Publications:

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Genetic mutations in HER2-positive breast cancer: possible association with response to trastuzumab therapy.

Human Genomics

Zakaria, Nermine H NH; Hashad, Doaa D; Saied, Marwa H MH; Hegazy, Neamat N; Elkayal, Alyaa A; Tayae, Eman E

Publication Date: 2023-05-18

Variant appearance in text: TP53: Ser241Phe; rs28934573

PubMed Link: 37202799

Variant Present in the following documents:

• Main text
• 40246_2023_Article_493.pdf

View BVdb publication page

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Spatial transcriptomics reveal topological immune landscapes of Asian head and neck angiosarcoma.

Communications Biology

Loh, Jui Wan JW; Lee, Jing Yi JY; Lim, Abner Herbert AH; Guan, Peiyong P; Lim, Boon Yee BY; Kannan, Bavani B; Lee, Elizabeth Chun Yong ECY; Gu, Ning Xin NX; Ko, Tun Kiat TK; Ng, Cedric Chuan-Young CC; Lim, Jeffrey Chun Tatt JCT; Yeong, Joe J; Lim, Jing Quan JQ; Ong, Choon Kiat CK; Teh, Bin Tean BT; Chan, Jason Yongsheng JY

Publication Date: 2023-04-27

Variant appearance in text: TP53: 722C>T; S241F

PubMed Link: 37106027

Variant Present in the following documents:

• 42003_2023_4856_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Dynamic ctDNA Mutational Complexity in Patients with Melanoma Receiving Immunotherapy.

Molecular Diagnosis & Therapy

Fitzgerald, Sandra S; Blenkiron, Cherie C; Stephens, Rosalie R; Mathy, Jon A JA; Somers-Edgar, Tiffany T; Rolfe, Gill G; Martin, Richard R; Jackson, Christopher C; Eccles, Michael M; Robb, Tamsin T; Rodger, Euan E; Lawrence, Ben B; Guilford, Parry P; Lasham, Annette A; Print, Cristin G CG

Publication Date: 2023-04-26

Variant appearance in text: TP53: 722C>T; S241F

PubMed Link: 37099071

Variant Present in the following documents:

• 40291_2023_651_MOESM1_ESM.xlsx, sheet 2

View BVdb publication page

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Predicting response to enzalutamide and abiraterone in metastatic prostate cancer using whole-omics machine learning.

Nature Communications

de Jong, Anouk C AC; Danyi, Alexandra A; van Riet, Job J; de Wit, Ronald R; Sjöström, Martin M; Feng, Felix F; de Ridder, Jeroen J; Lolkema, Martijn P MP

Publication Date: 2023-04-08

Variant appearance in text: TP53: S241F; rs28934573

PubMed Link: 37031196

Variant Present in the following documents:

• 41467_2023_37647_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications

Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA

Publication Date: 2023-04-03

Variant appearance in text: TP53: S241f

PubMed Link: 37012232

Variant Present in the following documents:

• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 3
• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2

View BVdb publication page

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Precise pancreatic cancer therapy through targeted degradation of mutant p53 protein by cerium oxide nanoparticles.

Journal Of Nanobiotechnology

Zhang, Hao H; Zhang, Wang W; Hu, Bochuan B; Qin, Xiaohua X; Yi, Tianxiang T; Ye, Yayi Y; Huang, Xiaowan X; Song, Yang Y; Yang, Zhenyu Z; Qian, Jieying J; Zhang, Yunjiao Y

Publication Date: 2023-04-01

Variant appearance in text: p53: S241F

PubMed Link: 37005668

Variant Present in the following documents:

• Main text
• 12951_2023_Article_1867.pdf

View BVdb publication page

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Circulating Tumor DNA Monitoring Reveals Molecular Progression before Radiologic Progression in a Real-life Cohort of Patients with Advanced Non-small Cell Lung Cancer.

Cancer Research Communications

Frank, Malene S MS; Andersen, Christina S A CSA; Ahlborn, Lise B LB; Pallisgaard, Niels N; Bodtger, Uffe U; Gehl, Julie J

Publication Date: 2022-10

Variant appearance in text: TP53: 722C>T; S241F

PubMed Link: 36969747

Variant Present in the following documents:

• crc-22-0258-s07.pdf
• crc-22-0258-s08.xlsx, sheet 1
• crc-22-0258-s09.xlsx, sheet 2

View BVdb publication page

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Different impacts of TP53 mutations on cell cycle-related gene expression among cancer types.

Scientific Reports

Sasaki, Keiju K; Takahashi, Shin S; Ouchi, Kota K; Otsuki, Yasufumi Y; Wakayama, Shonosuke S; Ishioka, Chikashi C

Publication Date: 2023-03-24

Variant appearance in text: TP53: S241F

PubMed Link: 36964217

Variant Present in the following documents:

• 41598_2023_32092_MOESM1_ESM.xlsx, sheet 4

View BVdb publication page

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RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer.

Nature

Jbara, Amina A; Lin, Kuan-Ting KT; Stossel, Chani C; Siegfried, Zahava Z; Shqerat, Haya H; Amar-Schwartz, Adi A; Elyada, Ela E; Mogilevsky, Maxim M; Raitses-Gurevich, Maria M; Johnson, Jared L JL; Yaron, Tomer M TM; Ovadia, Ofek O; Jang, Gun Ho GH; Danan-Gotthold, Miri M; Cantley, Lewis C LC; Levanon, Erez Y EY; Gallinger, Steven S; Krainer, Adrian R AR; Golan, Talia T; Karni, Rotem R

Publication Date: 2023-03-22

Variant appearance in text: TP53: S241F

PubMed Link: 36949200

Variant Present in the following documents:

• 41586_2023_5820_MOESM4_ESM.xlsx, sheet 3

View BVdb publication page

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A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Jang, H Josh HJ; Hostetter, Galen G; MacFarlane, Alexander W AW; Madaj, Zachary Z; Ross, Eric A EA; Hinoue, Toshinori T; Kulchycki, Justin R JR; Burgos, Ryan S RS; Tafseer, Mahvish M; Alpaugh, R Katherine RK; Schwebel, Candice L CL; Kokate, Rutika R; Geynisman, Daniel M DM; Zibelman, Matthew R MR; Ghatalia, Pooja P; Nichols, Peter W PW; Chung, Woonbok W; Madzo, Jozef J; Hahn, Noah M NM; Quinn, David I DI; Issa, Jean-Pierre J JJ; Topper, Michael J MJ; Baylin, Stephen B SB; Shen, Hui H; Campbell, Kerry S KS; Jones, Peter A PA; Plimack, Elizabeth R ER

Publication Date: 2023-03-16

Variant appearance in text: TP53: S241F

PubMed Link: 36928921

Variant Present in the following documents:

• ccr-22-3642_supplementary_tables_1_suppts1.xlsx, sheet 3

View BVdb publication page

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Role of p53 in breast cancer progression: An insight into p53 targeted therapy.

Theranostics

Marvalim, Charlie C; Datta, Arpita A; Lee, Soo Chin SC

Publication Date: 2023

Variant appearance in text: p53: S241F

PubMed Link: 36923534

Variant Present in the following documents:

• Main text
• thnov13p1421.pdf

View BVdb publication page

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Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.

Cancer Research Communications

White, Jason A JA; Kaninjing, Ernest T ET; Adeniji, Kayode A KA; Jibrin, Paul P; Obafunwa, John O JO; Ogo, Chidiebere N CN; Mohammed, Faruk F; Popoola, Ademola A; Fatiregun, Omolara A OA; Oluwole, Olabode P OP; Karanam, Balasubramanyam B; Elhussin, Isra I; Ambs, Stefan S; Tang, Wei W; Davis, Melissa M; Polak, Paz P; Campbell, Moray J MJ; Brignole, Kathryn R KR; Rotimi, Solomon O SO; Dean-Colomb, Windy W; Odedina, Folake T FT; Martin, Damali N DN; Yates, Clayton C

Publication Date: 2022-09

Variant appearance in text: TP53: 722C>T; S241F; rs28934573

PubMed Link: 36922933

Variant Present in the following documents:

• crc-22-0136-s01.xlsx, sheet 3

View BVdb publication page

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Evaluation of AlphaFold structure-based protein stability prediction on missense variations in cancer.

Frontiers In Genetics

Keskin Karakoyun, Hilal H; Yüksel, Şirin K ŞK; Amanoglu, Ilayda I; Naserikhojasteh, Lara L; Yeşilyurt, Ahmet A; Yakıcıer, Cengiz C; Timuçin, Emel E; Akyerli, Cemaliye B CB

Publication Date: 2023

Variant appearance in text: TP53: S241F

PubMed Link: 36896237

Variant Present in the following documents:

• Table1.xlsx, sheet 1

View BVdb publication page

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USP35 promotes cell proliferation and chemotherapeutic resistance through stabilizing FUCA1 in colorectal cancer.

Oncogenesis

Xiao, Yi Y; Jiang, Xiaoyu X; Yin, Ke K; Miao, Tianshu T; Lu, Hanlin H; Wang, Wenqing W; Ma, Lijuan L; Zhao, Yinghui Y; Liu, Chunyan C; Qiao, Yun Y; Zhang, Pengju P

Publication Date: 2023-03-03

Variant appearance in text: p53: S241F

PubMed Link: 36864055

Variant Present in the following documents:

• Main text
• 41389_2023_Article_458.pdf

View BVdb publication page

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Adaptation to spindle assembly checkpoint inhibition through the selection of specific aneuploidies.

Genes & Development

Adell, Manuel Alonso Y MAY; Klockner, Tamara C TC; Höfler, Rudolf R; Wallner, Lea L; Schmid, Julia J; Markovic, Ana A; Martyniak, Anastasiia A; Campbell, Christopher S CS

Publication Date: 2023-03-01

Variant appearance in text: p53: S241F

PubMed Link: 36859339

Variant Present in the following documents:

• Main text
• 171.pdf

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: TP53: 722C>T; Ser241Phe

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Application of Genomic Sequencing to Refine Patient Stratification for Adjuvant Therapy in Renal Cell Carcinoma.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Vasudev, Naveen S NS; Scelo, Ghislaine G; Glennon, Kate I KI; Wilson, Michelle M; Letourneau, Louis L; Eveleigh, Robert R; Nourbehesht, Nazanin N; Arseneault, Madeleine M; Paccard, Antoine A; Egevad, Lars L; Viksna, Juris J; Celms, Edgars E; Jackson, Sharon M SM; Abedi-Ardekani, Behnoush B; Warren, Anne Y AY; Selby, Peter J PJ; Trainor, Sebastian S; Kimuli, Michael M; Cartledge, Jon J; Soomro, Naeem N; Adeyoju, Adebanji A; Patel, Poulam M PM; Wozniak, Magdalena B MB; Holcatova, Ivana I; Brisuda, Antonin A; Janout, Vladimir V; Chanudet, Estelle E; Zaridze, David D; Moukeria, Anush A; Shangina, Oxana O; Foretova, Lenka L; Navratilova, Marie M; Mates, Dana D; Jinga, Viorel V; Bogdanovic, Ljiljana L; Kovacevic, Bozidar B; Cambon-Thomsen, Anne A; Bourque, Guillaume G; Brazma, Alvis A; Tost, Jörg J; Brennan, Paul P; Lathrop, Mark M; Riazalhosseini, Yasser Y; Banks, Rosamonde E RE

Publication Date: 2023-02-23

Variant appearance in text: TP53: 722C>T; Ser241Phe; rs28934573

PubMed Link: 36815791

Variant Present in the following documents:

• ccr-22-1936_supplementary_table_s2_suppts2.xlsx, sheet 1

View BVdb publication page

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Clinical impact of TP53 disruption in chronic lymphocytic leukemia patients treated with ibrutinib: a campus CLL study.

Leukemia

Bomben, Riccardo R; Rossi, Francesca Maria FM; Vit, Filippo F; Bittolo, Tamara T; Zucchetto, Antonella A; Papotti, Robel R; Tissino, Erika E; Pozzo, Federico F; Degan, Massimo M; Polesel, Jerry J; Bulian, Pietro P; Marasca, Roberto R; Reda, Gianluigi G; Laurenti, Luca L; Olivieri, Jacopo J; Chiarenza, Annalisa A; Laureana, Roberta R; Postorino, Massimiliano M; Del Principe, Maria Ilaria MI; Cuneo, Antonio A; Gentile, Massimo M; Morabito, Fortunato F; Fronza, Gilberto G; Tafuri, Agostino A; Zaja, Francesco F; Foà, Robin R; Di Raimondo, Francesco F; Del Poeta, Giovanni G; Gattei, Valter V

Publication Date: 2023-02-18

Variant appearance in text: TP53: 722C>T; S241F

PubMed Link: 36807650

Variant Present in the following documents:

• 41375_2023_1845_MOESM1_ESM.pdf

View BVdb publication page

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RNA Sequencing Identifies Frequent Mitogen Activated Protein Kinase-Associated Fusion Genes in Intraductal Tubulopapillary Neoplasms of the Pancreas.

Gastroenterology

Lee, Jae W JW; Hruban, Ralph H RH; Brosens, Lodewijk A A LAA; Condello, Vincenzo V; , ; Nikiforova, Marina N MN; Singhi, Aatur D AD

Publication Date: 2023-02-17

Variant appearance in text: TP53: S241F

PubMed Link: 36801389

Variant Present in the following documents:

• nihms-1903203.pdf

View BVdb publication page

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Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.

Nature Communications

Hong, Lingzhi L; Aminu, Muhammad M; Li, Shenduo S; Lu, Xuetao X; Petranovic, Milena M; Saad, Maliazurina B MB; Chen, Pingjun P; Qin, Kang K; Varghese, Susan S; Rinsurongkawong, Waree W; Rinsurongkawong, Vadeerat V; Spelman, Amy A; Elamin, Yasir Y YY; Negrao, Marcelo V MV; Skoulidis, Ferdinandos F; Gay, Carl M CM; Cascone, Tina T; Gandhi, Saumil J SJ; Lin, Steven H SH; Lee, Percy P PP; Carter, Brett W BW; Wu, Carol C CC; Antonoff, Mara B MB; Sepesi, Boris B; Lewis, Jeff J; Gibbons, Don L DL; Vaporciyan, Ara A AA; Le, Xiuning X; Jack Lee, J J; Roy-Chowdhuri, Sinchita S; Routbort, Mark J MJ; Gainor, Justin F JF; Heymach, John V JV; Lou, Yanyan Y; Wu, Jia J; Zhang, Jianjun J; Vokes, Natalie I NI

Publication Date: 2023-02-08

Variant appearance in text: TP53: 722C>T; S241F

PubMed Link: 36755027

Variant Present in the following documents:

• 41467_2023_36328_MOESM7_ESM.xlsx, sheet 1
• 41467_2023_36328_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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FGF19 promotes cell autophagy and cisplatin chemoresistance by activating MAPK signaling in ovarian cancer.

Peerj

Zhu, Wei W; Huang, Meiyuan M; Thakur, Abhimanyu A; Yan, Yuanliang Y; Wu, Xiaoying X

Publication Date: 2023

Variant appearance in text: TP53: 722C>T; Ser241Phe; rs28934573

PubMed Link: 36751636

Variant Present in the following documents:

• peerj-11-14827-s010.xlsx, sheet 1

View BVdb publication page

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Genomic complexity predicts resistance to endocrine therapy and CDK4/6 inhibition in hormone receptor-positive (HR+)/HER2-negative metastatic breast cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Davis, Andrew A AA; Luo, Jingqin J; Zheng, Tiantian T; Dai, Chao C; Dong, Xiaoxi X; Tan, Lu L; Suresh, Rama R; Ademuyiwa, Foluso O FO; Rigden, Caron C; Rearden, Timothy P TP; Clifton, Katherine K; Weilbaecher, Katherine K; Frith, Ashley A; Tandra, Pavankumar K PK; Summa, Tracy T; Haas, Brittney B; Thomas, Shana S; Hernandez-Aya, Leonel F LF; Peterson, Lindsay L LL; Wang, Xiaohong X; Luo, Shujun J SJ; Zhou, Kemin K; Du, Pan P; Jia, Shidong S; King, Bonnie L BL; Krishnamurthy, Jairam J; Ma, Cynthia X CX

Publication Date: 2023-01-24

Variant appearance in text: TP53: 722C>T; Ser241Phe

PubMed Link: 36693175

Variant Present in the following documents:

• ccr-22-2177_supplementary_data_s1_suppds1.xlsx, sheet 3

View BVdb publication page

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The Challenges and Prospects of p53-Based Therapies in Ovarian Cancer.

Biomolecules

Wallis, Bryce B; Bowman, Katherine Redd KR; Lu, Phong P; Lim, Carol S CS

Publication Date: 2023-01-12

Variant appearance in text: p53: S241F

PubMed Link: 36671544

Variant Present in the following documents:

• Main text
• biomolecules-13-00159.pdf

View BVdb publication page

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Comprehensive ctDNA measurements improve prediction of clinical outcomes and enable dynamic tracking of disease progression in advanced pancreatic cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Lapin, Morten M; Edland, Karin H KH; Tjensvoll, Kjersti K; Oltedal, Satu S; Austdal, Marie M; Garresori, Herish H; Rozenholc, Yves Y; Gilje, Bjørnar B; Nordgård, Oddmund O

Publication Date: 2023-01-20

Variant appearance in text: TP53: S241F

PubMed Link: 36662807

Variant Present in the following documents:

• ccr-22-3526_supplemental_table_1_suppts1.xlsx, sheet 1

View BVdb publication page

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Immunogenomic analysis of human brain metastases reveals diverse immune landscapes across genetically distinct tumors.

Cell Reports. Medicine

Álvarez-Prado, Ángel F ÁF; Maas, Roeltje R RR; Soukup, Klara K; Klemm, Florian F; Kornete, Mara M; Krebs, Fanny S FS; Zoete, Vincent V; Berezowska, Sabina S; Brouland, Jean-Philippe JP; Hottinger, Andreas F AF; Daniel, Roy T RT; Hegi, Monika E ME; Joyce, Johanna A JA

Publication Date: 2023-01-17

Variant appearance in text: TP53: S241F

PubMed Link: 36652909

Variant Present in the following documents:

• mmc4.xlsx, sheet 8

View BVdb publication page

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Structural basis of bacterial effector protein azurin targeting tumor suppressor p53 and inhibiting its ubiquitination.

Communications Biology

Hu, Jianjian J; Jiang, Wenxue W; Zuo, Jiaqi J; Shi, Dujuan D; Chen, Xiaoqi X; Yang, Xiao X; Zhang, Wenhui W; Ma, Lixin L; Liu, Zhu Z; Xing, Qiong Q

Publication Date: 2023-01-17

Variant appearance in text: p53: S241F

PubMed Link: 36650277

Variant Present in the following documents:

• Main text
• 42003_2023_Article_4458.pdf
• 42003_2023_4458_MOESM2_ESM.pdf

View BVdb publication page

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Clinical utility of Todai OncoPanel in the setting of approved comprehensive cancer genomic profiling tests in Japan.

Cancer Science

Kage, Hidenori H; Shinozaki-Ushiku, Aya A; Ishigaki, Kazunaga K; Sato, Yusuke Y; Tanabe, Masahiko M; Tanaka, Shota S; Tanikawa, Michihiro M; Watanabe, Kousuke K; Kato, Shingo S; Akagi, Kiwamu K; Uchino, Keita K; Mitani, Kinuko K; Takahashi, Shunji S; Miura, Yuji Y; Ikeda, Sadakatsu S; Kojima, Yasushi Y; Watanabe, Kiyotaka K; Mochizuki, Hitoshi H; Yamaguchi, Hironori H; Kawazoe, Yoshimasa Y; Kashiwabara, Kosuke K; Kohsaka, Shinji S; Tatsuno, Kenji K; Ushiku, Tetsuo T; Ohe, Kazuhiko K; Yatomi, Yutaka Y; Seto, Yasuyuki Y; Aburatani, Hiroyuki H; Mano, Hiroyuki H; Miyagawa, Kiyoshi K; Oda, Katsutoshi K

Publication Date: 2023-01-05

Variant appearance in text: TP53: 722C>T; S241F

PubMed Link: 36601953

Variant Present in the following documents:

• CAS-114-1710-s001.xlsx, sheet 1

View BVdb publication page

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ESR1 gene amplification and MAP3K mutations are selected during adjuvant endocrine therapies in relapsing Hormone Receptor-positive, HER2-negative breast cancer (HR+ HER2- BC).

Plos Genetics

Ferrando, Lorenzo L; Vingiani, Andrea A; Garuti, Anna A; Vernieri, Claudio C; Belfiore, Antonino A; Agnelli, Luca L; Dagrada, Gianpaolo G; Ivanoiu, Diana D; Bonizzi, Giuseppina G; Munzone, Elisabetta E; Lippolis, Luana L; Dameri, Martina M; Ravera, Francesco F; Colleoni, Marco M; Viale, Giuseppe G; Magnani, Luca L; Ballestrero, Alberto A; Zoppoli, Gabriele G; Pruneri, Giancarlo G

Publication Date: 2023-01-03

Variant appearance in text: rs28934573

PubMed Link: 36595552

Variant Present in the following documents:

• pgen.1010563.s004.xlsx, sheet 1

View BVdb publication page

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Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis.

Nature Cancer

Garcia-Recio, Susana S; Hinoue, Toshinori T; Wheeler, Gregory L GL; Kelly, Benjamin J BJ; Garrido-Castro, Ana C AC; Pascual, Tomas T; De Cubas, Aguirre A AA; Xia, Youli Y; Felsheim, Brooke M BM; McClure, Marni B MB; Rajkovic, Andrei A; Karaesmen, Ezgi E; Smith, Markia A MA; Fan, Cheng C; Ericsson, Paula I Gonzalez PIG; Sanders, Melinda E ME; Creighton, Chad J CJ; Bowen, Jay J; Leraas, Kristen K; Burns, Robyn T RT; Coppens, Sara S; Wheless, Amy A; Rezk, Salma S; Garrett, Amy L AL; Parker, Joel S JS; Foy, Kelly K KK; Shen, Hui H; Park, Ben H BH; Krop, Ian I; Anders, Carey C; Gastier-Foster, Julie J; Rimawi, Mothaffar F MF; Nanda, Rita R; Lin, Nancy U NU; Isaacs, Claudine C; Marcom, P Kelly PK; Storniolo, Anna Maria AM; Couch, Fergus J FJ; Chandran, Uma U; Davis, Michael M; Silverstein, Jonathan J; Ropelewski, Alexander A; Liu, Minetta C MC; Hilsenbeck, Susan G SG; Norton, Larry L; Richardson, Andrea L AL; Symmans, W Fraser WF; Wolff, Antonio C AC; Davidson, Nancy E NE; Carey, Lisa A LA; Lee, Adrian V AV; Balko, Justin M JM; Hoadley, Katherine A KA; Laird, Peter W PW; Mardis, Elaine R ER; King, Tari A TA; , ; Perou, Charles M CM

Publication Date: 2022-12-30

Variant appearance in text: TP53: S241F

PubMed Link: 36585450

Variant Present in the following documents:

• 43018_2022_Article_491.pdf

View BVdb publication page

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Benign Neurofibroma/Schwannoma Hybrid Peripheral Nerve Sheath Tumor of the Ulnar Nerve Harboring a Metastatic Papillary Thyroid Carcinoma Deposit: A Case Report of Tumor-to-Tumor Metastasis.

Case Reports In Pathology

Colazo, Juan M JM; Perez, Alexander N AN; Judice, Anthony D AD; Quirion, Julia J; Prieto-Granada, Carlos N CN; Holt, Ginger E GE

Publication Date: 2022

Variant appearance in text: TP53: 722C>T; S241F

PubMed Link: 36570791

Variant Present in the following documents:

• CRIPA2022-9038222.pdf

View BVdb publication page

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: TP53: S241F

PubMed Link: 36561320

Variant Present in the following documents:

• Main text
• Table3.xlsx, sheet 1
• Table2.xlsx, sheet 7
• fgene-13-1071352.pdf

View BVdb publication page

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Metastatic colorectal cancer treatment response evaluation by ultra-deep sequencing of cell-free DNA and matched white blood cells.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

van 't Erve, Iris I; Medina, Jamie E JE; Leal, Alessandro A; Papp, Eniko E; Phallen, Jillian J; Adleff, Vilmos V; Chiao, Elaine Jiayuee EJ; Arun, Adith S AS; Bolhuis, Karen K; Simmons, John K JK; Karandikar, Aanavi A; Valkenburg, Kenneth C KC; Sausen, Mark M; Angiuoli, Samuel V SV; Scharpf, Robert B RB; Punt, Cornelis J A CJA; Meijer, Gerrit A GA; Velculescu, Victor E VE; Fijneman, Remond J A RJA

Publication Date: 2022-12-19

Variant appearance in text: TP53: S241F

PubMed Link: 36534496

Variant Present in the following documents:

• ccr-22-2538_supplementary_tables_s1-s15_suppts1-ts15.xlsx, sheet 7

View BVdb publication page

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Synthetical lethality of Werner helicase and mismatch repair deficiency is mediated by p53 and PUMA in colon cancer.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Hao, Suisui S; Tong, Jingshan J; Jha, Anupma A; Risnik, Denise D; Lizardo, Darleny D; Lu, Xinyan X; Goel, Ajay A; Opresko, Patricia L PL; Yu, Jian J; Zhang, Lin L

Publication Date: 2022-12-20

Variant appearance in text: p53: S241F

PubMed Link: 36508676

Variant Present in the following documents:

• pnas.202211775.pdf

View BVdb publication page

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An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology

Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y

Publication Date: 2022

Variant appearance in text: TP53: 722C>T; S241F

PubMed Link: 36505399

Variant Present in the following documents:

• Table_2.xlsx, sheet 2
• Table_2.xlsx, sheet 3

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Efficacy and safety analyses of epidermal growth factor receptor tyrosine kinase inhibitors combined with chemotherapy in the treatment of advanced non-small-cell lung cancer with an EGFR/TP53 co-mutation.

Bmc Cancer

Shang, Kai K; Huang, Hongxiang H; Xu, Yongkang Y; Liu, Yangyang Y; Lu, Zhihui Z; Chen, Li L

Publication Date: 2022-12-12

Variant appearance in text: TP53: S241F

PubMed Link: 36503478

Variant Present in the following documents:

• Main text
• 12885_2022_Article_10391.pdf

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Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer.

Nature Communications

Sivakumar, Smruthy S; Jin, Dexter X DX; Tukachinsky, Hanna H; Murugesan, Karthikeyan K; McGregor, Kimberly K; Danziger, Natalie N; Pavlick, Dean D; Gjoerup, Ole O; Ross, Jeffrey S JS; Harmon, Robert R; Chung, Jon J; Decker, Brennan B; Dennis, Lucas L; Frampton, Garrett M GM; Molinero, Luciana L; Oesterreich, Steffi S; Venstrom, Jeffrey M JM; Oxnard, Geoffrey R GR; Hegde, Priti S PS; Sokol, Ethan S ES

Publication Date: 2022-12-05

Variant appearance in text: TP53: S241F

PubMed Link: 36470901

Variant Present in the following documents:

• 41467_2022_35245_MOESM4_ESM.xlsx, sheet 17

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Validation and Clinical Application of ONCOaccuPanel for Targeted Next-Generation Sequencing of Solid Tumors.

Cancer Research And Treatment

Kim, Moonsik M; Lee, Changseon C; Hong, Juyeon J; Kim, Juhee J; Jeong, Ji Yun JY; Park, Nora Jee-Young NJ; Kim, Ji-Eun JE; Park, Ji Young JY

Publication Date: 2022-11-25

Variant appearance in text: TP53: S241F

PubMed Link: 36470260

Variant Present in the following documents:

• crt-2022-891-Supplementary-Table-2.pdf

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A sex-informed approach to improve the personalised decision making process in myelodysplastic syndromes: a multicentre, observational cohort study.

The Lancet. Haematology

,

Publication Date: 2022-11-24

Variant appearance in text: TP53: 722C>T

PubMed Link: 36436542

Variant Present in the following documents:

• mmc2.xlsx, sheet 1

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Molecular diagnosis of pancreatobiliary tract cancer by detecting mutations and methylation changes in bile samples.

Eclinicalmedicine

He, Shun S; Zeng, Fanxin F; Yin, Huihui H; Wang, Pei P; Bai, Yinlei Y; Song, Qianqian Q; Chu, Jiangtao J; Huang, Zhen Z; Liu, Yumeng Y; Liu, Hong H; Chen, Qichen Q; Liu, Li L; Zhou, Jun J; Hu, Hanjie H; Li, Xingchen X; Li, Tengyan T; Wang, Guiqi G; Cai, Jianqiang J; Jiao, Yuchen Y; Zhao, Hong H

Publication Date: 2023-01

Variant appearance in text: TP53: 722C>T; Ser241Phe

PubMed Link: 36425869

Variant Present in the following documents:

• mmc1.xlsx, sheet 4

View BVdb publication page

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Downregulation of protein kinase C gamma reduces epithelial property and enhances malignant phenotypes in colorectal cancer cells.

Iscience

Satow, Reiko R; Suzuki, Yudai Y; Asada, Shinobu S; Ota, Sae S; Idogawa, Masashi M; Kubota, Shiori S; Ikeo, Noi N; Yoneda, Atsuko A; Fukami, Kiyoko K

Publication Date: 2022-12-22

Variant appearance in text: TP53: S241F

PubMed Link: 36404918

Variant Present in the following documents:

• mmc1.pdf

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: TP53: S241F

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Gain of Function (GOF) Mutant p53 in Cancer-Current Therapeutic Approaches.

International Journal Of Molecular Sciences

Roszkowska, Katarzyna A KA; Piecuch, Aleksandra A; Sady, Maria M; Gajewski, Zdzisław Z; Flis, Sylwia S

Publication Date: 2022-10-31

Variant appearance in text: p53: S241F

PubMed Link: 36362074

Variant Present in the following documents:

• Main text

View BVdb publication page

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Hepcidin Upregulation in Colorectal Cancer Associates with Accumulation of Regulatory Macrophages and Epithelial-Mesenchymal Transition and Correlates with Progression of the Disease.

Cancers

Di Grazia, Antonio A; Di Fusco, Davide D; Franzè, Eleonora E; Colella, Marco M; Strimpakos, Georgios G; Salvatori, Silvia S; Formica, Vincenzo V; Laudisi, Federica F; Maresca, Claudia C; Colantoni, Alfredo A; Ortenzi, Angela A; Stolfi, Carmine C; Monteleone, Ivan I; Monteleone, Giovanni G

Publication Date: 2022-10-27

Variant appearance in text: TP53: S241F

PubMed Link: 36358713

Variant Present in the following documents:

• Main text
• cancers-14-05294.pdf

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Recurrent missense variants in clonal hematopoiesis-related genes present in the general population.

Clinical Genetics

Ariste, Olivier O; de la Grange, Pierre P; Veitia, Reiner A RA

Publication Date: 2022-11-10

Variant appearance in text: TP53: 722C>T; Ser241Phe; rs28934573

PubMed Link: 36353970

Variant Present in the following documents:

• CGE-103-247-s001.xlsx, sheet 1

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NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma.

Cell Reports

Ramakrishnan, Gopalakrishnan G; Parajuli, Parash P; Singh, Pura P; Friend, Creighton C; Hurwitz, Eric E; Prunier, Celine C; Razzaque, Mohammed S MS; Xu, Keli K; Atfi, Azeddine A

Publication Date: 2022-11-08

Variant appearance in text: TP53: S241F

PubMed Link: 36351408

Variant Present in the following documents:

• NIHMS1848910-supplement-2.xlsx, sheet 2
• NIHMS1848910-supplement-2.xlsx, sheet 3

View BVdb publication page

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Genomic landscape, immune characteristics and prognostic mutation signature of cervical cancer in China.

Bmc Medical Genomics

Liu, Jing J; Li, Zirong Z; Lu, Ting T; Pan, Junping J; Li, Li L; Song, Yanwen Y; Hu, Dan D; Zhuo, Yanhong Y; Chen, Ying Y; Xu, Qin Q

Publication Date: 2022-11-04

Variant appearance in text: TP53: 722C>T; S241f

PubMed Link: 36333792

Variant Present in the following documents:

• 12920_2022_1376_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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USP7 regulates the ncPRC1 Polycomb axis to stimulate genomic H2AK119ub1 deposition uncoupled from H3K27me3.

Science Advances

Sijm, Ayestha A; Atlasi, Yaser Y; van der Knaap, Jan A JA; Wolf van der Meer, Joyce J; Chalkley, Gillian E GE; Bezstarosti, Karel K; Dekkers, Dick H W DHW; Doff, Wouter A S WAS; Ozgur, Zeliha Z; van IJcken, Wilfred F J WFJ; Demmers, Jeroen A A JAA; Verrijzer, C Peter CP

Publication Date: 2022-11-04

Variant appearance in text: p53: S241F

PubMed Link: 36332031

Variant Present in the following documents:

• Main text
• sciadv.abq7598.pdf

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Clinical and molecular characteristics of kinase domain duplications across diverse cancer types in the Chinese population.

Cancer Medicine

Lai, Xiaojing X; Yu, Ruoying R; Ou, Qiuxiang Q; Bao, Hua H; Wu, Xue X; Shao, Yang Y; Li, Yang Y; Zhang, Ying Y; Ding, Qingqing Q

Publication Date: 2022-11-03

Variant appearance in text: TP53: 722C>T; S241F

PubMed Link: 36325957

Variant Present in the following documents:

• CAM4-12-6009-s003.xlsx, sheet 1

View BVdb publication page

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Heterogeneity of the cancer cell line metabolic landscape.

Molecular Systems Biology

Shorthouse, David D; Bradley, Jenna J; Critchlow, Susan E SE; Bendtsen, Claus C; Hall, Benjamin A BA

Publication Date: 2022-11

Variant appearance in text: TP53: 722C>T

PubMed Link: 36321551

Variant Present in the following documents:

• MSB-18-e11006-s010.xlsx, sheet 1

View BVdb publication page

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Uterine lavage identifies cancer mutations and increased TP53 somatic mutation burden in individuals with ovarian cancer.

Cancer Research Communications

Ghezelayagh, Talayeh S TS; Kohrn, Brendan F BF; Fredrickson, Jeanne J; Manhardt, Enna E; Radke, Marc R MR; Katz, Ronit R; Gray, Heidi J HJ; Urban, Renata R RR; Pennington, Kathryn P KP; Liao, John B JB; Doll, Kemi M KM; Simons, Elise J EJ; Burzawa, Jennifer K JK; Goff, Barbara A BA; Speiser, Paul P; Swisher, Elizabeth M EM; Norquist, Barbara M BM; Risques, Rosa Ana RA

Publication Date: 2022-10

Variant appearance in text: TP53: 722C>T; S241F

PubMed Link: 36311816

Variant Present in the following documents:

• Main text
• crc-22-0314.pdf
• crc-22-0314-s02.xlsx, sheet 6

View BVdb publication page

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Yes-associated protein 1 mediates initial cell survival during lorlatinib treatment through AKT signaling in ROS1-rearranged lung cancer.

Cancer Science

Yamazoe, Masatoshi M; Ozasa, Hiroaki H; Tsuji, Takahiro T; Funazo, Tomoko T; Yoshida, Hiroshi H; Hashimoto, Kentaro K; Hosoya, Kazutaka K; Ogimoto, Tatsuya T; Ajimizu, Hitomi H; Yoshida, Hironori H; Itotani, Ryo R; Sakamori, Yuichi Y; Kuninaga, Kiyomitsu K; Aoki, Wataru W; Hirai, Toyohiro T

Publication Date: 2022-10-26

Variant appearance in text: TP53: S241F

PubMed Link: 36285485

Variant Present in the following documents:

• Main text
• CAS-114-546.pdf

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Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract.

Cancer Communications (London, England)

Wu, Huanwen H; Yu, Zicheng Z; Liu, Yueping Y; Guo, Lei L; Teng, Lianghong L; Guo, Lingchuan L; Liang, Li L; Wang, Jing J; Gao, Jie J; Li, Ruiyu R; Yang, Ling L; Nie, Xiu X; Su, Dan D; Liang, Zhiyong Z

Publication Date: 2022-10-20

Variant appearance in text: N/A

PubMed Link: 36264285

Variant Present in the following documents:

View BVdb publication page

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Predictive mutation signature of immunotherapy benefits in NSCLC based on machine learning algorithms.

Frontiers In Immunology

Liu, Zhichao Z; Lin, Guo G; Yan, Zeping Z; Li, Linduo L; Wu, Xingchen X; Shi, Jingrong J; He, Jianxing J; Zhao, Lei L; Liang, Hengrui H; Wang, Wei W

Publication Date: 2022

Variant appearance in text: TP53: 722C>T; S241F

PubMed Link: 36238300

Variant Present in the following documents:

• Table_1.xlsx, sheet 4

View BVdb publication page

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Mutually exclusive genetic interactions and gene essentiality shape the genomic landscape of primary melanoma.

The Journal Of Pathology

Birkeälv, Sofia S; Harland, Mark M; Matsuyama, Larissa Satiko Alcantara Sekimoto LSAS; Rashid, Mamun M; Mehta, Ishan I; Laye, Jonathan P JP; Haase, Kerstin K; Mell, Tracey T; Iyer, Vivek V; Robles-Espinoza, Carla Daniela CD; McDermott, Ultan U; van Loo, Peter P; Kuijjer, Marieke L ML; Possik, Patricia A PA; Maria Engler, Silvya Stuchi SS; Bishop, D Timothy DT; Newton-Bishop, Julia J; Adams, David J DJ

Publication Date: 2022-10-11

Variant appearance in text: TP53: 722C>T; S241F

PubMed Link: 36219477

Variant Present in the following documents:

• PATH-259-56-s004.xlsx, sheet 2
• PATH-259-56-s006.xlsx, sheet 2

View BVdb publication page

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Utilization of cytologic cell blocks for targeted sequencing of solid tumors.

Cancer Medicine

Vormittag-Nocito, Erica E; Kumar, Ravindra R; Narayan, Kunwar Digvijay KD; Chen, Zhengjia Z; David, Odile O; Behm, Frederick F; Mohapatra, Gayatry G

Publication Date: 2022-09-20

Variant appearance in text: TP53: 722C>T; S241F

PubMed Link: 36125633

Variant Present in the following documents:

• CAM4-12-4042-s001.xlsx, sheet 1

View BVdb publication page

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EPHA5 mutation was associated with adverse outcome of atezolizumab treatment in late-stage non-small cell lung cancers.

Bmc Pulmonary Medicine

Li, Zhenxiang Z; Zhou, Qing Q; Wang, Qi Q; Wang, Haiyong H; Yue, Weiming W

Publication Date: 2022-09-19

Variant appearance in text: TP53: 722C>T; S241F

PubMed Link: 36123678

Variant Present in the following documents:

• 12890_2022_2161_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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