Publications:

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Differential chromatin accessibility landscape of gain-of-function mutant p53 tumours.

Bmc Cancer

Dhaka, Bhavya B; Sabarinathan, Radhakrishnan R

Publication Date: 2021-06-05

Variant appearance in text: p53: R248E

PubMed Link: 34090364

Variant Present in the following documents:

• Main text
• 12885_2021_Article_8362.pdf

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Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples.

Journal Of Translational Medicine

Dallol, Ashraf A; Buhmeida, Abdelbaset A; Al-Ahwal, Mahmoud Shaheen MS; Al-Maghrabi, Jaudah J; Bajouh, Osama O; Al-Khayyat, Shadi S; Alam, Rania R; Abusanad, Atlal A; Turki, Rola R; Elaimi, Aisha A; Alhadrami, Hani A HA; Abuzenadah, Mohammed M; Banni, Huda H; Al-Qahtani, Mohammed H MH; Abuzenadah, Adel M AM

Publication Date: 2016-05-04

Variant appearance in text: TP53: Arg248Glu

PubMed Link: 27146902

Variant Present in the following documents:

• Main text
• 12967_2016_Article_878.pdf

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Validation and utilisation of high-coverage next-generation sequencing to deliver the pharmacological audit trail.

British Journal Of Cancer

Ong, M M; Carreira, S S; Goodall, J J; Mateo, J J; Figueiredo, I I; Rodrigues, D N DN; Perkins, G G; Seed, G G; Yap, T A TA; Attard, G G; de Bono, J S JS

Publication Date: 2014-08-26

Variant appearance in text: TP53: R248E

PubMed Link: 24983367

Variant Present in the following documents:

• Main text
• bjc2014350a.pdf

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Frequency of TP53 Mutations and its Impact on Drug Sensitivity in Acute Myeloid Leukemia?

Indian Journal Of Clinical Biochemistry : Ijcb

Shah, Ankur A; Seedhouse, Claire C

Publication Date: 2012-04

Variant appearance in text: TP53: R248E

PubMed Link: 23543587

Variant Present in the following documents:

• Main text

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Tumour selection advantage of non-dominant negative P53 mutations in homozygotic MDM2-SNP309 colorectal cancer cells.

Journal Of Medical Genetics

Alazzouzi, Hafid H; Suriano, Gianpaolo G; Guerra, Angel A; Plaja, Alberto A; Espín, Eloi E; Armengol, Manel M; Alhopuro, Pia P; Velho, Sergia S; Shinomura, Yasuhisa Y; González-Aguilera, Juan José JJ; Yamamoto, Hiroyuki H; Aaltonen, Lauri A LA; Moreno, Víctor V; Capellà, Gabriel G; Peinado, Miguel Angel MA; Seruca, Raquel R; Arango, Diego D; Schwartz, Simó S

Publication Date: 2007-01

Variant appearance in text: p53: Arg248Glu

PubMed Link: 16825434

Variant Present in the following documents:

• Main text

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Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53.

Molecular And Cellular Biology

Blanchette, Paola P; Cheng, Chi Ying CY; Yan, Qin Q; Ketner, Gary G; Ornelles, David A DA; Dobner, Thomas T; Conaway, Ronald C RC; Conaway, Joan Weliky JW; Branton, Philip E PE

Publication Date: 2004-11

Variant appearance in text: p53: R248E

PubMed Link: 15485928

Variant Present in the following documents:

• Main text

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Identification of three functions of the adenovirus e4orf6 protein that mediate p53 degradation by the E4orf6-E1B55K complex.

Journal Of Virology

Querido, E E; Morrison, M R MR; Chu-Pham-Dang, H H; Thirlwell, S W SW; Boivin, D D; Branton, P E PE; Morisson, M R MR

Publication Date: 2001-01

Variant appearance in text: p53: R248E

PubMed Link: 11134283

Variant Present in the following documents:

• Main text

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Two distinct activities contribute to the oncogenic potential of the adenovirus type 5 E4orf6 protein.

Journal Of Virology

Nevels, M M; Rubenwolf, S S; Spruss, T T; Wolf, H H; Dobner, T T

Publication Date: 2000-06

Variant appearance in text: p53: R248E

PubMed Link: 10799592

Variant Present in the following documents:

• Main text

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The nuclear export signal within the E4orf6 protein of adenovirus type 5 supports virus replication and cytoplasmic accumulation of viral mRNA.

Journal Of Virology

Weigel, S S; Dobbelstein, M M

Publication Date: 2000-01

Variant appearance in text: p53: R248E

PubMed Link: 10623738

Variant Present in the following documents:

• Main text

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