TP53 c.558del ;(p.D186Efs*61)

Variant ID: 17-7578372-CA-C

NM_000546.5(TP53):c.558del;(p.D186Efs*61)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways.

Nature Communications
Zhang, Yiqun Y; Chen, Fengju F; Chandrashekar, Darshan S DS; Varambally, Sooryanarayana S; Creighton, Chad J CJ
Publication Date: 2022-05-13

Variant appearance in text: p53: D186Efs*61
PubMed Link: 35562349
Variant Present in the following documents:
  • 41467_2022_30342_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Pure erythroid leukemia is characterized by biallelic TP53 inactivation and abnormal p53 expression patterns in de novo and secondary cases.

Haematologica
Fang, Hong H; Wang, Sa A SA; Khoury, Joseph D JD; El Hussein, Siba S; Kim, Do Hwan DH; Tashakori, Mehrnoosh M; Tang, Zhenya Z; Li, Shaoying S; Hu, Zhihong Z; Jelloul, Fatima Zahra FZ; Patel, Keyur P KP; McDonnell, Timothy J TJ; Kadia, Tapan T; Medeiros, L Jeffrey LJ; Wang, Wei W
Publication Date: 2022-09-01

Variant appearance in text: p53: 558del
PubMed Link: 35511670
Variant Present in the following documents:
  • 1072232.pdf
View BVdb publication page