TP53 c.557A>C ;(p.D186A)

Variant ID: 17-7578373-T-G

NM_000546.5(TP53):c.557A>C;(p.D186A)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


Calorie restriction alters the mechanisms of radiation-induced mouse thymic lymphomagenesis.

Plos One
Nakayama, Takafumi T; Sunaoshi, Masaaki M; Shang, Yi Y; Takahashi, Mizuki M; Saito, Takato T; Blyth, Benjamin J BJ; Amasaki, Yoshiko Y; Daino, Kazuhiro K; Shimada, Yoshiya Y; Tachibana, Akira A; Kakinuma, Shizuko S
Publication Date: 2023

Variant appearance in text: p53: 557A>C
PubMed Link: 36662808
Variant Present in the following documents:
  • Main text
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: TP53: D186A
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: TP53: D186A
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
View BVdb publication page



The demethylase NMAD-1 regulates DNA replication and repair in the Caenorhabditis elegans germline.

Plos Genetics
Wang, Simon Yuan SY; Mao, Hui H; Shibuya, Hiroki H; Uzawa, Satoru S; O'Brown, Zach Klapholz ZK; Wesenberg, Sage S; Shin, Nara N; Saito, Takamune T TT; Gao, Jinmin J; Meyer, Barbara J BJ; Colaiácovo, Monica P MP; Greer, Eric Lieberman EL
Publication Date: 2019-07

Variant appearance in text: p53: D186A
PubMed Link: 31283754
Variant Present in the following documents:
  • Main text
View BVdb publication page



Identification of potentially oncogenic alterations from tumor-only samples reveals Fanconi anemia pathway mutations in bladder carcinomas.

Npj Genomic Medicine
Madubata, Chioma J CJ; Roshan-Ghias, Alireza A; Chu, Timothy T; Resnick, Samuel S; Zhao, Junfei J; Arnes, Luis L; Wang, Jiguang J; Rabadan, Raul R
Publication Date: 2017

Variant appearance in text: TP53: D186A
PubMed Link: 29263839
Variant Present in the following documents:
  • 41525_2017_32_MOESM8_ESM.xlsx, sheet 3
View BVdb publication page



iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports
Wang, Meng M; Wei, Liping L
Publication Date: 2016-08-16

Variant appearance in text: TP53: D186A
PubMed Link: 27527004
Variant Present in the following documents:
  • srep31321-s5.xls, sheet 1
View BVdb publication page



Alterations in Mitochondrial and Endoplasmic Reticulum Signaling by p53 Mutants.

Frontiers In Oncology
Giorgi, Carlotta C; Bonora, Massimo M; Missiroli, Sonia S; Morganti, Claudia C; Morciano, Giampaolo G; Wieckowski, Mariusz R MR; Pinton, Paolo P
Publication Date: 2016

Variant appearance in text: p53: D186A
PubMed Link: 26942128
Variant Present in the following documents:
  • Main text
  • fonc-06-00042.pdf
View BVdb publication page



The DNA-binding domain mediates both nuclear and cytosolic functions of p53.

Nature Structural & Molecular Biology
Follis, Ariele Viacava AV; Llambi, Fabien F; Ou, Li L; Baran, Katherine K; Green, Douglas R DR; Kriwacki, Richard W RW
Publication Date: 2014-06

Variant appearance in text: p53: D186A
PubMed Link: 24814347
Variant Present in the following documents:
  • Main text
View BVdb publication page



ATPase activity and ATP-dependent conformational change in the co-chaperone HSP70/HSP90-organizing protein (HOP).

The Journal Of Biological Chemistry
Yamamoto, Soh S; Subedi, Ganesh Prasad GP; Hanashima, Shinya S; Satoh, Tadashi T; Otaka, Michiro M; Wakui, Hideki H; Sawada, Ken-ichi K; Yokota, Shin-ichi S; Yamaguchi, Yoshiki Y; Kubota, Hiroshi H; Itoh, Hideaki H
Publication Date: 2014-04-04

Variant appearance in text: p53: D186A
PubMed Link: 24535459
Variant Present in the following documents:
  • Main text
View BVdb publication page



Highly homologous eEF1A1 and eEF1A2 exhibit differential post-translational modification with significant enrichment around localised sites of sequence variation.

Biology Direct
Soares, Dinesh C DC; Abbott, Catherine M CM
Publication Date: 2013-11-13

Variant appearance in text: p53: D186A
PubMed Link: 24220286
Variant Present in the following documents:
  • Main text
  • 1745-6150-8-29.pdf
View BVdb publication page