Publications:

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Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis.

Cell Death Discovery

Romanovsky, Eva E; Kluck, Klaus K; Ourailidis, Iordanis I; Menzel, Michael M; Beck, Susanne S; Ball, Markus M; Kazdal, Daniel D; Christopoulos, Petros P; Schirmacher, Peter P; Stiewe, Thorsten T; Stenzinger, Albrecht A; Budczies, Jan J

Publication Date: 2023-04-14

Variant appearance in text: TP53: E180R

PubMed Link: 37059713

Variant Present in the following documents:

• Main text
• 41420_2023_Article_1413.pdf

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Mutant p53: it's not all one and the same.

Cell Death And Differentiation

Kennedy, Margaret C MC; Lowe, Scott W SW

Publication Date: 2022-05

Variant appearance in text: p53: E180R

PubMed Link: 35361963

Variant Present in the following documents:

• Main text
• 41418_2022_Article_989.pdf

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p53 partial loss-of-function mutations sensitize to chemotherapy.

Oncogene

Klimovich, Boris B; Merle, Nastasja N; Neumann, Michelle M; Elmshäuser, Sabrina S; Nist, Andrea A; Mernberger, Marco M; Kazdal, Daniel D; Stenzinger, Albrecht A; Timofeev, Oleg O; Stiewe, Thorsten T

Publication Date: 2022-02

Variant appearance in text: p53: E180R

PubMed Link: 34907344

Variant Present in the following documents:

• Main text
• 41388_2021_Article_2141.pdf

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Rely on Each Other: DNA Binding Cooperativity Shapes p53 Functions in Tumor Suppression and Cancer Therapy.

Cancers

Timofeev, Oleg O; Stiewe, Thorsten T

Publication Date: 2021-05-17

Variant appearance in text: p53: E180R

PubMed Link: 34067731

Variant Present in the following documents:

• Main text
• cancers-13-02422.pdf

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Sphingolipids and the link between alcohol and cancer.

Chemico-Biological Interactions

Barron, Keri A KA; Jeffries, Kristen A KA; Krupenko, Natalia I NI

Publication Date: 2020-05-01

Variant appearance in text: p53: E180R

PubMed Link: 32171848

Variant Present in the following documents:

• Main text

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Putting p53 in Context.

Cell

Kastenhuber, Edward R ER; Lowe, Scott W SW

Publication Date: 2017-09-07

Variant appearance in text: p53: E180R

PubMed Link: 28886379

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• Main text

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The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression.

Cold Spring Harbor Perspectives In Medicine

Chen, Jiandong J

Publication Date: 2016-03-01

Variant appearance in text: p53: E180R

PubMed Link: 26931810

Variant Present in the following documents:

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The p53 C terminus controls site-specific DNA binding and promotes structural changes within the central DNA binding domain.

Molecular Cell

Laptenko, Oleg O; Shiff, Idit I; Freed-Pastor, Will W; Zupnick, Andrew A; Mattia, Melissa M; Freulich, Ella E; Shamir, Inbal I; Kadouri, Noam N; Kahan, Tamar T; Manfredi, James J; Simon, Itamar I; Prives, Carol C

Publication Date: 2015-03-19

Variant appearance in text: p53: E180R

PubMed Link: 25794615

Variant Present in the following documents:

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Unravelling mechanisms of p53-mediated tumour suppression.

Nature Reviews. Cancer

Bieging, Kathryn T KT; Mello, Stephano Spano SS; Attardi, Laura D LD

Publication Date: 2014-05

Variant appearance in text: p53: E180R

PubMed Link: 24739573

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Illuminating p53 function in cancer with genetically engineered mouse models.

Seminars In Cell & Developmental Biology

Garcia, Patty B PB; Attardi, Laura D LD

Publication Date: 2014-03

Variant appearance in text: p53: E180R

PubMed Link: 24394915

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Characterization of the p53 cistrome--DNA binding cooperativity dissects p53's tumor suppressor functions.

Plos Genetics

Schlereth, Katharina K; Heyl, Charlotte C; Krampitz, Anna-Maria AM; Mernberger, Marco M; Finkernagel, Florian F; Scharfe, Maren M; Jarek, Michael M; Leich, Ellen E; Rosenwald, Andreas A; Stiewe, Thorsten T

Publication Date: 2013

Variant appearance in text: p53: E180R

PubMed Link: 23966881

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Life or death: p53-induced apoptosis requires DNA binding cooperativity.

Cell Cycle (Georgetown, Tex.)

Schlereth, Katharina K; Charles, Joël P JP; Bretz, Anne C AC; Stiewe, Thorsten T

Publication Date: 2010-10-15

Variant appearance in text: p53: E180R

PubMed Link: 20948308

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