TP53 c.805_806delinsGC ;(p.S269A)

Variant ID: 17-7577132-CT-GC

NM_000546.5(TP53):c.805_806delinsGC;(p.S269A)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Aurora B interacts with NIR-p53, leading to p53 phosphorylation in its DNA-binding domain and subsequent functional suppression.

The Journal Of Biological Chemistry
Wu, Liming L; Ma, Chi A CA; Zhao, Yongge Y; Jain, Ashish A
Publication Date: 2011-01-21

Variant appearance in text: p53: S269A
PubMed Link: 20959462
Variant Present in the following documents:
  • Main text
View BVdb publication page



A novel p53 phosphorylation site within the MDM2 ubiquitination signal: I. phosphorylation at SER269 in vivo is linked to inactivation of p53 function.

The Journal Of Biological Chemistry
Fraser, Jennifer A JA; Vojtesek, Borivoj B; Hupp, Ted R TR
Publication Date: 2010-11-26

Variant appearance in text: p53: S269A
PubMed Link: 20851891
Variant Present in the following documents:
  • Main text
View BVdb publication page



A novel p53 phosphorylation site within the MDM2 ubiquitination signal: II. a model in which phosphorylation at SER269 induces a mutant conformation to p53.

The Journal Of Biological Chemistry
Fraser, Jennifer A JA; Madhumalar, Arumugam A; Blackburn, Elizabeth E; Bramham, Janice J; Walkinshaw, Malcolm D MD; Verma, Chandra C; Hupp, Ted R TR
Publication Date: 2010-11-26

Variant appearance in text: p53: S269A
PubMed Link: 20847049
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization.

Biochemical And Biophysical Research Communications
An, Rong R; da Silva Xavier, Gabriela G; Semplici, Francesca F; Vakhshouri, Saharnaz S; Hao, Huai-Xiang HX; Rutter, Jared J; Pagano, Mario A MA; Meggio, Flavio F; Pinna, Lorenzo A LA; Rutter, Guy A GA
Publication Date: 2010-08-20

Variant appearance in text: p53: S269A
PubMed Link: 20637728
Variant Present in the following documents:
  • Main text
View BVdb publication page