TP53 c.643_644delinsGA ;(p.S215D)

Variant ID: 17-7578205-CT-TC

NM_000546.5(TP53):c.643_644delinsGA;(p.S215D)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Mek1 coordinates meiotic progression with DNA break repair by directly phosphorylating and inhibiting the yeast pachytene exit regulator Ndt80.

Plos Genetics
Chen, Xiangyu X; Gaglione, Robert R; Leong, Trevor T; Bednor, Lauren L; de Los Santos, Teresa T; Luk, Ed E; Airola, Michael M; Hollingsworth, Nancy M NM
Publication Date: 2018-11

Variant appearance in text: p53: S215D
PubMed Link: 30496175
Variant Present in the following documents:
  • Main text
  • pgen.1007832.pdf
View BVdb publication page



Mutant TP53 posttranslational modifications: challenges and opportunities.

Human Mutation
Nguyen, Thuy-Ai TA; Menendez, Daniel D; Resnick, Michael A MA; Anderson, Carl W CW
Publication Date: 2014-06

Variant appearance in text: TP53: Ser215Asp
PubMed Link: 24395704
Variant Present in the following documents:
  • Main text
View BVdb publication page



Aurora kinase-A inactivates DNA damage-induced apoptosis and spindle assembly checkpoint response functions of p73.

Cancer Cell
Katayama, Hiroshi H; Wang, Jin J; Treekitkarnmongkol, Warapen W; Kawai, Hidehiko H; Sasai, Kaori K; Zhang, Hui H; Wang, Hua H; Adams, Henry P HP; Jiang, Shoulei S; Chakraborty, Sandip N SN; Suzuki, Fumio F; Arlinghaus, Ralph B RB; Liu, Jinsong J; Mobley, James A JA; Grizzle, William E WE; Wang, Huamin H; Sen, Subrata S
Publication Date: 2012-02-14

Variant appearance in text: p53: S215D
PubMed Link: 22340593
Variant Present in the following documents:
  • Main text
View BVdb publication page



Aurora A mediates cross-talk between N- and C-terminal post-translational modifications of p53.

Cancer Biology & Therapy
Warnock, Lorna Jane LJ; Raines, Sally Anne SA; Milner, Jo J
Publication Date: 2011-12-15

Variant appearance in text: p53: S215D
PubMed Link: 22157150
Variant Present in the following documents:
  • Main text
View BVdb publication page



A novel p53 phosphorylation site within the MDM2 ubiquitination signal: II. a model in which phosphorylation at SER269 induces a mutant conformation to p53.

The Journal Of Biological Chemistry
Fraser, Jennifer A JA; Madhumalar, Arumugam A; Blackburn, Elizabeth E; Bramham, Janice J; Walkinshaw, Malcolm D MD; Verma, Chandra C; Hupp, Ted R TR
Publication Date: 2010-11-26

Variant appearance in text: p53: S215D
PubMed Link: 20847049
Variant Present in the following documents:
  • Main text
View BVdb publication page