TP53 c.766_767insAA ;(p.T256Kfs*90)

Variant ID: 17-7577514-G-GTT

NM_000546.5(TP53):c.766_767insAA;(p.T256Kfs*90)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Inflammatory conversion of quiescent osteoblasts by metastatic breast cancer cells through pERK1/2 aggravates cancer-induced bone destruction.

Bone Research
Back, Jungho J; Nguyen, Minh Nam MN; Li, Lu L; Lee, Saelim S; Lee, Inkyu I; Chen, Fancheng F; Gillinov, Lauren L; Chung, Yeon-Ho YH; Alder, Kareme D KD; Kwon, Hyuk-Kwon HK; Yu, Kristin E KE; Dussik, Christopher M CM; Hao, Zichen Z; Flores, Michael J MJ; Kim, Yoseph Y; Ibe, Izuchukwu K IK; Munger, Alana M AM; Seo, Sung Wook SW; Lee, Francis Y FY
Publication Date: 2021-09-29

Variant appearance in text: TP53: T256fs*90
PubMed Link: 34588427
Variant Present in the following documents:
  • 41413_2021_158_MOESM2_ESM.pdf
View BVdb publication page



Oncogenic TRIM37 Links Chemoresistance and Metastatic Fate in Triple-Negative Breast Cancer.

Cancer Research
Przanowski, Piotr P; Lou, Song S; Tihagam, Rachisan Djiake RD; Mondal, Tanmoy T; Conlan, Caroline C; Shivange, Gururaj G; Saltani, Ilyas I; Singh, Chandrajeet C; Xing, Kun K; Morris, Benjamin B BB; Mayo, Marty W MW; Teixeira, Luis L; Lehmann-Che, Jacqueline J; Tushir-Singh, Jogender J; Bhatnagar, Sanchita S
Publication Date: 2020-11-01

Variant appearance in text: p53: T256Kfs*90
PubMed Link: 32855208
Variant Present in the following documents:
  • Main text
View BVdb publication page



Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen.

Nature Communications
Menden, Michael P MP; Wang, Dennis D; Mason, Mike J MJ; Szalai, Bence B; Bulusu, Krishna C KC; Guan, Yuanfang Y; Yu, Thomas T; Kang, Jaewoo J; Jeon, Minji M; Wolfinger, Russ R; Nguyen, Tin T; Zaslavskiy, Mikhail M; , ; Jang, In Sock IS; Ghazoui, Zara Z; Ahsen, Mehmet Eren ME; Vogel, Robert R; Neto, Elias Chaibub EC; Norman, Thea T; Tang, Eric K Y EKY; Garnett, Mathew J MJ; Veroli, Giovanni Y Di GYD; Fawell, Stephen S; Stolovitzky, Gustavo G; Guinney, Justin J; Dry, Jonathan R JR; Saez-Rodriguez, Julio J
Publication Date: 2019-06-17

Variant appearance in text: TP53: T256fs*90
PubMed Link: 31209238
Variant Present in the following documents:
  • 41467_2019_9799_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



Oncogenic PIK3CA mutations increase dependency on the mRNA cap methyltransferase, RNMT, in breast cancer cells.

Open Biology
Dunn, Sianadh S; Lombardi, Olivia O; Lukoszek, Radoslaw R; Cowling, Victoria H VH
Publication Date: 2019-04-26

Variant appearance in text: TP53: T256fs*90
PubMed Link: 30991934
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Landscape of Pharmacogenomic Interactions in Cancer.

Cell
Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ
Publication Date: 2016-07-28

Variant appearance in text: TP53: 766_767insAA; T256fs*90
PubMed Link: 27397505
Variant Present in the following documents:
  • mmc3.xlsx, sheet 3
View BVdb publication page