Publications:

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When PIP2 Meets p53: Nuclear Phosphoinositide Signaling in the DNA Damage Response.

Frontiers In Cell And Developmental Biology

Wang, Yu-Hsiu YH; Sheetz, Michael P MP

Publication Date: 2022

Variant appearance in text: p53: R175H

PubMed Link: 35646908

Variant Present in the following documents:

• Main text
• fcell-10-903994.pdf

View BVdb publication page

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p53N236S Activates Autophagy in Response to Hypoxic Stress Induced by DFO.

Genes

Gao, Kang K; Zong, Huanhuan H; Hou, Kailong K; Zhang, Yanduo Y; Zhang, Ruyi R; Zhao, Dan D; Guo, Xin X; Luo, Ying Y; Jia, Shuting S

Publication Date: 2022-04-26

Variant appearance in text: p53: R175H

PubMed Link: 35627147

Variant Present in the following documents:

• Main text
• genes-13-00763.pdf

View BVdb publication page

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Preclinical Head and Neck Squamous Cell Carcinoma Models for Combined Targeted Therapy Approaches.

Cancers

Schoenwaelder, Nina N; Krause, Mareike M; Freitag, Thomas T; Schneider, Björn B; Zonnur, Sarah S; Zimpfer, Annette A; Becker, Anne Sophie AS; Salewski, Inken I; Strüder, Daniel Fabian DF; Lemcke, Heiko H; Grosse-Thie, Christina C; Junghanss, Christian C; Maletzki, Claudia C

Publication Date: 2022-05-18

Variant appearance in text: TP53: R175H

PubMed Link: 35626088

Variant Present in the following documents:

• cancers-14-02484.pdf

View BVdb publication page

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Are We Moving the Needle for Patients with TP53-Mutated Acute Myeloid Leukemia?

Cancers

Shallis, Rory M RM; Bewersdorf, Jan P JP; Stahl, Maximilian F MF; Halene, Stephanie S; Zeidan, Amer M AM

Publication Date: 2022-05-14

Variant appearance in text: TP53: R175H

PubMed Link: 35626039

Variant Present in the following documents:

• Main text
• cancers-14-02434.pdf

View BVdb publication page

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Pathophysiologic and clinical implications of molecular profiles resultant from deletion 5q.

Ebiomedicine

Adema, Vera V; Palomo, Laura L; Walter, Wencke W; Mallo, Mar M; Hutter, Stephan S; La Framboise, Thomas T; Arenillas, Leonor L; Meggendorfer, Manja M; Radivoyevitch, Tomas T; Xicoy, Blanca B; Pellagatti, Andrea A; Haferlach, Claudia C; Boultwood, Jacqueline J; Kern, Wolfgang W; Visconte, Valeria V; Sekeres, Mikkael M; Barnard, John J; Haferlach, Torsten T; Solé, Francesc F; Maciejewski, Jaroslaw P JP

Publication Date: 2022-05-23

Variant appearance in text: TP53: 524G>A; Arg175His

PubMed Link: 35617825

Variant Present in the following documents:

• mmc3.xlsx

View BVdb publication page

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Synthetic lethality between TP53 and ENDOD1.

Nature Communications

Tang, Zizhi Z; Zeng, Ming M; Wang, Xiaojun X; Guo, Chang C; Yue, Peng P; Zhang, Xiaohu X; Lou, Huiqiang H; Chen, Jun J; Mu, Dezhi D; Kong, Daochun D; Carr, Antony M AM; Liu, Cong C

Publication Date: 2022-05-23

Variant appearance in text: TP53: R175H

PubMed Link: 35606358

Variant Present in the following documents:

• Main text
• 41467_2022_30311_MOESM1_ESM.pdf
• 41467_2022_Article_30311.pdf

View BVdb publication page

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Distinct landscapes of deleterious variants in DNA damage repair system in ethnic human populations.

Life Science Alliance

Qin, Zixin Z; Huang, Teng T; Guo, Maoni M; Wang, San Ming SM

Publication Date: 2022-09

Variant appearance in text: TP53: 524G>A; Arg175His; rs28934578

PubMed Link: 35595529

Variant Present in the following documents:

• LSA-2021-01319_TableS1.xlsx
• LSA-2021-01319_TableS3.xlsx

View BVdb publication page

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Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients.

Nature Communications

Hassin, Ori O; Nataraj, Nishanth Belugali NB; Shreberk-Shaked, Michal M; Aylon, Yael Y; Yaeger, Rona R; Fontemaggi, Giulia G; Mukherjee, Saptaparna S; Maddalena, Martino M; Avioz, Adi A; Iancu, Ortal O; Mallel, Giuseppe G; Gershoni, Anat A; Grosheva, Inna I; Feldmesser, Ester E; Ben-Dor, Shifra S; Golani, Ofra O; Hendel, Ayal A; Blandino, Giovanni G; Kelsen, David D; Yarden, Yosef Y; Oren, Moshe M

Publication Date: 2022-05-19

Variant appearance in text: p53: R175H

PubMed Link: 35589715

Variant Present in the following documents:

• Main text
• 41467_2022_30481_MOESM2_ESM.pdf
• 41467_2022_Article_30481.pdf
• 41467_2022_30481_MOESM1_ESM.pdf

View BVdb publication page

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Homologous recombination deficiency in diverse cancer types and its correlation with platinum chemotherapy efficiency in ovarian cancer.

Bmc Cancer

Wen, Hao H; Feng, Zheng Z; Ma, Yutong Y; Liu, Rui R; Ou, Qiuxiang Q; Guo, Qinhao Q; Shen, Yi Y; Wu, Xue X; Shao, Yang Y; Bao, Hua H; Wu, Xiaohua X

Publication Date: 2022-05-16

Variant appearance in text: TP53: 524G>A; R175H

PubMed Link: 35578198

Variant Present in the following documents:

• 12885_2022_9602_MOESM9_ESM.xlsx

View BVdb publication page

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Liquid Biopsy in Squamous Cell Carcinoma of the Esophagus and of the Head and Neck.

Frontiers In Medicine

Iacob, Razvan R; Mandea, Matei M; Iacob, Speranta S; Pietrosanu, Catalina C; Paul, Doru D; Hainarosie, Razvan R; Gheorghe, Cristian C

Publication Date: 2022

Variant appearance in text: TP53: R175H

PubMed Link: 35572996

Variant Present in the following documents:

• fmed-09-827297.pdf

View BVdb publication page

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T Cell Defects: New Insights Into the Primary Resistance Factor to CD19/CD22 Cocktail CAR T-Cell Immunotherapy in Diffuse Large B-Cell Lymphoma.

Frontiers In Immunology

Wang, Jiachen J; Shen, Kefeng K; Mu, Wei W; Li, Weigang W; Zhang, Meilan M; Zhang, Wei W; Li, Zhe Z; Ge, Tong T; Zhu, Zhoujie Z; Zhang, Shangkun S; Chen, Caixia C; Xing, Shugang S; Zhu, Li L; Chen, Liting L; Wang, Na N; Huang, Liang L; Li, Dengju D; Xiao, Min M; Zhou, Jianfeng J

Publication Date: 2022

Variant appearance in text: TP53: 524G>A; Arg175His; rs28934578

PubMed Link: 35572515

Variant Present in the following documents:

• Table_2.xlsx

View BVdb publication page

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mRNA Subtype of Cancer-Associated Fibroblasts Significantly Affects Key Characteristics of Head and Neck Cancer Cells.

Cancers

Peltanová, Barbora B; Holcová Polanská, Hana H; Raudenská, Martina M; Balvan, Jan J; Navrátil, Jiří J; Vičar, Tomáš T; Gumulec, Jaromír J; Čechová, Barbora B; Kräter, Martin M; Guck, Jochen J; Kalfeřt, David D; Grega, Marek M; Plzák, Jan J; Betka, Jan J; Masařík, Michal M

Publication Date: 2022-05-03

Variant appearance in text: p53: R175H

PubMed Link: 35565415

Variant Present in the following documents:

• cancers-14-02286.pdf

View BVdb publication page

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Space- and Time-Resolved Metabolomics of a High-Grade Serous Ovarian Cancer Mouse Model.

Cancers

Sah, Samyukta S; Ma, Xin X; Botros, Andro A; Gaul, David A DA; Yun, Sylvia R SR; Park, Eun Young EY; Kim, Olga O; Moore, Samuel G SG; Kim, Jaeyeon J; Fernández, Facundo M FM

Publication Date: 2022-04-30

Variant appearance in text: p53: R175H

PubMed Link: 35565391

Variant Present in the following documents:

• cancers-14-02262.pdf

View BVdb publication page

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The Role of E3 Ligase Pirh2 in Disease.

Cells

Daks, Alexandra A; Fedorova, Olga O; Parfenyev, Sergey S; Nevzorov, Ivan I; Shuvalov, Oleg O; Barlev, Nickolai A NA

Publication Date: 2022-04-30

Variant appearance in text: p53: R175H

PubMed Link: 35563824

Variant Present in the following documents:

• cells-11-01515.pdf

View BVdb publication page

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Inflammation: A New Look at an Old Problem.

International Journal Of Molecular Sciences

Gusev, Evgenii E; Zhuravleva, Yulia Y

Publication Date: 2022-04-21

Variant appearance in text: p53: R175H

PubMed Link: 35562986

Variant Present in the following documents:

• ijms-23-04596.pdf

View BVdb publication page

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Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways.

Nature Communications

Zhang, Yiqun Y; Chen, Fengju F; Chandrashekar, Darshan S DS; Varambally, Sooryanarayana S; Creighton, Chad J CJ

Publication Date: 2022-05-13

Variant appearance in text: p53: R175H

PubMed Link: 35562349

Variant Present in the following documents:

• 41467_2022_30342_MOESM4_ESM.xlsx

View BVdb publication page

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Relevance of Amorphous and Amyloid-Like Aggregates of the p53 Core Domain to Loss of its DNA-Binding Activity.

Frontiers In Molecular Biosciences

Hibino, Emi E; Tenno, Takeshi T; Hiroaki, Hidekazu H

Publication Date: 2022

Variant appearance in text: p53: R175H

PubMed Link: 35558561

Variant Present in the following documents:

• fmolb-09-869851.pdf

View BVdb publication page

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Fundamental immune-oncogenicity trade-offs define driver mutation fitness.

Nature

Hoyos, David D; Zappasodi, Roberta R; Schulze, Isabell I; Sethna, Zachary Z; de Andrade, Kelvin César KC; Bajorin, Dean F DF; Bandlamundi, Chaitanya C; Callahan, Margaret K MK; Funt, Samuel A SA; Hadrup, Sine R SR; Holm, Jeppe S JS; Rosenberg, Jonathan E JE; Shah, Sohrab P SP; Vázquez-García, Ignacio I; Weigelt, Britta B; Wu, Michelle M; Zamarin, Dmitriy D; Campitelli, Laura F LF; Osborne, Edward J EJ; Klinger, Mark M; Robins, Harlan S HS; Khincha, Payal P PP; Savage, Sharon A SA; Balachandran, Vinod P VP; Wolchok, Jedd D JD; Hellmann, Matthew D MD; Merghoub, Taha T; Levine, Arnold J AJ; Łuksza, Marta M; Greenbaum, Benjamin D BD

Publication Date: 2022-05-11

Variant appearance in text: p53: R175H

PubMed Link: 35545680

Variant Present in the following documents:

• Main text
• 41586_2022_Article_4696.pdf
• 41586_2022_4696_MOESM3_ESM.pdf

View BVdb publication page

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Mutual exclusivity of ESR1 and TP53 mutations in endocrine resistant metastatic breast cancer.

Npj Breast Cancer

Li, Zheqi Z; Spoelstra, Nicole S NS; Sikora, Matthew J MJ; Sams, Sharon B SB; Elias, Anthony A; Richer, Jennifer K JK; Lee, Adrian V AV; Oesterreich, Steffi S

Publication Date: 2022-05-10

Variant appearance in text: p53: R175H

PubMed Link: 35538119

Variant Present in the following documents:

• 41523_2022_Article_426.pdf
• 41523_2022_426_MOESM1_ESM.pdf

View BVdb publication page

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Identification of biomarkers of response to preoperative talazoparib monotherapy in treatment naïve gBRCA+ breast cancers.

Npj Breast Cancer

Liu, Xuan X; Ge, Zhongqi Z; Yang, Fei F; Contreras, Alejandro A; Lee, Sanghoon S; White, Jason B JB; Lu, Yiling Y; Labrie, Marilyne M; Arun, Banu K BK; Moulder, Stacy L SL; Mills, Gordon B GB; Piwnica-Worms, Helen H; Litton, Jennifer K JK; Chang, Jeffrey T JT

Publication Date: 2022-05-10

Variant appearance in text: TP53: R175H

PubMed Link: 35538088

Variant Present in the following documents:

• 41523_2022_Article_427.pdf

View BVdb publication page

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Paclitaxel and cisplatin with or without cetuximab in metastatic esophageal squamous cell carcinoma: a randomized, multicenter phase II trial.

Innovation (Cambridge (Mass.))

Lu, Zhihao Z; Zhang, Yanqiao Y; Fan, Qingxia Q; Pan, Yueyin Y; Jiang, Da D; Lu, Ping P; Zhang, Jingdong J; Yuan, Xianglin X; Feng, Jifeng J; Yang, Shujun S; Yue, Wenbin W; Zhao, Lin L; Xu, Yunhua Y; Luo, Jinhua J; Shen, Lin L

Publication Date: 2022-05-10

Variant appearance in text: TP53: 524G>A; R175H

PubMed Link: 35509869

Variant Present in the following documents:

• mmc2.xlsx

View BVdb publication page

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Establishment of patient-derived organoids and a characterization-based drug discovery platform for treatment of pancreatic cancer.

Bmc Cancer

Watanabe, Sadanori S; Yogo, Akitada A; Otsubo, Tsuguteru T; Umehara, Hiroki H; Oishi, Jun J; Kodo, Toru T; Masui, Toshihiko T; Takaishi, Shigeo S; Seno, Hiroshi H; Uemoto, Shinji S; Hatano, Etsuro E

Publication Date: 2022-05-03

Variant appearance in text: rs28934578

PubMed Link: 35505283

Variant Present in the following documents:

• 12885_2022_9619_MOESM1_ESM.xlsx

View BVdb publication page

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p53 and Zinc: A Malleable Relationship.

Frontiers In Molecular Biosciences

Ha, Jeung-Hoi JH; Prela, Orjola O; Carpizo, Darren R DR; Loh, Stewart N SN

Publication Date: 2022

Variant appearance in text: p53: R175H

PubMed Link: 35495631

Variant Present in the following documents:

• fmolb-09-895887.pdf

View BVdb publication page

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Targeting TP53-Mutated Acute Myeloid Leukemia: Research and Clinical Developments.

Oncotargets And Therapy

Granowicz, Eric M EM; Jonas, Brian A BA

Publication Date: 2022

Variant appearance in text: TP53: R175H

PubMed Link: 35479302

Variant Present in the following documents:

• ott-15-423.pdf

View BVdb publication page

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Germline MBD4 deficiency causes a multi-tumor predisposition syndrome.

American Journal Of Human Genetics

Palles, Claire C; West, Hannah D HD; Chew, Edward E; Galavotti, Sara S; Flensburg, Christoffer C; Grolleman, Judith E JE; Jansen, Erik A M EAM; Curley, Helen H; Chegwidden, Laura L; Arbe-Barnes, Edward H EH; Lander, Nicola N; Truscott, Rebekah R; Pagan, Judith J; Bajel, Ashish A; Sherwood, Kitty K; Martin, Lynn L; Thomas, Huw H; Georgiou, Demetra D; Fostira, Florentia F; Goldberg, Yael Y; Adams, David J DJ; van der Biezen, Simone A M SAM; Christie, Michael M; Clendenning, Mark M; Thomas, Laura E LE; Deltas, Constantinos C; Dimovski, Aleksandar J AJ; Dymerska, Dagmara D; Lubinski, Jan J; Mahmood, Khalid K; van der Post, Rachel S RS; Sanders, Mathijs M; Weitz, Jürgen J; Taylor, Jenny C JC; Turnbull, Clare C; Vreede, Lilian L; van Wezel, Tom T; Whalley, Celina C; Arnedo-Pac, Claudia C; Caravagna, Giulio G; Cross, William W; Chubb, Daniel D; Frangou, Anna A; Gruber, Andreas J AJ; Kinnersley, Ben B; Noyvert, Boris B; Church, David D; Graham, Trevor T; Houlston, Richard R; Lopez-Bigas, Nuria N; Sottoriva, Andrea A; Wedge, David D; , ; , ; , ; Jenkins, Mark A MA; Kuiper, Roland P RP; Roberts, Andrew W AW; Cheadle, Jeremy P JP; Ligtenberg, Marjolijn J L MJL; Hoogerbrugge, Nicoline N; Koelzer, Viktor H VH; Rivas, Andres Dacal AD; Winship, Ingrid M IM; Ponte, Clara Ruiz CR; Buchanan, Daniel D DD; Power, Derek G DG; Green, Andrew A; Tomlinson, Ian P M IPM; Sampson, Julian R JR; Majewski, Ian J IJ; de Voer, Richarda M RM

Publication Date: 2022-04-20

Variant appearance in text: TP53: R175H

PubMed Link: 35460607

Variant Present in the following documents:

• mmc2.xlsx

View BVdb publication page

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TCRP1 activated by mutant p53 promotes NSCLC proliferation via inhibiting FOXO3a.

Oncogenesis

Liu, Hao H; Jia, Xiaoting X; Luo, Kai K; Chen, Xiangzhou X; Zhang, Zhijie Z; Chen, Danyang D; Gu, Yixue Y; He, Zhimin Z; Zheng, Guopei G

Publication Date: 2022-04-22

Variant appearance in text: p53: R175H

PubMed Link: 35459265

Variant Present in the following documents:

• 41389_2022_Article_392.pdf

View BVdb publication page

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Mixed Neuroendocrine Non-Neuroendocrine Neoplasms of the Gastrointestinal Tract: A Case Series.

Healthcare (Basel, Switzerland)

Guerrera, Luigi Pio LP; Suarato, Gabriella G; Napolitano, Rossella R; Perrone, Alessandra A; Caputo, Vincenza V; Ventriglia, Anna A; Martini, Giulia G; Della Corte, Carminia Maria CM; Orditura, Michele M; Martinelli, Erika E; Ciardiello, Fortunato F; Montella, Marco M; Franco, Renato R; Troiani, Teresa T; Napolitano, Stefania S

Publication Date: 2022-04-11

Variant appearance in text: TP53: R175H

PubMed Link: 35455885

Variant Present in the following documents:

• healthcare-10-00708.pdf

View BVdb publication page

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Advanced Strategies for Therapeutic Targeting of Wild-Type and Mutant p53 in Cancer.

Biomolecules

Zhang, Shengliang S; Carlsen, Lindsey L; Hernandez Borrero, Liz L; Seyhan, Attila A AA; Tian, Xiaobing X; El-Deiry, Wafik S WS

Publication Date: 2022-04-06

Variant appearance in text: p53: R175H

PubMed Link: 35454137

Variant Present in the following documents:

• biomolecules-12-00548.pdf

View BVdb publication page

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Integrated profiling of human pancreatic cancer organoids reveals chromatin accessibility features associated with drug sensitivity.

Nature Communications

Shi, Xiaohan X; Li, Yunguang Y; Yuan, Qiuyue Q; Tang, Shijie S; Guo, Shiwei S; Zhang, Yehan Y; He, Juan J; Zhang, Xiaoyu X; Han, Ming M; Liu, Zhuang Z; Zhu, Yiqin Y; Gao, Suizhi S; Wang, Huan H; Xu, Xiongfei X; Zheng, Kailian K; Jing, Wei W; Chen, Luonan L; Wang, Yong Y; Jin, Gang G; Gao, Dong D

Publication Date: 2022-04-21

Variant appearance in text: TP53: R175H

PubMed Link: 35449156

Variant Present in the following documents:

• 41467_2022_29857_MOESM5_ESM.xlsx

View BVdb publication page

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5-Hydroxymethylcytosine (5hmC) at or near cancer mutation hot spots as potential targets for early cancer detection.

Bmc Research Notes

Lu, Michael J MJ; Lu, Yabin Y

Publication Date: 2022-04-21

Variant appearance in text: TP53: 524G>A; R175H

PubMed Link: 35449110

Variant Present in the following documents:

• 13104_2022_Article_6028.pdf

View BVdb publication page

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CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition.

Nature

Gallo, David D; Young, Jordan T F JTF; Fourtounis, Jimmy J; Martino, Giovanni G; Álvarez-Quilón, Alejandro A; Bernier, Cynthia C; Duffy, Nicole M NM; Papp, Robert R; Roulston, Anne A; Stocco, Rino R; Szychowski, Janek J; Veloso, Artur A; Alam, Hunain H; Baruah, Prasamit S PS; Fortin, Alexanne Bonneau AB; Bowlan, Julian J; Chaudhary, Natasha N; Desjardins, Jessica J; Dietrich, Evelyne E; Fournier, Sara S; Fugère-Desjardins, Chloe C; Goullet de Rugy, Theo T; Leclaire, Marie-Eve ME; Liu, Bingcan B; Bhaskaran, Vivek V; Mamane, Yael Y; Melo, Henrique H; Nicolas, Olivier O; Singhania, Akul A; Szilard, Rachel K RK; Tkáč, Ján J; Yin, Shou Yun SY; Morris, Stephen J SJ; Zinda, Michael M; Marshall, C Gary CG; Durocher, Daniel D

Publication Date: 2022-04-20

Variant appearance in text: TP53: R175H

PubMed Link: 35444283

Variant Present in the following documents:

• 41586_2022_Article_4638.pdf

View BVdb publication page

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PIM1 genetic alterations associated with distinct molecular profiles, phenotypes and drug responses in diffuse large B-cell lymphoma.

Clinical And Translational Medicine

Zhang, Huilai H; Lu, Yaxiao Y; Zhang, Tingting T; Guan, Qingpei Q; Wang, Xiaoxuan X; Guo, Yixian Y; Li, Lanfang L; Qiu, Lihua L; Qian, Zhengzi Z; Zhou, Shiyong S; Gong, Wenchen W; Meng, Bin B; Ren, Xiubao X; Wang, Xianhuo X

Publication Date: 2022-04

Variant appearance in text: TP53: R175H

PubMed Link: 35415904

Variant Present in the following documents:

• CTM2-12-e808-s003.xlsx

View BVdb publication page

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Mutant p53 achieved Gain-of-Function by promoting tumor growth and immune escape through PHLPP2/AKT/PD-L1 pathway.

International Journal Of Biological Sciences

Liu, Nannan N; Jiang, Xinxiu X; Guo, Leiming L; Zhang, Chuchu C; Jiang, Meimei M; Sun, Zhuoran Z; Zhang, Yizheng Y; Mi, Wunan W; Li, Jiehan J; Fu, Yang Y; Wang, Feng F; Zhang, Lingling L; Zhang, Yingjie Y

Publication Date: 2022

Variant appearance in text: TP53: R175H

PubMed Link: 35414774

Variant Present in the following documents:

• ijbsv18p2419s1.pdf
• ijbsv18p2419.pdf

View BVdb publication page

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Growth factor independence underpins a paroxysmal, aggressive Wnt5aHigh/EphA2Low phenotype in glioblastoma stem cells, conducive to experimental combinatorial therapy.

Journal Of Experimental & Clinical Cancer Research : Cr

Trivieri, Nadia N; Visioli, Alberto A; Mencarelli, Gandino G; Cariglia, Maria Grazia MG; Marongiu, Laura L; Pracella, Riccardo R; Giani, Fabrizio F; Soriano, Amata Amy AA; Barile, Chiara C; Cajola, Laura L; Copetti, Massimiliano M; Palumbo, Orazio O; Legnani, Federico F; DiMeco, Francesco F; Gorgoglione, Leonardo L; Vescovi, Angelo L AL; Binda, Elena E

Publication Date: 2022-04-12

Variant appearance in text: TP53: R175H; rs28934578

PubMed Link: 35414102

Variant Present in the following documents:

• 13046_2022_2333_MOESM3_ESM.xlsx
• 13046_2022_2333_MOESM4_ESM.xlsx

View BVdb publication page

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Germline Variants in Cancer Genes from Young Breast Cancer Mexican Patients.

Cancers

Gómez-Flores-Ramos, Liliana L; Barraza-Arellano, Angélica Leticia AL; Mohar, Alejandro A; Trujillo-Martínez, Miguel M; Grimaldo, Lizbeth L; Ortiz-Lopez, Rocío R; Treviño, Víctor V

Publication Date: 2022-03-24

Variant appearance in text: TP53: R175H

PubMed Link: 35406420

Variant Present in the following documents:

• cancers-14-01647.pdf

View BVdb publication page

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Inhibiting the Priming for Cancer in Li-Fraumeni Syndrome.

Cancers

Pantziarka, Pan P; Blagden, Sarah S

Publication Date: 2022-03-23

Variant appearance in text: p53: R175H

PubMed Link: 35406393

Variant Present in the following documents:

• cancers-14-01621.pdf

View BVdb publication page

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Somatic LINE-1 promoter acquisition drives oncogenic FOXR2 activation in pediatric brain tumor.

Acta Neuropathologica

Flasch, Diane A DA; Chen, Xiaolong X; Ju, Bensheng B; Li, Xiaoyu X; Dalton, James J; Mulder, Heather L HL; Easton, John J; Wang, Lu L; Baker, Suzanne J SJ; Chiang, Jason J; Zhang, Jinghui J

Publication Date: 2022-04-11

Variant appearance in text: TP53: R175H

PubMed Link: 35403869

Variant Present in the following documents:

• 401_2022_Article_2420.pdf

View BVdb publication page

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Proof-of-Concept Pilot Study on Comprehensive Spatiotemporal Intra-Patient Heterogeneity for Colorectal Cancer With Liver Metastasis.

Frontiers In Oncology

Kyrochristos, Ioannis D ID; Glantzounis, Georgios K GK; Goussia, Anna A; Eliades, Alexia A; Achilleos, Achilleas A; Tsangaras, Kyriakos K; Hadjidemetriou, Irene I; Elpidorou, Marilena M; Ioannides, Marios M; Koumbaris, George G; Mitsis, Michail M; Patsalis, Philippos C PC; Roukos, Dimitrios D

Publication Date: 2022

Variant appearance in text: TP53: 524G>A

PubMed Link: 35402285

Variant Present in the following documents:

• Table_1.xlsx

View BVdb publication page

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Clinicopathologic and Genomic Features in Triple-Negative Breast Cancer Between Special and No-Special Morphologic Pattern.

Frontiers In Oncology

Li, Ying-Zi YZ; Chen, Bo B; Lin, Xiao-Yi XY; Zhang, Guo-Chun GC; Lai, Jian-Guo JG; Li, Cheukfai C; Lin, Jia-Li JL; Guo, Li-Ping LP; Xiao, Wei-Kai WK; Mok, Hsiaopei H; Ren, Chong-Yang CY; Wen, Ling-Zhu LZ; Cao, Fang-Rong FR; Lin, Xin X; Qi, Xiao-Fang XF; Liu, Yang Y; Liao, Ning N

Publication Date: 2022

Variant appearance in text: TP53: R175H

PubMed Link: 35402236

Variant Present in the following documents:

• fonc-12-830124.pdf

View BVdb publication page

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Integrated genomic analyses identify high-risk factors and actionable targets in T-cell acute lymphoblastic leukemia.

Blood Science (Baltimore, Md.)

Zhu, Haichuan H; Dong, Bingjie B; Zhang, Yingchi Y; Wang, Mei M; Rao, Jianan J; Cui, Bowen B; Liu, Yu Y; Jiang, Qian Q; Wang, Weitao W; Yang, Lu L; Yu, Anqi A; Li, Zongru Z; Liu, Chao C; Zhang, Leping L; Huang, Xiaojun X; Zhu, Xiaofan X; Wu, Hong H

Publication Date: 2022-01

Variant appearance in text: TP53: R175H

PubMed Link: 35399540

Variant Present in the following documents:

• bls-4-16-s005.xlsx

View BVdb publication page

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Phase 1b study of berzosertib and cisplatin in patients with advanced triple-negative breast cancer.

Npj Breast Cancer

Telli, Melinda L ML; Tolaney, Sara M SM; Shapiro, Geoffrey I GI; Middleton, Mark M; Lord, Simon R SR; Arkenau, Hendrik Tobias HT; Tutt, Andrew A; Abramson, Vandana V; Dean, Emma E; Haddad, Tufia C TC; Wesolowski, Robert R; Ferrer-Playan, Jordi J; Goddemeier, Thomas T; Grombacher, Thomas T; Dong, Jennifer J; Fleuranceau-Morel, Patricia P; Diaz-Padilla, Ivan I; Plummer, Ruth R

Publication Date: 2022-04-07

Variant appearance in text: TP53: R175H

PubMed Link: 35393425

Variant Present in the following documents:

• 41523_2022_406_MOESM1_ESM.pdf

View BVdb publication page

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Deciphering the Increased Prevalence of TP53 Mutations in Metastatic Prostate Cancer.

Cancer Informatics

Zhang, Wensheng W; Dong, Yan Y; Sartor, Oliver O; Zhang, Kun K

Publication Date: 2022

Variant appearance in text: TP53: 524G>A

PubMed Link: 35392296

Variant Present in the following documents:

• 10.1177_11769351221087046.pdf

View BVdb publication page

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Genomic clonal evolution correlated with phenotype and prognosis in gastric cancer.

Clinical And Translational Medicine

Ge, Jie J; Li, Xuan X; Deng, Zhenghao Z; Gao, Xuan X; Liu, Yaoyao Y; Xiong, Xingui X; Zhao, Xianhui X; Peng, Huan H; Yi, Xin X; Xia, Xuefeng X; Chen, Zihua Z; Li, Lifeng L; Zhou, Haiyan H; Liu, Heli H

Publication Date: 2022-04

Variant appearance in text: TP53: 524G>A; R175H

PubMed Link: 35384329

Variant Present in the following documents:

• CTM2-12-e799-s006.xlsx

View BVdb publication page

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A molecular approach integrating genomic and DNA methylation profiling for tissue of origin identification in lung-specific cancer of unknown primary.

Journal Of Translational Medicine

Chen, Kaiyan K; Zhang, Fanrong F; Yu, Xiaoqing X; Huang, Zhiyu Z; Gong, Lei L; Xu, Yanjun Y; Li, Hui H; Yu, Sizhe S; Fan, Yun Y

Publication Date: 2022-04-05

Variant appearance in text: TP53: R175H

PubMed Link: 35382836

Variant Present in the following documents:

• 12967_2022_Article_3362.pdf

View BVdb publication page

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Mutant p53: it's not all one and the same.

Cell Death And Differentiation

Kennedy, Margaret C MC; Lowe, Scott W SW

Publication Date: 2022-03-31

Variant appearance in text: p53: R175H

PubMed Link: 35361963

Variant Present in the following documents:

• 41418_2022_Article_989.pdf

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Clinical utility of comprehensive genomic profiling in Japan: Result of PROFILE-F study.

Plos One

Aoyagi, Yasuko Y; Kano, Yoshihito Y; Tohyama, Kohki K; Matsudera, Shotaro S; Kumaki, Yuichi Y; Takahashi, Kenta K; Mitsumura, Takahiro T; Harada, Yohei Y; Sato, Akemi A; Nakamura, Hideaki H; Sueoka, Eisaburo E; Aragane, Naoko N; Kimura, Koichiro K; Onishi, Iichiro I; Takemoto, Akira A; Akahoshi, Keiichi K; Ono, Hiroaki H; Ishikawa, Toshiaki T; Tokunaga, Masanori M; Nakagawa, Tsuyoshi T; Oshima, Noriko N; Nakamura, Reiko R; Takagi, Masatoshi M; Asakage, Takahiro T; Uetake, Hiroyuki H; Tanabe, Minoru M; Miyake, Satoshi S; Kinugasa, Yusuke Y; Ikeda, Sadakatsu S

Publication Date: 2022

Variant appearance in text: TP53: R175H

PubMed Link: 35358259

Variant Present in the following documents:

• pone.0266112.s001.xlsx

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Non-human primate papillomavirus E6-mediated p53 degradation reveals ancient evolutionary adaptation of carcinogenic phenotype to host niche.

Plos Pathogens

Long, Teng T; Burk, Robert D RD; Chan, Paul K S PKS; Chen, Zigui Z

Publication Date: 2022-03-25

Variant appearance in text: p53: R175H

PubMed Link: 35333912

Variant Present in the following documents:

• ppat.1010444.pdf

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TP53 Expression and Mutational Analysis in Hematological Malignancy in Jeddah, Saudi Arabia.

Diagnostics (Basel, Switzerland)

Alkhatabi, Heba H; Yasin, Elrashed B EB; Mirza, Zeenat Z; Alserihi, Raed R; Felimban, Raed R; Elaimi, Aisha A; Shaabad, Manal M; Alharbi, Lina L; Ahmed, Hameeda H; Alameer, Abdulrahman M AM; Mathkoor, Abdullah Ebraheem AE; Barefah, Ahmed Salleh AS

Publication Date: 2022-03-16

Variant appearance in text: rs28934578

PubMed Link: 35328276

Variant Present in the following documents:

• diagnostics-12-00724.pdf

View BVdb publication page

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NAMPT Inhibitor and P73 Activator Represses P53 R175H Mutated HNSCC Cell Proliferation in a Synergistic Manner.

Biomolecules

Cai, Bi-He BH; Bai, Zhi-Yu ZY; Lien, Ching-Feng CF; Yu, Si-Jie SJ; Lu, Rui-Yu RY; Wu, Ming-Han MH; Wu, Wei-Chen WC; Chen, Chia-Chi CC; Hsu, Yi-Chiang YC

Publication Date: 2022-03-12

Variant appearance in text: p53: R175H

PubMed Link: 35327630

Variant Present in the following documents:

• biomolecules-12-00438.pdf

View BVdb publication page

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Response prediction and risk stratification of patients with rectal cancer after neoadjuvant therapy through an analysis of circulating tumour DNA.

Ebiomedicine

Liu, Wenyang W; Li, Yifei Y; Tang, Yuan Y; Song, Qianqian Q; Wang, Jingjing J; Li, Ning N; Chen, Silin S; Shi, Jinming J; Wang, Shulian S; Li, Yexiong Y; Jiao, Yuchen Y; Zeng, Yixin Y; Jin, Jing J

Publication Date: 2022-03-17

Variant appearance in text: TP53: 524G>A

PubMed Link: 35306340

Variant Present in the following documents:

• mmc3.xlsx

View BVdb publication page

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Parecoxib inhibits esophageal squamous cell carcinoma progression via the PDK1-AKT pathway.

Cellular & Molecular Biology Letters

Huang, Han-Ming HM; Huang, Xiao-Yu XY; Wu, Shao-Ping SP; Chen, Can-Keng CK; He, Xin-Hua XH; Zhang, Yong-Fa YF

Publication Date: 2022-03-19

Variant appearance in text: p53: R175H

PubMed Link: 35305553

Variant Present in the following documents:

• 11658_2022_Article_324.pdf

View BVdb publication page

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Zebrafish imaging reveals TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesis.

Nature Communications

Haraoka, Yukinari Y; Akieda, Yuki Y; Nagai, Yuri Y; Mogi, Chihiro C; Ishitani, Tohru T

Publication Date: 2022-03-18

Variant appearance in text: TP53: R175H

PubMed Link: 35304872

Variant Present in the following documents:

• 41467_2022_29061_MOESM2_ESM.pdf
• 41467_2022_29061_MOESM1_ESM.pdf

View BVdb publication page

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Dynamic changes in gene alterations during chemotherapy in metastatic castrate resistant prostate cancer.

Scientific Reports

Tan, Winston W; Zheng, Tiantian T; Wang, Amy A; Roacho, Joanna J; Thao, Seng S; Du, Pan P; Jia, Shidong S; Yu, Jianjun J; King, Bonnie L BL; Kohli, Manish M

Publication Date: 2022-03-18

Variant appearance in text: TP53: 524G>A; Arg175His

PubMed Link: 35304525

Variant Present in the following documents:

• 41598_2022_8520_MOESM2_ESM.xlsx

View BVdb publication page

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p16INK4A-deficiency predicts response to combined HER2 and CDK4/6 inhibition in HER2+ breast cancer brain metastases.

Nature Communications

Ni, Jing J; Kabraji, Sheheryar S; Xie, Shaozhen S; Wang, Yanzhi Y; Pan, Peichen P; He, Xiaofang X; Liu, Zongming Z; Leone, Jose Palbo JP; Long, Henry W HW; Brown, Myles A MA; Winer, Eric P EP; Dillon, Deborah A R DAR; Lin, Nancy U NU; Zhao, Jean J JJ

Publication Date: 2022-03-18

Variant appearance in text: TP53: R175H

PubMed Link: 35304445

Variant Present in the following documents:

• 41467_2022_29081_MOESM3_ESM.xlsx

View BVdb publication page

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A general calculus of fitness landscapes finds genes under selection in cancers.

Genome Research

Hsu, Teng-Kuei TK; Asmussen, Jennifer Kay JK; Koire, Amanda Michele AM; Choi, Byung-Kwon BK; Gadhikar, Mayur Arvind MA; Huh, Eunna E; Lin, Chih-Hsu CH; Konecki, Daniel Manuka DM; Kim, Young Won YW; Pickering, Curtis C; Kimmel, Marek M; Donehower, Lawrence Allen LA; Frederick, Mitchell Jay MJ; Myers, Jeffrey N JN; Katsonis, Panagiotis P; Lichtarge, Olivier O

Publication Date: 2022-03-17

Variant appearance in text: TP53: R175H

PubMed Link: 35301263

Variant Present in the following documents:

• Main text
• 916.pdf

View BVdb publication page

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Perioperative Circulating Tumor DNA Enables Identification of Patients with Poor Prognosis in Upper Tract Urothelial Carcinoma.

Cancer Science

Nakano, Kosuke K; Koh, Yoko Y; Yamamichi, Gaku G; Yumiba, Satoru S; Tomiyama, Eisuke E; Matsushita, Makoto M; Hayashi, Yujiro Y; Wang, Cong C; Ishizuya, Yu Y; Yamamoto, Yoshiyuki Y; Kato, Taigo T; Hatano, Koji K; Kawashima, Atsunari A; Ujike, Takeshi T; Fujita, Kazutoshi K; Kiyotani, Kazuma K; Katayama, Kotoe K; Yamaguchi, Rui R; Imoto, Seiya S; Imamura, Ryoichi R; Nonomura, Norio N; Uemura, Motohide M

Publication Date: 2022-03-16

Variant appearance in text: TP53: R175H

PubMed Link: 35293110

Variant Present in the following documents:

• CAS-113-1830-s004.xlsx

View BVdb publication page

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Case Report Series: Aggressive HR Deficient Colorectal Cancers Related to BRCA1 Pathogenic Germline Variants.

Frontiers In Oncology

Freire, Maria Valeria MV; Martin, Marie M; Thissen, Romain R; Van Marcke, Cédric C; Segers, Karin K; Sépulchre, Edith E; Leroi, Natacha N; Lété, Céline C; Fasquelle, Corinne C; Radermacher, Jean J; Gokburun, Yeter Y; Collignon, Joelle J; Sacré, Anne A; Josse, Claire C; Palmeira, Leonor L; Bours, Vincent V

Publication Date: 2022

Variant appearance in text: TP53: 524G>A; Arg175His

PubMed Link: 35280729

Variant Present in the following documents:

• fonc-12-835581.pdf

View BVdb publication page

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The Landscape of Actionable Genomic Alterations by Next-Generation Sequencing in Tumor Tissue Versus Circulating Tumor DNA in Chinese Patients With Non-Small Cell Lung Cancer.

Frontiers In Oncology

Cai, Jun J; Jiang, Huihui H; Li, Shuqing S; Yan, Xiaoxia X; Wang, Meng M; Li, Na N; Zhu, Cuimin C; Dong, Hui H; Wang, Dongjuan D; Xu, Yue Y; Xie, Hui H; Wu, Shouxin S; Lou, Jingwei J; Zhao, Jiangman J; Li, Qingshan Q

Publication Date: 2021

Variant appearance in text: TP53: R175H

PubMed Link: 35273907

Variant Present in the following documents:

• Table_8.xlsx

View BVdb publication page

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Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications

Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L

Publication Date: 2022-03-10

Variant appearance in text: TP53: 524G>A; R175H

PubMed Link: 35273153

Variant Present in the following documents:

• 41467_2022_28840_MOESM7_ESM.xlsx

View BVdb publication page

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Identification of Neoantigens in Cancer Cells as Targets for Immunotherapy.

International Journal Of Molecular Sciences

Okada, Masahiro M; Shimizu, Kanako K; Fujii, Shin-Ichiro SI

Publication Date: 2022-02-26

Variant appearance in text: TP53: R175H

PubMed Link: 35269735

Variant Present in the following documents:

• ijms-23-02594.pdf

View BVdb publication page

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Cranberry Polyphenols in Esophageal Cancer Inhibition: New Insights.

Nutrients

Weh, Katherine M KM; Zhang, Yun Y; Howard, Connor L CL; Howell, Amy B AB; Clarke, Jennifer L JL; Kresty, Laura A LA

Publication Date: 2022-02-24

Variant appearance in text: TP53: 524G>A

PubMed Link: 35267943

Variant Present in the following documents:

• nutrients-14-00969.pdf

View BVdb publication page

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Estrogen Receptor-Beta2 (ERβ2)-Mutant p53-FOXM1 Axis: A Novel Driver of Proliferation, Chemoresistance, and Disease Progression in High Grade Serous Ovarian Cancer (HGSOC).

Cancers

Oturkar, Chetan C CC; Gandhi, Nishant N; Rao, Pramod P; Eng, Kevin H KH; Miller, Austin A; Singh, Prashant K PK; Zsiros, Emese E; Odunsi, Kunle O KO; Das, Gokul M GM

Publication Date: 2022-02-22

Variant appearance in text: p53: R175H

PubMed Link: 35267428

Variant Present in the following documents:

• cancers-14-01120.pdf

View BVdb publication page

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Characterization of disease-propagating stem cells responsible for myeloproliferative neoplasm-blast phase.

Jci Insight

Wang, Xiaoli X; Rampal, Raajit K RK; Hu, Cing Siang CS; Tripodi, Joseph J; Farnoud, Noushin N; Petersen, Bruce B; Rossi, Michael R MR; Patel, Minal M; McGovern, Erin E; Najfeld, Vesna V; Iancu-Rubin, Camelia C; Lu, Min M; Davis, Andrew A; Kremyanskaya, Marina M; Weinberg, Rona Singer RS; Mascarenhas, John J; Hoffman, Ronald R

Publication Date: 2022-03-08

Variant appearance in text: TP53: R175H

PubMed Link: 35259128

Variant Present in the following documents:

• jciinsight-7-156534-s067.xlsx

View BVdb publication page

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Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog.

Cell Death & Disease

Zhang, Qiang Q; Balourdas, Dimitrios-Ilias DI; Baron, Bruno B; Senitzki, Alon A; Haran, Tali E TE; Wiman, Klas G KG; Soussi, Thierry T; Joerger, Andreas C AC

Publication Date: 2022-03-07

Variant appearance in text: p53: R175H

PubMed Link: 35256607

Variant Present in the following documents:

• 41419_2022_4653_MOESM1_ESM.pdf
• 41419_2022_Article_4653.pdf

View BVdb publication page

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Landscape of TP53 Alterations in Chronic Lymphocytic Leukemia via Data Mining Mutation Databases.

Frontiers In Oncology

Soussi, Thierry T; Baliakas, Panagiotis P

Publication Date: 2022

Variant appearance in text: TP53: Arg175His

PubMed Link: 35251978

Variant Present in the following documents:

• fonc-12-808886.pdf

View BVdb publication page

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Complete Response With Cetuximab-Based Treatment of Metastatic Colorectal Cancers: Two Case Reports and Literature Review.

Frontiers In Oncology

Wei, Li L; Lin, Zexiao Z; Xie, Sidong S; Ruan, Danyun D; Jiang, Wen W; Cui, Yueli Y; Liu, Sisi S; Wang, Tiantian T; Chen, Zhanhong Z; Lin, Qu Q

Publication Date: 2022

Variant appearance in text: TP53: 524G>A

PubMed Link: 35251973

Variant Present in the following documents:

• fonc-12-798515.pdf

View BVdb publication page

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Rapid recruitment of p53 to DNA damage sites directs DNA repair choice and integrity.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Wang, Yu-Hsiu YH; Ho, Teresa L F TLF; Hariharan, Anushya A; Goh, Hui Chin HC; Wong, Yao Liang YL; Verkaik, Nicole S NS; Lee, May Yin MY; Tam, Wai Leong WL; van Gent, Dik C DC; Venkitaraman, Ashok R AR; Sheetz, Michael P MP; Lane, David P DP

Publication Date: 2022-03-08

Variant appearance in text: p53: R175H

PubMed Link: 35235448

Variant Present in the following documents:

• pnas.202113233.pdf

View BVdb publication page

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Partial p53 reactivation is sufficient to induce cancer regression.

Journal Of Experimental & Clinical Cancer Research : Cr

Klimovich, Boris B; Meyer, Laura L; Merle, Nastasja N; Neumann, Michelle M; König, Alexander M AM; Ananikidis, Nikolaos N; Keber, Corinna U CU; Elmshäuser, Sabrina S; Timofeev, Oleg O; Stiewe, Thorsten T

Publication Date: 2022-03-02

Variant appearance in text: p53: R175H

PubMed Link: 35232479

Variant Present in the following documents:

• 13046_2022_Article_2269.pdf

View BVdb publication page

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T Cell Recognition of Tumor Neoantigens and Insights Into T Cell Immunotherapy.

Frontiers In Immunology

Sim, Malcolm J W MJW; Sun, Peter D PD

Publication Date: 2022

Variant appearance in text: TP53: R175H

PubMed Link: 35222422

Variant Present in the following documents:

• fimmu-13-833017.pdf

View BVdb publication page

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The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer

Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J

Publication Date: 2022-02

Variant appearance in text: TP53: Arg175His

PubMed Link: 35221333

Variant Present in the following documents:

• 43018_2022_332_MOESM3_ESM.xlsx

View BVdb publication page

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Phosphoproteomic profiling of T cell acute lymphoblastic leukemia reveals targetable kinases and combination treatment strategies.

Nature Communications

Cordo', Valentina V; Meijer, Mariska T MT; Hagelaar, Rico R; de Goeij-de Haas, Richard R RR; Poort, Vera M VM; Henneman, Alex A AA; Piersma, Sander R SR; Pham, Thang V TV; Oshima, Koichi K; Ferrando, Adolfo A AA; Zaman, Guido J R GJR; Jimenez, Connie R CR; Meijerink, Jules P P JPP

Publication Date: 2022-02-25

Variant appearance in text: TP53: R175H

PubMed Link: 35217681

Variant Present in the following documents:

• 41467_2022_28682_MOESM4_ESM.xlsx

View BVdb publication page

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Experimental Nuclear Medicine Meets Tumor Biology.

Pharmaceuticals (Basel, Switzerland)

Balber, Theresa T; Tran, Loan L; Benčurová, Katarína K; Raitanen, Julia J; Egger, Gerda G; Mitterhauser, Markus M

Publication Date: 2022-02-14

Variant appearance in text: p53: R175H

PubMed Link: 35215337

Variant Present in the following documents:

• pharmaceuticals-15-00227.pdf

View BVdb publication page

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Neoantigen: A Promising Target for the Immunotherapy of Colorectal Cancer.

Disease Markers

Zheng, Yue Y; Fu, Yang Y; Wang, Pei-Pei PP; Ding, Zhen-Yu ZY

Publication Date: 2022

Variant appearance in text: TP53: R175H

PubMed Link: 35211210

Variant Present in the following documents:

• DM2022-8270305.pdf

View BVdb publication page

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p53 Signaling on Microenvironment and Its Contribution to Tissue Chemoresistance.

Membranes

Souza, Leonel Cardozo de Menezes E LCME; Faletti, Anderson A; Veríssimo, Carla Pires CP; Stelling, Mariana Paranhos MP; Borges, Helena Lobo HL

Publication Date: 2022-02-09

Variant appearance in text: p53: R175H

PubMed Link: 35207121

Variant Present in the following documents:

• membranes-12-00202.pdf

View BVdb publication page

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Regulation of p53 Function by Formation of Non-Nuclear Heterologous Protein Complexes.

Biomolecules

Zavileyskiy, Lev L; Bunik, Victoria V

Publication Date: 2022-02-18

Variant appearance in text: p53: R175H

PubMed Link: 35204825

Variant Present in the following documents:

• biomolecules-12-00327.pdf

View BVdb publication page

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Tumor Suppressor Role of Wild-Type P53-Dependent Secretome and Its Proteomic Identification in PDAC.

Biomolecules

Butera, Giovanna G; Manfredi, Marcello M; Fiore, Alessandra A; Brandi, Jessica J; Pacchiana, Raffaella R; De Giorgis, Veronica V; Barberis, Elettra E; Vanella, Virginia V; Galasso, Marilisa M; Scupoli, Maria Teresa MT; Marengo, Emilio E; Cecconi, Daniela D; Donadelli, Massimo M

Publication Date: 2022-02-13

Variant appearance in text: p53: R175H

PubMed Link: 35204804

Variant Present in the following documents:

• biomolecules-12-00305.pdf

View BVdb publication page

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USP15 in Cancer and Other Diseases: From Diverse Functionsto Therapeutic Targets.

Biomedicines

Li, Yan-Chi YC; Cai, Song-Wang SW; Shu, Yu-Bin YB; Chen, Mei-Wan MW; Shi, Zhi Z

Publication Date: 2022-02-17

Variant appearance in text: p53: R175H

PubMed Link: 35203682

Variant Present in the following documents:

• biomedicines-10-00474.pdf

View BVdb publication page

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The therapeutic potential of RNA Polymerase I transcription inhibitor, CX-5461, in uterine leiomyosarcoma.

Investigational New Drugs

Kang, Chang-Won CW; Hannan, Katherine M KM; Blackburn, Anneke C AC; Loh, Amos H P AHP; Hong, Kuick Chik KC; Yuan, Goh Jian GJ; Hein, Nadine N; Drygin, Denis D; Hannan, Ross D RD; Coupland, Lucy A LA

Publication Date: 2022-02-24

Variant appearance in text: TP53: R175H

PubMed Link: 35201535

Variant Present in the following documents:

• 10637_2022_Article_1222.pdf

View BVdb publication page

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Recent advances in cancer immunotherapy.

Discover. Oncology

Sun, Qiang Q; Melino, Gerry G; Amelio, Ivano I; Jiang, Jingting J; Wang, Ying Y; Shi, Yufang Y

Publication Date: 2021-08-18

Variant appearance in text: TP53: Arg175His

PubMed Link: 35201440

Variant Present in the following documents:

• 12672_2021_Article_422.pdf

View BVdb publication page

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Curcumin analog HO-3867 triggers apoptotic pathways through activating JNK1/2 signalling in human oral squamous cell carcinoma cells.

Journal Of Cellular And Molecular Medicine

Chen, Chi-Wei CW; Hsieh, Ming-Ju MJ; Ju, Po-Chung PC; Hsieh, Yi-Hsien YH; Su, Chun-Wen CW; Chen, Yen-Lin YL; Yang, Shun-Fa SF; Lin, Chiao-Wen CW

Publication Date: 2022-02-21

Variant appearance in text: p53: R175H

PubMed Link: 35191177

Variant Present in the following documents:

• JCMM-26-2273.pdf

View BVdb publication page

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