Variant ID: 17-7578406-C-T

NM_000546.5(TP53):c.524G>A;(p.R175H)

This variant was identified in 2000 publications

View GRCh38 version.




Publications:


When PIP2 Meets p53: Nuclear Phosphoinositide Signaling in the DNA Damage Response.

Frontiers In Cell And Developmental Biology
Wang, Yu-Hsiu YH; Sheetz, Michael P MP
Publication Date: 2022

Variant appearance in text: p53: R175H
PubMed Link: 35646908
Variant Present in the following documents:
  • Main text
  • fcell-10-903994.pdf
View BVdb publication page



p53N236S Activates Autophagy in Response to Hypoxic Stress Induced by DFO.

Genes
Gao, Kang K; Zong, Huanhuan H; Hou, Kailong K; Zhang, Yanduo Y; Zhang, Ruyi R; Zhao, Dan D; Guo, Xin X; Luo, Ying Y; Jia, Shuting S
Publication Date: 2022-04-26

Variant appearance in text: p53: R175H
PubMed Link: 35627147
Variant Present in the following documents:
  • Main text
  • genes-13-00763.pdf
View BVdb publication page



Preclinical Head and Neck Squamous Cell Carcinoma Models for Combined Targeted Therapy Approaches.

Cancers
Schoenwaelder, Nina N; Krause, Mareike M; Freitag, Thomas T; Schneider, Björn B; Zonnur, Sarah S; Zimpfer, Annette A; Becker, Anne Sophie AS; Salewski, Inken I; Strüder, Daniel Fabian DF; Lemcke, Heiko H; Grosse-Thie, Christina C; Junghanss, Christian C; Maletzki, Claudia C
Publication Date: 2022-05-18

Variant appearance in text: TP53: R175H
PubMed Link: 35626088
Variant Present in the following documents:
  • cancers-14-02484.pdf
View BVdb publication page



Are We Moving the Needle for Patients with TP53-Mutated Acute Myeloid Leukemia?

Cancers
Shallis, Rory M RM; Bewersdorf, Jan P JP; Stahl, Maximilian F MF; Halene, Stephanie S; Zeidan, Amer M AM
Publication Date: 2022-05-14

Variant appearance in text: TP53: R175H
PubMed Link: 35626039
Variant Present in the following documents:
  • Main text
  • cancers-14-02434.pdf
View BVdb publication page



Pathophysiologic and clinical implications of molecular profiles resultant from deletion 5q.

Ebiomedicine
Adema, Vera V; Palomo, Laura L; Walter, Wencke W; Mallo, Mar M; Hutter, Stephan S; La Framboise, Thomas T; Arenillas, Leonor L; Meggendorfer, Manja M; Radivoyevitch, Tomas T; Xicoy, Blanca B; Pellagatti, Andrea A; Haferlach, Claudia C; Boultwood, Jacqueline J; Kern, Wolfgang W; Visconte, Valeria V; Sekeres, Mikkael M; Barnard, John J; Haferlach, Torsten T; Solé, Francesc F; Maciejewski, Jaroslaw P JP
Publication Date: 2022-05-23

Variant appearance in text: TP53: 524G>A; Arg175His
PubMed Link: 35617825
Variant Present in the following documents:
  • mmc3.xlsx
View BVdb publication page



Synthetic lethality between TP53 and ENDOD1.

Nature Communications
Tang, Zizhi Z; Zeng, Ming M; Wang, Xiaojun X; Guo, Chang C; Yue, Peng P; Zhang, Xiaohu X; Lou, Huiqiang H; Chen, Jun J; Mu, Dezhi D; Kong, Daochun D; Carr, Antony M AM; Liu, Cong C
Publication Date: 2022-05-23

Variant appearance in text: TP53: R175H
PubMed Link: 35606358
Variant Present in the following documents:
  • Main text
  • 41467_2022_30311_MOESM1_ESM.pdf
  • 41467_2022_Article_30311.pdf
View BVdb publication page



Distinct landscapes of deleterious variants in DNA damage repair system in ethnic human populations.

Life Science Alliance
Qin, Zixin Z; Huang, Teng T; Guo, Maoni M; Wang, San Ming SM
Publication Date: 2022-09

Variant appearance in text: TP53: 524G>A; Arg175His; rs28934578
PubMed Link: 35595529
Variant Present in the following documents:
  • LSA-2021-01319_TableS1.xlsx
  • LSA-2021-01319_TableS3.xlsx
View BVdb publication page



Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients.

Nature Communications
Hassin, Ori O; Nataraj, Nishanth Belugali NB; Shreberk-Shaked, Michal M; Aylon, Yael Y; Yaeger, Rona R; Fontemaggi, Giulia G; Mukherjee, Saptaparna S; Maddalena, Martino M; Avioz, Adi A; Iancu, Ortal O; Mallel, Giuseppe G; Gershoni, Anat A; Grosheva, Inna I; Feldmesser, Ester E; Ben-Dor, Shifra S; Golani, Ofra O; Hendel, Ayal A; Blandino, Giovanni G; Kelsen, David D; Yarden, Yosef Y; Oren, Moshe M
Publication Date: 2022-05-19

Variant appearance in text: p53: R175H
PubMed Link: 35589715
Variant Present in the following documents:
  • Main text
  • 41467_2022_30481_MOESM2_ESM.pdf
  • 41467_2022_Article_30481.pdf
  • 41467_2022_30481_MOESM1_ESM.pdf
View BVdb publication page



Homologous recombination deficiency in diverse cancer types and its correlation with platinum chemotherapy efficiency in ovarian cancer.

Bmc Cancer
Wen, Hao H; Feng, Zheng Z; Ma, Yutong Y; Liu, Rui R; Ou, Qiuxiang Q; Guo, Qinhao Q; Shen, Yi Y; Wu, Xue X; Shao, Yang Y; Bao, Hua H; Wu, Xiaohua X
Publication Date: 2022-05-16

Variant appearance in text: TP53: 524G>A; R175H
PubMed Link: 35578198
Variant Present in the following documents:
  • 12885_2022_9602_MOESM9_ESM.xlsx
View BVdb publication page



Liquid Biopsy in Squamous Cell Carcinoma of the Esophagus and of the Head and Neck.

Frontiers In Medicine
Iacob, Razvan R; Mandea, Matei M; Iacob, Speranta S; Pietrosanu, Catalina C; Paul, Doru D; Hainarosie, Razvan R; Gheorghe, Cristian C
Publication Date: 2022

Variant appearance in text: TP53: R175H
PubMed Link: 35572996
Variant Present in the following documents:
  • fmed-09-827297.pdf
View BVdb publication page



T Cell Defects: New Insights Into the Primary Resistance Factor to CD19/CD22 Cocktail CAR T-Cell Immunotherapy in Diffuse Large B-Cell Lymphoma.

Frontiers In Immunology
Wang, Jiachen J; Shen, Kefeng K; Mu, Wei W; Li, Weigang W; Zhang, Meilan M; Zhang, Wei W; Li, Zhe Z; Ge, Tong T; Zhu, Zhoujie Z; Zhang, Shangkun S; Chen, Caixia C; Xing, Shugang S; Zhu, Li L; Chen, Liting L; Wang, Na N; Huang, Liang L; Li, Dengju D; Xiao, Min M; Zhou, Jianfeng J
Publication Date: 2022

Variant appearance in text: TP53: 524G>A; Arg175His; rs28934578
PubMed Link: 35572515
Variant Present in the following documents:
  • Table_2.xlsx
View BVdb publication page



mRNA Subtype of Cancer-Associated Fibroblasts Significantly Affects Key Characteristics of Head and Neck Cancer Cells.

Cancers
Peltanová, Barbora B; Holcová Polanská, Hana H; Raudenská, Martina M; Balvan, Jan J; Navrátil, Jiří J; Vičar, Tomáš T; Gumulec, Jaromír J; Čechová, Barbora B; Kräter, Martin M; Guck, Jochen J; Kalfeřt, David D; Grega, Marek M; Plzák, Jan J; Betka, Jan J; Masařík, Michal M
Publication Date: 2022-05-03

Variant appearance in text: p53: R175H
PubMed Link: 35565415
Variant Present in the following documents:
  • cancers-14-02286.pdf
View BVdb publication page



Space- and Time-Resolved Metabolomics of a High-Grade Serous Ovarian Cancer Mouse Model.

Cancers
Sah, Samyukta S; Ma, Xin X; Botros, Andro A; Gaul, David A DA; Yun, Sylvia R SR; Park, Eun Young EY; Kim, Olga O; Moore, Samuel G SG; Kim, Jaeyeon J; Fernández, Facundo M FM
Publication Date: 2022-04-30

Variant appearance in text: p53: R175H
PubMed Link: 35565391
Variant Present in the following documents:
  • cancers-14-02262.pdf
View BVdb publication page



The Role of E3 Ligase Pirh2 in Disease.

Cells
Daks, Alexandra A; Fedorova, Olga O; Parfenyev, Sergey S; Nevzorov, Ivan I; Shuvalov, Oleg O; Barlev, Nickolai A NA
Publication Date: 2022-04-30

Variant appearance in text: p53: R175H
PubMed Link: 35563824
Variant Present in the following documents:
  • cells-11-01515.pdf
View BVdb publication page



Inflammation: A New Look at an Old Problem.

International Journal Of Molecular Sciences
Gusev, Evgenii E; Zhuravleva, Yulia Y
Publication Date: 2022-04-21

Variant appearance in text: p53: R175H
PubMed Link: 35562986
Variant Present in the following documents:
  • ijms-23-04596.pdf
View BVdb publication page



Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways.

Nature Communications
Zhang, Yiqun Y; Chen, Fengju F; Chandrashekar, Darshan S DS; Varambally, Sooryanarayana S; Creighton, Chad J CJ
Publication Date: 2022-05-13

Variant appearance in text: p53: R175H
PubMed Link: 35562349
Variant Present in the following documents:
  • 41467_2022_30342_MOESM4_ESM.xlsx
View BVdb publication page



Relevance of Amorphous and Amyloid-Like Aggregates of the p53 Core Domain to Loss of its DNA-Binding Activity.

Frontiers In Molecular Biosciences
Hibino, Emi E; Tenno, Takeshi T; Hiroaki, Hidekazu H
Publication Date: 2022

Variant appearance in text: p53: R175H
PubMed Link: 35558561
Variant Present in the following documents:
  • fmolb-09-869851.pdf
View BVdb publication page



Fundamental immune-oncogenicity trade-offs define driver mutation fitness.

Nature
Hoyos, David D; Zappasodi, Roberta R; Schulze, Isabell I; Sethna, Zachary Z; de Andrade, Kelvin César KC; Bajorin, Dean F DF; Bandlamundi, Chaitanya C; Callahan, Margaret K MK; Funt, Samuel A SA; Hadrup, Sine R SR; Holm, Jeppe S JS; Rosenberg, Jonathan E JE; Shah, Sohrab P SP; Vázquez-García, Ignacio I; Weigelt, Britta B; Wu, Michelle M; Zamarin, Dmitriy D; Campitelli, Laura F LF; Osborne, Edward J EJ; Klinger, Mark M; Robins, Harlan S HS; Khincha, Payal P PP; Savage, Sharon A SA; Balachandran, Vinod P VP; Wolchok, Jedd D JD; Hellmann, Matthew D MD; Merghoub, Taha T; Levine, Arnold J AJ; Łuksza, Marta M; Greenbaum, Benjamin D BD
Publication Date: 2022-05-11

Variant appearance in text: p53: R175H
PubMed Link: 35545680
Variant Present in the following documents:
  • Main text
  • 41586_2022_4696_MOESM3_ESM.pdf
  • 41586_2022_Article_4696.pdf
View BVdb publication page



Mutual exclusivity of ESR1 and TP53 mutations in endocrine resistant metastatic breast cancer.

Npj Breast Cancer
Li, Zheqi Z; Spoelstra, Nicole S NS; Sikora, Matthew J MJ; Sams, Sharon B SB; Elias, Anthony A; Richer, Jennifer K JK; Lee, Adrian V AV; Oesterreich, Steffi S
Publication Date: 2022-05-10

Variant appearance in text: p53: R175H
PubMed Link: 35538119
Variant Present in the following documents:
  • 41523_2022_Article_426.pdf
  • 41523_2022_426_MOESM1_ESM.pdf
View BVdb publication page



Identification of biomarkers of response to preoperative talazoparib monotherapy in treatment naïve gBRCA+ breast cancers.

Npj Breast Cancer
Liu, Xuan X; Ge, Zhongqi Z; Yang, Fei F; Contreras, Alejandro A; Lee, Sanghoon S; White, Jason B JB; Lu, Yiling Y; Labrie, Marilyne M; Arun, Banu K BK; Moulder, Stacy L SL; Mills, Gordon B GB; Piwnica-Worms, Helen H; Litton, Jennifer K JK; Chang, Jeffrey T JT
Publication Date: 2022-05-10

Variant appearance in text: TP53: R175H
PubMed Link: 35538088
Variant Present in the following documents:
  • 41523_2022_Article_427.pdf
View BVdb publication page



Paclitaxel and cisplatin with or without cetuximab in metastatic esophageal squamous cell carcinoma: a randomized, multicenter phase II trial.

Innovation (Cambridge (Mass.))
Lu, Zhihao Z; Zhang, Yanqiao Y; Fan, Qingxia Q; Pan, Yueyin Y; Jiang, Da D; Lu, Ping P; Zhang, Jingdong J; Yuan, Xianglin X; Feng, Jifeng J; Yang, Shujun S; Yue, Wenbin W; Zhao, Lin L; Xu, Yunhua Y; Luo, Jinhua J; Shen, Lin L
Publication Date: 2022-05-10

Variant appearance in text: TP53: 524G>A; R175H
PubMed Link: 35509869
Variant Present in the following documents:
  • mmc2.xlsx
View BVdb publication page



Establishment of patient-derived organoids and a characterization-based drug discovery platform for treatment of pancreatic cancer.

Bmc Cancer
Watanabe, Sadanori S; Yogo, Akitada A; Otsubo, Tsuguteru T; Umehara, Hiroki H; Oishi, Jun J; Kodo, Toru T; Masui, Toshihiko T; Takaishi, Shigeo S; Seno, Hiroshi H; Uemoto, Shinji S; Hatano, Etsuro E
Publication Date: 2022-05-03

Variant appearance in text: rs28934578
PubMed Link: 35505283
Variant Present in the following documents:
  • 12885_2022_9619_MOESM1_ESM.xlsx
View BVdb publication page



p53 and Zinc: A Malleable Relationship.

Frontiers In Molecular Biosciences
Ha, Jeung-Hoi JH; Prela, Orjola O; Carpizo, Darren R DR; Loh, Stewart N SN
Publication Date: 2022

Variant appearance in text: p53: R175H
PubMed Link: 35495631
Variant Present in the following documents:
  • fmolb-09-895887.pdf
View BVdb publication page



Targeting TP53-Mutated Acute Myeloid Leukemia: Research and Clinical Developments.

Oncotargets And Therapy
Granowicz, Eric M EM; Jonas, Brian A BA
Publication Date: 2022

Variant appearance in text: TP53: R175H
PubMed Link: 35479302
Variant Present in the following documents:
  • ott-15-423.pdf
View BVdb publication page



Germline MBD4 deficiency causes a multi-tumor predisposition syndrome.

American Journal Of Human Genetics
Palles, Claire C; West, Hannah D HD; Chew, Edward E; Galavotti, Sara S; Flensburg, Christoffer C; Grolleman, Judith E JE; Jansen, Erik A M EAM; Curley, Helen H; Chegwidden, Laura L; Arbe-Barnes, Edward H EH; Lander, Nicola N; Truscott, Rebekah R; Pagan, Judith J; Bajel, Ashish A; Sherwood, Kitty K; Martin, Lynn L; Thomas, Huw H; Georgiou, Demetra D; Fostira, Florentia F; Goldberg, Yael Y; Adams, David J DJ; van der Biezen, Simone A M SAM; Christie, Michael M; Clendenning, Mark M; Thomas, Laura E LE; Deltas, Constantinos C; Dimovski, Aleksandar J AJ; Dymerska, Dagmara D; Lubinski, Jan J; Mahmood, Khalid K; van der Post, Rachel S RS; Sanders, Mathijs M; Weitz, Jürgen J; Taylor, Jenny C JC; Turnbull, Clare C; Vreede, Lilian L; van Wezel, Tom T; Whalley, Celina C; Arnedo-Pac, Claudia C; Caravagna, Giulio G; Cross, William W; Chubb, Daniel D; Frangou, Anna A; Gruber, Andreas J AJ; Kinnersley, Ben B; Noyvert, Boris B; Church, David D; Graham, Trevor T; Houlston, Richard R; Lopez-Bigas, Nuria N; Sottoriva, Andrea A; Wedge, David D; , ; , ; , ; Jenkins, Mark A MA; Kuiper, Roland P RP; Roberts, Andrew W AW; Cheadle, Jeremy P JP; Ligtenberg, Marjolijn J L MJL; Hoogerbrugge, Nicoline N; Koelzer, Viktor H VH; Rivas, Andres Dacal AD; Winship, Ingrid M IM; Ponte, Clara Ruiz CR; Buchanan, Daniel D DD; Power, Derek G DG; Green, Andrew A; Tomlinson, Ian P M IPM; Sampson, Julian R JR; Majewski, Ian J IJ; de Voer, Richarda M RM
Publication Date: 2022-04-20

Variant appearance in text: TP53: R175H
PubMed Link: 35460607
Variant Present in the following documents:
  • mmc2.xlsx
View BVdb publication page



TCRP1 activated by mutant p53 promotes NSCLC proliferation via inhibiting FOXO3a.

Oncogenesis
Liu, Hao H; Jia, Xiaoting X; Luo, Kai K; Chen, Xiangzhou X; Zhang, Zhijie Z; Chen, Danyang D; Gu, Yixue Y; He, Zhimin Z; Zheng, Guopei G
Publication Date: 2022-04-22

Variant appearance in text: p53: R175H
PubMed Link: 35459265
Variant Present in the following documents:
  • 41389_2022_Article_392.pdf
View BVdb publication page



Mixed Neuroendocrine Non-Neuroendocrine Neoplasms of the Gastrointestinal Tract: A Case Series.

Healthcare (Basel, Switzerland)
Guerrera, Luigi Pio LP; Suarato, Gabriella G; Napolitano, Rossella R; Perrone, Alessandra A; Caputo, Vincenza V; Ventriglia, Anna A; Martini, Giulia G; Della Corte, Carminia Maria CM; Orditura, Michele M; Martinelli, Erika E; Ciardiello, Fortunato F; Montella, Marco M; Franco, Renato R; Troiani, Teresa T; Napolitano, Stefania S
Publication Date: 2022-04-11

Variant appearance in text: TP53: R175H
PubMed Link: 35455885
Variant Present in the following documents:
  • healthcare-10-00708.pdf
View BVdb publication page



Advanced Strategies for Therapeutic Targeting of Wild-Type and Mutant p53 in Cancer.

Biomolecules
Zhang, Shengliang S; Carlsen, Lindsey L; Hernandez Borrero, Liz L; Seyhan, Attila A AA; Tian, Xiaobing X; El-Deiry, Wafik S WS
Publication Date: 2022-04-06

Variant appearance in text: p53: R175H
PubMed Link: 35454137
Variant Present in the following documents:
  • biomolecules-12-00548.pdf
View BVdb publication page



Integrated profiling of human pancreatic cancer organoids reveals chromatin accessibility features associated with drug sensitivity.

Nature Communications
Shi, Xiaohan X; Li, Yunguang Y; Yuan, Qiuyue Q; Tang, Shijie S; Guo, Shiwei S; Zhang, Yehan Y; He, Juan J; Zhang, Xiaoyu X; Han, Ming M; Liu, Zhuang Z; Zhu, Yiqin Y; Gao, Suizhi S; Wang, Huan H; Xu, Xiongfei X; Zheng, Kailian K; Jing, Wei W; Chen, Luonan L; Wang, Yong Y; Jin, Gang G; Gao, Dong D
Publication Date: 2022-04-21

Variant appearance in text: TP53: R175H
PubMed Link: 35449156
Variant Present in the following documents:
  • 41467_2022_29857_MOESM5_ESM.xlsx
View BVdb publication page



5-Hydroxymethylcytosine (5hmC) at or near cancer mutation hot spots as potential targets for early cancer detection.

Bmc Research Notes
Lu, Michael J MJ; Lu, Yabin Y
Publication Date: 2022-04-21

Variant appearance in text: TP53: 524G>A; R175H
PubMed Link: 35449110
Variant Present in the following documents:
  • 13104_2022_Article_6028.pdf
View BVdb publication page



CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition.

Nature
Gallo, David D; Young, Jordan T F JTF; Fourtounis, Jimmy J; Martino, Giovanni G; Álvarez-Quilón, Alejandro A; Bernier, Cynthia C; Duffy, Nicole M NM; Papp, Robert R; Roulston, Anne A; Stocco, Rino R; Szychowski, Janek J; Veloso, Artur A; Alam, Hunain H; Baruah, Prasamit S PS; Fortin, Alexanne Bonneau AB; Bowlan, Julian J; Chaudhary, Natasha N; Desjardins, Jessica J; Dietrich, Evelyne E; Fournier, Sara S; Fugère-Desjardins, Chloe C; Goullet de Rugy, Theo T; Leclaire, Marie-Eve ME; Liu, Bingcan B; Bhaskaran, Vivek V; Mamane, Yael Y; Melo, Henrique H; Nicolas, Olivier O; Singhania, Akul A; Szilard, Rachel K RK; Tkáč, Ján J; Yin, Shou Yun SY; Morris, Stephen J SJ; Zinda, Michael M; Marshall, C Gary CG; Durocher, Daniel D
Publication Date: 2022-04-20

Variant appearance in text: TP53: R175H
PubMed Link: 35444283
Variant Present in the following documents:
  • 41586_2022_Article_4638.pdf
View BVdb publication page



PIM1 genetic alterations associated with distinct molecular profiles, phenotypes and drug responses in diffuse large B-cell lymphoma.

Clinical And Translational Medicine
Zhang, Huilai H; Lu, Yaxiao Y; Zhang, Tingting T; Guan, Qingpei Q; Wang, Xiaoxuan X; Guo, Yixian Y; Li, Lanfang L; Qiu, Lihua L; Qian, Zhengzi Z; Zhou, Shiyong S; Gong, Wenchen W; Meng, Bin B; Ren, Xiubao X; Wang, Xianhuo X
Publication Date: 2022-04

Variant appearance in text: TP53: R175H
PubMed Link: 35415904
Variant Present in the following documents:
  • CTM2-12-e808-s003.xlsx
View BVdb publication page



Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune escape through PHLPP2/AKT/PD-L1 pathway.

International Journal Of Biological Sciences
Liu, Nannan N; Jiang, Xinxiu X; Guo, Leiming L; Zhang, Chuchu C; Jiang, Meimei M; Sun, Zhuoran Z; Zhang, Yizheng Y; Mi, Wunan W; Li, Jiehan J; Fu, Yang Y; Wang, Feng F; Zhang, Lingling L; Zhang, Yingjie Y
Publication Date: 2022

Variant appearance in text: TP53: R175H
PubMed Link: 35414774
Variant Present in the following documents:
  • ijbsv18p2419s1.pdf
  • ijbsv18p2419.pdf
View BVdb publication page



Growth factor independence underpins a paroxysmal, aggressive Wnt5aHigh/EphA2Low phenotype in glioblastoma stem cells, conducive to experimental combinatorial therapy.

Journal Of Experimental & Clinical Cancer Research : Cr
Trivieri, Nadia N; Visioli, Alberto A; Mencarelli, Gandino G; Cariglia, Maria Grazia MG; Marongiu, Laura L; Pracella, Riccardo R; Giani, Fabrizio F; Soriano, Amata Amy AA; Barile, Chiara C; Cajola, Laura L; Copetti, Massimiliano M; Palumbo, Orazio O; Legnani, Federico F; DiMeco, Francesco F; Gorgoglione, Leonardo L; Vescovi, Angelo L AL; Binda, Elena E
Publication Date: 2022-04-12

Variant appearance in text: TP53: R175H; rs28934578
PubMed Link: 35414102
Variant Present in the following documents:
  • 13046_2022_2333_MOESM3_ESM.xlsx
  • 13046_2022_2333_MOESM4_ESM.xlsx
View BVdb publication page



Germline Variants in Cancer Genes from Young Breast Cancer Mexican Patients.

Cancers
Gómez-Flores-Ramos, Liliana L; Barraza-Arellano, Angélica Leticia AL; Mohar, Alejandro A; Trujillo-Martínez, Miguel M; Grimaldo, Lizbeth L; Ortiz-Lopez, Rocío R; Treviño, Víctor V
Publication Date: 2022-03-24

Variant appearance in text: TP53: R175H
PubMed Link: 35406420
Variant Present in the following documents:
  • cancers-14-01647.pdf
View BVdb publication page



Inhibiting the Priming for Cancer in Li-Fraumeni Syndrome.

Cancers
Pantziarka, Pan P; Blagden, Sarah S
Publication Date: 2022-03-23

Variant appearance in text: p53: R175H
PubMed Link: 35406393
Variant Present in the following documents:
  • cancers-14-01621.pdf
View BVdb publication page



Somatic LINE-1 promoter acquisition drives oncogenic FOXR2 activation in pediatric brain tumor.

Acta Neuropathologica
Flasch, Diane A DA; Chen, Xiaolong X; Ju, Bensheng B; Li, Xiaoyu X; Dalton, James J; Mulder, Heather L HL; Easton, John J; Wang, Lu L; Baker, Suzanne J SJ; Chiang, Jason J; Zhang, Jinghui J
Publication Date: 2022-04-11

Variant appearance in text: TP53: R175H
PubMed Link: 35403869
Variant Present in the following documents:
  • 401_2022_Article_2420.pdf
View BVdb publication page



Proof-of-Concept Pilot Study on Comprehensive Spatiotemporal Intra-Patient Heterogeneity for Colorectal Cancer With Liver Metastasis.

Frontiers In Oncology
Kyrochristos, Ioannis D ID; Glantzounis, Georgios K GK; Goussia, Anna A; Eliades, Alexia A; Achilleos, Achilleas A; Tsangaras, Kyriakos K; Hadjidemetriou, Irene I; Elpidorou, Marilena M; Ioannides, Marios M; Koumbaris, George G; Mitsis, Michail M; Patsalis, Philippos C PC; Roukos, Dimitrios D
Publication Date: 2022

Variant appearance in text: TP53: 524G>A
PubMed Link: 35402285
Variant Present in the following documents:
  • Table_1.xlsx
View BVdb publication page



Clinicopathologic and Genomic Features in Triple-Negative Breast Cancer Between Special and No-Special Morphologic Pattern.

Frontiers In Oncology
Li, Ying-Zi YZ; Chen, Bo B; Lin, Xiao-Yi XY; Zhang, Guo-Chun GC; Lai, Jian-Guo JG; Li, Cheukfai C; Lin, Jia-Li JL; Guo, Li-Ping LP; Xiao, Wei-Kai WK; Mok, Hsiaopei H; Ren, Chong-Yang CY; Wen, Ling-Zhu LZ; Cao, Fang-Rong FR; Lin, Xin X; Qi, Xiao-Fang XF; Liu, Yang Y; Liao, Ning N
Publication Date: 2022

Variant appearance in text: TP53: R175H
PubMed Link: 35402236
Variant Present in the following documents:
  • fonc-12-830124.pdf
View BVdb publication page



Integrated genomic analyses identify high-risk factors and actionable targets in T-cell acute lymphoblastic leukemia.

Blood Science (Baltimore, Md.)
Zhu, Haichuan H; Dong, Bingjie B; Zhang, Yingchi Y; Wang, Mei M; Rao, Jianan J; Cui, Bowen B; Liu, Yu Y; Jiang, Qian Q; Wang, Weitao W; Yang, Lu L; Yu, Anqi A; Li, Zongru Z; Liu, Chao C; Zhang, Leping L; Huang, Xiaojun X; Zhu, Xiaofan X; Wu, Hong H
Publication Date: 2022-01

Variant appearance in text: TP53: R175H
PubMed Link: 35399540
Variant Present in the following documents:
  • bls-4-16-s005.xlsx
View BVdb publication page



Phase 1b study of berzosertib and cisplatin in patients with advanced triple-negative breast cancer.

Npj Breast Cancer
Telli, Melinda L ML; Tolaney, Sara M SM; Shapiro, Geoffrey I GI; Middleton, Mark M; Lord, Simon R SR; Arkenau, Hendrik Tobias HT; Tutt, Andrew A; Abramson, Vandana V; Dean, Emma E; Haddad, Tufia C TC; Wesolowski, Robert R; Ferrer-Playan, Jordi J; Goddemeier, Thomas T; Grombacher, Thomas T; Dong, Jennifer J; Fleuranceau-Morel, Patricia P; Diaz-Padilla, Ivan I; Plummer, Ruth R
Publication Date: 2022-04-07

Variant appearance in text: TP53: R175H
PubMed Link: 35393425
Variant Present in the following documents:
  • 41523_2022_406_MOESM1_ESM.pdf
View BVdb publication page



Deciphering the Increased Prevalence of TP53 Mutations in Metastatic Prostate Cancer.

Cancer Informatics
Zhang, Wensheng W; Dong, Yan Y; Sartor, Oliver O; Zhang, Kun K
Publication Date: 2022

Variant appearance in text: TP53: 524G>A
PubMed Link: 35392296
Variant Present in the following documents:
  • 10.1177_11769351221087046.pdf
View BVdb publication page



Genomic clonal evolution correlated with phenotype and prognosis in gastric cancer.

Clinical And Translational Medicine
Ge, Jie J; Li, Xuan X; Deng, Zhenghao Z; Gao, Xuan X; Liu, Yaoyao Y; Xiong, Xingui X; Zhao, Xianhui X; Peng, Huan H; Yi, Xin X; Xia, Xuefeng X; Chen, Zihua Z; Li, Lifeng L; Zhou, Haiyan H; Liu, Heli H
Publication Date: 2022-04

Variant appearance in text: TP53: 524G>A; R175H
PubMed Link: 35384329
Variant Present in the following documents:
  • CTM2-12-e799-s006.xlsx
View BVdb publication page



A molecular approach integrating genomic and DNA methylation profiling for tissue of origin identification in lung-specific cancer of unknown primary.

Journal Of Translational Medicine
Chen, Kaiyan K; Zhang, Fanrong F; Yu, Xiaoqing X; Huang, Zhiyu Z; Gong, Lei L; Xu, Yanjun Y; Li, Hui H; Yu, Sizhe S; Fan, Yun Y
Publication Date: 2022-04-05

Variant appearance in text: TP53: R175H
PubMed Link: 35382836
Variant Present in the following documents:
  • 12967_2022_Article_3362.pdf
View BVdb publication page



Mutant p53: it's not all one and the same.

Cell Death And Differentiation
Kennedy, Margaret C MC; Lowe, Scott W SW
Publication Date: 2022-03-31

Variant appearance in text: p53: R175H
PubMed Link: 35361963
Variant Present in the following documents:
  • 41418_2022_Article_989.pdf
View BVdb publication page



Clinical utility of comprehensive genomic profiling in Japan: Result of PROFILE-F study.

Plos One
Aoyagi, Yasuko Y; Kano, Yoshihito Y; Tohyama, Kohki K; Matsudera, Shotaro S; Kumaki, Yuichi Y; Takahashi, Kenta K; Mitsumura, Takahiro T; Harada, Yohei Y; Sato, Akemi A; Nakamura, Hideaki H; Sueoka, Eisaburo E; Aragane, Naoko N; Kimura, Koichiro K; Onishi, Iichiro I; Takemoto, Akira A; Akahoshi, Keiichi K; Ono, Hiroaki H; Ishikawa, Toshiaki T; Tokunaga, Masanori M; Nakagawa, Tsuyoshi T; Oshima, Noriko N; Nakamura, Reiko R; Takagi, Masatoshi M; Asakage, Takahiro T; Uetake, Hiroyuki H; Tanabe, Minoru M; Miyake, Satoshi S; Kinugasa, Yusuke Y; Ikeda, Sadakatsu S
Publication Date: 2022

Variant appearance in text: TP53: R175H
PubMed Link: 35358259
Variant Present in the following documents:
  • pone.0266112.s001.xlsx
View BVdb publication page



Non-human primate papillomavirus E6-mediated p53 degradation reveals ancient evolutionary adaptation of carcinogenic phenotype to host niche.

Plos Pathogens
Long, Teng T; Burk, Robert D RD; Chan, Paul K S PKS; Chen, Zigui Z
Publication Date: 2022-03-25

Variant appearance in text: p53: R175H
PubMed Link: 35333912
Variant Present in the following documents:
  • ppat.1010444.pdf
View BVdb publication page



TP53 Expression and Mutational Analysis in Hematological Malignancy in Jeddah, Saudi Arabia.

Diagnostics (Basel, Switzerland)
Alkhatabi, Heba H; Yasin, Elrashed B EB; Mirza, Zeenat Z; Alserihi, Raed R; Felimban, Raed R; Elaimi, Aisha A; Shaabad, Manal M; Alharbi, Lina L; Ahmed, Hameeda H; Alameer, Abdulrahman M AM; Mathkoor, Abdullah Ebraheem AE; Barefah, Ahmed Salleh AS
Publication Date: 2022-03-16

Variant appearance in text: rs28934578
PubMed Link: 35328276
Variant Present in the following documents:
  • diagnostics-12-00724.pdf
View BVdb publication page



NAMPT Inhibitor and P73 Activator Represses P53 R175H Mutated HNSCC Cell Proliferation in a Synergistic Manner.

Biomolecules
Cai, Bi-He BH; Bai, Zhi-Yu ZY; Lien, Ching-Feng CF; Yu, Si-Jie SJ; Lu, Rui-Yu RY; Wu, Ming-Han MH; Wu, Wei-Chen WC; Chen, Chia-Chi CC; Hsu, Yi-Chiang YC
Publication Date: 2022-03-12

Variant appearance in text: p53: R175H
PubMed Link: 35327630
Variant Present in the following documents:
  • biomolecules-12-00438.pdf
View BVdb publication page



Response prediction and risk stratification of patients with rectal cancer after neoadjuvant therapy through an analysis of circulating tumour DNA.

Ebiomedicine
Liu, Wenyang W; Li, Yifei Y; Tang, Yuan Y; Song, Qianqian Q; Wang, Jingjing J; Li, Ning N; Chen, Silin S; Shi, Jinming J; Wang, Shulian S; Li, Yexiong Y; Jiao, Yuchen Y; Zeng, Yixin Y; Jin, Jing J
Publication Date: 2022-03-17

Variant appearance in text: TP53: 524G>A
PubMed Link: 35306340
Variant Present in the following documents:
  • mmc3.xlsx
View BVdb publication page



Parecoxib inhibits esophageal squamous cell carcinoma progression via the PDK1-AKT pathway.

Cellular & Molecular Biology Letters
Huang, Han-Ming HM; Huang, Xiao-Yu XY; Wu, Shao-Ping SP; Chen, Can-Keng CK; He, Xin-Hua XH; Zhang, Yong-Fa YF
Publication Date: 2022-03-19

Variant appearance in text: p53: R175H
PubMed Link: 35305553
Variant Present in the following documents:
  • 11658_2022_Article_324.pdf
View BVdb publication page



Zebrafish imaging reveals TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesis.

Nature Communications
Haraoka, Yukinari Y; Akieda, Yuki Y; Nagai, Yuri Y; Mogi, Chihiro C; Ishitani, Tohru T
Publication Date: 2022-03-18

Variant appearance in text: TP53: R175H
PubMed Link: 35304872
Variant Present in the following documents:
  • 41467_2022_29061_MOESM1_ESM.pdf
  • 41467_2022_29061_MOESM2_ESM.pdf
View BVdb publication page



Dynamic changes in gene alterations during chemotherapy in metastatic castrate resistant prostate cancer.

Scientific Reports
Tan, Winston W; Zheng, Tiantian T; Wang, Amy A; Roacho, Joanna J; Thao, Seng S; Du, Pan P; Jia, Shidong S; Yu, Jianjun J; King, Bonnie L BL; Kohli, Manish M
Publication Date: 2022-03-18

Variant appearance in text: TP53: 524G>A; Arg175His
PubMed Link: 35304525
Variant Present in the following documents:
  • 41598_2022_8520_MOESM2_ESM.xlsx
View BVdb publication page



p16INK4A-deficiency predicts response to combined HER2 and CDK4/6 inhibition in HER2+ breast cancer brain metastases.

Nature Communications
Ni, Jing J; Kabraji, Sheheryar S; Xie, Shaozhen S; Wang, Yanzhi Y; Pan, Peichen P; He, Xiaofang X; Liu, Zongming Z; Leone, Jose Palbo JP; Long, Henry W HW; Brown, Myles A MA; Winer, Eric P EP; Dillon, Deborah A R DAR; Lin, Nancy U NU; Zhao, Jean J JJ
Publication Date: 2022-03-18

Variant appearance in text: TP53: R175H
PubMed Link: 35304445
Variant Present in the following documents:
  • 41467_2022_29081_MOESM3_ESM.xlsx
View BVdb publication page



A general calculus of fitness landscapes finds genes under selection in cancers.

Genome Research
Hsu, Teng-Kuei TK; Asmussen, Jennifer Kay JK; Koire, Amanda Michele AM; Choi, Byung-Kwon BK; Gadhikar, Mayur Arvind MA; Huh, Eunna E; Lin, Chih-Hsu CH; Konecki, Daniel Manuka DM; Kim, Young Won YW; Pickering, Curtis C; Kimmel, Marek M; Donehower, Lawrence Allen LA; Frederick, Mitchell Jay MJ; Myers, Jeffrey N JN; Katsonis, Panagiotis P; Lichtarge, Olivier O
Publication Date: 2022-03-17

Variant appearance in text: TP53: R175H
PubMed Link: 35301263
Variant Present in the following documents:
  • Main text
  • 916.pdf
View BVdb publication page



Perioperative Circulating Tumor DNA Enables Identification of Patients with Poor Prognosis in Upper Tract Urothelial Carcinoma.

Cancer Science
Nakano, Kosuke K; Koh, Yoko Y; Yamamichi, Gaku G; Yumiba, Satoru S; Tomiyama, Eisuke E; Matsushita, Makoto M; Hayashi, Yujiro Y; Wang, Cong C; Ishizuya, Yu Y; Yamamoto, Yoshiyuki Y; Kato, Taigo T; Hatano, Koji K; Kawashima, Atsunari A; Ujike, Takeshi T; Fujita, Kazutoshi K; Kiyotani, Kazuma K; Katayama, Kotoe K; Yamaguchi, Rui R; Imoto, Seiya S; Imamura, Ryoichi R; Nonomura, Norio N; Uemura, Motohide M
Publication Date: 2022-03-16

Variant appearance in text: TP53: R175H
PubMed Link: 35293110
Variant Present in the following documents:
  • CAS-113-1830-s004.xlsx
View BVdb publication page



Case Report Series: Aggressive HR Deficient Colorectal Cancers Related to BRCA1 Pathogenic Germline Variants.

Frontiers In Oncology
Freire, Maria Valeria MV; Martin, Marie M; Thissen, Romain R; Van Marcke, Cédric C; Segers, Karin K; Sépulchre, Edith E; Leroi, Natacha N; Lété, Céline C; Fasquelle, Corinne C; Radermacher, Jean J; Gokburun, Yeter Y; Collignon, Joelle J; Sacré, Anne A; Josse, Claire C; Palmeira, Leonor L; Bours, Vincent V
Publication Date: 2022

Variant appearance in text: TP53: 524G>A; Arg175His
PubMed Link: 35280729
Variant Present in the following documents:
  • fonc-12-835581.pdf
View BVdb publication page



The Landscape of Actionable Genomic Alterations by Next-Generation Sequencing in Tumor Tissue Versus Circulating Tumor DNA in Chinese Patients With Non-Small Cell Lung Cancer.

Frontiers In Oncology
Cai, Jun J; Jiang, Huihui H; Li, Shuqing S; Yan, Xiaoxia X; Wang, Meng M; Li, Na N; Zhu, Cuimin C; Dong, Hui H; Wang, Dongjuan D; Xu, Yue Y; Xie, Hui H; Wu, Shouxin S; Lou, Jingwei J; Zhao, Jiangman J; Li, Qingshan Q
Publication Date: 2021

Variant appearance in text: TP53: R175H
PubMed Link: 35273907
Variant Present in the following documents:
  • Table_8.xlsx
View BVdb publication page



Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications
Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L
Publication Date: 2022-03-10

Variant appearance in text: TP53: 524G>A; R175H
PubMed Link: 35273153
Variant Present in the following documents:
  • 41467_2022_28840_MOESM7_ESM.xlsx
View BVdb publication page



Identification of Neoantigens in Cancer Cells as Targets for Immunotherapy.

International Journal Of Molecular Sciences
Okada, Masahiro M; Shimizu, Kanako K; Fujii, Shin-Ichiro SI
Publication Date: 2022-02-26

Variant appearance in text: TP53: R175H
PubMed Link: 35269735
Variant Present in the following documents:
  • ijms-23-02594.pdf
View BVdb publication page



Cranberry Polyphenols in Esophageal Cancer Inhibition: New Insights.

Nutrients
Weh, Katherine M KM; Zhang, Yun Y; Howard, Connor L CL; Howell, Amy B AB; Clarke, Jennifer L JL; Kresty, Laura A LA
Publication Date: 2022-02-24

Variant appearance in text: TP53: 524G>A
PubMed Link: 35267943
Variant Present in the following documents:
  • nutrients-14-00969.pdf
View BVdb publication page



Estrogen Receptor-Beta2 (ERβ2)-Mutant p53-FOXM1 Axis: A Novel Driver of Proliferation, Chemoresistance, and Disease Progression in High Grade Serous Ovarian Cancer (HGSOC).

Cancers
Oturkar, Chetan C CC; Gandhi, Nishant N; Rao, Pramod P; Eng, Kevin H KH; Miller, Austin A; Singh, Prashant K PK; Zsiros, Emese E; Odunsi, Kunle O KO; Das, Gokul M GM
Publication Date: 2022-02-22

Variant appearance in text: p53: R175H
PubMed Link: 35267428
Variant Present in the following documents:
  • cancers-14-01120.pdf
View BVdb publication page



Characterization of disease-propagating stem cells responsible for myeloproliferative neoplasm-blast phase.

Jci Insight
Wang, Xiaoli X; Rampal, Raajit K RK; Hu, Cing Siang CS; Tripodi, Joseph J; Farnoud, Noushin N; Petersen, Bruce B; Rossi, Michael R MR; Patel, Minal M; McGovern, Erin E; Najfeld, Vesna V; Iancu-Rubin, Camelia C; Lu, Min M; Davis, Andrew A; Kremyanskaya, Marina M; Weinberg, Rona Singer RS; Mascarenhas, John J; Hoffman, Ronald R
Publication Date: 2022-03-08

Variant appearance in text: TP53: R175H
PubMed Link: 35259128
Variant Present in the following documents:
  • jciinsight-7-156534-s067.xlsx
View BVdb publication page



Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog.

Cell Death & Disease
Zhang, Qiang Q; Balourdas, Dimitrios-Ilias DI; Baron, Bruno B; Senitzki, Alon A; Haran, Tali E TE; Wiman, Klas G KG; Soussi, Thierry T; Joerger, Andreas C AC
Publication Date: 2022-03-07

Variant appearance in text: p53: R175H
PubMed Link: 35256607
Variant Present in the following documents:
  • 41419_2022_4653_MOESM1_ESM.pdf
  • 41419_2022_Article_4653.pdf
View BVdb publication page



Landscape of TP53 Alterations in Chronic Lymphocytic Leukemia via Data Mining Mutation Databases.

Frontiers In Oncology
Soussi, Thierry T; Baliakas, Panagiotis P
Publication Date: 2022

Variant appearance in text: TP53: Arg175His
PubMed Link: 35251978
Variant Present in the following documents:
  • fonc-12-808886.pdf
View BVdb publication page



Complete Response With Cetuximab-Based Treatment of Metastatic Colorectal Cancers: Two Case Reports and Literature Review.

Frontiers In Oncology
Wei, Li L; Lin, Zexiao Z; Xie, Sidong S; Ruan, Danyun D; Jiang, Wen W; Cui, Yueli Y; Liu, Sisi S; Wang, Tiantian T; Chen, Zhanhong Z; Lin, Qu Q
Publication Date: 2022

Variant appearance in text: TP53: 524G>A
PubMed Link: 35251973
Variant Present in the following documents:
  • fonc-12-798515.pdf
View BVdb publication page



Rapid recruitment of p53 to DNA damage sites directs DNA repair choice and integrity.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Wang, Yu-Hsiu YH; Ho, Teresa L F TLF; Hariharan, Anushya A; Goh, Hui Chin HC; Wong, Yao Liang YL; Verkaik, Nicole S NS; Lee, May Yin MY; Tam, Wai Leong WL; van Gent, Dik C DC; Venkitaraman, Ashok R AR; Sheetz, Michael P MP; Lane, David P DP
Publication Date: 2022-03-08

Variant appearance in text: p53: R175H
PubMed Link: 35235448
Variant Present in the following documents:
  • pnas.202113233.pdf
View BVdb publication page



Partial p53 reactivation is sufficient to induce cancer regression.

Journal Of Experimental & Clinical Cancer Research : Cr
Klimovich, Boris B; Meyer, Laura L; Merle, Nastasja N; Neumann, Michelle M; König, Alexander M AM; Ananikidis, Nikolaos N; Keber, Corinna U CU; Elmshäuser, Sabrina S; Timofeev, Oleg O; Stiewe, Thorsten T
Publication Date: 2022-03-02

Variant appearance in text: p53: R175H
PubMed Link: 35232479
Variant Present in the following documents:
  • 13046_2022_Article_2269.pdf
View BVdb publication page



T Cell Recognition of Tumor Neoantigens and Insights Into T Cell Immunotherapy.

Frontiers In Immunology
Sim, Malcolm J W MJW; Sun, Peter D PD
Publication Date: 2022

Variant appearance in text: TP53: R175H
PubMed Link: 35222422
Variant Present in the following documents:
  • fimmu-13-833017.pdf
View BVdb publication page



The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer
Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J
Publication Date: 2022-02

Variant appearance in text: TP53: Arg175His
PubMed Link: 35221333
Variant Present in the following documents:
  • 43018_2022_332_MOESM3_ESM.xlsx
View BVdb publication page



Phosphoproteomic profiling of T cell acute lymphoblastic leukemia reveals targetable kinases and combination treatment strategies.

Nature Communications
Cordo', Valentina V; Meijer, Mariska T MT; Hagelaar, Rico R; de Goeij-de Haas, Richard R RR; Poort, Vera M VM; Henneman, Alex A AA; Piersma, Sander R SR; Pham, Thang V TV; Oshima, Koichi K; Ferrando, Adolfo A AA; Zaman, Guido J R GJR; Jimenez, Connie R CR; Meijerink, Jules P P JPP
Publication Date: 2022-02-25

Variant appearance in text: TP53: R175H
PubMed Link: 35217681
Variant Present in the following documents:
  • 41467_2022_28682_MOESM4_ESM.xlsx
View BVdb publication page



Experimental Nuclear Medicine Meets Tumor Biology.

Pharmaceuticals (Basel, Switzerland)
Balber, Theresa T; Tran, Loan L; Benčurová, Katarína K; Raitanen, Julia J; Egger, Gerda G; Mitterhauser, Markus M
Publication Date: 2022-02-14

Variant appearance in text: p53: R175H
PubMed Link: 35215337
Variant Present in the following documents:
  • pharmaceuticals-15-00227.pdf
View BVdb publication page



Neoantigen: A Promising Target for the Immunotherapy of Colorectal Cancer.

Disease Markers
Zheng, Yue Y; Fu, Yang Y; Wang, Pei-Pei PP; Ding, Zhen-Yu ZY
Publication Date: 2022

Variant appearance in text: TP53: R175H
PubMed Link: 35211210
Variant Present in the following documents:
  • DM2022-8270305.pdf
View BVdb publication page



p53 Signaling on Microenvironment and Its Contribution to Tissue Chemoresistance.

Membranes
Souza, Leonel Cardozo de Menezes E LCME; Faletti, Anderson A; Veríssimo, Carla Pires CP; Stelling, Mariana Paranhos MP; Borges, Helena Lobo HL
Publication Date: 2022-02-09

Variant appearance in text: p53: R175H
PubMed Link: 35207121
Variant Present in the following documents:
  • membranes-12-00202.pdf
View BVdb publication page



Regulation of p53 Function by Formation of Non-Nuclear Heterologous Protein Complexes.

Biomolecules
Zavileyskiy, Lev L; Bunik, Victoria V
Publication Date: 2022-02-18

Variant appearance in text: p53: R175H
PubMed Link: 35204825
Variant Present in the following documents:
  • biomolecules-12-00327.pdf
View BVdb publication page



Tumor Suppressor Role of Wild-Type P53-Dependent Secretome and Its Proteomic Identification in PDAC.

Biomolecules
Butera, Giovanna G; Manfredi, Marcello M; Fiore, Alessandra A; Brandi, Jessica J; Pacchiana, Raffaella R; De Giorgis, Veronica V; Barberis, Elettra E; Vanella, Virginia V; Galasso, Marilisa M; Scupoli, Maria Teresa MT; Marengo, Emilio E; Cecconi, Daniela D; Donadelli, Massimo M
Publication Date: 2022-02-13

Variant appearance in text: p53: R175H
PubMed Link: 35204804
Variant Present in the following documents:
  • biomolecules-12-00305.pdf
View BVdb publication page



USP15 in Cancer and Other Diseases: From Diverse Functionsto Therapeutic Targets.

Biomedicines
Li, Yan-Chi YC; Cai, Song-Wang SW; Shu, Yu-Bin YB; Chen, Mei-Wan MW; Shi, Zhi Z
Publication Date: 2022-02-17

Variant appearance in text: p53: R175H
PubMed Link: 35203682
Variant Present in the following documents:
  • biomedicines-10-00474.pdf
View BVdb publication page



The therapeutic potential of RNA Polymerase I transcription inhibitor, CX-5461, in uterine leiomyosarcoma.

Investigational New Drugs
Kang, Chang-Won CW; Hannan, Katherine M KM; Blackburn, Anneke C AC; Loh, Amos H P AHP; Hong, Kuick Chik KC; Yuan, Goh Jian GJ; Hein, Nadine N; Drygin, Denis D; Hannan, Ross D RD; Coupland, Lucy A LA
Publication Date: 2022-02-24

Variant appearance in text: TP53: R175H
PubMed Link: 35201535
Variant Present in the following documents:
  • 10637_2022_Article_1222.pdf
View BVdb publication page



Recent advances in cancer immunotherapy.

Discover. Oncology
Sun, Qiang Q; Melino, Gerry G; Amelio, Ivano I; Jiang, Jingting J; Wang, Ying Y; Shi, Yufang Y
Publication Date: 2021-08-18

Variant appearance in text: TP53: Arg175His
PubMed Link: 35201440
Variant Present in the following documents:
  • 12672_2021_Article_422.pdf
View BVdb publication page



Curcumin analog HO-3867 triggers apoptotic pathways through activating JNK1/2 signalling in human oral squamous cell carcinoma cells.

Journal Of Cellular And Molecular Medicine
Chen, Chi-Wei CW; Hsieh, Ming-Ju MJ; Ju, Po-Chung PC; Hsieh, Yi-Hsien YH; Su, Chun-Wen CW; Chen, Yen-Lin YL; Yang, Shun-Fa SF; Lin, Chiao-Wen CW
Publication Date: 2022-02-21

Variant appearance in text: p53: R175H
PubMed Link: 35191177
Variant Present in the following documents:
  • JCMM-26-2273.pdf
View BVdb publication page