TP53 c.586_587delinsAA ;(p.R196K)

Variant ID: 17-7578262-CG-TT

NM_000546.5(TP53):c.586_587delinsAA;(p.R196K)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Profiling PRMT methylome reveals roles of hnRNPA1 arginine methylation in RNA splicing and cell growth.

Nature Communications
Li, Wen-Juan WJ; He, Yao-Hui YH; Yang, Jing-Jing JJ; Hu, Guo-Sheng GS; Lin, Yi-An YA; Ran, Ting T; Peng, Bing-Ling BL; Xie, Bing-Lan BL; Huang, Ming-Feng MF; Gao, Xiang X; Huang, Hai-Hua HH; Zhu, Helen He HH; Ye, Feng F; Liu, Wen W
Publication Date: 2021-03-29

Variant appearance in text: p53: R196K
PubMed Link: 33782401
Variant Present in the following documents:
  • Main text
  • 41467_2021_Article_21963.pdf
View BVdb publication page



A pediatric brain tumor atlas of genes deregulated by somatic genomic rearrangement.

Nature Communications
Zhang, Yiqun Y; Chen, Fengju F; Donehower, Lawrence A LA; Scheurer, Michael E ME; Creighton, Chad J CJ
Publication Date: 2021-02-10

Variant appearance in text: TP53: Arg196Lys
PubMed Link: 33568653
Variant Present in the following documents:
  • 41467_2021_21081_MOESM8_ESM.xlsx, sheet 3
View BVdb publication page



Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer.

Nature Metabolism
Bader, David A DA; Hartig, Sean M SM; Putluri, Vasanta V; Foley, Christopher C; Hamilton, Mark P MP; Smith, Eric A EA; Saha, Pradip K PK; Panigrahi, Anil A; Walker, Christopher C; Zong, Lin L; Martini-Stoica, Heidi H; Chen, Rui R; Rajapakshe, Kimal K; Coarfa, Cristian C; Sreekumar, Arun A; Mitsiades, Nicholas N; Bankson, James A JA; Ittmann, Michael M MM; O'Malley, Bert W BW; Putluri, Nagireddy N; McGuire, Sean E SE
Publication Date: 2019-01

Variant appearance in text: p53: R196K
PubMed Link: 31198906
Variant Present in the following documents:
  • NIHMS1508495-supplement-Data_Set_1.xlsx, sheet 5
  • NIHMS1508495-supplement-Data_Set_1.xlsx, sheet 6
View BVdb publication page



Identification of arrestin-3-specific residues necessary for JNK3 kinase activation.

The Journal Of Biological Chemistry
Seo, Jungwon J; Tsakem, Elviche L EL; Breitman, Maya M; Gurevich, Vsevolod V VV
Publication Date: 2011-08-12

Variant appearance in text: p53: R196K
PubMed Link: 21715332
Variant Present in the following documents:
  • Main text
View BVdb publication page



Huntington's disease: the case for genetic modifiers.

Genome Medicine
Gusella, James F JF; MacDonald, Marcy E ME
Publication Date: 2009-08-21

Variant appearance in text: TP53: R196K
PubMed Link: 19725930
Variant Present in the following documents:
  • gm80.pdf
View BVdb publication page



Age at onset of Huntington disease is not modulated by the R72P variation in TP53 and the R196K variation in the gene coding for the human caspase activated DNase (hCAD).

Bmc Medical Genetics
Arning, Larissa L; Kraus, Peter H PH; Saft, Carsten C; Andrich, Jürgen J; Epplen, Jörg T JT
Publication Date: 2005-10-03

Variant appearance in text: TP53: R196K
PubMed Link: 16202123
Variant Present in the following documents:
  • Main text
  • 1471-2350-6-35.pdf
View BVdb publication page