39139_MOESM4_ESM.xlsx, sheet 3
View BVdb publication page



Targeting protein glycosylation to regulate inflammation in the respiratory tract: novel diagnostic and therapeutic candidates for chronic respiratory diseases.

Frontiers In Immunology
Xie, Xiaofeng X; Kong, Siyuan S; Cao, Weiqian W
Publication Date: 2023

Variant appearance in text: p53: R273h
PubMed Link: 37256139
Variant Present in the following documents:
  • Main text
  • fimmu-14-1168023.pdf
View BVdb publication page



ATF2 loss promotes 5-FU resistance in colon cancer cells via activation of the ATR-Chk1 damage response pathway.

Bmc Cancer
Yang, Hao H; Huebner, Kerstin K; Hampel, Chuanpit C; Erlenbach-Wuensch, Katharina K; Selvamani, Selva Babu SB; Shukla, Vikas V; Geppert, Carol I CI; Hartmann, Arndt A; Mahadevan, Vijayalakshmi V; Schneider-Stock, Regine R
Publication Date: 2023-05-27

Variant appearance in text: p53: R273H
PubMed Link: 37237279
Variant Present in the following documents:
  • Main text
  • 12885_2023_Article_10940.pdf
View BVdb publication page



Case Report: Lung adenocarcinoma associated with germline ERCC2 frameshift mutation.

Frontiers In Oncology
Liu, Lili L; Cui, Jia J; Liu, Siye S; Pan, Evenki E; Sun, Limin L
Publication Date: 2023

Variant appearance in text: TP53: R273H
PubMed Link: 37223679
Variant Present in the following documents:
  • Main text
  • fonc-13-1177942.pdf
View BVdb publication page



Histone Demethylase Modulation: Epigenetic Strategy to Combat Cancer Progression.

Epigenomes
Srivastava, Rashmi R; Singh, Rubi R; Jauhari, Shaurya S; Lodhi, Niraj N; Srivastava, Rakesh R
Publication Date: 2023-05-17

Variant appearance in text: p53: R273H
PubMed Link: 37218871
Variant Present in the following documents:
  • epigenomes-07-00010.pdf
View BVdb publication page



TP53 Alterations in Myelodysplastic Syndromes and Acute Myeloid Leukemia.

Biomedicines
Rahmé, Ramy R; Braun, Thorsten T; Manfredi, James J JJ; Fenaux, Pierre P
Publication Date: 2023-04-11

Variant appearance in text: p53: R273H
PubMed Link: 37189770
Variant Present in the following documents:
  • Main text
  • biomedicines-11-01152.pdf
View BVdb publication page



Treatment and Response Evaluation Challenges in a Pregnant Woman With B-Cell Lymphoblastic Leukemia and Li-Fraumeni Syndrome.

Journal Of Hematology
Erikstein, Bjarte Skoe BS; Ahmed, Aymen Bushra AB; Forthun, Rakel Brendsdal RB; Leh, Friedemann F; Gjertsen, Bjørn Tore BT; Reikvam, Håkon H
Publication Date: 2023-04

Variant appearance in text: TP53: 818G>A
PubMed Link: 37187497
Variant Present in the following documents:
  • Main text
  • jh-12-092.pdf
View BVdb publication page



A Retrospective Multi-Institutional Cohort Analysis of Clinical Characteristics and Outcomes in Dedifferentiated Chondrosarcoma.

Cancers
Bui, Nam N; Dietz, Hilary H; Farag, Sheima S; Hirbe, Angela C AC; Wagner, Michael J MJ; Van Tine, Brian A BA; Ganjoo, Kristen K; Jones, Robin L RL; Keedy, Vicki L VL; Davis, Elizabeth J EJ
Publication Date: 2023-05-05

Variant appearance in text: TP53: R273H
PubMed Link: 37174084
Variant Present in the following documents:
  • Main text
  • cancers-15-02617.pdf
View BVdb publication page



Bromodomain protein BRD8 regulates cell cycle progression in colorectal cancer cells through a TIP60-independent regulation of the pre-RC complex.

Iscience
Yamaguchi, Kiyoshi K; Nakagawa, Saya S; Saku, Akari A; Isobe, Yumiko Y; Yamaguchi, Rui R; Sheridan, Paul P; Takane, Kiyoko K; Ikenoue, Tsuneo T; Zhu, Chi C; Miura, Masashi M; Okawara, Yuya Y; Nagatoishi, Satoru S; Kozuka-Hata, Hiroko H; Oyama, Masaaki M; Aikou, Susumu S; Ahiko, Yuka Y; Shida, Dai D; Tsumoto, Kouhei K; Miyano, Satoru S; Imoto, Seiya S; Furukawa, Yoichi Y
Publication Date: 2023-04-21

Variant appearance in text: TP53: R273H
PubMed Link: 37123243
Variant Present in the following documents:
  • mmc1.pdf
View BVdb publication page



A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression.

Cancer Cell
Hutten, Stefan J SJ; de Bruijn, Roebi R; Lutz, Catrin C; Badoux, Madelon M; Eijkman, Timo T; Chao, Xue X; Ciwinska, Marta M; Sheinman, Michael M; Messal, Hendrik H; Herencia-Ropero, Andrea A; Kristel, Petra P; Mulder, Lennart L; van der Waal, Rens R; Sanders, Joyce J; Almekinders, Mathilde M MM; Llop-Guevara, Alba A; Davies, Helen R HR; van Haren, Matthijs J MJ; Martin, Nathaniel I NI; Behbod, Fariba F; Nik-Zainal, Serena S; Serra, Violeta V; van Rheenen, Jacco J; Lips, Esther H EH; Wessels, Lodewyk F A LFA; , ; Wesseling, Jelle J; Scheele, Colinda L G J CLGJ; Jonkers, Jos J
Publication Date: 2023-04-24

Variant appearance in text: TP53: R273H; rs28934576
PubMed Link: 37116492
Variant Present in the following documents:
  • mmc3.xlsx, sheet 1
View BVdb publication page



TP53 somatic mutations in Asian breast cancer are associated with subtype-specific effects.

Breast Cancer Research : Bcr
Ragu, Mohana Eswari ME; Lim, Joanna Mei Ch'wan JMC; Ng, Pei-Sze PS; Yip, Cheng-Har CH; Rajadurai, Pathmanathan P; Teo, Soo-Hwang SH; Pan, Jia-Wern JW
Publication Date: 2023-04-26

Variant appearance in text: TP53: 818G>A; R273H
PubMed Link: 37101199
Variant Present in the following documents:
  • 13058_2023_1635_MOESM1_ESM.pdf
View BVdb publication page



Prevalence, causes and impact of TP53-loss phenocopying events in human tumors.

Bmc Biology
Fito-Lopez, Bruno B; Salvadores, Marina M; Alvarez, Miguel-Martin MM; Supek, Fran F
Publication Date: 2023-04-24

Variant appearance in text: p53: R273H
PubMed Link: 37095494
Variant Present in the following documents:
  • 12915_2023_Article_1595.pdf
View BVdb publication page



Utilizing cell-free DNA to predict risk of developing brain metastases in patients with metastatic breast cancer.

Npj Breast Cancer
Vidula, Neelima N; Niemierko, Andrzej A; Hesler, Katherine K; Ryan, Lianne L; Moy, Beverly B; Isakoff, Steven S; Ellisen, Leif L; Juric, Dejan D; Bardia, Aditya A
Publication Date: 2023-04-19

Variant appearance in text: TP53: R273H
PubMed Link: 37076495
Variant Present in the following documents:
  • 41523_2023_528_MOESM1_ESM.pdf
View BVdb publication page



Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis.

Cell Death Discovery
Romanovsky, Eva E; Kluck, Klaus K; Ourailidis, Iordanis I; Menzel, Michael M; Beck, Susanne S; Ball, Markus M; Kazdal, Daniel D; Christopoulos, Petros P; Schirmacher, Peter P; Stiewe, Thorsten T; Stenzinger, Albrecht A; Budczies, Jan J
Publication Date: 2023-04-14

Variant appearance in text: TP53: R273H
PubMed Link: 37059713
Variant Present in the following documents:
  • Main text
  • 41420_2023_Article_1413.pdf
View BVdb publication page



Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Publication Date: 2023-04-03

Variant appearance in text: TP53: R273H
PubMed Link: 37012232
Variant Present in the following documents:
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 3
View BVdb publication page



Precise pancreatic cancer therapy through targeted degradation of mutant p53 protein by cerium oxide nanoparticles.

Journal Of Nanobiotechnology
Zhang, Hao H; Zhang, Wang W; Hu, Bochuan B; Qin, Xiaohua X; Yi, Tianxiang T; Ye, Yayi Y; Huang, Xiaowan X; Song, Yang Y; Yang, Zhenyu Z; Qian, Jieying J; Zhang, Yunjiao Y
Publication Date: 2023-04-01

Variant appearance in text: p53: R273H
PubMed Link: 37005668
Variant Present in the following documents:
  • Main text
  • 12951_2023_Article_1867.pdf
View BVdb publication page



Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers.

Bmc Cancer
Xie, Jianjiang J; Yao, Weishen W; Chen, Lingxiu L; Zhu, Wenjun W; Liu, Qiang Q; Geng, Geng G; Fang, Jing J; Zhao, Yang Y; Xiao, Li L; Huang, Zhenhua Z; Zhao, Jing J
Publication Date: 2023-03-31

Variant appearance in text: TP53: Arg273His
PubMed Link: 37004022
Variant Present in the following documents:
  • 12885_2023_10674_MOESM3_ESM.xlsx, sheet 1
  • 12885_2023_10674_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Altered cytoplasmic and nuclear ADP-ribosylation levels analyzed with an improved ADP-ribose binder are a prognostic factor in renal cell carcinoma.

The Journal Of Pathology. Clinical Research
Schraml, Peter P; Aimi, Fabio F; Zoche, Martin M; Aguilera-Garcia, Domingo D; Arnold, Fabian F; Moch, Holger H; Hottiger, Michael O MO
Publication Date: 2023-03-31

Variant appearance in text: TP53: R273H
PubMed Link: 36999983
Variant Present in the following documents:
  • CJP2-9-273-s001.xlsx, sheet 21
View BVdb publication page



Rewired m6A epitranscriptomic networks link mutant p53 to neoplastic transformation.

Nature Communications
Xu, An A; Liu, Mo M; Huang, Mo-Fan MF; Zhang, Yang Y; Hu, Ruifeng R; Gingold, Julian A JA; Liu, Ying Y; Zhu, Dandan D; Chien, Chian-Shiu CS; Wang, Wei-Chen WC; Liao, Zian Z; Yuan, Fei F; Hsu, Chih-Wei CW; Tu, Jian J; Yu, Yao Y; Rosen, Taylor T; Xiong, Feng F; Jia, Peilin P; Yang, Yi-Ping YP; Bazer, Danielle A DA; Chen, Ya-Wen YW; Li, Wenbo W; Huff, Chad D CD; Zhu, Jay-Jiguang JJ; Aguilo, Francesca F; Chiou, Shih-Hwa SH; Boles, Nathan C NC; Lai, Chien-Chen CC; Hung, Mien-Chie MC; Zhao, Zhongming Z; Van Nostrand, Eric L EL; Zhao, Ruiying R; Lee, Dung-Fang DF
Publication Date: 2023-03-27

Variant appearance in text: p53: R273H
PubMed Link: 36973285
Variant Present in the following documents:
  • Main text
  • 41467_2023_Article_37398.pdf
  • 41467_2023_37398_MOESM1_ESM.pdf
View BVdb publication page



Characteristics and prognosis of rrDLBCL with TP53 mutations and a high-risk subgroup represented by the co-mutations of DDX3X-TP53.

Cancer Medicine
Gao, Fan F; Hu, Kai K; Zheng, Peihao P; Shi, Hui H; Ke, Xiaoyan X
Publication Date: 2023-03-27

Variant appearance in text: TP53: 818G>A; rs28934576
PubMed Link: 36971051
Variant Present in the following documents:
  • Main text
  • CAM4-12-10267.pdf
  • CAM4-12-10267-s002.xlsx, sheet 1
  • CAM4-12-10267-s001.xlsx, sheet 1
View BVdb publication page



Pediatric brain tumors: A neuropathologist's approach to the integrated diagnosis.

Frontiers In Pediatrics
Viaene, Angela N AN
Publication Date: 2023

Variant appearance in text: TP53: R273H
PubMed Link: 36969278
Variant Present in the following documents:
  • Main text
  • fped-11-1143363.pdf
View BVdb publication page



Different impacts of TP53 mutations on cell cycle-related gene expression among cancer types.

Scientific Reports
Sasaki, Keiju K; Takahashi, Shin S; Ouchi, Kota K; Otsuki, Yasufumi Y; Wakayama, Shonosuke S; Ishioka, Chikashi C
Publication Date: 2023-03-24

Variant appearance in text: p53: R273H
PubMed Link: 36964217
Variant Present in the following documents:
  • 41598_2023_32092_MOESM1_ESM.xlsx, sheet 4
  • 41598_2023_Article_32092.pdf
View BVdb publication page



A strategy for the treatment of gastrointestinal cancer: Targeting tumor senescent cells.

Frontiers In Molecular Biosciences
Liu, Yujing Y; Zhang, Qiang Q; Ni, Wenjing W; Ji, Guang G; Xu, Hanchen H
Publication Date: 2023

Variant appearance in text: p53: R273H
PubMed Link: 36950520
Variant Present in the following documents:
  • Main text
  • fmolb-10-1139840.pdf
View BVdb publication page



RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer.

Nature
Jbara, Amina A; Lin, Kuan-Ting KT; Stossel, Chani C; Siegfried, Zahava Z; Shqerat, Haya H; Amar-Schwartz, Adi A; Elyada, Ela E; Mogilevsky, Maxim M; Raitses-Gurevich, Maria M; Johnson, Jared L JL; Yaron, Tomer M TM; Ovadia, Ofek O; Jang, Gun Ho GH; Danan-Gotthold, Miri M; Cantley, Lewis C LC; Levanon, Erez Y EY; Gallinger, Steven S; Krainer, Adrian R AR; Golan, Talia T; Karni, Rotem R
Publication Date: 2023-03-22

Variant appearance in text: TP53: R273H
PubMed Link: 36949200
Variant Present in the following documents:
  • 41586_2023_5820_MOESM4_ESM.xlsx, sheet 3
  • 41586_2023_5820_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Novel Scheme for Defining the Clinical Implications of TP53 Mutations in Myeloid Neoplasia.

Research Square
Bahaj, Waled W; Kewan, Tariq T; Gurnari, Carmelo C; Durmaz, Arda A; Ponvilawan, Ben B; Pandit, Ishani I; Kubota, Yasuo Y; Ogbue, Olisaemeka D OD; Zawit, Misam M; Madanat, Yazan Y; Bat, Taha T; Balasubramanian, Suresh K SK; Awada, Hussein H; Ahmed, Ramsha R; Mori, Minako M; Meggendorfer, Manja M; Haferlach, Torsten T; Visconte, Valeria V; Maciejewski, Jaroslaw P JP
Publication Date: 2023-03-09

Variant appearance in text: TP53: R273H
PubMed Link: 36945617
Variant Present in the following documents:
  • nihpp-rs2656206v1.pdf
View BVdb publication page



Relapse timing is associated with distinct evolutionary dynamics in DLBCL.

Medrxiv : The Preprint Server For Health Sciences
Hilton, Laura K LK; Ngu, Henry S HS; Collinge, Brett B; Dreval, Kostiantyn K; Ben-Neriah, Susana S; Rushton, Christopher K CK; Wong, Jasper C H JCH; Cruz, Manuela M; Roth, Andrew A; Boyle, Merrill M; Meissner, Barbara B; Slack, Graham W GW; Farinha, Pedro P; Craig, Jeffrey W JW; Gerrie, Alina S AS; Freeman, Ciara L CL; Villa, Diego D; Crump, Michael M; Shepherd, Lois L; Hay, Annette E AE; Kuruvilla, John J; Savage, Kerry J KJ; Kridel, Robert R; Karsan, Aly A; Marra, Marco A MA; Sehn, Laurie H LH; Steidl, Christian C; Morin, Ryan D RD; Scott, David W DW
Publication Date: 2023-03-08

Variant appearance in text: TP53: 818G>A; R273H; rs28934576
PubMed Link: 36945587
Variant Present in the following documents:
  • media-1.xlsx, sheet 14
View BVdb publication page



Identification of antigenic epitopes recognized by tumor infiltrating lymphocytes in high grade serous ovarian cancer by multi-omics profiling of the auto-antigen repertoire.

Cancer Immunology, Immunotherapy : Cii
Millar, Douglas G DG; Yang, S Y Cindy SYC; Sayad, Azin A; Zhao, Qingchuan Q; Nguyen, Linh T LT; Warner, Kathrin K; Sangster, Ami G AG; Nakatsugawa, Munehide M; Murata, Kenji K; Wang, Ben X BX; Shaw, Patricia P; Clarke, Blaise B; Bernardini, Marcus Q MQ; Pugh, Trevor T; Thibault, Pierre P; Hirano, Naoto N; Perreault, Claude C; Ohashi, Pamela S PS
Publication Date: 2023-03-21

Variant appearance in text: TP53: R273H
PubMed Link: 36943460
Variant Present in the following documents:
  • 262_2023_3413_MOESM1_ESM.pdf
View BVdb publication page



Tumor senescence leads to poor survival and therapeutic resistance in human breast cancer.

Frontiers In Oncology
Zhai, Jingtong J; Han, Jiashu J; Li, Cong C; Lv, Dan D; Ma, Fei F; Xu, Binghe B
Publication Date: 2023

Variant appearance in text: TP53: 818G>A
PubMed Link: 36937388
Variant Present in the following documents:
  • Main text
  • fonc-13-1097513.pdf
View BVdb publication page



Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology.

Nature Medicine
Sturm, Dominik D; Capper, David D; Andreiuolo, Felipe F; Gessi, Marco M; Kölsche, Christian C; Reinhardt, Annekathrin A; Sievers, Philipp P; Wefers, Annika K AK; Ebrahimi, Azadeh A; Suwala, Abigail K AK; Gielen, Gerrit H GH; Sill, Martin M; Schrimpf, Daniel D; Stichel, Damian D; Hovestadt, Volker V; Daenekas, Bjarne B; Rode, Agata A; Hamelmann, Stefan S; Previti, Christopher C; Jäger, Natalie N; Buchhalter, Ivo I; Blattner-Johnson, Mirjam M; Jones, Barbara C BC; Warmuth-Metz, Monika M; Bison, Brigitte B; Grund, Kerstin K; Sutter, Christian C; Hirsch, Steffen S; Dikow, Nicola N; Hasselblatt, Martin M; Schüller, Ulrich U; Gerber, Nicolas U NU; White, Christine L CL; Buntine, Molly K MK; Kinross, Kathryn K; Algar, Elizabeth M EM; Hansford, Jordan R JR; Gottardo, Nicholas G NG; Hernáiz Driever, Pablo P; Gnekow, Astrid A; Witt, Olaf O; Müller, Hermann L HL; Calaminus, Gabriele G; Fleischhack, Gudrun G; Kordes, Uwe U; Mynarek, Martin M; Rutkowski, Stefan S; Frühwald, Michael C MC; Kramm, Christof M CM; von Deimling, Andreas A; Pietsch, Torsten T; Sahm, Felix F; Pfister, Stefan M SM; Jones, David T W DTW
Publication Date: 2023-03-16

Variant appearance in text: TP53: R273H
PubMed Link: 36928815
Variant Present in the following documents:
  • 41591_2023_2255_MOESM3_ESM.xlsx, sheet 5
View BVdb publication page



Targeting the Ezrin Adaptor Protein Sensitizes Metastatic Breast Cancer Cells to Chemotherapy and Reduces Neoadjuvant Therapy-induced Metastasis.

Cancer Research Communications
Hoskin, Victoria V; Ghaffari, Abdi A; Laight, Brian J BJ; SenGupta, Sandip S; Madarnas, Yolanda Y; Nicol, Christopher J B CJB; Elliott, Bruce E BE; Varma, Sonal S; Greer, Peter A PA
Publication Date: 2022-06

Variant appearance in text: TP53: R273H
PubMed Link: 36923551
Variant Present in the following documents:
  • crc-21-0117-s01.pdf
View BVdb publication page



Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.

Cancer Research Communications
White, Jason A JA; Kaninjing, Ernest T ET; Adeniji, Kayode A KA; Jibrin, Paul P; Obafunwa, John O JO; Ogo, Chidiebere N CN; Mohammed, Faruk F; Popoola, Ademola A; Fatiregun, Omolara A OA; Oluwole, Olabode P OP; Karanam, Balasubramanyam B; Elhussin, Isra I; Ambs, Stefan S; Tang, Wei W; Davis, Melissa M; Polak, Paz P; Campbell, Moray J MJ; Brignole, Kathryn R KR; Rotimi, Solomon O SO; Dean-Colomb, Windy W; Odedina, Folake T FT; Martin, Damali N DN; Yates, Clayton C
Publication Date: 2022-09

Variant appearance in text: TP53: 818G>A; Arg273His; rs28934576
PubMed Link: 36922933
Variant Present in the following documents:
  • crc-22-0136-s01.xlsx, sheet 3
  • crc-22-0136-s01.xlsx, sheet 1
View BVdb publication page



Pharmacogenomic profiling reveals molecular features of chemotherapy resistance in IDH wild-type primary glioblastoma.

Genome Medicine
Nam, Yoonhee Y; Koo, Harim H; Yang, Yingxi Y; Shin, Sang S; Zhu, Zhihan Z; Kim, Donggeon D; Cho, Hee Jin HJ; Mu, Quanhua Q; Choi, Seung Won SW; Sa, Jason K JK; Seo, Yun Jee YJ; Kim, Yejin Y; Lee, Kyoungmin K; Oh, Jeong-Woo JW; Kwon, Yong-Jun YJ; Park, Woong-Yang WY; Kong, Doo-Sik DS; Seol, Ho Jun HJ; Lee, Jung-Il JI; Park, Chul-Kee CK; Lee, Hye Won HW; Yoon, Yeup Y; Wang, Jiguang J
Publication Date: 2023-03-13

Variant appearance in text: TP53: R273H
PubMed Link: 36915208
Variant Present in the following documents:
  • 13073_2023_1165_MOESM1_ESM.xlsx, sheet 2
View BVdb publication page



A generalizable machine learning framework for classifying DNA repair defects using ctDNA exomes.

Npj Precision Oncology
Ritch, Elie J EJ; Herberts, Cameron C; Warner, Evan W EW; Ng, Sarah W S SWS; Kwan, Edmond M EM; Bacon, Jack V W JVW; Bernales, Cecily Q CQ; Schönlau, Elena E; Fonseca, Nicolette M NM; Giri, Veda N VN; Maurice-Dror, Corinne C; Vandekerkhove, Gillian G; Jones, Steven J M SJM; Chi, Kim N KN; Wyatt, Alexander W AW
Publication Date: 2023-03-13

Variant appearance in text: TP53: R273H
PubMed Link: 36914848
Variant Present in the following documents:
  • 41698_2023_366_MOESM2_ESM.xlsx, sheet 4
View BVdb publication page



Recapitulating thyroid cancer histotypes through engineering embryonic stem cells.

Nature Communications
Veschi, Veronica V; Turdo, Alice A; Modica, Chiara C; Verona, Francesco F; Di Franco, Simone S; Gaggianesi, Miriam M; Tirrò, Elena E; Di Bella, Sebastiano S; Iacono, Melania Lo ML; Pantina, Vincenzo Davide VD; Porcelli, Gaetana G; Mangiapane, Laura Rosa LR; Bianca, Paola P; Rizzo, Aroldo A; Sciacca, Elisabetta E; Pillitteri, Irene I; Vella, Veronica V; Belfiore, Antonino A; Bongiorno, Maria Rita MR; Pistone, Giuseppe G; Memeo, Lorenzo L; Colarossi, Lorenzo L; Giuffrida, Dario D; Colarossi, Cristina C; Vigneri, Paolo P; Todaro, Matilde M; Stassi, Giorgio G
Publication Date: 2023-03-11

Variant appearance in text: TP53: 818G>A; Arg273His
PubMed Link: 36906579
Variant Present in the following documents:
  • 41467_2023_36922_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



Extracellular Vesicle-DNA: The Next Liquid Biopsy Biomarker for Early Cancer Diagnosis?

Cancers
Tatischeff, Irène I
Publication Date: 2023-02-24

Variant appearance in text: TP53: R273H
PubMed Link: 36900248
Variant Present in the following documents:
  • Main text
View BVdb publication page



Evaluation of AlphaFold structure-based protein stability prediction on missense variations in cancer.

Frontiers In Genetics
Keskin Karakoyun, Hilal H; Yüksel, Şirin K ŞK; Amanoglu, Ilayda I; Naserikhojasteh, Lara L; Yeşilyurt, Ahmet A; Yakıcıer, Cengiz C; Timuçin, Emel E; Akyerli, Cemaliye B CB
Publication Date: 2023

Variant appearance in text: TP53: R273H
PubMed Link: 36896237
Variant Present in the following documents:
  • Table1.xlsx, sheet 1
View BVdb publication page



Combinatorial BCL-2 family expression in Acute Myeloid Leukemia Stem Cells predicts clinical response to Azacitidine/Venetoclax.

Cancer Discovery
Waclawiczek, Alexander A; Leppa, Aino-Maija AM; Renders, Simon S; Stumpf, Karolin K; Reyneri, Cecilia C; Betz, Barbara B; Janssen, Maike M; Shahswar, Rabia R; Donato, Elisa E; Karpova, Darja D; Thiel, Vera V; Unglaub, Julia M JM; Grabowski, Susanna S; Gryzik, Stefanie S; Vierbaum, Lisa L; Schlenk, Richard F RF; Rollig, Christoph C; Hundemer, Michael M; Pabst, Caroline C; Heuser, Michael M; Raffel, Simon S; Muller-Tidow, Carsten C; Sauer, Tim T; Trumpp, Andreas A
Publication Date: 2023-03-09

Variant appearance in text: TP53: 818G>A; R273H
PubMed Link: 36892565
Variant Present in the following documents:
  • cd-22-0939_supplementary_tables_1-7_suppst1.xlsx, sheet 2
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Integration of deep learning with Ramachandran plot molecular dynamics simulation for genetic variant classification.

Iscience
Tam, Benjamin B; Qin, Zixin Z; Zhao, Bojin B; Wang, San Ming SM; Lei, Chon Lok CL
Publication Date: 2023-03-17

Variant appearance in text: TP53: 818G>A; R273H
PubMed Link: 36879825
Variant Present in the following documents:
  • mmc3.xlsx, sheet 1
  • mmc2.xlsx, sheet 1
  • mmc4.xlsx, sheet 1
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A Phenogenetic Axis that Modulates Clinical Manifestation and Predicts Treatment Outcome in Primary Myeloid Neoplasms.

Cancer Research Communications
Shen, Qiujin Q; Feng, Yahui Y; Gong, Xiaowen X; Jia, Yujiao Y; Gao, Qingyan Q; Jiao, Xiaokang X; Qi, Saibing S; Liu, Xueou X; Wei, Hui H; Huang, Bingqing B; Zhao, Ningning N; Song, Xiaoqiang X; Ma, Yueshen Y; Liang, Shihao S; Zhang, Donglei D; Qin, Li L; Wang, Ying Y; Qu, Shiqiang S; Zou, Yao Y; Chen, Yumei Y; Guo, Ye Y; Yi, Shuhua S; An, Gang G; Jiao, Zengtao Z; Zhang, Song S; Li, Linfeng L; Yan, Jun J; Wang, Huijun H; Song, Zhen Z; Mi, Yingchang Y; Qiu, Lugui L; Zhu, Xiaofan X; Wang, Jianxiang J; Xiao, Zhijian Z; Chen, Junren J
Publication Date: 2022-04

Variant appearance in text: TP53: 818G>A; R273H
PubMed Link: 36873623
Variant Present in the following documents:
  • crc-21-0194-s05.xlsx, sheet 1
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Nanomedicine for autophagy modulation in cancer therapy: a clinical perspective.

Cell & Bioscience
López-Méndez, Tania B TB; Sánchez-Álvarez, Miguel M; Trionfetti, Flavia F; Pedraz, José L JL; Tripodi, Marco M; Cordani, Marco M; Strippoli, Raffaele R; González-Valdivieso, Juan J
Publication Date: 2023-03-04

Variant appearance in text: p53: R273H
PubMed Link: 36871010
Variant Present in the following documents:
  • 13578_2023_Article_986.pdf
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USP35 promotes cell proliferation and chemotherapeutic resistance through stabilizing FUCA1 in colorectal cancer.

Oncogenesis
Xiao, Yi Y; Jiang, Xiaoyu X; Yin, Ke K; Miao, Tianshu T; Lu, Hanlin H; Wang, Wenqing W; Ma, Lijuan L; Zhao, Yinghui Y; Liu, Chunyan C; Qiao, Yun Y; Zhang, Pengju P
Publication Date: 2023-03-03

Variant appearance in text: p53: R273H
PubMed Link: 36864055
Variant Present in the following documents:
  • Main text
  • 41389_2023_Article_458.pdf
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Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery
Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI
Publication Date: 2023-03-02

Variant appearance in text: TP53: 818G>A; R273H; rs28934576
PubMed Link: 36862804
Variant Present in the following documents:
  • cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 6
View BVdb publication page