TP53 c.805_807delinsGAG ;(p.S269E)

Variant ID: 17-7577131-GCT-CTC

NM_000546.5(TP53):c.805_807delinsGAG;(p.S269E)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Inhibition of p53 and/or AKT as a new therapeutic approach specifically targeting ALT cancers.

Protein & Cell
Ge, Yuanlong Y; Wu, Shu S; Zhang, Zepeng Z; Li, Xiaocui X; Li, Feng F; Yan, Siyu S; Liu, Haiying H; Huang, Junjiu J; Zhao, Yong Y
Publication Date: 2019-11

Variant appearance in text: p53: s269e
PubMed Link: 31115790
Variant Present in the following documents:
  • Main text
  • 13238_2019_Article_634.pdf
View BVdb publication page



Aurora B interacts with NIR-p53, leading to p53 phosphorylation in its DNA-binding domain and subsequent functional suppression.

The Journal Of Biological Chemistry
Wu, Liming L; Ma, Chi A CA; Zhao, Yongge Y; Jain, Ashish A
Publication Date: 2011-01-21

Variant appearance in text: p53: S269E
PubMed Link: 20959462
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization.

Biochemical And Biophysical Research Communications
An, Rong R; da Silva Xavier, Gabriela G; Semplici, Francesca F; Vakhshouri, Saharnaz S; Hao, Huai-Xiang HX; Rutter, Jared J; Pagano, Mario A MA; Meggio, Flavio F; Pinna, Lorenzo A LA; Rutter, Guy A GA
Publication Date: 2010-08-20

Variant appearance in text: p53: S269E
PubMed Link: 20637728
Variant Present in the following documents:
  • Main text
View BVdb publication page