TP53 c.659A>G ;(p.Y220C)

Variant ID: 17-7578190-T-C

NM_000546.5(TP53):c.659A>G;(p.Y220C)

This variant was identified in 1010 publications

View GRCh38 version.




Publications:


Metabolism-Guided Optimization of Tryptophanol-Derived Isoindolinone p53 Activators.

Pharmaceuticals (Basel, Switzerland)
Barcherini, Valentina V; Loureiro, Joana B JB; Sena, Ana A; Madeira, Catarina C; Leandro, Paula P; Saraiva, Lucília L; Antunes, Alexandra M M AMM; Santos, Maria M M MMM
Publication Date: 2023-01-19

Variant appearance in text: p53: Y220C
PubMed Link: 37259297
Variant Present in the following documents:
  • Main text
  • pharmaceuticals-16-00146.pdf
View BVdb publication page



Targeting the p53 signaling pathway in cancers: Molecular mechanisms and clinical studies.

Medcomm
Shen, Jinze J; Wang, Qurui Q; Mao, Yunan Y; Gao, Wei W; Duan, Shiwei S
Publication Date: 2023-06

Variant appearance in text: p53: Y220C
PubMed Link: 37256211
Variant Present in the following documents:
  • Main text
  • MCO2-4-e288.pdf
View BVdb publication page



Design, Synthesis and Antitumor Activity of 1H-indazole-3-amine Derivatives.

International Journal Of Molecular Sciences
Wang, Congyu C; Zhu, Mei M; Long, Xuesha X; Wang, Qin Q; Wang, Zhenchao Z; Ouyang, Guiping G
Publication Date: 2023-05-12

Variant appearance in text: p53: Y220C
PubMed Link: 37240028
Variant Present in the following documents:
  • ijms-24-08686.pdf
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De novo myelodysplastic syndrome in a Rothmund-Thomson Syndrome patient with novel pathogenic RECQL4 variants.

Blood Science (Baltimore, Md.)
Jiang, Chuanhe C; Zhang, Hao H; Zhao, Chuxian C; Wang, Luxiang L; Hu, Xiaoxia X; Pan, Zengkai Z
Publication Date: 2023-04

Variant appearance in text: TP53: Y220C
PubMed Link: 37228773
Variant Present in the following documents:
  • Main text
  • bs9-5-125.pdf
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The role of molecular testing in pancreatic cancer.

Therapeutic Advances In Gastroenterology
Zhen, David B DB; Safyan, Rachael A RA; Konick, Eric Q EQ; Nguyen, Ryan R; Prichard, Colin C CC; Chiorean, E Gabriela EG
Publication Date: 2023

Variant appearance in text: TP53: Y220C
PubMed Link: 37197396
Variant Present in the following documents:
  • Main text
  • 10.1177_17562848231171456.pdf
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Genomic profiles of IDH-mutant gliomas: MYCN-amplified IDH-mutant astrocytoma had the worst prognosis.

Scientific Reports
Lee, Kwanghoon K; Kim, Seong-Ik SI; Kim, Eric Eunshik EE; Shim, Yu-Mi YM; Won, Jae-Kyung JK; Park, Chul-Kee CK; Choi, Seung Hong SH; Yun, Hongseok H; Lee, Hyunju H; Park, Sung-Hye SH
Publication Date: 2023-04-25

Variant appearance in text: TP53: Tyr220Cys
PubMed Link: 37185778
Variant Present in the following documents:
  • Main text
View BVdb publication page



Acute Myeloid Leukemia Secondary to Chronic Lymphocytic Leukemia After Prolonged Chlorambucil Therapy: A Case Report.

Pharmacogenomics And Personalized Medicine
Wu, Yan Y; Liu, Shan S; Wang, Dongmei D; Yao, Xinjie X
Publication Date: 2023

Variant appearance in text: TP53: Y220C
PubMed Link: 37138655
Variant Present in the following documents:
  • Main text
  • pgpm-16-401.pdf
View BVdb publication page



TP53 somatic mutations in Asian breast cancer are associated with subtype-specific effects.

Breast Cancer Research : Bcr
Ragu, Mohana Eswari ME; Lim, Joanna Mei Ch'wan JMC; Ng, Pei-Sze PS; Yip, Cheng-Har CH; Rajadurai, Pathmanathan P; Teo, Soo-Hwang SH; Pan, Jia-Wern JW
Publication Date: 2023-04-26

Variant appearance in text: TP53: 659A>G; Y220C
PubMed Link: 37101199
Variant Present in the following documents:
  • 13058_2023_1635_MOESM1_ESM.pdf
View BVdb publication page



Genotoxic colibactin mutational signature in colorectal cancer is associated with clinicopathological features, specific genomic alterations and better survival.

Medrxiv : The Preprint Server For Health Sciences
Georgeson, Peter P; Steinfelder, Robert S RS; Harrison, Tabitha A TA; Pope, Bernard J BJ; Zaidi, Syed H SH; Qu, Conghui C; Lin, Yi Y; Joo, Jihoon E JE; Mahmood, Khalid K; Clendenning, Mark M; Walker, Romy R; Aglago, Elom K EK; Berndt, Sonja I SI; Brenner, Hermann H; Campbell, Peter T PT; Cao, Yin Y; Chan, Andrew T AT; Chang-Claude, Jenny J; Dimou, Niki N; Doheny, Kimberly F KF; Drew, David A DA; Figueiredo, Jane C JC; French, Amy J AJ; Gallinger, Steven S; Giannakis, Marios M; Giles, Graham G GG; Goode, Ellen L EL; Gruber, Stephen B SB; Gsur, Andrea A; Gunter, Marc J MJ; Harlid, Sophia S; Hoffmeister, Michael M; Hsu, Li L; Huang, Wen-Yi WY; Huyghe, Jeroen R JR; Manson, JoAnn E JE; Moreno, Victor V; Murphy, Neil N; Nassir, Rami R; Newton, Christina C CC; Nowak, Jonathan A JA; Obón-Santacana, Mireia M; Ogino, Shuji S; Pai, Rish K RK; Papadimitrou, Nikos N; Potter, John D JD; Schoen, Robert E RE; Song, Mingyang M; Sun, Wei W; Toland, Amanda E AE; Trinh, Quang M QM; Tsilidis, Kostas K; Ugai, Tomotaka T; Um, Caroline Y CY; Macrae, Finlay A FA; Rosty, Christophe C; Hudson, Thomas J TJ; Winship, Ingrid M IM; Phipps, Amanda I AI; Jenkins, Mark A MA; Peters, Ulrike U; Buchanan, Daniel D DD
Publication Date: 2023-03-12

Variant appearance in text: TP53: 659A>G
PubMed Link: 37090539
Variant Present in the following documents:
  • Main text
  • media-1.pdf
  • nihpp-2023.03.10.23287127v1.pdf
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Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics.

Blood Cancer Journal
Carter, Bing Z BZ; Mak, Po Yee PY; Tao, Wenjing W; Ayoub, Edward E; Ostermann, Lauren B LB; Huang, Xuelin X; Loghavi, Sanam S; Boettcher, Steffen S; Nishida, Yuki Y; Ruvolo, Vivian V; Hughes, Paul E PE; Morrow, Phuong K PK; Haferlach, Torsten T; Kornblau, Steven S; Muftuoglu, Muharrem M; Andreeff, Michael M
Publication Date: 2023-04-24

Variant appearance in text: TP53: Y220C
PubMed Link: 37088806
Variant Present in the following documents:
  • Main text
  • 41408_2023_Article_830.pdf
View BVdb publication page



Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis.

Cell Death Discovery
Romanovsky, Eva E; Kluck, Klaus K; Ourailidis, Iordanis I; Menzel, Michael M; Beck, Susanne S; Ball, Markus M; Kazdal, Daniel D; Christopoulos, Petros P; Schirmacher, Peter P; Stiewe, Thorsten T; Stenzinger, Albrecht A; Budczies, Jan J
Publication Date: 2023-04-14

Variant appearance in text: TP53: Y220C
PubMed Link: 37059713
Variant Present in the following documents:
  • Main text
  • 41420_2023_Article_1413.pdf
View BVdb publication page



Inhibition of USP14 promotes TNFα-induced cell death in head and neck squamous cell carcinoma (HNSCC).

Cell Death And Differentiation
Morgan, Ethan L EL; Toni, Tiffany T; Viswanathan, Ramya R; Robbins, Yvette Y; Yang, Xinping X; Cheng, Hui H; Gunti, Sreenivasulu S; Huynh, Angel A; Sowers, Anastasia L AL; Mitchell, James B JB; Allen, Clint T CT; Chen, Zhong Z; Van Waes, Carter C
Publication Date: 2023-04-13

Variant appearance in text: TP53: Y220C
PubMed Link: 37055579
Variant Present in the following documents:
  • 41418_2023_1144_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Homologous recombination deficiency derived from whole-genome sequencing predicts platinum response in triple-negative breast cancers.

Nature Communications
Ter Brugge, Petra P; Moser, Sarah C SC; Bièche, Ivan I; Kristel, Petra P; Ibadioune, Sabrina S; Eeckhoutte, Alexandre A; de Bruijn, Roebi R; van der Burg, Eline E; Lutz, Catrin C; Annunziato, Stefano S; de Ruiter, Julian J; Masliah Planchon, Julien J; Vacher, Sophie S; Courtois, Laura L; El-Botty, Rania R; Dahmani, Ahmed A; Montaudon, Elodie E; Morisset, Ludivine L; Sourd, Laura L; Huguet, Léa L; Derrien, Heloise H; Nemati, Fariba F; Chateau-Joubert, Sophie S; Larcher, Thibaut T; Salomon, Anne A; Decaudin, Didier D; Reyal, Fabien F; Coussy, Florence F; Popova, Tatiana T; Wesseling, Jelle J; Stern, Marc-Henri MH; Jonkers, Jos J; Marangoni, Elisabetta E
Publication Date: 2023-04-07

Variant appearance in text: TP53: Y220C; rs121912666
PubMed Link: 37029129
Variant Present in the following documents:
  • 41467_2023_37537_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Publication Date: 2023-04-03

Variant appearance in text: TP53: Y220C
PubMed Link: 37012232
Variant Present in the following documents:
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
View BVdb publication page



Precise pancreatic cancer therapy through targeted degradation of mutant p53 protein by cerium oxide nanoparticles.

Journal Of Nanobiotechnology
Zhang, Hao H; Zhang, Wang W; Hu, Bochuan B; Qin, Xiaohua X; Yi, Tianxiang T; Ye, Yayi Y; Huang, Xiaowan X; Song, Yang Y; Yang, Zhenyu Z; Qian, Jieying J; Zhang, Yunjiao Y
Publication Date: 2023-04-01

Variant appearance in text: p53: Y220C
PubMed Link: 37005668
Variant Present in the following documents:
  • Main text
  • 12951_2023_Article_1867.pdf
View BVdb publication page



Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers.

Bmc Cancer
Xie, Jianjiang J; Yao, Weishen W; Chen, Lingxiu L; Zhu, Wenjun W; Liu, Qiang Q; Geng, Geng G; Fang, Jing J; Zhao, Yang Y; Xiao, Li L; Huang, Zhenhua Z; Zhao, Jing J
Publication Date: 2023-03-31

Variant appearance in text: TP53: Tyr220Cys
PubMed Link: 37004022
Variant Present in the following documents:
  • 12885_2023_10674_MOESM1_ESM.xlsx, sheet 1
  • 12885_2023_10674_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Targeting FGFR Pathway Is Not an Effective Therapeutic Strategy in Patients with Unselected Metastatic Esophagogastric Cancer Resistant to Trastuzumab.

Journal Of Personalized Medicine
Zecchetto, Camilla C; Quinzii, Alberto A; Casalino, Simona S; Gaule, Marina M; Pesoni, Camilla C; Merz, Valeria V; Pietrobono, Silvia S; Mangiameli, Domenico D; Pasquato, Martina M; Milleri, Stefano S; Giacopuzzi, Simone S; Bencivenga, Maria M; Tomezzoli, Anna A; de Manzoni, Giovanni G; Melisi, Davide D
Publication Date: 2023-03-11

Variant appearance in text: TP53: Y220C
PubMed Link: 36983691
Variant Present in the following documents:
  • jpm-13-00508.pdf
View BVdb publication page



Reduced Levels of Misfolded and Aggregated Mutant p53 by Proteostatic Activation.

Cells
Naus, Evelyne E; Derweduwe, Marleen M; Lampi, Youlia Y; Claeys, Annelies A; Pauwels, Jarne J; Langenberg, Tobias T; Claes, Filip F; Xu, Jie J; Haemels, Veerle V; Atak, Zeynep Kalender ZK; van der Kant, Rob R; Van Durme, Joost J; De Baets, Greet G; Ligon, Keith L KL; Fiers, Mark M; Gevaert, Kris K; Aerts, Stein S; Rousseau, Frederic F; Schymkowitz, Joost J; De Smet, Frederik F
Publication Date: 2023-03-21

Variant appearance in text: p53: Y220C
PubMed Link: 36980299
Variant Present in the following documents:
  • Main text
  • cells-12-00960.pdf
View BVdb publication page



Circulating Tumor DNA Monitoring Reveals Molecular Progression before Radiologic Progression in a Real-life Cohort of Patients with Advanced Non-small Cell Lung Cancer.

Cancer Research Communications
Frank, Malene S MS; Andersen, Christina S A CSA; Ahlborn, Lise B LB; Pallisgaard, Niels N; Bodtger, Uffe U; Gehl, Julie J
Publication Date: 2022-10

Variant appearance in text: TP53: 659A>G; Y220C
PubMed Link: 36969747
Variant Present in the following documents:
  • crc-22-0258-s08.xlsx, sheet 1
View BVdb publication page



Different impacts of TP53 mutations on cell cycle-related gene expression among cancer types.

Scientific Reports
Sasaki, Keiju K; Takahashi, Shin S; Ouchi, Kota K; Otsuki, Yasufumi Y; Wakayama, Shonosuke S; Ishioka, Chikashi C
Publication Date: 2023-03-24

Variant appearance in text: TP53: Y220C
PubMed Link: 36964217
Variant Present in the following documents:
  • 41598_2023_32092_MOESM1_ESM.xlsx, sheet 4
View BVdb publication page



Novel Scheme for Defining the Clinical Implications of TP53 Mutations in Myeloid Neoplasia.

Research Square
Bahaj, Waled W; Kewan, Tariq T; Gurnari, Carmelo C; Durmaz, Arda A; Ponvilawan, Ben B; Pandit, Ishani I; Kubota, Yasuo Y; Ogbue, Olisaemeka D OD; Zawit, Misam M; Madanat, Yazan Y; Bat, Taha T; Balasubramanian, Suresh K SK; Awada, Hussein H; Ahmed, Ramsha R; Mori, Minako M; Meggendorfer, Manja M; Haferlach, Torsten T; Visconte, Valeria V; Maciejewski, Jaroslaw P JP
Publication Date: 2023-03-09

Variant appearance in text: TP53: Y220C
PubMed Link: 36945617
Variant Present in the following documents:
  • nihpp-rs2656206v1.pdf
View BVdb publication page



Role of p53 in breast cancer progression: An insight into p53 targeted therapy.

Theranostics
Marvalim, Charlie C; Datta, Arpita A; Lee, Soo Chin SC
Publication Date: 2023

Variant appearance in text: p53: Y220C
PubMed Link: 36923534
Variant Present in the following documents:
  • Main text
  • thnov13p1421.pdf
View BVdb publication page



Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.

Cancer Research Communications
White, Jason A JA; Kaninjing, Ernest T ET; Adeniji, Kayode A KA; Jibrin, Paul P; Obafunwa, John O JO; Ogo, Chidiebere N CN; Mohammed, Faruk F; Popoola, Ademola A; Fatiregun, Omolara A OA; Oluwole, Olabode P OP; Karanam, Balasubramanyam B; Elhussin, Isra I; Ambs, Stefan S; Tang, Wei W; Davis, Melissa M; Polak, Paz P; Campbell, Moray J MJ; Brignole, Kathryn R KR; Rotimi, Solomon O SO; Dean-Colomb, Windy W; Odedina, Folake T FT; Martin, Damali N DN; Yates, Clayton C
Publication Date: 2022-09

Variant appearance in text: N/A
PubMed Link: 36922933
Variant Present in the following documents:
View BVdb publication page



Whole-genome sequencing of 20 cholangiocarcinoma cases reveals unique profiles in patients with cirrhosis and primary sclerosing cholangitis.

Journal Of Gastrointestinal Oncology
Holzapfel, Nicholas N; Zhang, Amy A; Choi, Woo-Jin WJ; Denroche, Robert R; Jang, Gunho G; Dodd, Anna A; Bucur, Roxana R; Wilson, Julie J; Sapisochin, Gonzalo G; Notta, Faiyaz F; Grant, Robert C RC; Gallinger, Steven S; Knox, Jennifer J JJ; O'Kane, Grainne M GM
Publication Date: 2023-02-28

Variant appearance in text: TP53: Y220C
PubMed Link: 36915452
Variant Present in the following documents:
  • Main text
  • jgo-14-01-379.pdf
View BVdb publication page



Case Report: The effective treatment of patients in advanced no-small cell lung cancer patients with EGFR G719X/S768I/L861Q and acquired MET amplification: A case series and literature review.

Frontiers In Oncology
Zhao, Yun Y; Su, Cuiyun C; Shi, Lina L; Luo, Wenqi W; Liu, Zhen Z; Liang, Chuqiao C; Wang, Huilin H; Ning, Ruiling R; Yu, Qitao Q; Jiang, Wei W
Publication Date: 2023

Variant appearance in text: TP53: 659A>G; Y220C
PubMed Link: 36910616
Variant Present in the following documents:
  • Main text
  • fonc-13-1126325.pdf
View BVdb publication page



Evaluation of AlphaFold structure-based protein stability prediction on missense variations in cancer.

Frontiers In Genetics
Keskin Karakoyun, Hilal H; Yüksel, Şirin K ŞK; Amanoglu, Ilayda I; Naserikhojasteh, Lara L; Yeşilyurt, Ahmet A; Yakıcıer, Cengiz C; Timuçin, Emel E; Akyerli, Cemaliye B CB
Publication Date: 2023

Variant appearance in text: TP53: Y220C
PubMed Link: 36896237
Variant Present in the following documents:
  • Table1.xlsx, sheet 1
View BVdb publication page



The DNA damage response pathway regulates the expression of the immune checkpoint CD47.

Communications Biology
Ghantous, Lucy L; Volman, Yael Y; Hefez, Ruth R; Wald, Ori O; Stern, Esther E; Friehmann, Tomer T; Chajut, Ayelet A; Bremer, Edwin E; Elhalel, Michal Dranitzki MD; Rachmilewitz, Jacob J
Publication Date: 2023-03-07

Variant appearance in text: p53: Y220C
PubMed Link: 36882648
Variant Present in the following documents:
  • Main text
  • 42003_2023_Article_4615.pdf
View BVdb publication page



Integration of deep learning with Ramachandran plot molecular dynamics simulation for genetic variant classification.

Iscience
Tam, Benjamin B; Qin, Zixin Z; Zhao, Bojin B; Wang, San Ming SM; Lei, Chon Lok CL
Publication Date: 2023-03-17

Variant appearance in text: TP53: 659A>G; Y220C
PubMed Link: 36879825
Variant Present in the following documents:
  • mmc2.xlsx, sheet 1
  • mmc3.xlsx, sheet 1
  • mmc4.xlsx, sheet 1
View BVdb publication page



A Phenogenetic Axis that Modulates Clinical Manifestation and Predicts Treatment Outcome in Primary Myeloid Neoplasms.

Cancer Research Communications
Shen, Qiujin Q; Feng, Yahui Y; Gong, Xiaowen X; Jia, Yujiao Y; Gao, Qingyan Q; Jiao, Xiaokang X; Qi, Saibing S; Liu, Xueou X; Wei, Hui H; Huang, Bingqing B; Zhao, Ningning N; Song, Xiaoqiang X; Ma, Yueshen Y; Liang, Shihao S; Zhang, Donglei D; Qin, Li L; Wang, Ying Y; Qu, Shiqiang S; Zou, Yao Y; Chen, Yumei Y; Guo, Ye Y; Yi, Shuhua S; An, Gang G; Jiao, Zengtao Z; Zhang, Song S; Li, Linfeng L; Yan, Jun J; Wang, Huijun H; Song, Zhen Z; Mi, Yingchang Y; Qiu, Lugui L; Zhu, Xiaofan X; Wang, Jianxiang J; Xiao, Zhijian Z; Chen, Junren J
Publication Date: 2022-04

Variant appearance in text: TP53: 659A>G; Y220C
PubMed Link: 36873623
Variant Present in the following documents:
  • crc-21-0194-s05.xlsx, sheet 1
View BVdb publication page



Plant-derived natural products and combination therapy in liver cancer.

Frontiers In Oncology
Wang, Yuqin Y; Li, Jinyao J; Xia, Lijie L
Publication Date: 2023

Variant appearance in text: p53: Y220C
PubMed Link: 36865794
Variant Present in the following documents:
  • Main text
  • fonc-13-1116532.pdf
View BVdb publication page



Codon-specific KRAS mutations predict survival benefit of trifluridine/tipiracil in metastatic colorectal cancer.

Nature Medicine
van de Haar, Joris J; Ma, Xuhui X; Ooft, Salo N SN; van der Helm, Pim W PW; Hoes, Louisa R LR; Mainardi, Sara S; Pinato, David J DJ; Sun, Kristi K; Salvatore, Lisa L; Tortora, Giampaolo G; Zurlo, Ina Valeria IV; Leo, Silvana S; Giampieri, Riccardo R; Berardi, Rossana R; Gelsomino, Fabio F; Merz, Valeria V; Mazzuca, Federica F; Antonuzzo, Lorenzo L; Rosati, Gerardo G; Stavraka, Chara C; Ross, Paul P; Rodriquenz, Maria Grazia MG; Pavarana, Michele M; Messina, Carlo C; Iveson, Timothy T; Zoratto, Federica F; Thomas, Anne A; Fenocchio, Elisabetta E; Ratti, Margherita M; Depetris, Ilaria I; Cergnul, Massimiliano M; Morelli, Cristina C; Libertini, Michela M; Parisi, Alessandro A; De Tursi, Michele M; Zanaletti, Nicoletta N; Garrone, Ornella O; Graham, Janet J; Longarini, Raffaella R; Gobba, Stefania Maria SM; Petrillo, Angelica A; Tamburini, Emiliano E; La Verde, Nicla N; Petrelli, Fausto F; Ricci, Vincenzo V; Wessels, Lodewyk F A LFA; Ghidini, Michele M; Cortellini, Alessio A; Voest, Emile E EE; Valeri, Nicola N
Publication Date: 2023-03-02

Variant appearance in text: TP53: Tyr220Cys
PubMed Link: 36864254
Variant Present in the following documents:
  • 41591_2023_2240_MOESM2_ESM.xlsx, sheet 4
View BVdb publication page



Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery
Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI
Publication Date: 2023-03-02

Variant appearance in text: TP53: 659A>G; Y220C; rs121912666
PubMed Link: 36862804
Variant Present in the following documents:
  • cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 6
View BVdb publication page



MetalProGNet: a structure-based deep graph model for metalloprotein-ligand interaction predictions.

Chemical Science
Jiang, Dejun D; Ye, Zhaofeng Z; Hsieh, Chang-Yu CY; Yang, Ziyi Z; Zhang, Xujun X; Kang, Yu Y; Du, Hongyan H; Wu, Zhenxing Z; Wang, Jike J; Zeng, Yundian Y; Zhang, Haotian H; Wang, Xiaorui X; Wang, Mingyang M; Yao, Xiaojun X; Zhang, Shengyu S; Wu, Jian J; Hou, Tingjun T
Publication Date: 2023-02-22

Variant appearance in text: p53: Y220C
PubMed Link: 36845922
Variant Present in the following documents:
  • SC-014-D2SC06576B-s003.xlsx, sheet 1
View BVdb publication page



Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23

Variant appearance in text: TP53: 659A>G; Tyr220Cys
PubMed Link: 36823319
Variant Present in the following documents:
  • 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



OPUS-Mut: Studying the Effect of Protein Mutation through Side-Chain Modeling.

Journal Of Chemical Theory And Computation
Xu, Gang G; Wang, Qinghua Q; Ma, Jianpeng J
Publication Date: 2023-02-22

Variant appearance in text: p53: Y220C
PubMed Link: 36813264
Variant Present in the following documents:
  • Main text
  • ct2c00847.pdf
View BVdb publication page



Clinical impact of TP53 disruption in chronic lymphocytic leukemia patients treated with ibrutinib: a campus CLL study.

Leukemia
Bomben, Riccardo R; Rossi, Francesca Maria FM; Vit, Filippo F; Bittolo, Tamara T; Zucchetto, Antonella A; Papotti, Robel R; Tissino, Erika E; Pozzo, Federico F; Degan, Massimo M; Polesel, Jerry J; Bulian, Pietro P; Marasca, Roberto R; Reda, Gianluigi G; Laurenti, Luca L; Olivieri, Jacopo J; Chiarenza, Annalisa A; Laureana, Roberta R; Postorino, Massimiliano M; Del Principe, Maria Ilaria MI; Cuneo, Antonio A; Gentile, Massimo M; Morabito, Fortunato F; Fronza, Gilberto G; Tafuri, Agostino A; Zaja, Francesco F; Foà, Robin R; Di Raimondo, Francesco F; Del Poeta, Giovanni G; Gattei, Valter V
Publication Date: 2023-02-18

Variant appearance in text: TP53: 659A>G; Y220C
PubMed Link: 36807650
Variant Present in the following documents:
  • 41375_2023_1845_MOESM1_ESM.pdf
View BVdb publication page



Impact of gene alterations on clinical outcome in young adults with myelodysplastic syndromes.

Scientific Reports
Konishi, Tatsuya T; Sadato, Daichi D; Toya, Takashi T; Hirama, Chizuko C; Kishida, Yuya Y; Nagata, Akihito A; Yamada, Yuta Y; Shingai, Naoki N; Shimizu, Hiroaki H; Najima, Yuho Y; Kobayashi, Takeshi T; Haraguchi, Kyoko K; Okuyama, Yoshiki Y; Harada, Hironori H; Ohashi, Kazuteru K; Harada, Yuka Y; Doki, Noriko N
Publication Date: 2023-02-14

Variant appearance in text: TP53: 659A>G; Tyr220Cys
PubMed Link: 36788335
Variant Present in the following documents:
  • 41598_2023_29794_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



Multilevel proteomic analyses reveal molecular diversity between diffuse-type and intestinal-type gastric cancer.

Nature Communications
Shi, Wenhao W; Wang, Yushen Y; Xu, Chen C; Li, Yan Y; Ge, Sai S; Bai, Bin B; Zhang, Kecheng K; Wang, Yunzhi Y; Zheng, Nairen N; Wang, Juan J; Wang, Shiqi S; Ji, Gang G; Li, Jipeng J; Nie, Yongzhan Y; Liang, Wenquan W; Wu, Xiaosong X; Cui, Jianxin J; Wang, Yi Y; Chen, Lin L; Zhao, Qingchuan Q; Shen, Lin L; He, Fuchu F; Qin, Jun J; Ding, Chen C
Publication Date: 2023-02-14

Variant appearance in text: TP53: 659A>G; Tyr220Cys
PubMed Link: 36788224
Variant Present in the following documents:
  • 41467_2023_35797_MOESM4_ESM.xlsx, sheet 2
View BVdb publication page