Variant ID: 17-7577538-C-T

NM_000546.5(TP53):c.743G>A;(p.R248Q)

This variant was identified in 1126 publications

View GRCh38 version.




Publications:


Nuclear Vav3 is required for polycomb repression complex-1 activity in B-cell lymphoblastic leukemogenesis.

Nature Communications
Nayak, R C RC; Chang, K H KH; Singh, A K AK; Kotliar, M M; Desai, M M; Wellendorf, A M AM; Wunderlich, M M; Bartram, J J; Mizukawa, B B; Cuadrado, M M; Dexheimer, P P; Barski, A A; Bustelo, X R XR; Nassar, N N NN; Cancelas, J A JA
Publication Date: 2022-06-01

Variant appearance in text: TP53: R248Q
PubMed Link: 35650206
Variant Present in the following documents:
  • Main text
  • 41467_2022_Article_30651.pdf
View BVdb publication page



Convergent evolution and multi-wave clonal invasion in H3 K27-altered diffuse midline gliomas treated with a PDGFR inhibitor.

Acta Neuropathologica Communications
Arunachalam, Sasi S; Szlachta, Karol K; Brady, Samuel W SW; Ma, Xiaotu X; Ju, Bensheng B; Shaner, Bridget B; Mulder, Heather L HL; Easton, John J; Raphael, Benjamin J BJ; Myers, Matthew M; Tinkle, Christopher C; Allen, Sariah J SJ; Orr, Brent A BA; Wetmore, Cynthia J CJ; Baker, Suzanne J SJ; Zhang, Jinghui J
Publication Date: 2022-05-31

Variant appearance in text: TP53: R248Q
PubMed Link: 35642016
Variant Present in the following documents:
  • Main text
  • 40478_2022_Article_1381.pdf
  • 40478_2022_1381_MOESM2_ESM.pdf
View BVdb publication page



Whole-Exome Sequencing Reveals Clinical Potential of Circulating Tumor DNA from Peritoneal Fluid and Plasma in Endometrial Cancer.

Cancers
Ju, Hye-Yeon HY; Ho, Jung Yoon JY; Kang, Jun J; Hur, Soo Young SY; Kim, Sejin S; Choi, Youn Jin YJ; Han, Mi-Ryung MR
Publication Date: 2022-05-19

Variant appearance in text: TP53: R248Q
PubMed Link: 35626111
Variant Present in the following documents:
  • Main text
  • cancers-14-02506.pdf
View BVdb publication page



Are We Moving the Needle for Patients with TP53-Mutated Acute Myeloid Leukemia?

Cancers
Shallis, Rory M RM; Bewersdorf, Jan P JP; Stahl, Maximilian F MF; Halene, Stephanie S; Zeidan, Amer M AM
Publication Date: 2022-05-14

Variant appearance in text: TP53: R248Q
PubMed Link: 35626039
Variant Present in the following documents:
  • Main text
  • cancers-14-02434.pdf
View BVdb publication page



TP53 Pathogenic Variants in Early-Onset Breast Cancer Patients Fulfilling Hereditary Breast and Ovary Cancer and Li-Fraumeni-like Syndromes.

Biomolecules
da Silva, Paula Francinete Faustino PFF; Goveia, Rebeca Mota RM; Teixeira, Thaís Bomfim TB; Gamba, Bruno Faulin BF; de Lima, Aliny Pereira AP; Rogatto, Sílvia Regina SR; Silveira-Lacerda, Elisângela de Paula EP
Publication Date: 2022-04-27

Variant appearance in text: TP53: 743G>A
PubMed Link: 35625568
Variant Present in the following documents:
  • Main text
  • biomolecules-12-00640.pdf
View BVdb publication page



Pathophysiologic and clinical implications of molecular profiles resultant from deletion 5q.

Ebiomedicine
Adema, Vera V; Palomo, Laura L; Walter, Wencke W; Mallo, Mar M; Hutter, Stephan S; La Framboise, Thomas T; Arenillas, Leonor L; Meggendorfer, Manja M; Radivoyevitch, Tomas T; Xicoy, Blanca B; Pellagatti, Andrea A; Haferlach, Claudia C; Boultwood, Jacqueline J; Kern, Wolfgang W; Visconte, Valeria V; Sekeres, Mikkael M; Barnard, John J; Haferlach, Torsten T; Solé, Francesc F; Maciejewski, Jaroslaw P JP
Publication Date: 2022-05-23

Variant appearance in text: TP53: 743G>A; Arg248Gln
PubMed Link: 35617825
Variant Present in the following documents:
  • mmc3.xlsx
View BVdb publication page



Synthetic lethality between TP53 and ENDOD1.

Nature Communications
Tang, Zizhi Z; Zeng, Ming M; Wang, Xiaojun X; Guo, Chang C; Yue, Peng P; Zhang, Xiaohu X; Lou, Huiqiang H; Chen, Jun J; Mu, Dezhi D; Kong, Daochun D; Carr, Antony M AM; Liu, Cong C
Publication Date: 2022-05-23

Variant appearance in text: TP53: R248Q
PubMed Link: 35606358
Variant Present in the following documents:
  • Main text
  • 41467_2022_30311_MOESM1_ESM.pdf
  • 41467_2022_Article_30311.pdf
View BVdb publication page



Dynamic change of variant allele frequency reveals disease status, clonal evolution and survival in pediatric relapsed B-cell acute lymphoblastic leukaemia.

Clinical And Translational Medicine
Wu, Shuiyan S; Liu, Lixia L; Chu, Xinran X; Zheng, Jiajia J; Chen, Zixing Z; Gao, Li L; Xiao, Peifang P; Lu, Jun J; Ji, Qi Q; Ling, Jing J; Cao, Shanbo S; Pan, Jian J; Qin, Jiayue J; Hu, Shaoyan S
Publication Date: 2022-05

Variant appearance in text: TP53: R248Q
PubMed Link: 35605061
Variant Present in the following documents:
  • Main text
  • CTM2-12-e892.pdf
View BVdb publication page



Distinct landscapes of deleterious variants in DNA damage repair system in ethnic human populations.

Life Science Alliance
Qin, Zixin Z; Huang, Teng T; Guo, Maoni M; Wang, San Ming SM
Publication Date: 2022-09

Variant appearance in text: TP53: 743G>A; Arg248Gln; rs11540652
PubMed Link: 35595529
Variant Present in the following documents:
  • LSA-2021-01319_TableS1.xlsx
  • LSA-2021-01319_TableS3.xlsx
View BVdb publication page



Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients.

Nature Communications
Hassin, Ori O; Nataraj, Nishanth Belugali NB; Shreberk-Shaked, Michal M; Aylon, Yael Y; Yaeger, Rona R; Fontemaggi, Giulia G; Mukherjee, Saptaparna S; Maddalena, Martino M; Avioz, Adi A; Iancu, Ortal O; Mallel, Giuseppe G; Gershoni, Anat A; Grosheva, Inna I; Feldmesser, Ester E; Ben-Dor, Shifra S; Golani, Ofra O; Hendel, Ayal A; Blandino, Giovanni G; Kelsen, David D; Yarden, Yosef Y; Oren, Moshe M
Publication Date: 2022-05-19

Variant appearance in text: p53: R248Q
PubMed Link: 35589715
Variant Present in the following documents:
  • Main text
  • 41467_2022_30481_MOESM2_ESM.pdf
  • 41467_2022_Article_30481.pdf
View BVdb publication page



Pharmacogenetics of hepatocellular carcinoma and cholangiocarcinoma.

Cancer Drug Resistance (Alhambra, Calif.)
Alonso-Peña, Marta M; Sanchez-Martin, Anabel A; Sanchon-Sanchez, Paula P; Soto-Muñiz, Meraris M; Espinosa-Escudero, Ricardo R; Marin, Jose J G JJG
Publication Date: 2019

Variant appearance in text: p53: 743G>A
PubMed Link: 35582588
Variant Present in the following documents:
  • cdr-2-680.pdf
View BVdb publication page



The emerging roles of E3 ubiquitin ligases in ovarian cancer chemoresistance.

Cancer Drug Resistance (Alhambra, Calif.)
Meng, Yang Y; Qiu, Lei L; Zhang, Su S; Han, Junhong J
Publication Date: 2021

Variant appearance in text: p53: R248Q
PubMed Link: 35582023
Variant Present in the following documents:
  • cdr-4-365.pdf
View BVdb publication page



Homologous recombination deficiency in diverse cancer types and its correlation with platinum chemotherapy efficiency in ovarian cancer.

Bmc Cancer
Wen, Hao H; Feng, Zheng Z; Ma, Yutong Y; Liu, Rui R; Ou, Qiuxiang Q; Guo, Qinhao Q; Shen, Yi Y; Wu, Xue X; Shao, Yang Y; Bao, Hua H; Wu, Xiaohua X
Publication Date: 2022-05-16

Variant appearance in text: TP53: 743G>A; R248Q
PubMed Link: 35578198
Variant Present in the following documents:
  • 12885_2022_9602_MOESM9_ESM.xlsx
View BVdb publication page



Response to immunotherapy in KRAS G12C mutated NSCLC: a single-centre retrospective observational study.

Oncotarget
Sciortino, Carolina C; Viglialoro, Valentina V; Nucci, Massimo M; Polito, Mariam Grazia MG; Cortesi, Enrico E; Gelibter, Alain A; Gazzaniga, Paola P; Nicolazzo, Chiara C; Siringo, Marco M; Caponnetto, Salvatore S
Publication Date: 2022

Variant appearance in text: TP53: R248Q
PubMed Link: 35574217
Variant Present in the following documents:
  • oncotarget-13-28230.pdf
View BVdb publication page



Liquid Biopsy in Squamous Cell Carcinoma of the Esophagus and of the Head and Neck.

Frontiers In Medicine
Iacob, Razvan R; Mandea, Matei M; Iacob, Speranta S; Pietrosanu, Catalina C; Paul, Doru D; Hainarosie, Razvan R; Gheorghe, Cristian C
Publication Date: 2022

Variant appearance in text: TP53: R248Q
PubMed Link: 35572996
Variant Present in the following documents:
  • fmed-09-827297.pdf
View BVdb publication page



Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways.

Nature Communications
Zhang, Yiqun Y; Chen, Fengju F; Chandrashekar, Darshan S DS; Varambally, Sooryanarayana S; Creighton, Chad J CJ
Publication Date: 2022-05-13

Variant appearance in text: p53: R248Q
PubMed Link: 35562349
Variant Present in the following documents:
  • 41467_2022_30342_MOESM4_ESM.xlsx
View BVdb publication page



Fundamental immune-oncogenicity trade-offs define driver mutation fitness.

Nature
Hoyos, David D; Zappasodi, Roberta R; Schulze, Isabell I; Sethna, Zachary Z; de Andrade, Kelvin César KC; Bajorin, Dean F DF; Bandlamundi, Chaitanya C; Callahan, Margaret K MK; Funt, Samuel A SA; Hadrup, Sine R SR; Holm, Jeppe S JS; Rosenberg, Jonathan E JE; Shah, Sohrab P SP; Vázquez-García, Ignacio I; Weigelt, Britta B; Wu, Michelle M; Zamarin, Dmitriy D; Campitelli, Laura F LF; Osborne, Edward J EJ; Klinger, Mark M; Robins, Harlan S HS; Khincha, Payal P PP; Savage, Sharon A SA; Balachandran, Vinod P VP; Wolchok, Jedd D JD; Hellmann, Matthew D MD; Merghoub, Taha T; Levine, Arnold J AJ; Łuksza, Marta M; Greenbaum, Benjamin D BD
Publication Date: 2022-05-11

Variant appearance in text: p53: R248Q
PubMed Link: 35545680
Variant Present in the following documents:
  • Main text
  • 41586_2022_4696_MOESM3_ESM.pdf
  • 41586_2022_Article_4696.pdf
  • 41586_2022_4696_MOESM1_ESM.pdf
View BVdb publication page



Mutual exclusivity of ESR1 and TP53 mutations in endocrine resistant metastatic breast cancer.

Npj Breast Cancer
Li, Zheqi Z; Spoelstra, Nicole S NS; Sikora, Matthew J MJ; Sams, Sharon B SB; Elias, Anthony A; Richer, Jennifer K JK; Lee, Adrian V AV; Oesterreich, Steffi S
Publication Date: 2022-05-10

Variant appearance in text: TP53: R248Q
PubMed Link: 35538119
Variant Present in the following documents:
  • 41523_2022_426_MOESM1_ESM.pdf
View BVdb publication page



The dual role of autophagy in acute myeloid leukemia.

Journal Of Hematology & Oncology
Seo, Wonhyoung W; Silwal, Prashanta P; Song, Ik-Chan IC; Jo, Eun-Kyeong EK
Publication Date: 2022-05-07

Variant appearance in text: p53: R248Q
PubMed Link: 35526025
Variant Present in the following documents:
  • 13045_2022_Article_1262.pdf
View BVdb publication page



Paclitaxel and cisplatin with or without cetuximab in metastatic esophageal squamous cell carcinoma: a randomized, multicenter phase II trial.

Innovation (Cambridge (Mass.))
Lu, Zhihao Z; Zhang, Yanqiao Y; Fan, Qingxia Q; Pan, Yueyin Y; Jiang, Da D; Lu, Ping P; Zhang, Jingdong J; Yuan, Xianglin X; Feng, Jifeng J; Yang, Shujun S; Yue, Wenbin W; Zhao, Lin L; Xu, Yunhua Y; Luo, Jinhua J; Shen, Lin L
Publication Date: 2022-05-10

Variant appearance in text: TP53: 743G>A; R248Q
PubMed Link: 35509869
Variant Present in the following documents:
  • mmc2.xlsx
View BVdb publication page



Clonal Hematopoiesis of Indeterminate Potential and Diabetic Kidney Disease: A Nested Case-Control Study.

Kidney International Reports
Denicolò, Sara S; Vogi, Verena V; Keller, Felix F; Thöni, Stefanie S; Eder, Susanne S; Heerspink, Hiddo J L HJL; Rosivall, László L; Wiecek, Andrzej A; Mark, Patrick B PB; Perco, Paul P; Leierer, Johannes J; Kronbichler, Andreas A; Steger, Marion M; Schwendinger, Simon S; Zschocke, Johannes J; Mayer, Gert G; Jukic, Emina E
Publication Date: 2022-04

Variant appearance in text: TP53: 743G>A; Arg248Gln
PubMed Link: 35497780
Variant Present in the following documents:
  • mmc1.pdf
View BVdb publication page



p53 and Zinc: A Malleable Relationship.

Frontiers In Molecular Biosciences
Ha, Jeung-Hoi JH; Prela, Orjola O; Carpizo, Darren R DR; Loh, Stewart N SN
Publication Date: 2022

Variant appearance in text: p53: R248Q
PubMed Link: 35495631
Variant Present in the following documents:
  • fmolb-09-895887.pdf
View BVdb publication page



Targeting TP53-Mutated Acute Myeloid Leukemia: Research and Clinical Developments.

Oncotargets And Therapy
Granowicz, Eric M EM; Jonas, Brian A BA
Publication Date: 2022

Variant appearance in text: TP53: R248Q
PubMed Link: 35479302
Variant Present in the following documents:
  • ott-15-423.pdf
View BVdb publication page



Germline MBD4 deficiency causes a multi-tumor predisposition syndrome.

American Journal Of Human Genetics
Palles, Claire C; West, Hannah D HD; Chew, Edward E; Galavotti, Sara S; Flensburg, Christoffer C; Grolleman, Judith E JE; Jansen, Erik A M EAM; Curley, Helen H; Chegwidden, Laura L; Arbe-Barnes, Edward H EH; Lander, Nicola N; Truscott, Rebekah R; Pagan, Judith J; Bajel, Ashish A; Sherwood, Kitty K; Martin, Lynn L; Thomas, Huw H; Georgiou, Demetra D; Fostira, Florentia F; Goldberg, Yael Y; Adams, David J DJ; van der Biezen, Simone A M SAM; Christie, Michael M; Clendenning, Mark M; Thomas, Laura E LE; Deltas, Constantinos C; Dimovski, Aleksandar J AJ; Dymerska, Dagmara D; Lubinski, Jan J; Mahmood, Khalid K; van der Post, Rachel S RS; Sanders, Mathijs M; Weitz, Jürgen J; Taylor, Jenny C JC; Turnbull, Clare C; Vreede, Lilian L; van Wezel, Tom T; Whalley, Celina C; Arnedo-Pac, Claudia C; Caravagna, Giulio G; Cross, William W; Chubb, Daniel D; Frangou, Anna A; Gruber, Andreas J AJ; Kinnersley, Ben B; Noyvert, Boris B; Church, David D; Graham, Trevor T; Houlston, Richard R; Lopez-Bigas, Nuria N; Sottoriva, Andrea A; Wedge, David D; , ; , ; , ; Jenkins, Mark A MA; Kuiper, Roland P RP; Roberts, Andrew W AW; Cheadle, Jeremy P JP; Ligtenberg, Marjolijn J L MJL; Hoogerbrugge, Nicoline N; Koelzer, Viktor H VH; Rivas, Andres Dacal AD; Winship, Ingrid M IM; Ponte, Clara Ruiz CR; Buchanan, Daniel D DD; Power, Derek G DG; Green, Andrew A; Tomlinson, Ian P M IPM; Sampson, Julian R JR; Majewski, Ian J IJ; de Voer, Richarda M RM
Publication Date: 2022-04-20

Variant appearance in text: TP53: 743G>A; Arg248Gln
PubMed Link: 35460607
Variant Present in the following documents:
  • mmc2.xlsx
View BVdb publication page



Advanced Strategies for Therapeutic Targeting of Wild-Type and Mutant p53 in Cancer.

Biomolecules
Zhang, Shengliang S; Carlsen, Lindsey L; Hernandez Borrero, Liz L; Seyhan, Attila A AA; Tian, Xiaobing X; El-Deiry, Wafik S WS
Publication Date: 2022-04-06

Variant appearance in text: p53: R248Q
PubMed Link: 35454137
Variant Present in the following documents:
  • biomolecules-12-00548.pdf
View BVdb publication page



Integrated profiling of human pancreatic cancer organoids reveals chromatin accessibility features associated with drug sensitivity.

Nature Communications
Shi, Xiaohan X; Li, Yunguang Y; Yuan, Qiuyue Q; Tang, Shijie S; Guo, Shiwei S; Zhang, Yehan Y; He, Juan J; Zhang, Xiaoyu X; Han, Ming M; Liu, Zhuang Z; Zhu, Yiqin Y; Gao, Suizhi S; Wang, Huan H; Xu, Xiongfei X; Zheng, Kailian K; Jing, Wei W; Chen, Luonan L; Wang, Yong Y; Jin, Gang G; Gao, Dong D
Publication Date: 2022-04-21

Variant appearance in text: TP53: R248Q
PubMed Link: 35449156
Variant Present in the following documents:
  • 41467_2022_29857_MOESM5_ESM.xlsx
View BVdb publication page



5-Hydroxymethylcytosine (5hmC) at or near cancer mutation hot spots as potential targets for early cancer detection.

Bmc Research Notes
Lu, Michael J MJ; Lu, Yabin Y
Publication Date: 2022-04-21

Variant appearance in text: TP53: 743G>A; R248Q
PubMed Link: 35449110
Variant Present in the following documents:
  • 13104_2022_Article_6028.pdf
View BVdb publication page



Therapeutic synergy of Triptolide and MDM2 inhibitor against acute myeloid leukemia through modulation of p53-dependent and -independent pathways.

Experimental Hematology & Oncology
Chen, Qinwei Q; Deng, Suqi S; Deng, Manman M; Shi, Yuanfei Y; Zhong, Mengya M; Ding, Lihong L; Jiang, Yuelong Y; Zhou, Yong Y; Carter, Bing Z BZ; Xu, Bing B
Publication Date: 2022-04-16

Variant appearance in text: p53: R248Q
PubMed Link: 35429966
Variant Present in the following documents:
  • 40164_2022_Article_276.pdf
View BVdb publication page



PIM1 genetic alterations associated with distinct molecular profiles, phenotypes and drug responses in diffuse large B-cell lymphoma.

Clinical And Translational Medicine
Zhang, Huilai H; Lu, Yaxiao Y; Zhang, Tingting T; Guan, Qingpei Q; Wang, Xiaoxuan X; Guo, Yixian Y; Li, Lanfang L; Qiu, Lihua L; Qian, Zhengzi Z; Zhou, Shiyong S; Gong, Wenchen W; Meng, Bin B; Ren, Xiubao X; Wang, Xianhuo X
Publication Date: 2022-04

Variant appearance in text: TP53: R248Q
PubMed Link: 35415904
Variant Present in the following documents:
  • CTM2-12-e808-s003.xlsx
View BVdb publication page



Proof-of-Concept Pilot Study on Comprehensive Spatiotemporal Intra-Patient Heterogeneity for Colorectal Cancer With Liver Metastasis.

Frontiers In Oncology
Kyrochristos, Ioannis D ID; Glantzounis, Georgios K GK; Goussia, Anna A; Eliades, Alexia A; Achilleos, Achilleas A; Tsangaras, Kyriakos K; Hadjidemetriou, Irene I; Elpidorou, Marilena M; Ioannides, Marios M; Koumbaris, George G; Mitsis, Michail M; Patsalis, Philippos C PC; Roukos, Dimitrios D
Publication Date: 2022

Variant appearance in text: TP53: 743G>A
PubMed Link: 35402285
Variant Present in the following documents:
  • Table_1.xlsx
View BVdb publication page



Clinicopathologic and Genomic Features in Triple-Negative Breast Cancer Between Special and No-Special Morphologic Pattern.

Frontiers In Oncology
Li, Ying-Zi YZ; Chen, Bo B; Lin, Xiao-Yi XY; Zhang, Guo-Chun GC; Lai, Jian-Guo JG; Li, Cheukfai C; Lin, Jia-Li JL; Guo, Li-Ping LP; Xiao, Wei-Kai WK; Mok, Hsiaopei H; Ren, Chong-Yang CY; Wen, Ling-Zhu LZ; Cao, Fang-Rong FR; Lin, Xin X; Qi, Xiao-Fang XF; Liu, Yang Y; Liao, Ning N
Publication Date: 2022

Variant appearance in text: TP53: R248Q
PubMed Link: 35402236
Variant Present in the following documents:
  • fonc-12-830124.pdf
View BVdb publication page



Plasma Genotyping at the Time of Diagnostic Tissue Biopsy Decreases Time-to-Treatment in Patients With Advanced NSCLC-Results From a Prospective Pilot Study.

Jto Clinical And Research Reports
Thompson, Jeffrey C JC; Aggarwal, Charu C; Wong, Janeline J; Nimgaonkar, Vivek V; Hwang, Wei-Ting WT; Andronov, Michelle M; Dibardino, David M DM; Hutchinson, Christoph T CT; Ma, Kevin C KC; Lanfranco, Anthony A; Moon, Edmund E; Haas, Andrew R AR; Singh, Aditi P AP; Ciunci, Christine A CA; Marmarelis, Melina M; D'Avella, Christopher C; Cohen, Justine V JV; Bauml, Joshua M JM; Cohen, Roger B RB; Langer, Corey J CJ; Vachani, Anil A; Carpenter, Erica L EL
Publication Date: 2022-04

Variant appearance in text: TP53: R248Q
PubMed Link: 35392653
Variant Present in the following documents:
  • mmc3.xlsx
View BVdb publication page



Deciphering the Increased Prevalence of TP53 Mutations in Metastatic Prostate Cancer.

Cancer Informatics
Zhang, Wensheng W; Dong, Yan Y; Sartor, Oliver O; Zhang, Kun K
Publication Date: 2022

Variant appearance in text: TP53: 743G>A
PubMed Link: 35392296
Variant Present in the following documents:
  • 10.1177_11769351221087046.pdf
View BVdb publication page



Comprehensive Analysis of the Carcinogenic Process, Tumor Microenvironment, and Drug Response in HPV-Positive Cancers.

Frontiers In Oncology
Yu, Xiaorong X; Xu, Jiankai J; Xu, Dahua D; Bi, Xiaoman X; Wang, Hong H; Lu, Yanda Y; Cao, Meng M; Wang, Wenxiang W; Xu, Zhizhou Z; Zheng, Dehua D; Chen, Liyang L; Zhang, Xiaodian X; Zheng, Shaojiang S; Li, Kongning K
Publication Date: 2022

Variant appearance in text: TP53: R248Q
PubMed Link: 35392231
Variant Present in the following documents:
  • fonc-12-842060.pdf
View BVdb publication page



A molecular approach integrating genomic and DNA methylation profiling for tissue of origin identification in lung-specific cancer of unknown primary.

Journal Of Translational Medicine
Chen, Kaiyan K; Zhang, Fanrong F; Yu, Xiaoqing X; Huang, Zhiyu Z; Gong, Lei L; Xu, Yanjun Y; Li, Hui H; Yu, Sizhe S; Fan, Yun Y
Publication Date: 2022-04-05

Variant appearance in text: TP53: R248Q
PubMed Link: 35382836
Variant Present in the following documents:
  • 12967_2022_Article_3362.pdf
View BVdb publication page



Establishment and Characterization of Brain Cancer Primary Cell Cultures From Patients to Enable Phenotypic Screening for New Drugs.

Frontiers In Pharmacology
dePadua, Michelle M; Kulothungan, Preethi P; Lath, Rahul R; Prasad, Ravikanti R; Madamchetty, Kranthi K; Atmakuri, Shravya S; Ragamouni, Sravanthi S; Gandhari, Mukesh M; Khandrika, Lakshmipathi L; Jain, Jugnu J
Publication Date: 2022

Variant appearance in text: TP53: R248Q
PubMed Link: 35370679
Variant Present in the following documents:
  • fphar-13-778193.pdf
View BVdb publication page



TP53 R273C Mutation Is Associated With Poor Prognosis in LGG Patients.

Frontiers In Genetics
Zhang, Jian J; Liu, Minglu M; Fang, Yujie Y; Li, Jinlong J; Chen, Yin Y; Jiao, Shunchang S
Publication Date: 2022

Variant appearance in text: p53: R248Q
PubMed Link: 35368662
Variant Present in the following documents:
  • fgene-13-720651.pdf
View BVdb publication page



Mutant p53: it's not all one and the same.

Cell Death And Differentiation
Kennedy, Margaret C MC; Lowe, Scott W SW
Publication Date: 2022-03-31

Variant appearance in text: p53: R248Q
PubMed Link: 35361963
Variant Present in the following documents:
  • 41418_2022_Article_989.pdf
View BVdb publication page



Distinct genomic landscape of Chinese pediatric acute myeloid leukemia impacts clinical risk classification.

Nature Communications
Liu, Ting T; Rao, Jianan J; Hu, Wenting W; Cui, Bowen B; Cai, Jiaoyang J; Liu, Yuhan Y; Sun, Huiying H; Chen, Xiaoxiao X; Tang, Yanjing Y; Chen, Jing J; Wang, Xiang X; Wang, Han H; Qian, Wubin W; Mao, Binchen B; Guo, Sheng S; Wang, Ronghua R; Liu, Yu Y; Shen, Shuhong S
Publication Date: 2022-03-28

Variant appearance in text: TP53: R248Q
PubMed Link: 35347147
Variant Present in the following documents:
  • 41467_2022_29336_MOESM8_ESM.xlsx
View BVdb publication page



Single-cell transcriptomic analysis suggests two molecularly subtypes of intrahepatic cholangiocarcinoma.

Nature Communications
Song, Guohe G; Shi, Yang Y; Meng, Lu L; Ma, Jiaqiang J; Huang, Siyuan S; Zhang, Juan J; Wu, Yingcheng Y; Li, Jiaxin J; Lin, Youpei Y; Yang, Shuaixi S; Rao, Dongning D; Cheng, Yifei Y; Lin, Jian J; Ji, Shuyi S; Liu, Yuming Y; Jiang, Shan S; Wang, Xiaoliang X; Zhang, Shu S; Ke, Aiwu A; Wang, Xiaoying X; Cao, Ya Y; Ji, Yuan Y; Zhou, Jian J; Fan, Jia J; Zhang, Xiaoming X; Xi, Ruibin R; Gao, Qiang Q
Publication Date: 2022-03-28

Variant appearance in text: TP53: 743G>A; R248Q
PubMed Link: 35347134
Variant Present in the following documents:
  • 41467_2022_29164_MOESM13_ESM.xlsx
View BVdb publication page



High-Throughput Drug Library Screening in Primary KMT2A-Rearranged Infant ALL Cells Favors the Identification of Drug Candidates That Activate P53 Signaling.

Biomedicines
Wander, Priscilla P; Arentsen-Peters, Susan T C J M STCJM; Vrenken, Kirsten S KS; Pinhanҫos, Sandra Mimoso SM; Koopmans, Bianca B; Dolman, M Emmy M MEM; Jones, Luke L; Garrido Castro, Patricia P; Schneider, Pauline P; Kerstjens, Mark M; Molenaar, Jan J JJ; Pieters, Rob R; Zwaan, Christian Michel CM; Stam, Ronald W RW
Publication Date: 2022-03-10

Variant appearance in text: p53: R248Q
PubMed Link: 35327440
Variant Present in the following documents:
  • biomedicines-10-00638.pdf
View BVdb publication page



Utilisation of semiconductor sequencing for the detection of predictive biomarkers in glioblastoma.

Plos One
Williams, Gareth G; Llewelyn, Alexander A; Thatcher, Robert R; Hardisty, Keeda-Marie KM; Loddo, Marco M
Publication Date: 2022

Variant appearance in text: TP53: 743G>A; Arg248Gln; rs11540652
PubMed Link: 35324914
Variant Present in the following documents:
  • pone.0245817.s005.pdf
View BVdb publication page



Response prediction and risk stratification of patients with rectal cancer after neoadjuvant therapy through an analysis of circulating tumour DNA.

Ebiomedicine
Liu, Wenyang W; Li, Yifei Y; Tang, Yuan Y; Song, Qianqian Q; Wang, Jingjing J; Li, Ning N; Chen, Silin S; Shi, Jinming J; Wang, Shulian S; Li, Yexiong Y; Jiao, Yuchen Y; Zeng, Yixin Y; Jin, Jing J
Publication Date: 2022-03-17

Variant appearance in text: TP53: 743G>A; rs11540652
PubMed Link: 35306340
Variant Present in the following documents:
  • mmc3.xlsx
View BVdb publication page



Evaluation of Targeted Next-Generation Sequencing for the Management of Patients Diagnosed with a Cancer of Unknown Primary.

The Oncologist
Fusco, Michael J MJ; Knepper, Todd C TC; Balliu, Juliana J; Del Cueto, Alex A; Laborde, Jose M JM; Hooda, Sharjeel M SM; Brohl, Andrew S AS; Bui, Marilyn M MM; Hicks, J Kevin JK
Publication Date: 2022-02-03

Variant appearance in text: TP53: R248Q
PubMed Link: 35305098
Variant Present in the following documents:
  • oyab014_suppl_supplementary_appendix_1.xlsx
View BVdb publication page



Dynamic changes in gene alterations during chemotherapy in metastatic castrate resistant prostate cancer.

Scientific Reports
Tan, Winston W; Zheng, Tiantian T; Wang, Amy A; Roacho, Joanna J; Thao, Seng S; Du, Pan P; Jia, Shidong S; Yu, Jianjun J; King, Bonnie L BL; Kohli, Manish M
Publication Date: 2022-03-18

Variant appearance in text: TP53: 743G>A; Arg248Gln
PubMed Link: 35304525
Variant Present in the following documents:
  • 41598_2022_8520_MOESM2_ESM.xlsx
View BVdb publication page



Multi-institutional Analysis of the Clinical and Genomic Characteristics of Black Patients with Metastatic Hormone-Sensitive Prostate Cancer.

The Oncologist
Freeman, Meredith N MN; Jang, Albert A; Zhu, Jason J; Sanati, Farhad F; Nandagopal, Lakshminarayanan L; Ravindranathan, Deepak D; Desai, Arpita A; Phone, Audrey A; Nussenzveig, Roberto R; Jaeger, Ellen E; Caputo, Sydney A SA; Koshkin, Vadim S VS; Swami, Umang U; Basu, Arnab A; Bilen, Mehmet A MA; Agarwal, Neeraj N; Sartor, Oliver O; Burgess, Earle F EF; Barata, Pedro C PC
Publication Date: 2022-03-11

Variant appearance in text: TP53: 743G>A; R248Q
PubMed Link: 35274720
Variant Present in the following documents:
  • oyab057.pdf
View BVdb publication page



Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications
Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L
Publication Date: 2022-03-10

Variant appearance in text: TP53: 743G>A; R248Q
PubMed Link: 35273153
Variant Present in the following documents:
  • 41467_2022_28840_MOESM5_ESM.xlsx
  • 41467_2022_28840_MOESM7_ESM.xlsx
  • 41467_2022_28840_MOESM4_ESM.xlsx
View BVdb publication page



Estrogen Receptor-Beta2 (ERβ2)-Mutant p53-FOXM1 Axis: A Novel Driver of Proliferation, Chemoresistance, and Disease Progression in High Grade Serous Ovarian Cancer (HGSOC).

Cancers
Oturkar, Chetan C CC; Gandhi, Nishant N; Rao, Pramod P; Eng, Kevin H KH; Miller, Austin A; Singh, Prashant K PK; Zsiros, Emese E; Odunsi, Kunle O KO; Das, Gokul M GM
Publication Date: 2022-02-22

Variant appearance in text: p53: R248Q
PubMed Link: 35267428
Variant Present in the following documents:
  • cancers-14-01120.pdf
View BVdb publication page



Detection of germline variants in Brazilian breast cancer patients using multigene panel testing.

Scientific Reports
Guindalini, Rodrigo Santa Cruz RSC; Viana, Danilo Vilela DV; Kitajima, João Paulo Fumio Whitaker JPFW; Rocha, Vinícius Marques VM; López, Rossana Verónica Mendoza RVM; Zheng, Yonglan Y; Freitas, Érika É; Monteiro, Fabiola Paoli Mendes FPM; Valim, André A; Schlesinger, David D; Kok, Fernando F; Olopade, Olufunmilayo I OI; Folgueira, Maria Aparecida Azevedo Koike MAAK
Publication Date: 2022-03-09

Variant appearance in text: TP53: 743G>A; Arg248Gln
PubMed Link: 35264596
Variant Present in the following documents:
  • 41598_2022_Article_7383.pdf
  • 41598_2022_7383_MOESM2_ESM.xlsx
View BVdb publication page



Pleomorphic rhabdomyosarcoma in a young adult harboring a novel germline MSH2 variant.

Human Genome Variation
Tomida, Akimasa A; Chiyonobu, Tomohiro T; Tokuda, Shinsaku S; Miyachi, Mitsuru M; Murashima, Kyoko K; Hirata, Makoto M; Nakagawa, Masanori M; Iehara, Tomoko T; Kuroda, Junya J; Takayama, Koichi K
Publication Date: 2022-03-08

Variant appearance in text: TP53: R248Q
PubMed Link: 35260566
Variant Present in the following documents:
  • 41439_2022_Article_185.pdf
View BVdb publication page



Rapid recruitment of p53 to DNA damage sites directs DNA repair choice and integrity.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Wang, Yu-Hsiu YH; Ho, Teresa L F TLF; Hariharan, Anushya A; Goh, Hui Chin HC; Wong, Yao Liang YL; Verkaik, Nicole S NS; Lee, May Yin MY; Tam, Wai Leong WL; van Gent, Dik C DC; Venkitaraman, Ashok R AR; Sheetz, Michael P MP; Lane, David P DP
Publication Date: 2022-03-08

Variant appearance in text: p53: R248Q
PubMed Link: 35235448
Variant Present in the following documents:
  • pnas.2113233119.sapp.pdf
  • pnas.202113233.pdf
View BVdb publication page



Glucose Influences the Response of Glioblastoma Cells to Temozolomide and Dexamethasone.

Cancer Control : Journal Of The Moffitt Cancer Center
Bielecka-Wajdman, Anna M AM; Ludyga, Tomasz T; Smyk, Daria D; Smyk, Wojciech W; Mularska, Magdalena M; Świderek, Patrycja P; Majewski, Wojciech W; Mullins, Christina Susanne CS; Linnebacher, Michael M; Obuchowicz, Ewa E
Publication Date: 2022

Variant appearance in text: TP53: R248Q
PubMed Link: 35225010
Variant Present in the following documents:
  • sj-pdf-1-ccx-10.1177_10732748221075468.pdf
View BVdb publication page



The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer
Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J
Publication Date: 2022-02

Variant appearance in text: TP53: Arg248Gln
PubMed Link: 35221333
Variant Present in the following documents:
  • 43018_2022_332_MOESM3_ESM.xlsx
View BVdb publication page



Association between germline pathogenic variants and breast cancer risk in Japanese women: the HERPACC study.

Cancer Science
Kasugai, Yumiko Y; Kohmoto, Tomohiro T; Taniyama, Yukari Y; Koyanagi, Yuriko N YN; Usui, Yoshiaki Y; Iwase, Madoka M; Oze, Isao I; Yamaguchi, Rui R; Ito, Hidemi H; Imoto, Issei I; Matsuo, Keitaro K
Publication Date: 2022-02-25

Variant appearance in text: TP53: 743G>A; R248Q; rs11540652
PubMed Link: 35218119
Variant Present in the following documents:
  • CAS-113-1451-s002.xlsx
View BVdb publication page



Effective targeting of breast cancer stem cells by combined inhibition of Sam68 and Rad51.

Oncogene
Turdo, Alice A; Gaggianesi, Miriam M; Di Franco, Simone S; Veschi, Veronica V; D'Accardo, Caterina C; Porcelli, Gaetana G; Lo Iacono, Melania M; Pillitteri, Irene I; Verona, Francesco F; Militello, Gabriella G; Zippo, Alessio A; Poli, Vittoria V; Fagnocchi, Luca L; Beyes, Sven S; Stella, Stefania S; Lattanzio, Rossano R; Faldetta, Naida N; Lentini, Vincenzo L VL; Porcasi, Rossana R; Pistone, Giuseppe G; Bongiorno, Maria Rita MR; Stassi, Giorgio G; De Maria, Ruggero R; Todaro, Matilde M
Publication Date: 2022-02-25

Variant appearance in text: TP53: R248Q
PubMed Link: 35217791
Variant Present in the following documents:
  • 41388_2022_Article_2239.pdf
View BVdb publication page



The metabolism of cells regulates their sensitivity to NK cells depending on p53 status.

Scientific Reports
Belkahla, Sana S; Brualla, Joaquin Marco JM; Fayd'herbe de Maudave, Alexis A; Falvo, Paolo P; Allende-Vega, Nerea N; Constantinides, Michael M; Khan, Abrar Ul Haq AUH; Coenon, Lois L; Alexia, Catherine C; Mitola, Giulia G; Massa, Paul P; Orecchioni, Stefania S; Bertolini, Francesco F; Mnif, Wissem W; Hernandez, Javier J; Anel, Alberto A; Villalba, Martin M
Publication Date: 2022-02-25

Variant appearance in text: p53: R248Q
PubMed Link: 35217717
Variant Present in the following documents:
  • 41598_2022_Article_7281.pdf
View BVdb publication page



p53 Signaling on Microenvironment and Its Contribution to Tissue Chemoresistance.

Membranes
Souza, Leonel Cardozo de Menezes E LCME; Faletti, Anderson A; Veríssimo, Carla Pires CP; Stelling, Mariana Paranhos MP; Borges, Helena Lobo HL
Publication Date: 2022-02-09

Variant appearance in text: p53: R248Q
PubMed Link: 35207121
Variant Present in the following documents:
  • membranes-12-00202.pdf
View BVdb publication page



The therapeutic potential of RNA Polymerase I transcription inhibitor, CX-5461, in uterine leiomyosarcoma.

Investigational New Drugs
Kang, Chang-Won CW; Hannan, Katherine M KM; Blackburn, Anneke C AC; Loh, Amos H P AHP; Hong, Kuick Chik KC; Yuan, Goh Jian GJ; Hein, Nadine N; Drygin, Denis D; Hannan, Ross D RD; Coupland, Lucy A LA
Publication Date: 2022-02-24

Variant appearance in text: TP53: R248Q
PubMed Link: 35201535
Variant Present in the following documents:
  • 10637_2022_Article_1222.pdf
View BVdb publication page



Genome-wide aneuploidy detected by mFast-SeqS in circulating cell-free DNA is associated with poor response to pembrolizumab in patients with advanced urothelial cancer.

Molecular Oncology
Mendelaar, Pauline A J PAJ; Robbrecht, Debbie D; Rijnders, Maud M; de Wit, Ronald R; de Weerd, Vanja V; Deger, Teoman T; Westgeest, Hans M HM; Aarts, Maureen J B MJB; Voortman, Jens J; Martens, John W M JWM; van der Veldt, Astrid A M AAM; Nakauma-González, J Alberto JA; Wilting, Saskia M SM; Lolkema, Martijn M
Publication Date: 2022-02-18

Variant appearance in text: TP53: 743G>A; R248Q
PubMed Link: 35181986
Variant Present in the following documents:
  • MOL2-16-2086.pdf
View BVdb publication page



Disease characterization in liquid biopsy from HER2-mutated, non-amplified metastatic breast cancer patients treated with neratinib.

Npj Breast Cancer
Shishido, Stephanie N SN; Masson, Rahul R; Xu, Liya L; Welter, Lisa L; Prabakar, Rishvanth Kaliappan RK; D' Souza, Anishka A; Spicer, Darcy D; Kang, Irene I; Jayachandran, Priya P; Hicks, James J; Lu, Janice J; Kuhn, Peter P
Publication Date: 2022-02-18

Variant appearance in text: TP53: R248Q
PubMed Link: 35181666
Variant Present in the following documents:
  • 41523_2022_Article_390.pdf
  • 41523_2022_390_MOESM1_ESM.pdf
View BVdb publication page



The genetic landscape of pancreatic head ductal adenocarcinoma in China and prognosis stratification.

Bmc Cancer
Yang, Yefan Y; Ding, Ying Y; Gong, Yuxi Y; Zhao, Sha S; Li, Mingna M; Li, Xiao X; Song, Guoxin G; Zhai, Boya B; Liu, Jin J; Shao, Yang Y; Zhu, Liuqing L; Pang, Jiaohui J; Ma, Yutong Y; Ou, Qiuxiang Q; Wu, Xue X; Zhang, Zhihong Z
Publication Date: 2022-02-18

Variant appearance in text: TP53: 743G>A; R248Q
PubMed Link: 35180847
Variant Present in the following documents:
  • 12885_2022_9279_MOESM3_ESM.xlsx
View BVdb publication page



ACTH-secreting pituitary carcinoma with TP53, NF1, ATRX and PTEN mutations Case report and review of the literature.

Endocrine
Sumislawski, Piotr P; Rotermund, Roman R; Klose, Silke S; Lautenbach, Anne A; Wefers, Annika K AK; Soltwedel, Celina C; Mohammadi, Behnam B; Jacobsen, Frank F; Mawrin, Christian C; Flitsch, Jörg J; Saeger, Wolfgang W
Publication Date: 2022-02-16

Variant appearance in text: TP53: 743G>A
PubMed Link: 35171439
Variant Present in the following documents:
  • 12020_2021_Article_2954.pdf
View BVdb publication page



RAS Mutation Conversion in Bevacizumab-Treated Metastatic Colorectal Cancer Patients: A Liquid Biopsy Based Study.

Cancers
Nicolazzo, Chiara C; Belardinilli, Francesca F; Vestri, Annarita A; Magri, Valentina V; De Renzi, Gianluigi G; De Meo, Michela M; Caponnetto, Salvatore S; Di Nicolantonio, Federica F; Cortesi, Enrico E; Giannini, Giuseppe G; Gazzaniga, Paola P
Publication Date: 2022-02-04

Variant appearance in text: TP53: 743G>A; R248Q
PubMed Link: 35159069
Variant Present in the following documents:
  • Main text
  • cancers-14-00802.pdf
View BVdb publication page



Targeting Oncogenic Pathways in the Era of Personalized Oncology: A Systemic Analysis Reveals Highly Mutated Signaling Pathways in Cancer Patients and Potential Therapeutic Targets.

Cancers
Karagiannakos, Alexandros A; Adamaki, Maria M; Tsintarakis, Antonis A; Vojtesek, Borek B; Fåhraeus, Robin R; Zoumpourlis, Vassilis V; Karakostis, Konstantinos K
Publication Date: 2022-01-28

Variant appearance in text: p53: R248Q
PubMed Link: 35158934
Variant Present in the following documents:
  • Main text
  • cancers-14-00664.pdf
View BVdb publication page



Intratumor genetic heterogeneity and clonal evolution to decode endometrial cancer progression.

Oncogene
Mota, Alba A; Oltra, Sara S SS; Selenica, Pier P; Moiola, Cristian P CP; Casas-Arozamena, Carlos C; López-Gil, Carlos C; Diaz, Eva E; Gatius, Sonia S; Ruiz-Miro, María M; Calvo, Ana A; Rojo-Sebastián, Alejandro A; Hurtado, Pablo P; Piñeiro, Roberto R; Colas, Eva E; Gil-Moreno, Antonio A; Reis-Filho, Jorge S JS; Muinelo-Romay, Laura L; Abal, Miguel M; Matias-Guiu, Xavier X; Weigelt, Britta B; Moreno-Bueno, Gema G
Publication Date: 2022-02-10

Variant appearance in text: TP53: R248Q
PubMed Link: 35145232
Variant Present in the following documents:
  • 41388_2022_2221_MOESM3_ESM.xlsx
View BVdb publication page



Acquired somatic variants in inherited myeloid malignancies.

Leukemia
Armes, Hannah H; Rio-Machin, Ana A; Krizsán, Szilvia S; Bödör, Csaba C; Kaya, Fadimana F; Bewicke-Copley, Findlay F; Alnajar, Jenna J; Walne, Amanda A; Péterffy, Borbála B; Tummala, Hemanth H; Rouault-Pierre, Kevin K; Dokal, Inderjeet I; Vulliamy, Tom T; Fitzgibbon, Jude J
Publication Date: 2022-02-09

Variant appearance in text: TP53: R248Q
PubMed Link: 35140362
Variant Present in the following documents:
  • 41375_2022_1515_MOESM4_ESM.xlsx
View BVdb publication page



The Mutational Landscape of Early-Onset Breast Cancer: A Next-Generation Sequencing Analysis.

Frontiers In Oncology
Andrikopoulou, Angeliki A; Chatzinikolaou, Spyridoula S; Kyriopoulos, Ilias I; Bletsa, Garyfalia G; Kaparelou, Maria M; Liontos, Michalis M; Dimopoulos, Meletios-Athanasios MA; Zagouri, Flora F
Publication Date: 2021

Variant appearance in text: TP53: 743G>A; Arg248Gln; rs11540652
PubMed Link: 35127508
Variant Present in the following documents:
  • Main text
  • fonc-11-797505.pdf
View BVdb publication page



Clinicopathological aspects of V-Raf murine sarcoma viral oncogene homolog B1 (BRAF) mutated non-small cell lung carcinoma in an Indian cohort: is there a difference?

International Journal Of Molecular Epidemiology And Genetics
Batra, Ullas U; Nathany, Shrinidhi S; Sharma, Mansi M; Mattoo, Sakshi S; Mehta, Anurag A; Jose, Joslia T JT
Publication Date: 2021

Variant appearance in text: TP53: Arg248Gln
PubMed Link: 35126834
Variant Present in the following documents:
  • Main text
View BVdb publication page



ROCK1 mechano-signaling dependency of human malignancies driven by TEAD/YAP activation.

Nature Communications
Esposito, Davide D; Pant, Ila I; Shen, Yao Y; Qiao, Rui F RF; Yang, Xiaobao X; Bai, Yiyang Y; Jin, Jian J; Poulikakos, Poulikos I PI; Aaronson, Stuart A SA
Publication Date: 2022-02-04

Variant appearance in text: p53: R248Q
PubMed Link: 35121738
Variant Present in the following documents:
  • Main text
  • 41467_2022_Article_28319.pdf
View BVdb publication page



Somatic Mutation Profiles Revealed by Next Generation Sequencing (NGS) in 39 Chinese Hepatocellular Carcinoma Patients.

Frontiers In Molecular Biosciences
Ke, Lixin L; Shen, Jianming J; Feng, Jikun J; Chen, Jialin J; Shen, Shunli S; Li, Shaoqiang S; Kuang, Ming M; Liang, Lijian L; Lu, Cuncun C; Li, Dongming D; He, Qiang Q; Peng, Baogang B; Hua, Yunpeng Y
Publication Date: 2021

Variant appearance in text: rs11540652
PubMed Link: 35118119
Variant Present in the following documents:
  • Table6.xlsx
View BVdb publication page



Application of next-generation sequencing in resistance genes of neoadjuvant chemotherapy for esophageal cancer.

Translational Cancer Research
Liu, Jizhao J; Xing, Wenqun W; Tian, Qingnan Q; Li, Yin Y; Liu, Xianben X; Sun, Haibo H; Gao, Kun K; Chen, Xiankai X; Zheng, Yan Y
Publication Date: 2020-08

Variant appearance in text: TP53: 743G>A; Arg248Gln
PubMed Link: 35117847
Variant Present in the following documents:
  • Main text
  • tcr-09-08-4847.pdf
View BVdb publication page



Suppression of NSCLC A549 tumor growth by a mtDNA mutation-targeting pyrrole-imidazole polyamide-TPP and a senolytic drug.

Cancer Science
Tsuji, Kohei K; Kida, Yuki Y; Koshikawa, Nobuko N; Yamamoto, Seigi S; Shinozaki, Yoshinao Y; Watanabe, Takayoshi T; Lin, Jason J; Nagase, Hiroki H; Takenaga, Keizo K
Publication Date: 2022-02-02

Variant appearance in text: p53: 743G>A
PubMed Link: 35112436
Variant Present in the following documents:
  • CAS-113-1321.pdf
View BVdb publication page