TP53 c.547T>G ;(p.S183A)

Variant ID: 17-7578383-A-C

NM_000546.5(TP53):c.547T>G;(p.S183A)

This variant was identified in 11 publications

View GRCh38 version.




Publications:


USP7 controls NGN3 stability and pancreatic endocrine lineage development.

Nature Communications
Manea, Teodora T; Nelson, Jessica Kristine JK; Garrone, Cristina Maria CM; Hansson, Karin K; Evans, Ian I; Behrens, Axel A; Sancho, Rocio R
Publication Date: 2023-04-28

Variant appearance in text: p53: S183A
PubMed Link: 37117185
Variant Present in the following documents:
  • Main text
View BVdb publication page



Meta-analysis of commonly mutated genes in leptomeningeal carcinomatosis.

Peerj
Congur, Irem I; Koni, Ekin E; Onat, Onur Emre OE; Tokcaer Keskin, Zeynep Z
Publication Date: 2023

Variant appearance in text: TP53: Ser183Ala
PubMed Link: 37096065
Variant Present in the following documents:
  • peerj-11-15250-s005.xlsx, sheet 1
View BVdb publication page



Prognostic value of baseline genetic features and newly identified TP53 mutations in advanced breast cancer.

Molecular Oncology
Zhang, Lanxin L; Sun, Siwen S; Zhao, Xiaotian X; Liu, Jingwen J; Xu, Yang Y; Xu, Lingzhi L; Song, Chen C; Li, Na N; Yu, Jing J; Zhao, Shanshan S; Yu, Peiyao P; Fang, Fengqi F; Xie, Jiping J; Ji, Xuening X; Yu, Ruoying R; Ou, Qiuxiang Q; Zhao, Zuowei Z; Li, Man M
Publication Date: 2022-10

Variant appearance in text: TP53: 547T>G; S183A
PubMed Link: 35971249
Variant Present in the following documents:
  • MOL2-16-3689-s003.xlsx, sheet 1
View BVdb publication page



The Cross Talk Between p53 and mTOR Pathways in Response to Physiological and Genotoxic Stresses.

Frontiers In Cell And Developmental Biology
Cui, Danrui D; Qu, Ruirui R; Liu, Dian D; Xiong, Xiufang X; Liang, Tingbo T; Zhao, Yongchao Y
Publication Date: 2021

Variant appearance in text: p53: S183A
PubMed Link: 34869377
Variant Present in the following documents:
  • Main text
View BVdb publication page



Rely on Each Other: DNA Binding Cooperativity Shapes p53 Functions in Tumor Suppression and Cancer Therapy.

Cancers
Timofeev, Oleg O; Stiewe, Thorsten T
Publication Date: 2021-05-17

Variant appearance in text: p53: S183A
PubMed Link: 34067731
Variant Present in the following documents:
  • Main text
  • cancers-13-02422.pdf
View BVdb publication page



Mdm2 phosphorylation by Akt regulates the p53 response to oxidative stress to promote cell proliferation and tumorigenesis.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Chibaya, Loretah L; Karim, Baktiar B; Zhang, Hong H; Jones, Stephen N SN
Publication Date: 2021-01-26

Variant appearance in text: p53: S183A
PubMed Link: 33468664
Variant Present in the following documents:
  • Main text
View BVdb publication page



iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports
Wang, Meng M; Wei, Liping L
Publication Date: 2016-08-16

Variant appearance in text: TP53: S183A
PubMed Link: 27527004
Variant Present in the following documents:
  • srep31321-s5.xls, sheet 1
View BVdb publication page



Comparative Analysis of Muscle Transcriptome between Pig Genotypes Identifies Genes and Regulatory Mechanisms Associated to Growth, Fatness and Metabolism.

Plos One
Ayuso, Miriam M; Fernández, Almudena A; Núñez, Yolanda Y; Benítez, Rita R; Isabel, Beatriz B; Barragán, Carmen C; Fernández, Ana Isabel AI; Rey, Ana Isabel AI; Medrano, Juan F JF; Cánovas, Ángela Á; González-Bulnes, Antonio A; López-Bote, Clemente C; Ovilo, Cristina C
Publication Date: 2015

Variant appearance in text: TP53: 547T>G; Ser183Ala
PubMed Link: 26695515
Variant Present in the following documents:
  • pone.0145162.s006.xlsx, sheet 1
View BVdb publication page



Aurora B kinase phosphorylates and instigates degradation of p53.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Gully, Chris P CP; Velazquez-Torres, Guermarie G; Shin, Ji-Hyun JH; Fuentes-Mattei, Enrique E; Wang, Edward E; Carlock, Colin C; Chen, Jian J; Rothenberg, Daniel D; Adams, Henry P HP; Choi, Hyun Ho HH; Guma, Sergei S; Phan, Liem L; Chou, Ping-Chieh PC; Su, Chun-Hui CH; Zhang, Fanmao F; Chen, Jiun-Sheng JS; Yang, Tsung-Ying TY; Yeung, Sai-Ching J SC; Lee, Mong-Hong MH
Publication Date: 2012-06-12

Variant appearance in text: p53: S183A
PubMed Link: 22611192
Variant Present in the following documents:
  • Main text
View BVdb publication page



Aurora B interacts with NIR-p53, leading to p53 phosphorylation in its DNA-binding domain and subsequent functional suppression.

The Journal Of Biological Chemistry
Wu, Liming L; Ma, Chi A CA; Zhao, Yongge Y; Jain, Ashish A
Publication Date: 2011-01-21

Variant appearance in text: p53: S183A
PubMed Link: 20959462
Variant Present in the following documents:
  • Main text
View BVdb publication page



The tumor suppressor PP2A Abeta regulates the RalA GTPase.

Cell
Sablina, Anna A AA; Chen, Wen W; Arroyo, Jason D JD; Corral, Laura L; Hector, Melissa M; Bulmer, Sara E SE; DeCaprio, James A JA; Hahn, William C WC
Publication Date: 2007-06-01

Variant appearance in text: p53: S183A
PubMed Link: 17540176
Variant Present in the following documents:
  • Main text
View BVdb publication page